Result of FASTA (omim) for
pFN21AE1164
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1164, 593 aa
1>>>pF1KE1164 593 - 593 aa - 593 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0861+/-0.000429; mu= 11.3490+/- 0.027
mean_var=156.6941+/-31.629, 0's: 0 Z-trim(116.7): 98 B-trim: 234 in 2/51
Lambda= 0.102458
statistics sampled from 27921 (28036) to 27921 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.329), width: 16
Scan time: 10.750
The best scores are: opt bits E(85289)
NP_031384 (OMIM: 609882) metal-response element-bi ( 593) 4077 615.1 2e-175
XP_011539318 (OMIM: 609882) PREDICTED: metal-respo ( 491) 3392 513.8 5.3e-145
NP_001157863 (OMIM: 609882) metal-response element ( 491) 3392 513.8 5.3e-145
NP_001157865 (OMIM: 609882) metal-response element ( 491) 3392 513.8 5.3e-145
XP_016856165 (OMIM: 609882) PREDICTED: metal-respo ( 491) 3392 513.8 5.3e-145
NP_001157864 (OMIM: 609882) metal-response element ( 536) 2379 364.1 6.7e-100
XP_011539319 (OMIM: 609882) PREDICTED: metal-respo ( 331) 2208 338.6 1.9e-92
XP_011539321 (OMIM: 609882) PREDICTED: metal-respo ( 320) 1870 288.7 2e-77
XP_016856168 (OMIM: 609882) PREDICTED: metal-respo ( 320) 1870 288.7 2e-77
XP_016856166 (OMIM: 609882) PREDICTED: metal-respo ( 434) 1694 262.8 1.7e-69
XP_016856167 (OMIM: 609882) PREDICTED: metal-respo ( 434) 1694 262.8 1.7e-69
XP_011516811 (OMIM: 609740) PREDICTED: PHD finger ( 580) 1673 259.8 1.8e-68
XP_016870101 (OMIM: 609740) PREDICTED: PHD finger ( 580) 1673 259.8 1.8e-68
NP_056466 (OMIM: 609740) PHD finger protein 19 iso ( 580) 1673 259.8 1.8e-68
XP_005251963 (OMIM: 609740) PREDICTED: PHD finger ( 580) 1673 259.8 1.8e-68
NP_001273769 (OMIM: 609740) PHD finger protein 19 ( 599) 1673 259.8 1.9e-68
XP_011516817 (OMIM: 609740) PREDICTED: PHD finger ( 422) 1390 217.8 5.7e-56
XP_011516813 (OMIM: 609740) PREDICTED: PHD finger ( 473) 1390 217.9 6.2e-56
XP_011516818 (OMIM: 609740) PREDICTED: PHD finger ( 388) 1378 216.0 1.8e-55
XP_016870102 (OMIM: 609740) PREDICTED: PHD finger ( 443) 1378 216.1 2e-55
XP_011512968 (OMIM: 602881) PREDICTED: PHD finger ( 498) 1359 213.3 1.5e-54
XP_011512967 (OMIM: 602881) PREDICTED: PHD finger ( 499) 1359 213.3 1.5e-54
XP_011512965 (OMIM: 602881) PREDICTED: PHD finger ( 566) 1355 212.8 2.6e-54
XP_011512964 (OMIM: 602881) PREDICTED: PHD finger ( 567) 1355 212.8 2.6e-54
NP_077084 (OMIM: 602881) PHD finger protein 1 isof ( 567) 1355 212.8 2.6e-54
XP_011512971 (OMIM: 602881) PREDICTED: PHD finger ( 429) 1337 210.0 1.3e-53
NP_002627 (OMIM: 602881) PHD finger protein 1 isof ( 457) 1336 209.9 1.5e-53
XP_011512972 (OMIM: 602881) PREDICTED: PHD finger ( 415) 1332 209.2 2.2e-53
NP_001273771 (OMIM: 609740) PHD finger protein 19 ( 371) 964 154.8 4.7e-37
XP_011512966 (OMIM: 602881) PREDICTED: PHD finger ( 535) 719 118.7 4.9e-26
NP_001009936 (OMIM: 609740) PHD finger protein 19 ( 207) 436 76.5 9.6e-14
NP_001273772 (OMIM: 609740) PHD finger protein 19 ( 130) 324 59.8 6.6e-09
XP_006718902 (OMIM: 159555,605130) PREDICTED: hist (3133) 208 43.9 0.0097
XP_011541135 (OMIM: 159555,605130) PREDICTED: hist (3166) 208 43.9 0.0097
>>NP_031384 (OMIM: 609882) metal-response element-bindin (593 aa)
initn: 4077 init1: 4077 opt: 4077 Z-score: 3270.4 bits: 615.1 E(85289): 2e-175
Smith-Waterman score: 4077; 100.0% identity (100.0% similar) in 593 aa overlap (1-593:1-593)
10 20 30 40 50 60
pF1KE1 MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 FYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 ICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 TLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 GDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 DRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 AEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 AEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 KRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 KRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLAD
490 500 510 520 530 540
550 560 570 580 590
pF1KE1 QELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 QELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
550 560 570 580 590
>>XP_011539318 (OMIM: 609882) PREDICTED: metal-response (491 aa)
initn: 3392 init1: 3392 opt: 3392 Z-score: 2724.3 bits: 513.8 E(85289): 5.3e-145
Smith-Waterman score: 3392; 100.0% identity (100.0% similar) in 491 aa overlap (103-593:1-491)
80 90 100 110 120 130
pF1KE1 KQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQL
::::::::::::::::::::::::::::::
XP_011 MVCTICQEEYSEAPNEMVICDKCGQGYHQL
10 20 30
140 150 160 170 180 190
pF1KE1 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
400 410 420 430 440 450
560 570 580 590
pF1KE1 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::
XP_011 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
460 470 480 490
>>NP_001157863 (OMIM: 609882) metal-response element-bin (491 aa)
initn: 3392 init1: 3392 opt: 3392 Z-score: 2724.3 bits: 513.8 E(85289): 5.3e-145
Smith-Waterman score: 3392; 100.0% identity (100.0% similar) in 491 aa overlap (103-593:1-491)
80 90 100 110 120 130
pF1KE1 KQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQL
::::::::::::::::::::::::::::::
NP_001 MVCTICQEEYSEAPNEMVICDKCGQGYHQL
10 20 30
140 150 160 170 180 190
pF1KE1 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
400 410 420 430 440 450
560 570 580 590
pF1KE1 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::
NP_001 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
460 470 480 490
>>NP_001157865 (OMIM: 609882) metal-response element-bin (491 aa)
initn: 3392 init1: 3392 opt: 3392 Z-score: 2724.3 bits: 513.8 E(85289): 5.3e-145
Smith-Waterman score: 3392; 100.0% identity (100.0% similar) in 491 aa overlap (103-593:1-491)
80 90 100 110 120 130
pF1KE1 KQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQL
::::::::::::::::::::::::::::::
NP_001 MVCTICQEEYSEAPNEMVICDKCGQGYHQL
10 20 30
140 150 160 170 180 190
pF1KE1 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
400 410 420 430 440 450
560 570 580 590
pF1KE1 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::
NP_001 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
460 470 480 490
>>XP_016856165 (OMIM: 609882) PREDICTED: metal-response (491 aa)
initn: 3392 init1: 3392 opt: 3392 Z-score: 2724.3 bits: 513.8 E(85289): 5.3e-145
Smith-Waterman score: 3392; 100.0% identity (100.0% similar) in 491 aa overlap (103-593:1-491)
80 90 100 110 120 130
pF1KE1 KQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQL
::::::::::::::::::::::::::::::
XP_016 MVCTICQEEYSEAPNEMVICDKCGQGYHQL
10 20 30
140 150 160 170 180 190
pF1KE1 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE1 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE1 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE1 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
400 410 420 430 440 450
560 570 580 590
pF1KE1 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::
XP_016 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
460 470 480 490
>>NP_001157864 (OMIM: 609882) metal-response element-bin (536 aa)
initn: 2364 init1: 2364 opt: 2379 Z-score: 1914.5 bits: 364.1 E(85289): 6.7e-100
Smith-Waterman score: 3573; 90.4% identity (90.4% similar) in 593 aa overlap (1-593:1-536)
10 20 30 40 50 60
pF1KE1 MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFK
::::::::::::::::::::::::::::::
NP_001 DRLHPGELADTPKSERYEHVLEALNDYKTM------------------------------
310 320 330
370 380 390 400 410 420
pF1KE1 AEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEP
:::::::::::::::::::::::::::::::::
NP_001 ---------------------------EVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEP
340 350 360
430 440 450 460 470 480
pF1KE1 LLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSR
370 380 390 400 410 420
490 500 510 520 530 540
pF1KE1 KRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLAD
430 440 450 460 470 480
550 560 570 580 590
pF1KE1 QELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
490 500 510 520 530
>>XP_011539319 (OMIM: 609882) PREDICTED: metal-response (331 aa)
initn: 2208 init1: 2208 opt: 2208 Z-score: 1780.7 bits: 338.6 E(85289): 1.9e-92
Smith-Waterman score: 2208; 99.7% identity (100.0% similar) in 308 aa overlap (1-308:1-308)
10 20 30 40 50 60
pF1KE1 MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRDSTGAGNSLVHKRSPLRRNQKTPTSLTKLSLQDGHKAKKPACKFEEGQDVLARWSDGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 GDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 DRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFK
:::::::.
XP_011 DRLHPGEFWGQISLVWISGPAFSSSCVFVAC
310 320 330
>>XP_011539321 (OMIM: 609882) PREDICTED: metal-response (320 aa)
initn: 1870 init1: 1870 opt: 1870 Z-score: 1510.8 bits: 288.7 E(85289): 2e-77
Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 286 aa overlap (308-593:35-320)
280 290 300 310 320 330
pF1KE1 SVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEI
::::::::::::::::::::::::::::::
XP_011 ANAIWRQILYVYMLCLQFWTRIPQTSTITVLADTPKSERYEHVLEALNDYKTMFMSGKEI
10 20 30 40 50 60
340 350 360 370 380 390
pF1KE1 KKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKG
70 80 90 100 110 120
400 410 420 430 440 450
pF1KE1 KKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFT
130 140 150 160 170 180
460 470 480 490 500 510
pF1KE1 GASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVK
190 200 210 220 230 240
520 530 540 550 560 570
pF1KE1 DDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTL
250 260 270 280 290 300
580 590
pF1KE1 DGKVQYLVEWEGATAS
::::::::::::::::
XP_011 DGKVQYLVEWEGATAS
310 320
>>XP_016856168 (OMIM: 609882) PREDICTED: metal-response (320 aa)
initn: 1870 init1: 1870 opt: 1870 Z-score: 1510.8 bits: 288.7 E(85289): 2e-77
Smith-Waterman score: 1870; 100.0% identity (100.0% similar) in 286 aa overlap (308-593:35-320)
280 290 300 310 320 330
pF1KE1 SVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEI
::::::::::::::::::::::::::::::
XP_016 ANAIWRQILYVYMLCLQFWTRIPQTSTITVLADTPKSERYEHVLEALNDYKTMFMSGKEI
10 20 30 40 50 60
340 350 360 370 380 390
pF1KE1 KKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPISDSREVSNGIEKKG
70 80 90 100 110 120
400 410 420 430 440 450
pF1KE1 KKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPTLDLPCSIGRTEGTAHSSNTSDVDFT
130 140 150 160 170 180
460 470 480 490 500 510
pF1KE1 GASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEIVK
190 200 210 220 230 240
520 530 540 550 560 570
pF1KE1 DDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDEGKEDYQFDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTL
250 260 270 280 290 300
580 590
pF1KE1 DGKVQYLVEWEGATAS
::::::::::::::::
XP_016 DGKVQYLVEWEGATAS
310 320
>>XP_016856166 (OMIM: 609882) PREDICTED: metal-response (434 aa)
initn: 1679 init1: 1679 opt: 1694 Z-score: 1368.5 bits: 262.8 E(85289): 1.7e-69
Smith-Waterman score: 2888; 88.4% identity (88.4% similar) in 491 aa overlap (103-593:1-434)
80 90 100 110 120 130
pF1KE1 KQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQL
::::::::::::::::::::::::::::::
XP_016 MVCTICQEEYSEAPNEMVICDKCGQGYHQL
10 20 30
140 150 160 170 180 190
pF1KE1 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE1 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE1 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE1 KSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEF
::::::::::::::::::
XP_016 KSERYEHVLEALNDYKTM------------------------------------------
220
380 390 400 410 420 430
pF1KE1 KIKGRKASKPISDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------EVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPLLDKESISENPT
230 240 250 260 270
440 450 460 470 480 490
pF1KE1 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLPCSIGRTEGTAHSSNTSDVDFTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAA
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE1 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPHLRRRRGRLPRRALQTQNSEIVKDDEGKEDYQFDELNTEILNNLADQELQLNHLKNSI
340 350 360 370 380 390
560 570 580 590
pF1KE1 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
:::::::::::::::::::::::::::::::::::::::::
XP_016 TSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS
400 410 420 430
593 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:12:57 2016 done: Sun Nov 6 19:12:58 2016
Total Scan time: 10.750 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]