FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1227, 313 aa
  1>>>pF1KE1227 313 - 313 aa - 313 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0786+/-0.00123; mu= 5.8392+/- 0.072
 mean_var=118.8186+/-25.536, 0's: 0 Z-trim(103.6): 168  B-trim: 40 in 1/48
 Lambda= 0.117661
 statistics sampled from 7282 (7478) to 7282 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.23), width:  16
 Scan time:  2.020

The best scores are:                                      opt bits E(32554)
CCDS2851.2 WDR82 gene_id:80335|Hs108|chr3          ( 313) 2112 370.1 1.2e-102
CCDS6981.1 WDR5 gene_id:11091|Hs108|chr9           ( 334)  401 79.7 3.4e-15
CCDS3012.1 WDR5B gene_id:54554|Hs108|chr3          ( 330)  396 78.9 6.1e-15


>>CCDS2851.2 WDR82 gene_id:80335|Hs108|chr3               (313 aa)
 initn: 2112 init1: 2112 opt: 2112  Z-score: 1956.3  bits: 370.1 E(32554): 1.2e-102
Smith-Waterman score: 2112; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)

               10        20        30        40        50        60
pF1KE1 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 SKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 TFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 KGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 VTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASA
              250       260       270       280       290       300

              310   
pF1KE1 CSNMAFWLPTIDD
       :::::::::::::
CCDS28 CSNMAFWLPTIDD
              310   

>>CCDS6981.1 WDR5 gene_id:11091|Hs108|chr9                (334 aa)
 initn: 380 init1: 149 opt: 401  Z-score: 386.3  bits: 79.7 E(32554): 3.4e-15
Smith-Waterman score: 401; 27.1% identity (60.2% similar) in 284 aa overlap (20-300:44-319)

                          10        20        30        40         
pF1KE1            MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYD
                                     ..  ..   :::::: . ::: :  : .. 
CCDS69 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
            20        30        40        50        60        70   

      50        60        70        80        90       100         
pF1KE1 CQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
         .:: ..:. ..: :.. . ..  .: .: .:.  : :..  .. ..: .. . :::. 
CCDS69 AYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD--DKTLKIWDVSSGKCLKTLKGHSNY
            80        90       100         110       120       130 

     110       120       130       140       150         160       
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCS--FDPEGLIFAAGVN
       :   ...: .. ..:::.:...:.::... .:   .  .. :: .  :. .: .....  
CCDS69 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY
             140       150       160       170       180       190 

       170       180       190       200       210       220       
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGV
       . . ...:  :   :      .. :     . .::: .:: :: .:  . ..: :  :: 
CCDS69 DGLCRIWDTAS---GQCLKTLIDDDNP-PVSFVKFSPNGKYILAATLDNTLKLWDYSKGK
             200          210        220       230       240       

       230       240        250       260       270       280      
pF1KE1 VMHTFGGYANSKAVTLEASFT-PDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
        ..:. :. : :   . :.:.   ...:. ::::. ...:: ..   :  :.: ::  . 
CCDS69 CLKTYTGHKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVI
       250        260       270       280       290        300     

        290       300       310     
pF1KE1 CLQFNPKFMTFASACSNMAFWLPTIDD  
           .:    .:::               
CCDS69 STACHPTENIIASAALENDKTIKLWKSDC
         310       320       330    

>>CCDS3012.1 WDR5B gene_id:54554|Hs108|chr3               (330 aa)
 initn: 370 init1: 145 opt: 396  Z-score: 381.7  bits: 78.9 E(32554): 6.1e-15
Smith-Waterman score: 396; 26.0% identity (60.5% similar) in 296 aa overlap (20-308:40-327)

                          10        20        30        40         
pF1KE1            MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYD
                                     ... ..   :::::: . ::: :  :... 
CCDS30 KAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWG
      10        20        30        40        50        60         

      50        60        70        80        90       100         
pF1KE1 CQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKR
         .:: ..:::...  .. . ..  .. .: .:.  : :..  .....: .. . :::. 
CCDS30 AYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD--DKTLKLWDVRSGKCLKTLKGHSNY
      70        80        90       100         110       120       

     110       120       130       140       150         160       
pF1KE1 VVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCS--FDPEGLIFAAGVN
       :   ...: .. .::::.:.:...:.... .:   .  .. :: .  :.  : ....:  
CCDS30 VFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSY
       130       140       150       160       170       180       

       170       180       190       200       210       220       
pF1KE1 SEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGV
       . . ...:  :   :      .. :     . .::: .:: :: .:  . ..: :  .: 
CCDS30 DGLCRIWDAAS---GQCLKTLVDDDNP-PVSFVKFSPNGKYILTATLDNTLKLWDYSRGR
       190          200       210        220       230       240   

       230       240        250       260       270       280      
pF1KE1 VMHTFGGYANSKAVTLEASFT-PDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPIT
        ..:. :. : :   . :.:.   ...:. ::::. ...:: ..   :  :.: ::  . 
CCDS30 CLKTYTGHKNEK-YCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG-HTDVVI
           250        260       270       280       290        300 

        290       300           310   
pF1KE1 CLQFNPKFMTFASAC----SNMAFWLPTIDD
           .:    .:::     ... .:.     
CCDS30 SAACHPTENLIASAALENDKTIKLWMSNH  
             310       320       330  




313 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 17:45:48 2016 done: Sun Nov  6 17:45:49 2016
 Total Scan time:  2.020 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]