Result of FASTA (omim) for
pFN21AE1250
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1250, 506 aa
1>>>pF1KE1250 506 - 506 aa - 506 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.2514+/-0.00038; mu= -10.7762+/- 0.024
mean_var=510.1538+/-105.360, 0's: 0 Z-trim(125.4): 28 B-trim: 0 in 0/61
Lambda= 0.056784
statistics sampled from 48867 (48904) to 48867 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.573), width: 16
Scan time: 12.970
The best scores are: opt bits E(85289)
NP_001092267 (OMIM: 611163) TOX high mobility grou ( 506) 3423 294.7 4.4e-79
XP_006723947 (OMIM: 611163) PREDICTED: TOX high mo ( 515) 3196 276.1 1.8e-73
NP_001092266 (OMIM: 611163) TOX high mobility grou ( 464) 3127 270.4 8.2e-72
NP_116272 (OMIM: 611163) TOX high mobility group b ( 464) 3127 270.4 8.2e-72
NP_001092268 (OMIM: 611163) TOX high mobility grou ( 488) 1812 162.7 2.3e-39
XP_016883598 (OMIM: 611163) PREDICTED: TOX high mo ( 305) 1678 151.5 3.3e-36
XP_016869574 (OMIM: 606863) PREDICTED: thymocyte s ( 504) 907 88.5 4.8e-17
NP_055544 (OMIM: 606863) thymocyte selection-assoc ( 526) 906 88.5 5.3e-17
XP_011521304 (OMIM: 611416) PREDICTED: TOX high mo ( 553) 829 82.2 4.3e-15
NP_001139660 (OMIM: 611416) TOX high mobility grou ( 571) 829 82.2 4.4e-15
XP_016878631 (OMIM: 611416) PREDICTED: TOX high mo ( 572) 829 82.2 4.4e-15
XP_005255949 (OMIM: 611416) PREDICTED: TOX high mo ( 575) 829 82.2 4.5e-15
NP_001073899 (OMIM: 611416) TOX high mobility grou ( 576) 829 82.2 4.5e-15
NP_055643 (OMIM: 614032) TOX high mobility group b ( 621) 749 75.7 4.4e-13
NP_001290452 (OMIM: 614032) TOX high mobility grou ( 598) 724 73.6 1.8e-12
>>NP_001092267 (OMIM: 611163) TOX high mobility group bo (506 aa)
initn: 3423 init1: 3423 opt: 3423 Z-score: 1540.8 bits: 294.7 E(85289): 4.4e-79
Smith-Waterman score: 3423; 100.0% identity (100.0% similar) in 506 aa overlap (1-506:1-506)
10 20 30 40 50 60
pF1KE1 MDVRLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDVRLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GIRSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIRSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDW
430 440 450 460 470 480
490 500
pF1KE1 DSSYPSGECGISTCSLLPRDKSLYLT
::::::::::::::::::::::::::
NP_001 DSSYPSGECGISTCSLLPRDKSLYLT
490 500
>>XP_006723947 (OMIM: 611163) PREDICTED: TOX high mobili (515 aa)
initn: 3196 init1: 3196 opt: 3196 Z-score: 1440.2 bits: 276.1 E(85289): 1.8e-73
Smith-Waterman score: 3196; 100.0% identity (100.0% similar) in 474 aa overlap (33-506:42-515)
10 20 30 40 50 60
pF1KE1 VRLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQSE
::::::::::::::::::::::::::::::
XP_006 AFSRCLGFCGMRLGLLLLARHWCIAGVFPQKFDGDSAYVGMSDGNPELLSTSQTYNGQSE
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 NNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSN
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE1 MLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGI
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE1 RSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKD
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE1 PNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAA
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 KKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQ
320 330 340 350 360 370
370 380 390 400 410 420
pF1KE1 AFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVS
380 390 400 410 420 430
430 440 450 460 470 480
pF1KE1 MSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDS
440 450 460 470 480 490
490 500
pF1KE1 SYPSGECGISTCSLLPRDKSLYLT
::::::::::::::::::::::::
XP_006 SYPSGECGISTCSLLPRDKSLYLT
500 510
>>NP_001092266 (OMIM: 611163) TOX high mobility group bo (464 aa)
initn: 3127 init1: 3127 opt: 3127 Z-score: 1410.3 bits: 270.4 E(85289): 8.2e-72
Smith-Waterman score: 3127; 100.0% identity (100.0% similar) in 464 aa overlap (43-506:1-464)
20 30 40 50 60 70
pF1KE1 GARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQSENNEDYEIPPI
::::::::::::::::::::::::::::::
NP_001 MSDGNPELLSTSQTYNGQSENNEDYEIPPI
10 20 30
80 90 100 110 120 130
pF1KE1 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 GQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 YALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAA
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE1 YRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPAS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE1 LARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE1 PTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGIS
400 410 420 430 440 450
500
pF1KE1 TCSLLPRDKSLYLT
::::::::::::::
NP_001 TCSLLPRDKSLYLT
460
>>NP_116272 (OMIM: 611163) TOX high mobility group box f (464 aa)
initn: 3127 init1: 3127 opt: 3127 Z-score: 1410.3 bits: 270.4 E(85289): 8.2e-72
Smith-Waterman score: 3127; 100.0% identity (100.0% similar) in 464 aa overlap (43-506:1-464)
20 30 40 50 60 70
pF1KE1 GARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQSENNEDYEIPPI
::::::::::::::::::::::::::::::
NP_116 MSDGNPELLSTSQTYNGQSENNEDYEIPPI
10 20 30
80 90 100 110 120 130
pF1KE1 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 GQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 GQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 YALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 YALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAA
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE1 YRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 YRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPAS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE1 LARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVL
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE1 PTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 PTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGIS
400 410 420 430 440 450
500
pF1KE1 TCSLLPRDKSLYLT
::::::::::::::
NP_116 TCSLLPRDKSLYLT
460
>>NP_001092268 (OMIM: 611163) TOX high mobility group bo (488 aa)
initn: 1792 init1: 1743 opt: 1812 Z-score: 827.8 bits: 162.7 E(85289): 2.3e-39
Smith-Waterman score: 2976; 94.3% identity (94.3% similar) in 474 aa overlap (33-506:42-488)
10 20 30 40 50 60
pF1KE1 VRLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQSE
::::::::::::::::::::::::::::::
NP_001 AFSRCLGFCGMRLGLLLLARHWCIAGVFPQKFDGDSAYVGMSDGNPELLSTSQTYNGQSE
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE1 NNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSN
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE1 MLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGI
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE1 RSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKD
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE1 PNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAA
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQ---------
260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQ
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------SSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQ
310 320 330 340
370 380 390 400 410 420
pF1KE1 AFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE1 MSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDS
410 420 430 440 450 460
490 500
pF1KE1 SYPSGECGISTCSLLPRDKSLYLT
::::::::::::::::::::::::
NP_001 SYPSGECGISTCSLLPRDKSLYLT
470 480
>>XP_016883598 (OMIM: 611163) PREDICTED: TOX high mobili (305 aa)
initn: 1678 init1: 1678 opt: 1678 Z-score: 771.0 bits: 151.5 E(85289): 3.3e-36
Smith-Waterman score: 1734; 65.7% identity (65.7% similar) in 464 aa overlap (43-506:1-305)
20 30 40 50 60 70
pF1KE1 GARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQSENNEDYEIPPI
::::::::::::::::::::::::::::::
XP_016 MSDGNPELLSTSQTYNGQSENNEDYEIPPI
10 20 30
80 90 100 110 120 130
pF1KE1 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE1 GQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE1 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 YALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAA
:::::::::::::::::::::::::::::::::::::::::
XP_016 YALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQ-------------------
220 230 240 250
320 330 340 350 360 370
pF1KE1 YRASLVSKSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPAS
XP_016 ------------------------------------------------------------
380 390 400 410 420 430
pF1KE1 LARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVL
XP_016 ------------------------------------------------------------
440 450 460 470 480 490
pF1KE1 PTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGIS
::::::::::::::::::::::::::::::::::::::::
XP_016 --------------------DFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGIS
260 270 280 290
500
pF1KE1 TCSLLPRDKSLYLT
::::::::::::::
XP_016 TCSLLPRDKSLYLT
300
>>XP_016869574 (OMIM: 606863) PREDICTED: thymocyte selec (504 aa)
initn: 1033 init1: 629 opt: 907 Z-score: 426.9 bits: 88.5 E(85289): 4.8e-17
Smith-Waterman score: 1281; 45.1% identity (67.0% similar) in 545 aa overlap (1-506:1-504)
10 20 30 40 50
pF1KE1 MDVRLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPEL--LSTSQTYN
::::.:: :: .:.: : :. .: : : : ...:
XP_016 MDVRFYPP-PA---QPAAAP----------------DAPCLGPS---PCLDPYYCNKSYP
10 20 30
60 70 80 90 100 110
pF1KE1 GQSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAI
: : ..::..:::::::.::. ::.::.. :..:::::: .. ::::: . : :::: :
XP_016 GPSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLP-FHPQNMDLPEI
40 50 60 70 80 90
120 130 140 150 160
pF1KE1 MVSNMLAQDSHLLSGQ---LPTI------QEMVHSEVAAY-DSGRPGPLLGRPAMLA-SH
:::::.::. :::.. .: : : : ..::. :.:. . .:.:. ..
XP_016 TVSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQ
100 110 120 130 140 150
170 180 190 200 210 220
pF1KE1 MSALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISG-EKR
.....:::: .:.:. :.. :.:::::::::::::::::..:.:.. ::.: :::
XP_016 LTTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKR
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE1 PSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASM
:..: ::: :.:::::::::::::::::::::::::::::::::::.::::.::::::::
XP_016 PASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASM
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE1 WDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPK
::.:::::::.::.::::::::::: :::::::::::: . ..:..: :: ... :
XP_016 WDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQ--PP-QLINSK
280 290 300 310 320 330
350 360 370 380
pF1KE1 QPMYAMPGLA-SFLTPSDLQAFRSGASP------ASLARTLGSK--SLLP------GLSA
.. :. : : : :. . : .: :: :... : . .: ....
XP_016 PSVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAV
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE1 SPPPPPSFPLSPTLHQQLSLPPHAQGALLSP-----PVSMSPAPQPPVLPTPMALQ--VQ
::::: . .:: :::.:.. : .. .: :.... : . :.. ..:: :
XP_016 SPPPP--LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQ
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE1 LAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDK
..:. . : . :. :. : : .:. ::...: : . . . :::
XP_016 TIINPTSTAAQVVTQAMEYVRSG--CRNPPPQPV---DWNNDY----C---SSGGMQRDK
460 470 480 490
pF1KE1 SLYLT
.::::
XP_016 ALYLT
500
>>NP_055544 (OMIM: 606863) thymocyte selection-associate (526 aa)
initn: 1110 init1: 629 opt: 906 Z-score: 426.2 bits: 88.5 E(85289): 5.3e-17
Smith-Waterman score: 1389; 46.1% identity (69.5% similar) in 544 aa overlap (1-506:1-526)
10 20 30 40 50
pF1KE1 MDVRLYPSAPAVGARPGAEPAGLAH-LDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNG
::::.:: .: : : : . :: :. .::::.. :..:.. . . . .::.: :
NP_055 MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIM
: ..::..:::::::.::. ::.::.. :..:::::: .. ::::: . : :::: :
NP_055 PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLP-FHPQNMDLPEIT
70 80 90 100 110
120 130 140 150 160
pF1KE1 VSNMLAQDSHLLSGQ---LPTI------QEMVHSEVAAY-DSGRPGPLLGRPAMLA-SHM
:::::.::. :::.. .: : : : ..::. :.:. . .:.:. ...
NP_055 VSNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 SALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISG-EKRP
....:::: .:.:. :.. :.:::::::::::::::::..:.:.. ::.: ::::
NP_055 TTINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 SADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMW
..: ::: :.:::::::::::::::::::::::::::::::::::.::::.:::::::::
NP_055 ASDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 DSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQ
:.:::::::.::.::::::::::: :::::::::::: . ..:..: :: ... :
NP_055 DGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQ--PP-QLINSKP
300 310 320 330 340 350
350 360 370 380
pF1KE1 PMYAMPGLA-SFLTPSDLQAFRSGASP------ASLARTLGSK--SLLP------GLSAS
.. :. : : : :. . : .: :: :... : . .: ....:
NP_055 SVFHGPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVS
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE1 PPPPPSFPLSPTLHQQLSLPPHAQGALLSP-----PVSMSPAPQPPVLPTPMALQ--VQL
:::: . .:: :::.:.. : .. .: :.... : . :.. ..:: :
NP_055 PPPP--LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQT
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE1 AMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKS
..:. . : . :. :. : : .:. ::...: : . . . :::.
NP_055 IINPTSTAAQVVTQAMEYVRSG--CRNPPPQPV---DWNNDY----C---SSGGMQRDKA
480 490 500 510 520
pF1KE1 LYLT
::::
NP_055 LYLT
>>XP_011521304 (OMIM: 611416) PREDICTED: TOX high mobili (553 aa)
initn: 817 init1: 738 opt: 829 Z-score: 391.9 bits: 82.2 E(85289): 4.3e-15
Smith-Waterman score: 977; 42.9% identity (66.9% similar) in 441 aa overlap (34-452:7-430)
10 20 30 40 50 60
pF1KE1 RLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTS-QTYNGQSE
: ... :..:...: ....: ::.. :
XP_011 MAQFICFGNNNNYMNMAEANNAFFAASEQTFHTPSL
10 20 30
70 80 90 100 110 120
pF1KE1 NNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNG--LLPAYSYQAMDLPAIMV
..:..:::::::: .:.: . : ...: : .: . : . :..:::.: .
XP_011 GDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITI
40 50 60 70 80 90
130 140 150 160
pF1KE1 S-NMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGP-LLGRP-----------AMLASH
: :.. ::. : :. : : :..:. : : : :. : .: ..
XP_011 SRNLVEQDGVLHSSGLHMDQS--HTQVSQY---RQDPSLIMRSIVHMTDAARSGVMPPAQ
100 110 120 130 140 150
170 180 190 200 210 220
pF1KE1 MSALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRP
.....:::: .:.:. .:. :.:::::.::::::::::: .::... . ::::
XP_011 LTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEKRA
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE1 SADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMW
. : ::: :.:::::::::::::::::::::::::::::::::::.::::.:::::::::
XP_011 APDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE1 DSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQ
:::::::::.::::::::::::::::::::::::::.. ...:... .. .:
XP_011 DSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSV--------QQ
280 290 300 310 320
350 360 370 380 390 400
pF1KE1 PMYAMPGLASFLTPSDL-QAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLH
. . .:.: . : : .::: .: ..: .:. : . : .. : :.
XP_011 TLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSL-PRSIAPKPLTMRLPMNQIVTSVTI-
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE1 QQLSLPPHAQGALLSP--PVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFP
..: . . :.: . .. ::. : :. .. : :. .. . :
XP_011 -AANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQ
390 400 410 420 430
470 480 490 500
pF1KE1 SSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKSLYLT
XP_011 QLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHM
440 450 460 470 480 490
>>NP_001139660 (OMIM: 611416) TOX high mobility group bo (571 aa)
initn: 856 init1: 738 opt: 829 Z-score: 391.7 bits: 82.2 E(85289): 4.4e-15
Smith-Waterman score: 990; 42.9% identity (67.1% similar) in 441 aa overlap (33-452:25-448)
10 20 30 40 50 60
pF1KE1 VRLYPSAPAVGARPGAEPAGLAHLDYYHGGKFDGDSAYVGMSDGNPELLSTSQTYNGQSE
:: ... :..:...: ....:.:.. :
NP_001 MKCQPRSGARRIEERLHYLITTYLKFGNNNNYMNMAEANNAFFAASETFHTPSL
10 20 30 40 50
70 80 90 100 110 120
pF1KE1 NNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNG--LLPAYSYQAMDLPAIMV
..:..:::::::: .:.: . : ...: : .: . : . :..:::.: .
NP_001 GDEEFEIPPITPPPESDPAL-GMPDVLLPFQALSDPLPSQGSEFTPQFPPQSLDLPSITI
60 70 80 90 100 110
130 140 150 160
pF1KE1 S-NMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGP-LLGRP-----------AMLASH
: :.. ::. : :. : : :..:. : : : :. : .: ..
NP_001 SRNLVEQDGVLHSSGLHMDQS--HTQVSQY---RQDPSLIMRSIVHMTDAARSGVMPPAQ
120 130 140 150 160
170 180 190 200 210 220
pF1KE1 MSALSQSQLISQMGIR---SSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRP
.....:::: .:.:. .:. :.:::::.::::::::::: .::... . ::::
NP_001 LTTINQSQLSAQLGLNLGGASMPHTSPSPPASKSATPSPSSSINEEDADEANRAIGEKRA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 SADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMW
. : ::: :.:::::::::::::::::::::::::::::::::::.::::.:::::::::
NP_001 APDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMW
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 DSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSSPDQGETKSTQANPPAKMLPPKQ
:::::::::.::::::::::::::::::::::::::.. ...:... .. .:
NP_001 DSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAESAEAQTIRSV--------QQ
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE1 PMYAMPGLASFLTPSDL-QAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLH
. . .:.: . : : .::: .: ..: .:. : . : .. : :.
NP_001 TLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSL-PRSIAPKPLTMRLPMNQIVTSVTI-
350 360 370 380 390
410 420 430 440 450 460
pF1KE1 QQLSLPPHAQGALLSP--PVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFP
..: . . :.: . .. ::. : :. .. : :. .. . :
NP_001 -AANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQHQMQLQQQQQQQQQQMQQMQQQ
400 410 420 430 440 450
470 480 490 500
pF1KE1 SSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKSLYLT
NP_001 QLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHM
460 470 480 490 500 510
506 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:46:04 2016 done: Sun Nov 6 09:46:06 2016
Total Scan time: 12.970 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]