Result of FASTA (ccds) for
pFN21AE1312
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1312, 480 aa
1>>>pF1KE1312 480 - 480 aa - 480 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2940+/-0.00106; mu= 13.1978+/- 0.063
mean_var=86.9420+/-17.125, 0's: 0 Z-trim(104.4): 47 B-trim: 0 in 0/54
Lambda= 0.137550
statistics sampled from 7847 (7892) to 7847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.242), width: 16
Scan time: 2.380
The best scores are: opt bits E(32554)
CCDS2337.1 CFLAR gene_id:8837|Hs108|chr2 ( 480) 3169 639.2 2.8e-183
CCDS77505.1 CFLAR gene_id:8837|Hs108|chr2 ( 462) 2864 578.7 4.5e-165
CCDS56158.1 CFLAR gene_id:8837|Hs108|chr2 ( 384) 2556 517.5 9.6e-147
CCDS59436.1 CFLAR gene_id:8837|Hs108|chr2 ( 366) 2251 457.0 1.5e-128
CCDS56157.1 CFLAR gene_id:8837|Hs108|chr2 ( 445) 1678 343.3 3.1e-94
CCDS46487.1 CFLAR gene_id:8837|Hs108|chr2 ( 221) 1285 265.2 5e-71
CCDS77503.1 CFLAR gene_id:8837|Hs108|chr2 ( 250) 1107 229.9 2.4e-60
CCDS2342.1 CASP8 gene_id:841|Hs108|chr2 ( 479) 411 91.9 1.6e-18
CCDS42798.1 CASP8 gene_id:841|Hs108|chr2 ( 538) 411 91.9 1.8e-18
>>CCDS2337.1 CFLAR gene_id:8837|Hs108|chr2 (480 aa)
initn: 3169 init1: 3169 opt: 3169 Z-score: 3403.9 bits: 639.2 E(32554): 2.8e-183
Smith-Waterman score: 3169; 100.0% identity (100.0% similar) in 480 aa overlap (1-480:1-480)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
430 440 450 460 470 480
>>CCDS77505.1 CFLAR gene_id:8837|Hs108|chr2 (462 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 3077.0 bits: 578.7 E(32554): 4.5e-165
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
:::::::::::::::
CCDS77 SLYLQCLSQKLRQERGTIPGSGITESKDMHFSSLGCILLDVL
430 440 450 460
>>CCDS56158.1 CFLAR gene_id:8837|Hs108|chr2 (384 aa)
initn: 2556 init1: 2556 opt: 2556 Z-score: 2748.0 bits: 517.5 E(32554): 9.6e-147
Smith-Waterman score: 2556; 100.0% identity (100.0% similar) in 384 aa overlap (97-480:1-384)
70 80 90 100 110 120
pF1KE1 LLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKIS
::::::::::::::::::::::::::::::
CCDS56 MAEIGEDLDKSDVSSLIFLMKDYMGRGKIS
10 20 30
130 140 150 160 170 180
pF1KE1 KEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 QAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKM
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 KSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 LEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQC
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 LSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
340 350 360 370 380
>>CCDS59436.1 CFLAR gene_id:8837|Hs108|chr2 (366 aa)
initn: 2251 init1: 2251 opt: 2251 Z-score: 2421.2 bits: 457.0 E(32554): 1.5e-128
Smith-Waterman score: 2251; 100.0% identity (100.0% similar) in 339 aa overlap (97-435:1-339)
70 80 90 100 110 120
pF1KE1 LLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKIS
::::::::::::::::::::::::::::::
CCDS59 MAEIGEDLDKSDVSSLIFLMKDYMGRGKIS
10 20 30
130 140 150 160 170 180
pF1KE1 KEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 KEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVL
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE1 QAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 QAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKM
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE1 KSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 KSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE1 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE1 LEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQC
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE1 LSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
:::::::::
CCDS59 LSQKLRQERGTIPGSGITESKDMHFSSLGCILLDVL
340 350 360
>>CCDS56157.1 CFLAR gene_id:8837|Hs108|chr2 (445 aa)
initn: 1662 init1: 1662 opt: 1678 Z-score: 1805.3 bits: 343.3 E(32554): 3.1e-94
Smith-Waterman score: 2863; 92.7% identity (92.7% similar) in 480 aa overlap (1-480:1-445)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
:::::::::::::::::::::: :::
CCDS56 SYRNVLQAAIQKSLKDPSNNFR-----------------------------------SIP
190 200
250 260 270 280 290 300
pF1KE1 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMP
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNY
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE1 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 VVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSP
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE1 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
390 400 410 420 430 440
>>CCDS46487.1 CFLAR gene_id:8837|Hs108|chr2 (221 aa)
initn: 1285 init1: 1285 opt: 1285 Z-score: 1388.6 bits: 265.2 E(32554): 5e-71
Smith-Waterman score: 1285; 99.5% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
::::::::::::::::::::::.
CCDS46 SYRNVLQAAIQKSLKDPSNNFRMITPYAHCPDLKILGNCSM
190 200 210 220
>>CCDS77503.1 CFLAR gene_id:8837|Hs108|chr2 (250 aa)
initn: 1139 init1: 1107 opt: 1107 Z-score: 1196.8 bits: 229.9 E(32554): 2.4e-60
Smith-Waterman score: 1107; 97.8% identity (97.8% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
:::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS77 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSGGWNGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIP
CCDS77 WMTKASFSLWLEIASLYILHIPDLPTPLPCIFMISAKCCQAVLNISVFKKESGICTGWQS
190 200 210 220 230 240
>>CCDS2342.1 CASP8 gene_id:841|Hs108|chr2 (479 aa)
initn: 338 init1: 158 opt: 411 Z-score: 446.0 bits: 91.9 E(32554): 1.6e-18
Smith-Waterman score: 498; 26.9% identity (58.1% similar) in 506 aa overlap (6-477:7-476)
10 20 30 40 50
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRD---LLDILRERGKLSVGDLA
.... : ::... : :: : . ..: :.. :.:. : ..:.
CCDS23 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ---ELLYRVRRFDLLKRILKMDRKAVETHLLRNPH--LVSDYRVLMAEIGEDLDKSDVSS
:::.:. :.::: :. .. .: .: ..: .: :::.. .:.:....:.. :
CCDS23 FLKELLFRINRLDLLITYLNTRKEEMEREL-QTPGRAQISAYRVMLYQISEEVSRSELRS
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKY
. ::... ... :.. . ..::. .:.:: ... .::.:.. .:.. :: :. :
CCDS23 FKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQES
.. .. :. .::. ..: :: ..: . .. : . :.:
CCDS23 EEF-----SKERS-------SSLEGSPDEF--SNG----EELCGVMTISDSPRE---QDS
180 190 200 210
240 250 260 270
pF1KE1 EAFLPQSIPEERYKMKSKPLGICLIIDCIG-----------------NETEL----LRDT
:. :.. .. :.::::: : ::::. . : :.: : :
CCDS23 ES---QTL-DKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTT
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE1 FTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSG
: : .:.. ... : .:: . : .: ..: :.: ..:.: . .::.: ..
CCDS23 FEELHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMDCFICCILSHGDKGIIYGTDGQEA-
280 290 300 310 320 330
340 350 360 370 380
pF1KE1 LPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSL-LEVDGPAMKNVEFKAQK
:.... .: : .:: ::::::.:::: . .:. .... .:.:. . .:. ..
CCDS23 -PIYELTSQFTGLKCPSLAGKPKVFFIQ---ACQGDNYQKGIPVETDSEEQPYLEMDLSS
340 350 360 370 380
390 400 410 420 430 440
pF1KE1 RGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQE--RKRPLLDLHIELN
. ::::. .. :.. . .. . . :.: : :.::.. : .: . :.:
CCDS23 PQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVN
390 400 410 420 430 440
450 460 470 480
pF1KE1 GYMYDWNSRVSAKE--KYYVWLQHTLRKKLILSYT
:. ... . :. : . ::::::..
CCDS23 ---YEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
450 460 470
>>CCDS42798.1 CASP8 gene_id:841|Hs108|chr2 (538 aa)
initn: 338 init1: 158 opt: 411 Z-score: 445.2 bits: 91.9 E(32554): 1.8e-18
Smith-Waterman score: 498; 26.9% identity (58.1% similar) in 506 aa overlap (6-477:66-535)
10 20 30
pF1KE1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPP
.... : ::... : :: : .
CCDS42 LGDSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQE
40 50 60 70 80 90
40 50 60 70 80
pF1KE1 NVRD---LLDILRERGKLSVGDLA---ELLYRVRRFDLLKRILKMDRKAVETHLLRNPH-
..: :.. :.:. : ..:. :::.:. :.::: :. .. .: .: ..:
CCDS42 PIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMEREL-QTPGR
100 110 120 130 140 150
90 100 110 120 130 140
pF1KE1 -LVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPD
.: :::.. .:.:....:.. :. ::... ... :.. . ..::. .:.:: ...
CCDS42 AQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEG
160 170 180 190 200 210
150 160 170 180 190 200
pF1KE1 QLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGR
.::.:.. .:.. :: :. :.. .. :. .::. ..: ::
CCDS42 KLDILKRVCAQINKSLLKI-INDYEEF-----SKERS-------SSLEGSPDEF--SNG-
220 230 240 250
210 220 230 240 250 260
pF1KE1 SKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIG------
..: . .. : . :.::. :.. .. :.::::: : ::::. .
CCDS42 ---EELCGVMTISDSPRE---QDSES---QTL-DKVYQMKSKPRGYCLIINNHNFAKARE
260 270 280 290 300
270 280 290 300
pF1KE1 -----------NETEL----LRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYD
: :.: : :: : .:.. ... : .:: . : .: ..:
CCDS42 KVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLM-DHSNMD
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE1 SFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ
:.: ..:.: . .::.: .. :.... .: : .:: ::::::.:::: . .:.
CCDS42 CFICCILSHGDKGIIYGTDGQEA--PIYELTSQFTGLKCPSLAGKPKVFFIQ---ACQGD
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE1 LEDSSL-LEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQ
.... .:.:. . .:. .. . ::::. .. :.. . .. . . :.:
CCDS42 NYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQ
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE1 CLSQKLRQE--RKRPLLDLHIELNGYMYDWNSRVSAKE--KYYVWLQHTLRKKLILSYT
: :.::.. : .: . :.: :. ... . :. : . ::::::..
CCDS42 SLCQSLRERCPRGDDILTILTEVN---YEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
490 500 510 520 530
480 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:28:24 2016 done: Sun Nov 6 23:28:24 2016
Total Scan time: 2.380 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]