Result of FASTA (omim) for
pFN21AE1320
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1320, 431 aa
1>>>pF1KE1320 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.9134+/-0.00056; mu= -5.7276+/- 0.034
mean_var=541.6103+/-119.700, 0's: 0 Z-trim(116.5): 2136 B-trim: 0 in 0/56
Lambda= 0.055110
statistics sampled from 24801 (27640) to 24801 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.324), width: 16
Scan time: 7.610
The best scores are: opt bits E(85289)
NP_001027467 (OMIM: 604984) serine/threonine-prote ( 431) 2841 241.5 3.1e-63
NP_003567 (OMIM: 604984) serine/threonine-protein ( 443) 2748 234.1 5.4e-61
XP_016876283 (OMIM: 604984) PREDICTED: serine/thre ( 517) 2744 233.9 7.3e-61
XP_016876284 (OMIM: 604984) PREDICTED: serine/thre ( 474) 2742 233.7 7.7e-61
XP_005254136 (OMIM: 604984) PREDICTED: serine/thre ( 333) 2203 190.6 5.1e-48
NP_001273578 (OMIM: 604984) serine/threonine-prote ( 412) 2128 184.8 3.6e-46
NP_001258907 (OMIM: 602255) serine/threonine-prote ( 426) 2010 175.4 2.4e-43
NP_006365 (OMIM: 602255) serine/threonine-protein ( 426) 2010 175.4 2.4e-43
NP_001258906 (OMIM: 602255) serine/threonine-prote ( 426) 2010 175.4 2.4e-43
NP_057626 (OMIM: 300547) serine/threonine-protein ( 416) 1833 161.3 4.1e-39
XP_011508795 (OMIM: 602255) PREDICTED: serine/thre ( 376) 1824 160.6 6.4e-39
XP_011508798 (OMIM: 602255) PREDICTED: serine/thre ( 334) 1710 151.4 3.2e-36
XP_016858657 (OMIM: 602255) PREDICTED: serine/thre ( 365) 1710 151.5 3.4e-36
XP_016858658 (OMIM: 602255) PREDICTED: serine/thre ( 365) 1710 151.5 3.4e-36
NP_001258909 (OMIM: 602255) serine/threonine-prote ( 349) 1573 140.6 6.2e-33
NP_001258908 (OMIM: 602255) serine/threonine-prote ( 349) 1573 140.6 6.2e-33
XP_011508796 (OMIM: 602255) PREDICTED: serine/thre ( 352) 1572 140.5 6.6e-33
XP_011508797 (OMIM: 602255) PREDICTED: serine/thre ( 352) 1572 140.5 6.6e-33
XP_016858659 (OMIM: 602255) PREDICTED: serine/thre ( 352) 1572 140.5 6.6e-33
NP_001269235 (OMIM: 602255) serine/threonine-prote ( 352) 1572 140.5 6.6e-33
NP_001269237 (OMIM: 602255) serine/threonine-prote ( 332) 1530 137.1 6.5e-32
NP_001269234 (OMIM: 602255) serine/threonine-prote ( 332) 1530 137.1 6.5e-32
NP_001269236 (OMIM: 602255) serine/threonine-prote ( 332) 1530 137.1 6.5e-32
NP_001035918 (OMIM: 300547) serine/threonine-prote ( 339) 1320 120.4 7e-27
XP_011529651 (OMIM: 300547) PREDICTED: serine/thre ( 318) 1272 116.6 9.5e-26
XP_016858660 (OMIM: 602255) PREDICTED: serine/thre ( 271) 1230 113.1 8.8e-25
XP_011529652 (OMIM: 300547) PREDICTED: serine/thre ( 317) 1194 110.4 7e-24
NP_001035917 (OMIM: 300547) serine/threonine-prote ( 354) 1163 108.0 4.1e-23
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388) 1038 98.1 4.2e-20
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404) 1038 98.1 4.3e-20
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462) 1038 98.2 4.6e-20
XP_005260588 (OMIM: 604965,614868) PREDICTED: seri ( 478) 1038 98.2 4.7e-20
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487) 1038 98.2 4.8e-20
XP_005260587 (OMIM: 604965,614868) PREDICTED: seri ( 503) 1038 98.3 4.9e-20
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456) 1026 97.2 8.9e-20
NP_006272 (OMIM: 605030) serine/threonine-protein ( 491) 1026 97.3 9.3e-20
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 1026 97.3 9.6e-20
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522) 1026 97.3 9.6e-20
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524) 1026 97.3 9.6e-20
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576) 1026 97.4 1e-19
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580) 1026 97.4 1e-19
XP_016883518 (OMIM: 604965,614868) PREDICTED: seri ( 474) 975 93.2 1.5e-18
XP_005260589 (OMIM: 604965,614868) PREDICTED: seri ( 474) 975 93.2 1.5e-18
XP_016883520 (OMIM: 604965,614868) PREDICTED: seri ( 474) 975 93.2 1.5e-18
XP_016883519 (OMIM: 604965,614868) PREDICTED: seri ( 474) 975 93.2 1.5e-18
XP_016883521 (OMIM: 604965,614868) PREDICTED: seri ( 458) 973 93.0 1.7e-18
XP_011527320 (OMIM: 604965,614868) PREDICTED: seri ( 411) 886 86.0 1.9e-16
NP_001257354 (OMIM: 604921) mitogen-activated prot ( 873) 893 87.1 1.9e-16
NP_003609 (OMIM: 604921) mitogen-activated protein ( 894) 893 87.1 2e-16
XP_016873585 (OMIM: 603166) PREDICTED: mitogen-act ( 584) 868 84.8 6.2e-16
>>NP_001027467 (OMIM: 604984) serine/threonine-protein k (431 aa)
initn: 2841 init1: 2841 opt: 2841 Z-score: 1256.2 bits: 241.5 E(85289): 3.1e-63
Smith-Waterman score: 2841; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR
370 380 390 400 410 420
430
pF1KE1 YSLSGGGTSSH
:::::::::::
NP_001 YSLSGGGTSSH
430
>>NP_003567 (OMIM: 604984) serine/threonine-protein kina (443 aa)
initn: 2747 init1: 2747 opt: 2748 Z-score: 1216.1 bits: 234.1 E(85289): 5.4e-61
Smith-Waterman score: 2748; 97.0% identity (97.9% similar) in 434 aa overlap (1-431:10-443)
10 20 30 40
pF1KE1 MAHSPVQSGLP---GMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQK
.: . .. :: : ::::::::::::::::::::::::::::::::::
NP_003 MDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 VVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSAL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 DLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 LTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 FLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE1 DRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE1 RNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISD
370 380 390 400 410 420
410 420 430
pF1KE1 TMVAQLVQRLQRYSLSGGGTSSH
:::::::::::::::::::::::
NP_003 TMVAQLVQRLQRYSLSGGGTSSH
430 440
>>XP_016876283 (OMIM: 604984) PREDICTED: serine/threonin (517 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 1213.7 bits: 233.9 E(85289): 7.3e-61
Smith-Waterman score: 2744; 99.8% identity (100.0% similar) in 418 aa overlap (14-431:100-517)
10 20 30 40
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGID
.:::::::::::::::::::::::::::::
XP_016 QAGGRPGQGGDGERAWTRPGPSGVGRVEWRKNLKADPEELFTKLEKIGKGSFGEVFKGID
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE1 NRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLG
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE1 GGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADF
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE1 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELH
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE1 PMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSY
310 320 330 340 350 360
290 300 310 320 330 340
pF1KE1 LTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQ
370 380 390 400 410 420
350 360 370 380 390 400
pF1KE1 PSDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEAC
430 440 450 460 470 480
410 420 430
pF1KE1 PGISDTMVAQLVQRLQRYSLSGGGTSSH
::::::::::::::::::::::::::::
XP_016 PGISDTMVAQLVQRLQRYSLSGGGTSSH
490 500 510
>>XP_016876284 (OMIM: 604984) PREDICTED: serine/threonin (474 aa)
initn: 2742 init1: 2742 opt: 2742 Z-score: 1213.2 bits: 233.7 E(85289): 7.7e-61
Smith-Waterman score: 2742; 100.0% identity (100.0% similar) in 417 aa overlap (15-431:58-474)
10 20 30 40
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDN
::::::::::::::::::::::::::::::
XP_016 LIVTRERYKLGERKEPFLEESAFEQFLKVLNLKADPEELFTKLEKIGKGSFGEVFKGIDN
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE1 RTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGG
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE1 GSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFG
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE1 VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHP
210 220 230 240 250 260
230 240 250 260 270 280
pF1KE1 MKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYL
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE1 TELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQP
330 340 350 360 370 380
350 360 370 380 390 400
pF1KE1 SDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACP
390 400 410 420 430 440
410 420 430
pF1KE1 GISDTMVAQLVQRLQRYSLSGGGTSSH
:::::::::::::::::::::::::::
XP_016 GISDTMVAQLVQRLQRYSLSGGGTSSH
450 460 470
>>XP_005254136 (OMIM: 604984) PREDICTED: serine/threonin (333 aa)
initn: 2203 init1: 2203 opt: 2203 Z-score: 983.1 bits: 190.6 E(85289): 5.1e-48
Smith-Waterman score: 2203; 100.0% identity (100.0% similar) in 333 aa overlap (99-431:1-333)
70 80 90 100 110 120
pF1KE1 QEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREI
::::::::::::::::::::::::::::::
XP_005 MEYLGGGSALDLLEPGPLDETQIATILREI
10 20 30
130 140 150 160 170 180
pF1KE1 LKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAP
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 EVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 EFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDS
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 DAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPFSQCLSTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPFSQCLSTII
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 SPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGT
280 290 300 310 320 330
430
pF1KE1 SSH
:::
XP_005 SSH
>>NP_001273578 (OMIM: 604984) serine/threonine-protein k (412 aa)
initn: 2700 init1: 2125 opt: 2128 Z-score: 950.0 bits: 184.8 E(85289): 3.6e-46
Smith-Waterman score: 2666; 95.6% identity (95.6% similar) in 431 aa overlap (1-431:1-412)
10 20 30 40 50 60
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
::::::::::::::::::::::::::::::: ::::::::::
NP_001 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLK-------------------LEPGPLDETQ
70 80 90 100
130 140 150 160 170 180
pF1KE1 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE1 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE1 DDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE1 SQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQR
350 360 370 380 390 400
430
pF1KE1 YSLSGGGTSSH
:::::::::::
NP_001 YSLSGGGTSSH
410
>>NP_001258907 (OMIM: 602255) serine/threonine-protein k (426 aa)
initn: 1958 init1: 1712 opt: 2010 Z-score: 899.1 bits: 175.4 E(85289): 2.4e-43
Smith-Waterman score: 2010; 74.3% identity (90.5% similar) in 412 aa overlap (14-422:10-416)
10 20 30 40 50 60
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
:. ..:::::::::..:::::::::.:::::.:..::::::::::::
NP_001 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEA
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
:::::::::::::::::::::.:.:.:::::.:::::::::::::::::::.::::.::
NP_001 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
::::::::::::::::::.:::::::::::::::.:.:::::::::::::::::::::::
NP_001 IATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
::::::::::::::::: :::::::::::::::.::::.:.::::.::::::::.:::::
NP_001 GTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
:..:::.::::::::::.: :::::::::::::: : .::::.::::::::::::.:
NP_001 GQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWKSEGHG
240 250 260 270 280 290
310 320 330 340 350
pF1KE1 DDSSSEDSDAETDGQASGGSDSGDWIF--TIREKDPKNLENG-ALQPSDLDRNKMKDIPK
..::::::: ::.: : .. : : ::: . ..:..: ::. : .. . . .
NP_001 EESSSEDSDI--DGEAEDGEQGPIWTFPPTIRPSPHSKLHKGTALHSS---QKPAEPVKR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 RPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQR
.: ::::::.. :.:.::::: . ::..:..:::..:. ::::.:::::: ....::.:
NP_001 QPRSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVER
360 370 380 390 400 410
420 430
pF1KE1 LQRYSLSGGGTSSH
.::.:
NP_001 VQRFSHNRNHLTSTR
420
>>NP_006365 (OMIM: 602255) serine/threonine-protein kina (426 aa)
initn: 1958 init1: 1712 opt: 2010 Z-score: 899.1 bits: 175.4 E(85289): 2.4e-43
Smith-Waterman score: 2010; 74.3% identity (90.5% similar) in 412 aa overlap (14-422:10-416)
10 20 30 40 50 60
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
:. ..:::::::::..:::::::::.:::::.:..::::::::::::
NP_006 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEA
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
:::::::::::::::::::::.:.:.:::::.:::::::::::::::::::.::::.::
NP_006 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
::::::::::::::::::.:::::::::::::::.:.:::::::::::::::::::::::
NP_006 IATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
::::::::::::::::: :::::::::::::::.::::.:.::::.::::::::.:::::
NP_006 GTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
:..:::.::::::::::.: :::::::::::::: : .::::.::::::::::::.:
NP_006 GQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWKSEGHG
240 250 260 270 280 290
310 320 330 340 350
pF1KE1 DDSSSEDSDAETDGQASGGSDSGDWIF--TIREKDPKNLENG-ALQPSDLDRNKMKDIPK
..::::::: ::.: : .. : : ::: . ..:..: ::. : .. . . .
NP_006 EESSSEDSDI--DGEAEDGEQGPIWTFPPTIRPSPHSKLHKGTALHSS---QKPAEPVKR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 RPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQR
.: ::::::.. :.:.::::: . ::..:..:::..:. ::::.:::::: ....::.:
NP_006 QPRSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVER
360 370 380 390 400 410
420 430
pF1KE1 LQRYSLSGGGTSSH
.::.:
NP_006 VQRFSHNRNHLTSTR
420
>>NP_001258906 (OMIM: 602255) serine/threonine-protein k (426 aa)
initn: 1958 init1: 1712 opt: 2010 Z-score: 899.1 bits: 175.4 E(85289): 2.4e-43
Smith-Waterman score: 2010; 74.3% identity (90.5% similar) in 412 aa overlap (14-422:10-416)
10 20 30 40 50 60
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
:. ..:::::::::..:::::::::.:::::.:..::::::::::::
NP_001 MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEA
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
:::::::::::::::::::::.:.:.:::::.:::::::::::::::::::.::::.::
NP_001 EDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE1 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
::::::::::::::::::.:::::::::::::::.:.:::::::::::::::::::::::
NP_001 IATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE1 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
::::::::::::::::: :::::::::::::::.::::.:.::::.::::::::.:::::
NP_001 GTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE1 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSH
:..:::.::::::::::.: :::::::::::::: : .::::.::::::::::::.:
NP_001 GQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWKSEGHG
240 250 260 270 280 290
310 320 330 340 350
pF1KE1 DDSSSEDSDAETDGQASGGSDSGDWIF--TIREKDPKNLENG-ALQPSDLDRNKMKDIPK
..::::::: ::.: : .. : : ::: . ..:..: ::. : .. . . .
NP_001 EESSSEDSDI--DGEAEDGEQGPIWTFPPTIRPSPHSKLHKGTALHSS---QKPAEPVKR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 RPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQR
.: ::::::.. :.:.::::: . ::..:..:::..:. ::::.:::::: ....::.:
NP_001 QPRSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVER
360 370 380 390 400 410
420 430
pF1KE1 LQRYSLSGGGTSSH
.::.:
NP_001 VQRFSHNRNHLTSTR
420
>>NP_057626 (OMIM: 300547) serine/threonine-protein kina (416 aa)
initn: 1993 init1: 1755 opt: 1833 Z-score: 823.2 bits: 161.3 E(85289): 4.1e-39
Smith-Waterman score: 1990; 72.9% identity (88.0% similar) in 425 aa overlap (1-422:1-411)
10 20 30 40 50 60
pF1KE1 MAHSPVQSGLPGMQNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEA
:::::: .::::: :::::::::::.::::::::::::::::::.::::::::::::
NP_057 MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 EDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQ
::::::::::::::::::: ::::::::::: .::::::::::::::::::. ::.:: :
NP_057 EDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFV
:::.:.::::::::::::::::::::::::::::.:.:::::::::::::::::::::::
NP_057 IATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE
:::::::::::.:::::::::::::::::::::.::::.:..:::.:::::::::::::
NP_057 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLV
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAE-QS
:...: .:::..:::::.::::::::::::::::..:.::::::::::::.:::::: .:
NP_057 GDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE1 HDDSSSEDSDAETDGQASGGSDSGDWIFT-IREK-DPKNLENGALQPSDLDRNKMKDIPK
:.:.:: ::.:. .. . . .: :: .:.: :::...::: : :: .. .
NP_057 DDESDSEGSDSESTSREN--NTHPEWSFTTVRKKPDPKKVQNGAEQ--DL----VQTL--
310 320 330 340 350
360 370 380 390 400 410
pF1KE1 RPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQR
.::: ::.: :::::.... .. .::::. .: .:: :::::.: :: .:...
NP_057 ----SCLSMIITPAFAELKQQDENNASRNQAIEELEKSIAVAEAACPGITDKMVKKLIEK
360 370 380 390 400
420 430
pF1KE1 LQRYSLSGGGTSSH
.:. :
NP_057 FQKCSADESP
410
431 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:51:24 2016 done: Sun Nov 6 23:51:25 2016
Total Scan time: 7.610 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]