Result of FASTA (ccds) for
pFN21AE1263
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1263, 607 aa
1>>>pF1KE1263 607 - 607 aa - 607 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1610+/-0.00148; mu= -3.8906+/- 0.086
mean_var=314.8530+/-67.888, 0's: 0 Z-trim(106.8): 119 B-trim: 389 in 1/52
Lambda= 0.072280
statistics sampled from 9099 (9197) to 9099 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.283), width: 16
Scan time: 3.780
The best scores are: opt bits E(32554)
CCDS2503.2 ATG16L1 gene_id:55054|Hs108|chr2 ( 607) 3996 431.5 1.6e-120
CCDS2502.2 ATG16L1 gene_id:55054|Hs108|chr2 ( 588) 2165 240.5 4.6e-63
CCDS54438.1 ATG16L1 gene_id:55054|Hs108|chr2 ( 444) 2159 239.8 5.8e-63
CCDS31634.1 ATG16L2 gene_id:89849|Hs108|chr11 ( 619) 1059 125.2 2.5e-28
>>CCDS2503.2 ATG16L1 gene_id:55054|Hs108|chr2 (607 aa)
initn: 3996 init1: 3996 opt: 3996 Z-score: 2277.4 bits: 431.5 E(32554): 1.6e-120
Smith-Waterman score: 3996; 100.0% identity (100.0% similar) in 607 aa overlap (1-607:1-607)
10 20 30 40 50 60
pF1KE1 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 EVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 HPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 ARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 ARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSES
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 IVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 IVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCK
550 560 570 580 590 600
pF1KE1 AVLWAQY
:::::::
CCDS25 AVLWAQY
>>CCDS2502.2 ATG16L1 gene_id:55054|Hs108|chr2 (588 aa)
initn: 2158 init1: 2158 opt: 2165 Z-score: 1245.7 bits: 240.5 E(32554): 4.6e-63
Smith-Waterman score: 3826; 96.9% identity (96.9% similar) in 607 aa overlap (1-607:1-588)
10 20 30 40 50 60
pF1KE1 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDT
::::::::::::::::::::::::: ::::::::::::::::
CCDS25 EVIVDETSDHTEETSPVRAISRAAT-------------------RRSVSSFPVPQDNVDT
250 260 270 280
310 320 330 340 350 360
pF1KE1 HPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE1 SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDN
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE1 ARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 ARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSES
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE1 IVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 IVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRV
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE1 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCK
530 540 550 560 570 580
pF1KE1 AVLWAQY
:::::::
CCDS25 AVLWAQY
>>CCDS54438.1 ATG16L1 gene_id:55054|Hs108|chr2 (444 aa)
initn: 2600 init1: 2158 opt: 2159 Z-score: 1243.9 bits: 239.8 E(32554): 5.8e-63
Smith-Waterman score: 2591; 73.1% identity (73.1% similar) in 607 aa overlap (1-607:1-444)
10 20 30 40 50 60
pF1KE1 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRK
:::::::::
CCDS54 HDVPNRHEI---------------------------------------------------
130 140 150 160 170 180
pF1KE1 DREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL
CCDS54 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE1 RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDI
:::::::::::::::::::::::::::
CCDS54 ---------------------------------RRRQARLQKELAEAAKEPLPVEQDDDI
70 80 90
250 260 270 280 290 300
pF1KE1 EVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDT
::::::::::::::::::::::::: ::::::::::::::::
CCDS54 EVIVDETSDHTEETSPVRAISRAAT-------------------RRSVSSFPVPQDNVDT
100 110 120 130
310 320 330 340 350 360
pF1KE1 HPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG
140 150 160 170 180 190
370 380 390 400 410 420
pF1KE1 SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDN
200 210 220 230 240 250
430 440 450 460 470 480
pF1KE1 ARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSES
260 270 280 290 300 310
490 500 510 520 530 540
pF1KE1 IVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRV
320 330 340 350 360 370
550 560 570 580 590 600
pF1KE1 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCK
380 390 400 410 420 430
pF1KE1 AVLWAQY
:::::::
CCDS54 AVLWAQY
440
>>CCDS31634.1 ATG16L2 gene_id:89849|Hs108|chr11 (619 aa)
initn: 1445 init1: 1025 opt: 1059 Z-score: 622.1 bits: 125.2 E(32554): 2.5e-28
Smith-Waterman score: 1411; 38.8% identity (67.2% similar) in 616 aa overlap (4-604:5-618)
10 20 30 40 50
pF1KE1 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAE
:. .: :::::: .::: ::: :. : :.. ::.::::..: . ...::: :
CCDS31 MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KHDV-PNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQ
..: :. :. .: ... ...:. .. ::.: ::: :. ::.: :.. . .
CCDS31 PNSVTPTTHQ-GPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALG
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 RKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEG
. :.:. ....: ...:. . .. . . : . . :.::. :.
CCDS31 TLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 KLRKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPV-EQD
::. :: ..:. : . .::. : . : .::. : .:::...:: .:::. . . :
CCDS31 ALRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGP
180 190 200 210 220 230
240 250 260 270 280
pF1KE1 DDIEVIVDETSDHTEETSPVRAISRAATKRLSQP-----AGGL-----LDSITNIFG---
: . . : . . . . . : .. ..: : .: .: . ...
CCDS31 DTLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 RRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDR
::. : .:.. . : .:.:. : :.::: .:::::.:.:.: :::::: ::
CCDS31 RRGHSIGGAPEQRYQIIP-VCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADR
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 RVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTL
..::.: : . : . .: :....:::..:: .: .:::. . :...: : . . ..::
CCDS31 LIHLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETL
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE1 TGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMS
.::. :: .::: : . :.::.:::.: ::: : .:. . : :::.:: .. ..:
CCDS31 SGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIIS
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE1 GHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQ
:: :.:::::: :. .. . . :..:.:.:. .. .:::::::. :::::::.. :.:
CCDS31 GHNDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQ
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE1 TFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVA
.: : :::::::::..::::: ::. ::: .:.::::.: :::.:. :. : ...::::
CCDS31 VFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVA
540 550 560 570 580 590
590 600
pF1KE1 WSPSGSHVVSVDKGCKAVLWAQY
: ::::.::::.: :.:::
CCDS31 WCYSGSHMVSVDQGRKVVLWQ
600 610
607 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:38:09 2016 done: Sun Nov 6 21:38:10 2016
Total Scan time: 3.780 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]