Result of FASTA (omim) for
pFN21AE1273
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1273, 696 aa
1>>>pF1KE1273 696 - 696 aa - 696 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.3807+/-0.00051; mu= -21.4482+/- 0.032
mean_var=628.5333+/-128.957, 0's: 0 Z-trim(121.1): 81 B-trim: 0 in 0/59
Lambda= 0.051158
statistics sampled from 38807 (38888) to 38807 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.416), width: 16
Scan time: 6.360
The best scores are: opt bits E(93482)
NP_055313 (OMIM: 606805) Golgi integral membrane p ( 696) 4608 355.7 3.8e-97
XP_005247421 (OMIM: 606805) Golgi integral membran ( 697) 4596 354.8 7e-97
NP_001295084 (OMIM: 606805) Golgi integral membran ( 668) 3225 253.6 1.9e-66
XP_024309223 (OMIM: 606805) Golgi integral membran ( 549) 3213 252.7 3.1e-66
XP_005247422 (OMIM: 606805) Golgi integral membran ( 669) 3213 252.7 3.6e-66
XP_016861672 (OMIM: 606805) Golgi integral membran ( 550) 3201 251.8 5.8e-66
NP_009044 (OMIM: 190370,617252) trichohyalin [Homo (1943) 377 43.8 0.0081
>>NP_055313 (OMIM: 606805) Golgi integral membrane prote (696 aa)
initn: 4608 init1: 4608 opt: 4608 Z-score: 1865.9 bits: 355.7 E(93482): 3.8e-97
Smith-Waterman score: 4608; 100.0% identity (100.0% similar) in 696 aa overlap (1-696:1-696)
10 20 30 40 50 60
pF1KE1 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 AHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 DRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEV
610 620 630 640 650 660
670 680 690
pF1KE1 RDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
::::::::::::::::::::::::::::::::::::
NP_055 RDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
670 680 690
>>XP_005247421 (OMIM: 606805) Golgi integral membrane pr (697 aa)
initn: 3469 init1: 3392 opt: 4596 Z-score: 1861.1 bits: 354.8 E(93482): 7e-97
Smith-Waterman score: 4596; 99.9% identity (99.9% similar) in 697 aa overlap (1-696:1-697)
10 20 30 40 50 60
pF1KE1 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
430 440 450 460 470 480
490 500 510 520 530
pF1KE1 AHYDAMDNDIVQGAEDQGIQGEEG-AYERDNQHQDEAEGDPGNRHEPREQGPREADPESE
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_005 AHYDAMDNDIVQGAEDQGIQGEEGGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE1 ADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE1 GNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQE
610 620 630 640 650 660
660 670 680 690
pF1KE1 VRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
:::::::::::::::::::::::::::::::::::::
XP_005 VRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
670 680 690
>>NP_001295084 (OMIM: 606805) Golgi integral membrane pr (668 aa)
initn: 3178 init1: 3178 opt: 3225 Z-score: 1314.5 bits: 253.6 E(93482): 1.9e-66
Smith-Waterman score: 4369; 96.0% identity (96.0% similar) in 696 aa overlap (1-696:1-668)
10 20 30 40 50 60
pF1KE1 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
:::::::::::::::::::: ::::::::::::
NP_001 ENRQLRKAHQDIHTQLQDVK----------------------------TQVAEYKQLKDT
190 200 210
250 260 270 280 290 300
pF1KE1 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 AHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 DRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAG
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEV
580 590 600 610 620 630
670 680 690
pF1KE1 RDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
::::::::::::::::::::::::::::::::::::
NP_001 RDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
640 650 660
>>XP_024309223 (OMIM: 606805) Golgi integral membrane pr (549 aa)
initn: 3178 init1: 3178 opt: 3213 Z-score: 1310.8 bits: 252.7 E(93482): 3.1e-66
Smith-Waterman score: 3613; 95.1% identity (95.1% similar) in 577 aa overlap (120-696:1-549)
90 100 110 120 130 140
pF1KE1 LVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRT
::::::::::::::::::::::::::::::
XP_024 MLKSQHEELKKQHSDLEEEHRKQGEDFSRT
10 20 30
150 160 170 180 190 200
pF1KE1 FNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVK---------
40 50 60 70 80
210 220 230 240 250 260
pF1KE1 HEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYN
:::::::::::::::::::::::::::::::::::::::::
XP_024 -------------------TQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYN
90 100 110 120
270 280 290 300 310 320
pF1KE1 TAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 TAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERRE
130 140 150 160 170 180
330 340 350 360 370 380
pF1KE1 PEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHA
190 200 210 220 230 240
390 400 410 420 430 440
pF1KE1 RAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQ
250 260 270 280 290 300
450 460 470 480 490 500
pF1KE1 QQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 QQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERD
310 320 330 340 350 360
510 520 530 540 550 560
pF1KE1 NQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVR
370 380 390 400 410 420
570 580 590 600 610 620
pF1KE1 EENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 EENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEK
430 440 450 460 470 480
630 640 650 660 670 680
pF1KE1 KRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAEK
490 500 510 520 530 540
690
pF1KE1 SHRRAEM
:::::::
XP_024 SHRRAEM
>>XP_005247422 (OMIM: 606805) Golgi integral membrane pr (669 aa)
initn: 3442 init1: 1962 opt: 3213 Z-score: 1309.7 bits: 252.7 E(93482): 3.6e-66
Smith-Waterman score: 4357; 95.8% identity (95.8% similar) in 697 aa overlap (1-696:1-669)
10 20 30 40 50 60
pF1KE1 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNGMCSRKQKRIFQTLLLLTVVFGFLYGAMLYYELQTQLRKAEAVALKYQQHQESLSAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQVVYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLRE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDT
:::::::::::::::::::: ::::::::::::
XP_005 ENRQLRKAHQDIHTQLQDVK----------------------------TQVAEYKQLKDT
190 200 210
250 260 270 280 290 300
pF1KE1 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLEEE
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAELEEGRPQHQEQLRQQ
400 410 420 430 440 450
490 500 510 520 530
pF1KE1 AHYDAMDNDIVQGAEDQGIQGEEG-AYERDNQHQDEAEGDPGNRHEPREQGPREADPESE
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_005 AHYDAMDNDIVQGAEDQGIQGEEGGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESE
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE1 ADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMA
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE1 GNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQE
580 590 600 610 620 630
660 670 680 690
pF1KE1 VRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
:::::::::::::::::::::::::::::::::::::
XP_005 VRDDNRPKGREEHYEEEEEEEEDGAAVAEKSHRRAEM
640 650 660
>>XP_016861672 (OMIM: 606805) Golgi integral membrane pr (550 aa)
initn: 2686 init1: 1962 opt: 3201 Z-score: 1306.0 bits: 251.8 E(93482): 5.8e-66
Smith-Waterman score: 3601; 95.0% identity (95.0% similar) in 578 aa overlap (120-696:1-550)
90 100 110 120 130 140
pF1KE1 LVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRT
::::::::::::::::::::::::::::::
XP_016 MLKSQHEELKKQHSDLEEEHRKQGEDFSRT
10 20 30
150 160 170 180 190 200
pF1KE1 FNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQDVK---------
40 50 60 70 80
210 220 230 240 250 260
pF1KE1 HEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYN
:::::::::::::::::::::::::::::::::::::::::
XP_016 -------------------TQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYN
90 100 110 120
270 280 290 300 310 320
pF1KE1 TAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERRE
130 140 150 160 170 180
330 340 350 360 370 380
pF1KE1 PEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEHQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHA
190 200 210 220 230 240
390 400 410 420 430 440
pF1KE1 RAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQ
250 260 270 280 290 300
450 460 470 480 490 500
pF1KE1 QQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEG-AYER
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 QQQQVAREMALQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGGAYER
310 320 330 340 350 360
510 520 530 540 550 560
pF1KE1 DNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQV
370 380 390 400 410 420
570 580 590 600 610 620
pF1KE1 REENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEE
430 440 450 460 470 480
630 640 650 660 670 680
pF1KE1 KKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAE
490 500 510 520 530 540
690
pF1KE1 KSHRRAEM
::::::::
XP_016 KSHRRAEM
550
>>NP_009044 (OMIM: 190370,617252) trichohyalin [Homo sap (1943 aa)
initn: 617 init1: 168 opt: 377 Z-score: 172.3 bits: 43.8 E(93482): 0.0081
Smith-Waterman score: 426; 24.2% identity (59.2% similar) in 574 aa overlap (136-695:115-645)
110 120 130 140 150 160
pF1KE1 DSNSRYSALNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHK-QKYLQLQQEK
.:: ... : .: .... :. : .::.
NP_009 CYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ
90 100 110 120 130 140
170 180 190 200 210 220
pF1KE1 EQELSKLKE-TVYNLREENRQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSA
:.::.. .: . . : :.:. .. ... : :. :.... .:.::: . . :..
NP_009 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW-QEREERRAEEEQLQ-SCKGHETE
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE1 LAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVS
. :. . . :. ::. :.:. ::. : ::
NP_009 EFPDEEQLRRRELLE--------LRRKGREEKQQ------------QRRERQDRVFQE--
210 220 230 240
290 300 310 320 330 340
pF1KE1 RNNDVWQNHEAVPGRAEDTKLYAPT-HKEAEFQAPPEPIQQEVERRE-PEEHQVEEEHRK
... :...:.: : :. :: ... :.: : ... .::.: .:.: ::....
NP_009 EEEKEWRKRETVL-RKEEEKLQEEEPQRQRELQEEEEQLRK-LERQELRRERQEEEQQQQ
250 260 270 280 290
350 360 370 380 390 400
pF1KE1 ALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMI
:..:.. . : :. .:... :.:.: .::.:.:. : . : : . ..
NP_009 RLRREQQLRRKQEEERREQQEERREQQER--REQQEERR-----EQQLRREQEERREQQL
300 310 320 330 340 350
410 420 430 440 450
pF1KE1 KFQSPYEEQLEQQRLAVQQVEE--AQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMA
. .. ::. ..:.: .: :: ::::..:. ..:.:. . :: ...::. ::.
NP_009 RREQ--EEERREQQLRREQEEERREQQLRREQQLRREQQLRRE---QQLRREQQLRREQQ
360 370 380 390 400
460 470 480 490 500 510
pF1KE1 LQRQAELE-EGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEG
:.:. .:. : . ....:::.. . . .. : ..: .. :. :: . . : :
NP_009 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ--EERRDWLKREEET
410 420 430 440 450 460
520 530 540 550 560 570
pF1KE1 DPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENE
. .... ..: :. . : . .:. . .. . . .. .: :. ::. : ..:
NP_009 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE
470 480 490 500 510 520
580 590 600 610 620 630
pF1KE1 EQK-----QSNQ--KQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKR
:.. .:.: ..:. : .:.:. . . :.. :: .. .:: ...: ::
NP_009 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL---KR
530 540 550 560 570 580
640 650 660 670 680 690
pF1KE1 ELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGAAVAEKSH
: :. .. :..: ... . : .......: . : .. : :::.... :. .
NP_009 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE
590 600 610 620 630 640
pF1KE1 RRAEM
:: .
NP_009 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI
650 660 670 680 690 700
696 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Jun 21 11:07:55 2019 done: Fri Jun 21 11:07:56 2019
Total Scan time: 6.360 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]