Result of FASTA (omim) for
pFN21AE1230
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1230, 343 aa
1>>>pF1KE1230 343 - 343 aa - 343 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2740+/-0.000419; mu= 16.1566+/- 0.026
mean_var=59.6592+/-11.983, 0's: 0 Z-trim(111.0): 12 B-trim: 343 in 1/48
Lambda= 0.166049
statistics sampled from 19425 (19435) to 19425 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.228), width: 16
Scan time: 5.250
The best scores are: opt bits E(85289)
NP_000502 (OMIM: 182100,612542) galactoside 2-alph ( 343) 2362 574.4 1.2e-163
NP_001091107 (OMIM: 182100,612542) galactoside 2-a ( 343) 2362 574.4 1.2e-163
NP_000139 (OMIM: 211100,616754) galactoside 2-alph ( 365) 1413 347.1 3.5e-95
NP_001316806 (OMIM: 211100,616754) galactoside 2-a ( 365) 1413 347.1 3.5e-95
XP_016882042 (OMIM: 211100,616754) PREDICTED: gala ( 365) 1413 347.1 3.5e-95
XP_006723190 (OMIM: 211100,616754) PREDICTED: gala ( 488) 1413 347.1 4.6e-95
XP_016882041 (OMIM: 211100,616754) PREDICTED: gala ( 488) 1413 347.1 4.6e-95
>>NP_000502 (OMIM: 182100,612542) galactoside 2-alpha-L- (343 aa)
initn: 2362 init1: 2362 opt: 2362 Z-score: 3058.8 bits: 574.4 E(85289): 1.2e-163
Smith-Waterman score: 2362; 100.0% identity (100.0% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KE1 MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTG
250 260 270 280 290 300
310 320 330 340
pF1KE1 GDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
:::::::::::::::::::::::::::::::::::::::::::
NP_000 GDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
310 320 330 340
>>NP_001091107 (OMIM: 182100,612542) galactoside 2-alpha (343 aa)
initn: 2362 init1: 2362 opt: 2362 Z-score: 3058.8 bits: 574.4 E(85289): 1.2e-163
Smith-Waterman score: 2362; 100.0% identity (100.0% similar) in 343 aa overlap (1-343:1-343)
10 20 30 40 50 60
pF1KE1 MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVVQMPFSFPMAHFILFVFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGMWTINAIGRLGNQMGEYATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPWQNYHLNDWMEEEYRHIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 FLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLRGLQVNGSRPGTFVGVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTSNGMAWCRENIDTSHGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTG
250 260 270 280 290 300
310 320 330 340
pF1KE1 GDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
:::::::::::::::::::::::::::::::::::::::::::
NP_001 GDTIYLANYTLPDSPFLKIFKPEAAFLPEWTGIAADLSPLLKH
310 320 330 340
>>NP_000139 (OMIM: 211100,616754) galactoside 2-alpha-L- (365 aa)
initn: 1436 init1: 866 opt: 1413 Z-score: 1829.7 bits: 347.1 E(85289): 3.5e-95
Smith-Waterman score: 1413; 67.7% identity (85.4% similar) in 294 aa overlap (49-340:66-359)
20 30 40 50 60 70
pF1KE1 VFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGE
::.: :..: : ::. ::.:::::.
NP_000 LGLSILCPDRRLVTPPVAIFCLPGTAMGPNASSSCPQHPASLSGTWTVYPNGRFGNQMGQ
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE1 YATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYR
:::: :::..::: ::: ::..:::.:::::::: . :: ::.. .:.::: :::
NP_000 YATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELQLHDWMSEEYA
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE1 HIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVN--GSRPGTFV
. .....:.::::::.::::..: .:::::::.:::::. : :... :.:: :::
NP_000 DLRDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREEAQSVLGQLRLGRTGDRPRTFV
160 170 180 190 200 210
200 210 220 230 240 250
pF1KE1 GVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTS
:::::::::..:::. :::::.: ::.::.::::::. . .:::::::: ::.::::::
NP_000 GVHVRRGDYLQVMPQRWKGVVGDSAYLRQAMDWFRARHEAPVFVVTSNGMEWCKENIDTS
220 230 240 250 260 270
260 270 280 290 300 310
pF1KE1 HGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPF
.:::.::::: :..: ::::::::::::::::::::.:::::.::::.::::.::::: :
NP_000 QGDVTFAGDGQEATPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEF
280 290 300 310 320 330
320 330 340
pF1KE1 LKIFKPEAAFLPEWTGIAADLSPLLKH
::::::::::::::.:: ::::::
NP_000 LKIFKPEAAFLPEWVGINADLSPLWTLAKP
340 350 360
>>NP_001316806 (OMIM: 211100,616754) galactoside 2-alpha (365 aa)
initn: 1436 init1: 866 opt: 1413 Z-score: 1829.7 bits: 347.1 E(85289): 3.5e-95
Smith-Waterman score: 1413; 67.7% identity (85.4% similar) in 294 aa overlap (49-340:66-359)
20 30 40 50 60 70
pF1KE1 VFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGE
::.: :..: : ::. ::.:::::.
NP_001 LGLSILCPDRRLVTPPVAIFCLPGTAMGPNASSSCPQHPASLSGTWTVYPNGRFGNQMGQ
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE1 YATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYR
:::: :::..::: ::: ::..:::.:::::::: . :: ::.. .:.::: :::
NP_001 YATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELQLHDWMSEEYA
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE1 HIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVN--GSRPGTFV
. .....:.::::::.::::..: .:::::::.:::::. : :... :.:: :::
NP_001 DLRDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREEAQSVLGQLRLGRTGDRPRTFV
160 170 180 190 200 210
200 210 220 230 240 250
pF1KE1 GVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTS
:::::::::..:::. :::::.: ::.::.::::::. . .:::::::: ::.::::::
NP_001 GVHVRRGDYLQVMPQRWKGVVGDSAYLRQAMDWFRARHEAPVFVVTSNGMEWCKENIDTS
220 230 240 250 260 270
260 270 280 290 300 310
pF1KE1 HGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPF
.:::.::::: :..: ::::::::::::::::::::.:::::.::::.::::.::::: :
NP_001 QGDVTFAGDGQEATPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEF
280 290 300 310 320 330
320 330 340
pF1KE1 LKIFKPEAAFLPEWTGIAADLSPLLKH
::::::::::::::.:: ::::::
NP_001 LKIFKPEAAFLPEWVGINADLSPLWTLAKP
340 350 360
>>XP_016882042 (OMIM: 211100,616754) PREDICTED: galactos (365 aa)
initn: 1436 init1: 866 opt: 1413 Z-score: 1829.7 bits: 347.1 E(85289): 3.5e-95
Smith-Waterman score: 1413; 67.7% identity (85.4% similar) in 294 aa overlap (49-340:66-359)
20 30 40 50 60 70
pF1KE1 VFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGE
::.: :..: : ::. ::.:::::.
XP_016 LGLSILCPDRRLVTPPVAIFCLPGTAMGPNASSSCPQHPASLSGTWTVYPNGRFGNQMGQ
40 50 60 70 80 90
80 90 100 110 120 130
pF1KE1 YATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYR
:::: :::..::: ::: ::..:::.:::::::: . :: ::.. .:.::: :::
XP_016 YATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELQLHDWMSEEYA
100 110 120 130 140 150
140 150 160 170 180 190
pF1KE1 HIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVN--GSRPGTFV
. .....:.::::::.::::..: .:::::::.:::::. : :... :.:: :::
XP_016 DLRDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREEAQSVLGQLRLGRTGDRPRTFV
160 170 180 190 200 210
200 210 220 230 240 250
pF1KE1 GVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTS
:::::::::..:::. :::::.: ::.::.::::::. . .:::::::: ::.::::::
XP_016 GVHVRRGDYLQVMPQRWKGVVGDSAYLRQAMDWFRARHEAPVFVVTSNGMEWCKENIDTS
220 230 240 250 260 270
260 270 280 290 300 310
pF1KE1 HGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPF
.:::.::::: :..: ::::::::::::::::::::.:::::.::::.::::.::::: :
XP_016 QGDVTFAGDGQEATPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEF
280 290 300 310 320 330
320 330 340
pF1KE1 LKIFKPEAAFLPEWTGIAADLSPLLKH
::::::::::::::.:: ::::::
XP_016 LKIFKPEAAFLPEWVGINADLSPLWTLAKP
340 350 360
>>XP_006723190 (OMIM: 211100,616754) PREDICTED: galactos (488 aa)
initn: 1436 init1: 866 opt: 1413 Z-score: 1827.7 bits: 347.1 E(85289): 4.6e-95
Smith-Waterman score: 1413; 67.7% identity (85.4% similar) in 294 aa overlap (49-340:189-482)
20 30 40 50 60 70
pF1KE1 VFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGE
::.: :..: : ::. ::.:::::.
XP_006 LGLSILCPDRRLVTPPVAIFCLPGTAMGPNASSSCPQHPASLSGTWTVYPNGRFGNQMGQ
160 170 180 190 200 210
80 90 100 110 120 130
pF1KE1 YATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYR
:::: :::..::: ::: ::..:::.:::::::: . :: ::.. .:.::: :::
XP_006 YATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELQLHDWMSEEYA
220 230 240 250 260 270
140 150 160 170 180 190
pF1KE1 HIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVN--GSRPGTFV
. .....:.::::::.::::..: .:::::::.:::::. : :... :.:: :::
XP_006 DLRDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREEAQSVLGQLRLGRTGDRPRTFV
280 290 300 310 320 330
200 210 220 230 240 250
pF1KE1 GVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTS
:::::::::..:::. :::::.: ::.::.::::::. . .:::::::: ::.::::::
XP_006 GVHVRRGDYLQVMPQRWKGVVGDSAYLRQAMDWFRARHEAPVFVVTSNGMEWCKENIDTS
340 350 360 370 380 390
260 270 280 290 300 310
pF1KE1 HGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPF
.:::.::::: :..: ::::::::::::::::::::.:::::.::::.::::.::::: :
XP_006 QGDVTFAGDGQEATPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEF
400 410 420 430 440 450
320 330 340
pF1KE1 LKIFKPEAAFLPEWTGIAADLSPLLKH
::::::::::::::.:: ::::::
XP_006 LKIFKPEAAFLPEWVGINADLSPLWTLAKP
460 470 480
>>XP_016882041 (OMIM: 211100,616754) PREDICTED: galactos (488 aa)
initn: 1436 init1: 866 opt: 1413 Z-score: 1827.7 bits: 347.1 E(85289): 4.6e-95
Smith-Waterman score: 1413; 67.7% identity (85.4% similar) in 294 aa overlap (49-340:189-482)
20 30 40 50 60 70
pF1KE1 VFTVSTIFHVQQRLAKIQAMWELPVQIPVLASTSKALGPSQLRGMWTINAIGRLGNQMGE
::.: :..: : ::. ::.:::::.
XP_016 LGLSILCPDRRLVTPPVAIFCLPGTAMGPNASSSCPQHPASLSGTWTVYPNGRFGNQMGQ
160 170 180 190 200 210
80 90 100 110 120 130
pF1KE1 YATLYALAKMNGRPAFIPAQMHSTLAPIFRITLPVLHSATASRIPWQNYHLNDWMEEEYR
:::: :::..::: ::: ::..:::.:::::::: . :: ::.. .:.::: :::
XP_016 YATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELQLHDWMSEEYA
220 230 240 250 260 270
140 150 160 170 180 190
pF1KE1 HIPGEYVRFTGYPCSWTFYHHLRQEILQEFTLHDHVREEAQKFLRGLQVN--GSRPGTFV
. .....:.::::::.::::..: .:::::::.:::::. : :... :.:: :::
XP_016 DLRDPFLKLSGFPCSWTFFHHLREQIRREFTLHDHLREEAQSVLGQLRLGRTGDRPRTFV
280 290 300 310 320 330
200 210 220 230 240 250
pF1KE1 GVHVRRGDYVHVMPKVWKGVVADRRYLQQALDWFRARYSSLIFVVTSNGMAWCRENIDTS
:::::::::..:::. :::::.: ::.::.::::::. . .:::::::: ::.::::::
XP_016 GVHVRRGDYLQVMPQRWKGVVGDSAYLRQAMDWFRARHEAPVFVVTSNGMEWCKENIDTS
340 350 360 370 380 390
260 270 280 290 300 310
pF1KE1 HGDVVFAGDGIEGSPAKDFALLTQCNHTIMTIGTFGIWAAYLTGGDTIYLANYTLPDSPF
.:::.::::: :..: ::::::::::::::::::::.:::::.::::.::::.::::: :
XP_016 QGDVTFAGDGQEATPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEF
400 410 420 430 440 450
320 330 340
pF1KE1 LKIFKPEAAFLPEWTGIAADLSPLLKH
::::::::::::::.:: ::::::
XP_016 LKIFKPEAAFLPEWVGINADLSPLWTLAKP
460 470 480
343 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:17:39 2016 done: Tue Nov 8 03:17:40 2016
Total Scan time: 5.250 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]