Result of FASTA (omim) for
pFN21AE1312
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1312, 480 aa
1>>>pF1KE1312 480 - 480 aa - 480 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1354+/-0.000444; mu= 14.4029+/- 0.028
mean_var=92.3974+/-18.810, 0's: 0 Z-trim(111.4): 96 B-trim: 678 in 1/54
Lambda= 0.133427
statistics sampled from 19834 (19933) to 19834 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.234), width: 16
Scan time: 8.580
The best scores are: opt bits E(85289)
XP_016860679 (OMIM: 603599) PREDICTED: CASP8 and F ( 480) 3169 620.7 2.8e-177
XP_016860680 (OMIM: 603599) PREDICTED: CASP8 and F ( 480) 3169 620.7 2.8e-177
NP_001120655 (OMIM: 603599) CASP8 and FADD-like ap ( 480) 3169 620.7 2.8e-177
NP_003870 (OMIM: 603599) CASP8 and FADD-like apopt ( 480) 3169 620.7 2.8e-177
XP_016860681 (OMIM: 603599) PREDICTED: CASP8 and F ( 462) 2864 562.0 1.3e-159
XP_016860682 (OMIM: 603599) PREDICTED: CASP8 and F ( 462) 2864 562.0 1.3e-159
XP_016860683 (OMIM: 603599) PREDICTED: CASP8 and F ( 462) 2864 562.0 1.3e-159
NP_001294971 (OMIM: 603599) CASP8 and FADD-like ap ( 462) 2864 562.0 1.3e-159
XP_016860678 (OMIM: 603599) PREDICTED: CASP8 and F ( 480) 2857 560.6 3.3e-159
XP_016860684 (OMIM: 603599) PREDICTED: CASP8 and F ( 384) 2556 502.6 7.7e-142
NP_001189446 (OMIM: 603599) CASP8 and FADD-like ap ( 384) 2556 502.6 7.7e-142
NP_001189447 (OMIM: 603599) CASP8 and FADD-like ap ( 366) 2251 443.9 3.5e-124
NP_001189448 (OMIM: 603599) CASP8 and FADD-like ap ( 366) 2251 443.9 3.5e-124
NP_001189445 (OMIM: 603599) CASP8 and FADD-like ap ( 445) 1678 333.7 6.6e-91
NP_001189444 (OMIM: 603599) CASP8 and FADD-like ap ( 235) 1608 320.0 4.4e-87
XP_016860685 (OMIM: 603599) PREDICTED: CASP8 and F ( 235) 1608 320.0 4.4e-87
XP_016860687 (OMIM: 603599) PREDICTED: CASP8 and F ( 221) 1285 257.8 2.2e-68
NP_001120656 (OMIM: 603599) CASP8 and FADD-like ap ( 221) 1285 257.8 2.2e-68
XP_016860686 (OMIM: 603599) PREDICTED: CASP8 and F ( 221) 1285 257.8 2.2e-68
NP_001294972 (OMIM: 603599) CASP8 and FADD-like ap ( 250) 1107 223.6 5e-58
XP_005246945 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
XP_006712853 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
XP_005246946 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
XP_006712852 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
NP_203519 (OMIM: 114480,114550,211980,601763,60727 ( 479) 411 89.8 1.8e-17
XP_005246947 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
XP_005246948 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
XP_005246943 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
XP_005246944 (OMIM: 114480,114550,211980,601763,60 ( 479) 411 89.8 1.8e-17
NP_001073594 (OMIM: 114480,114550,211980,601763,60 ( 538) 411 89.8 2e-17
XP_005246951 (OMIM: 114480,114550,211980,601763,60 ( 280) 281 64.6 4e-10
XP_011510271 (OMIM: 114480,114550,211980,601763,60 ( 334) 281 64.7 4.6e-10
XP_005246952 (OMIM: 114480,114550,211980,601763,60 ( 279) 249 58.5 2.9e-08
XP_006712859 (OMIM: 601762,603909,605027,613659) P ( 272) 244 57.5 5.5e-08
NP_203520 (OMIM: 114480,114550,211980,601763,60727 ( 464) 244 57.6 8.5e-08
XP_005246949 (OMIM: 114480,114550,211980,601763,60 ( 464) 244 57.6 8.5e-08
NP_001073593 (OMIM: 114480,114550,211980,601763,60 ( 464) 244 57.6 8.5e-08
XP_005246942 (OMIM: 114480,114550,211980,601763,60 ( 523) 244 57.7 9.3e-08
NP_203522 (OMIM: 114480,114550,211980,601763,60727 ( 235) 239 56.5 9.4e-08
XP_006712856 (OMIM: 114480,114550,211980,601763,60 ( 235) 239 56.5 9.4e-08
XP_005246950 (OMIM: 114480,114550,211980,601763,60 ( 294) 239 56.6 1.1e-07
NP_116764 (OMIM: 600639) caspase-2 isoform 1 prepr ( 452) 211 51.3 6.8e-06
NP_001215 (OMIM: 600639) caspase-2 isoform 2 [Homo ( 312) 202 49.5 1.7e-05
XP_011510292 (OMIM: 601762,603909,605027,613659) P ( 272) 201 49.2 1.7e-05
XP_011538562 (OMIM: 601761) PREDICTED: caspase-7 i ( 270) 199 48.8 2.2e-05
NP_001253987 (OMIM: 601761) caspase-7 isoform f [H ( 278) 199 48.8 2.3e-05
NP_001253985 (OMIM: 601761) caspase-7 isoform alph ( 303) 199 48.9 2.4e-05
NP_001218 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 199 48.9 2.4e-05
NP_203125 (OMIM: 601761) caspase-7 isoform alpha p ( 303) 199 48.9 2.4e-05
NP_001307840 (OMIM: 601761) caspase-7 isoform g [H ( 311) 199 48.9 2.5e-05
>>XP_016860679 (OMIM: 603599) PREDICTED: CASP8 and FADD- (480 aa)
initn: 3169 init1: 3169 opt: 3169 Z-score: 3303.7 bits: 620.7 E(85289): 2.8e-177
Smith-Waterman score: 3169; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
430 440 450 460 470 480
>>XP_016860680 (OMIM: 603599) PREDICTED: CASP8 and FADD- (480 aa)
initn: 3169 init1: 3169 opt: 3169 Z-score: 3303.7 bits: 620.7 E(85289): 2.8e-177
Smith-Waterman score: 3169; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
430 440 450 460 470 480
>>NP_001120655 (OMIM: 603599) CASP8 and FADD-like apopto (480 aa)
initn: 3169 init1: 3169 opt: 3169 Z-score: 3303.7 bits: 620.7 E(85289): 2.8e-177
Smith-Waterman score: 3169; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
430 440 450 460 470 480
>>NP_003870 (OMIM: 603599) CASP8 and FADD-like apoptosis (480 aa)
initn: 3169 init1: 3169 opt: 3169 Z-score: 3303.7 bits: 620.7 E(85289): 2.8e-177
Smith-Waterman score: 3169; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
430 440 450 460 470 480
>>XP_016860681 (OMIM: 603599) PREDICTED: CASP8 and FADD- (462 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 2986.7 bits: 562.0 E(85289): 1.3e-159
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
:::::::::::::::
XP_016 SLYLQCLSQKLRQERGTIPGSGITESKDMHFSSLGCILLDVL
430 440 450 460
>>XP_016860682 (OMIM: 603599) PREDICTED: CASP8 and FADD- (462 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 2986.7 bits: 562.0 E(85289): 1.3e-159
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
:::::::::::::::
XP_016 SLYLQCLSQKLRQERGTIPGSGITESKDMHFSSLGCILLDVL
430 440 450 460
>>XP_016860683 (OMIM: 603599) PREDICTED: CASP8 and FADD- (462 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 2986.7 bits: 562.0 E(85289): 1.3e-159
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
:::::::::::::::
XP_016 SLYLQCLSQKLRQERGTIPGSGITESKDMHFSSLGCILLDVL
430 440 450 460
>>NP_001294971 (OMIM: 603599) CASP8 and FADD-like apopto (462 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 2986.7 bits: 562.0 E(85289): 1.3e-159
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
:::::::::::::::
NP_001 SLYLQCLSQKLRQERGTIPGSGITESKDMHFSSLGCILLDVL
430 440 450 460
>>XP_016860678 (OMIM: 603599) PREDICTED: CASP8 and FADD- (480 aa)
initn: 2857 init1: 2857 opt: 2857 Z-score: 2979.2 bits: 560.6 E(85289): 3.3e-159
Smith-Waterman score: 2857; 100.0% identity (100.0% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::
XP_016 SLYLQCLSQKLRQESSFTAKAGDKDCFSFSAFSFSEGGQFPEVELQSQRTCIFQASDASY
430 440 450 460 470 480
>>XP_016860684 (OMIM: 603599) PREDICTED: CASP8 and FADD- (384 aa)
initn: 2556 init1: 2556 opt: 2556 Z-score: 2667.4 bits: 502.6 E(85289): 7.7e-142
Smith-Waterman score: 2556; 100.0% identity (100.0% similar) in 384 aa overlap (97-480:1-384)
70 80 90 100 110 120
pF1KE1 LLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKIS
::::::::::::::::::::::::::::::
XP_016 MAEIGEDLDKSDVSSLIFLMKDYMGRGKIS
10 20 30
130 140 150 160 170 180
pF1KE1 KEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 QAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKM
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 KSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 LEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQC
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 LSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
340 350 360 370 380
480 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:28:24 2016 done: Sun Nov 6 23:28:26 2016
Total Scan time: 8.580 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]