Result of FASTA (omim) for
pFN21AE1153
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1153, 500 aa
1>>>pF1KE1153 500 - 500 aa - 500 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5532+/-0.000329; mu= 4.0129+/- 0.021
mean_var=167.1089+/-33.439, 0's: 0 Z-trim(120.7): 17 B-trim: 263 in 1/57
Lambda= 0.099214
statistics sampled from 36308 (36325) to 36308 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.426), width: 16
Scan time: 7.230
The best scores are: opt bits E(85289)
NP_005643 (OMIM: 602027) telomeric repeat-binding ( 542) 3273 480.3 6e-135
XP_005256178 (OMIM: 602027) PREDICTED: telomeric r ( 545) 3257 478.0 2.9e-134
XP_005256180 (OMIM: 602027) PREDICTED: telomeric r ( 541) 3256 477.9 3.2e-134
XP_005256179 (OMIM: 602027) PREDICTED: telomeric r ( 544) 3240 475.6 1.6e-133
XP_005256181 (OMIM: 602027) PREDICTED: telomeric r ( 464) 1730 259.4 1.6e-68
XP_011515884 (OMIM: 600951) PREDICTED: telomeric r ( 365) 240 46.1 0.00021
XP_005251348 (OMIM: 600951) PREDICTED: telomeric r ( 469) 240 46.2 0.00026
XP_005251349 (OMIM: 600951) PREDICTED: telomeric r ( 449) 235 45.4 0.0004
NP_059523 (OMIM: 600951) telomeric repeat-binding ( 439) 234 45.3 0.00044
XP_016869281 (OMIM: 600951) PREDICTED: telomeric r ( 315) 228 44.3 0.0006
NP_003209 (OMIM: 600951) telomeric repeat-binding ( 419) 228 44.4 0.00076
>>NP_005643 (OMIM: 602027) telomeric repeat-binding fact (542 aa)
initn: 3273 init1: 3273 opt: 3273 Z-score: 2543.8 bits: 480.3 E(85289): 6e-135
Smith-Waterman score: 3273; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:43-542)
10 20 30
pF1KE1 MAGGGGSSDGSGRAAGRRASRSSGRARRGR
::::::::::::::::::::::::::::::
NP_005 GPGVVRDPAASQPRKRPGREGGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE1 NFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPR
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE1 EPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKR
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE1 PRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSK
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE1 PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKW
440 450 460 470 480 490
460 470 480 490 500
pF1KE1 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
500 510 520 530 540
>>XP_005256178 (OMIM: 602027) PREDICTED: telomeric repea (545 aa)
initn: 1809 init1: 1730 opt: 3257 Z-score: 2531.4 bits: 478.0 E(85289): 2.9e-134
Smith-Waterman score: 3257; 99.4% identity (99.4% similar) in 503 aa overlap (1-500:43-545)
10 20 30
pF1KE1 MAGGGGSSDGSGRAAGRRASRSSGRARRGR
::::::::::::::::::::::::::::::
XP_005 GPGVVRDPAASQPRKRPGREGGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
200 210 220 230 240 250
220 230 240 250 260
pF1KE1 NFSYETFQQKMLRFLESHLDDAEPYLLT---MAKKALKSESAASSTGKEDKQPAPGPVEK
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_005 NFSYETFQQKMLRFLESHLDDAEPYLLTIGFMAKKALKSESAASSTGKEDKQPAPGPVEK
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALK
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 NKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAP
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE1 PSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK
440 450 460 470 480 490
450 460 470 480 490 500
pF1KE1 QKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
500 510 520 530 540
>>XP_005256180 (OMIM: 602027) PREDICTED: telomeric repea (541 aa)
initn: 2910 init1: 2831 opt: 3256 Z-score: 2530.7 bits: 477.9 E(85289): 3.2e-134
Smith-Waterman score: 3256; 99.8% identity (99.8% similar) in 500 aa overlap (1-500:43-541)
10 20 30
pF1KE1 MAGGGGSSDGSGRAAGRRASRSSGRARRGR
::::::::::::::::::::::::::::::
XP_005 GPGVVRDPAASQPRKRPGREGGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE1 NFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPR
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE1 EPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKR
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE1 PRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSK
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE1 PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKW
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_005 PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQA-PDEDSTTNITKKQKW
440 450 460 470 480 490
460 470 480 490 500
pF1KE1 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
500 510 520 530 540
>>XP_005256179 (OMIM: 602027) PREDICTED: telomeric repea (544 aa)
initn: 2831 init1: 1557 opt: 3240 Z-score: 2518.2 bits: 475.6 E(85289): 1.6e-133
Smith-Waterman score: 3240; 99.2% identity (99.2% similar) in 503 aa overlap (1-500:43-544)
10 20 30
pF1KE1 MAGGGGSSDGSGRAAGRRASRSSGRARRGR
::::::::::::::::::::::::::::::
XP_005 GPGVVRDPAASQPRKRPGREGGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
200 210 220 230 240 250
220 230 240 250 260
pF1KE1 NFSYETFQQKMLRFLESHLDDAEPYLLT---MAKKALKSESAASSTGKEDKQPAPGPVEK
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_005 NFSYETFQQKMLRFLESHLDDAEPYLLTIGFMAKKALKSESAASSTGKEDKQPAPGPVEK
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALK
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 NKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAP
380 390 400 410 420 430
390 400 410 420 430 440
pF1KE1 PSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKK
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_005 PSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQA-PDEDSTTNITKK
440 450 460 470 480 490
450 460 470 480 490 500
pF1KE1 QKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
500 510 520 530 540
>>XP_005256181 (OMIM: 602027) PREDICTED: telomeric repea (464 aa)
initn: 1809 init1: 1730 opt: 1730 Z-score: 1351.2 bits: 259.4 E(85289): 1.6e-68
Smith-Waterman score: 2605; 84.4% identity (84.4% similar) in 500 aa overlap (1-500:43-464)
10 20 30
pF1KE1 MAGGGGSSDGSGRAAGRRASRSSGRARRGR
::::::::::::::::::::::::::::::
XP_005 GPGVVRDPAASQPRKRPGREGGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGR
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 ESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQ
::::::::::
XP_005 ESSRKLVKEA--------------------------------------------------
200
220 230 240 250 260 270
pF1KE1 NFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPR
::::::::::::::::::::::::::::::::
XP_005 ----------------------------MAKKALKSESAASSTGKEDKQPAPGPVEKPPR
210 220 230
280 290 300 310 320 330
pF1KE1 EPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKR
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE1 PRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSK
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE1 PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKW
360 370 380 390 400 410
460 470 480 490 500
pF1KE1 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN
420 430 440 450 460
>>XP_011515884 (OMIM: 600951) PREDICTED: telomeric repea (365 aa)
initn: 363 init1: 202 opt: 240 Z-score: 200.2 bits: 46.1 E(85289): 0.00021
Smith-Waterman score: 386; 26.4% identity (55.3% similar) in 409 aa overlap (99-499:17-358)
70 80 90 100 110 120
pF1KE1 RGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTP
: . . : :.:: :..:: .:. . ..::
XP_011 MFTIIHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITP
10 20 30 40
130 140 150 160 170 180
pF1KE1 LESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTT
::::. . :. : . . : ..:.: :. .:..: .:..: ..... . ::..
XP_011 LESALMIWGSIEKEH---DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPNS
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE1 Q-KLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALKS
. ... :: :: .:. : .:.:::. ...:. ... :.. . .:. : :...:
XP_011 HMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVES
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE1 ESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFA
. . . :.. :: :. . :: : .: . : ....:...: .
XP_011 KRTRTITSQ-DK-PSGNDVE-------------------METEANLDTRKSVSDKQSAVT
170 180 190 200
310 320 330 340 350 360
pF1KE1 KLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEE
::: :: : ..: . .:. :..
XP_011 ------------------------------ESS-----EGTVSLLRSHKNLFLSK--LQH
210 220
370 380 390 400 410 420
pF1KE1 DSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGK-----WNSSNGVEEKE
.:. . ::.... ...: :.. : .:. : :: . ..::
XP_011 GTQQQD----LNKKERRVGTPQITYICLTK-LTMNKKEGVRKGLCFLVLLKHYRTKKKKE
230 240 250 260 270
430 440 450 460 470 480
pF1KE1 TW-VEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFV
. . :... .. : :.: : ::.. ...::.:::::::. : .: :
XP_011 SRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFN
280 290 300 310 320 330
490 500
pF1KE1 NRTAVMIKDRWRTMKRLGMN
:::.::.::::::::.: .
XP_011 NRTSVMLKDRWRTMKKLKLISSDSED
340 350 360
>>XP_005251348 (OMIM: 600951) PREDICTED: telomeric repea (469 aa)
initn: 403 init1: 202 opt: 240 Z-score: 198.5 bits: 46.2 E(85289): 0.00026
Smith-Waterman score: 455; 26.8% identity (55.3% similar) in 470 aa overlap (40-499:61-462)
10 20 30 40 50 60
pF1KE1 GSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNR-WVLKFYFHEALRAF
:. :: . ::: :.: : :::
XP_005 TERNDEEQFECQELLECQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAF
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 RGSRYGDFRQIRDIMQALLVRPLGKEHTVS-RLLRVMQCLSRIEEGENLDCSFDMEAELT
: .: :::. :. .:. .. :.. . . : . . : :.:: :..:: .:. . ..:
XP_005 RDGRSEDFRRTRNSAEAI-IHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERIT
100 110 120 130 140
130 140 150 160 170 180
pF1KE1 PLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPT
:::::. . :. : . . : ..:.: :. .:..: .:..: ..... . ::.
XP_005 PLESALMIWGSIEKEH---DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPN
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 TQ-KLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALK
.. ... :: :: .:. : .:.:::. ...:. ... :.. . .:. : :...
XP_005 SHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVE
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE1 SESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAF
:. . . :... .:. . :: : .: . : ....:...:
XP_005 SKRTRTITSQD--KPSGNDVE-------------------METEANLDTRKSVSDKQSAV
270 280 290 300
310 320 330 340 350 360
pF1KE1 AKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLE
. ::: :: : ..: . .:. :.
XP_005 T------------------------------ESS-----EGTVSLLRSHKNLFLSK--LQ
310 320
370 380 390 400 410 420
pF1KE1 EDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGK-----WNSSNGVEEK
. .:. . ::.... ...: :.. : .:. : :: . ..:
XP_005 HGTQQQD----LNKKERRVGTPQITYICLTK-LTMNKKEGVRKGLCFLVLLKHYRTKKKK
330 340 350 360 370 380
430 440 450 460 470
pF1KE1 ETW-VEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPF
:. . :... .. : :.: : ::.. ...::.:::::::. : .: :
XP_005 ESRRATESRIPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKF
390 400 410 420 430 440
480 490 500
pF1KE1 VNRTAVMIKDRWRTMKRLGMN
:::.::.::::::::.: .
XP_005 NNRTSVMLKDRWRTMKKLKLISSDSED
450 460
>>XP_005251349 (OMIM: 600951) PREDICTED: telomeric repea (449 aa)
initn: 403 init1: 202 opt: 235 Z-score: 194.9 bits: 45.4 E(85289): 0.0004
Smith-Waterman score: 417; 26.0% identity (53.3% similar) in 465 aa overlap (40-499:61-442)
10 20 30 40 50 60
pF1KE1 GSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNR-WVLKFYFHEALRAF
:. :: . ::: :.: : :::
XP_005 TERNDEEQFECQELLECQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAF
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 RGSRYGDFRQIRDIMQALLVRPLGKEHTVS-RLLRVMQCLSRIEEGENLDCSFDMEAELT
: .: :::. :. .:. .. :.. . . : . . : :.:: :..:: .:. . ..:
XP_005 RDGRSEDFRRTRNSAEAI-IHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERIT
100 110 120 130 140
130 140 150 160 170 180
pF1KE1 PLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPT
:::::. . :. : . . : ..:.: :. .:..: .:..: ..... . ::.
XP_005 PLESALMIWGSIEKEH---DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPN
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 TQ-KLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALK
.. ... :: :: .:. : .:.:::. ...:. ... :.. . .:. : :...
XP_005 SHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVE
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE1 SESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAF
:. . . :... .:. . :: : .. : : . :.: .. ....
XP_005 SKRTRTITSQD--KPSGNDVEME------------TEANLDTRKRSHKNLFLSKLQHGT-
270 280 290 300 310
310 320 330 340 350 360
pF1KE1 AKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLE
.:.:: ::. :. . . . . . .. : . :::
XP_005 ---QQQDL--------------NKKERRVGTPQITYICLTKLTMNKKEGVRKGLCFLVLL
320 330 340 350
370 380 390 400 410 420
pF1KE1 EDSQSTEPSAGLNSSQEAASAPPSK-PTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWV
. .. . ..:. : :. :. .::. ::.
XP_005 KHYRTKK-------KKESRRATESRIPVSKSQPVTPEKH---------------------
360 370 380
430 440 450 460 470 480
pF1KE1 EEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTA
:.: : ::.. ...::.:::::::. : .: : :::.
XP_005 ------------------RARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTS
390 400 410 420
490 500
pF1KE1 VMIKDRWRTMKRLGMN
::.::::::::.: .
XP_005 VMLKDRWRTMKKLKLISSDSED
430 440
>>NP_059523 (OMIM: 600951) telomeric repeat-binding fact (439 aa)
initn: 403 init1: 202 opt: 234 Z-score: 194.3 bits: 45.3 E(85289): 0.00044
Smith-Waterman score: 429; 26.3% identity (53.7% similar) in 464 aa overlap (40-499:61-432)
10 20 30 40 50 60
pF1KE1 GSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNR-WVLKFYFHEALRAF
:. :: . ::: :.: : :::
NP_059 TERNDEEQFECQELLECQVQVGAPEEEEEEEEDAGLVAEAEAVAAGWMLDFLCLSLCRAF
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE1 RGSRYGDFRQIRDIMQALLVRPLGKEHTVS-RLLRVMQCLSRIEEGENLDCSFDMEAELT
: .: :::. :. .:. .. :.. . . : . . : :.:: :..:: .:. . ..:
NP_059 RDGRSEDFRRTRNSAEAI-IHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERIT
100 110 120 130 140
130 140 150 160 170 180
pF1KE1 PLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPT
:::::. . :. : . . : ..:.: :. .:..: .:..: ..... . ::.
NP_059 PLESALMIWGSIEKEH---DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPN
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 TQ-KLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALK
.. ... :: :: .:. : .:.:::. ...:. ... :.. . .:. : :...
NP_059 SHMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVE
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE1 SESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAF
:. . . :... .:. . :: : .: . : ....:...:
NP_059 SKRTRTITSQD--KPSGNDVE-------------------METEANLDTRKSVSDKQSAV
270 280 290 300
310 320 330 340 350 360
pF1KE1 AKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLE
. ::: :: : ..: . .:. :.
NP_059 T------------------------------ESS-----EGTVSLLRSHKNLFLSK--LQ
310 320
370 380 390 400 410 420
pF1KE1 EDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVE
. .:. . ::.... ...: : : : .: ..: .
NP_059 HGTQQQD----LNKKERRVGTPQST-----------------KKKKESRRATESR-----
330 340 350 360
430 440 450 460 470 480
pF1KE1 EDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAV
. .. : :.: : ::.. ...::.:::::::. : .: : :::.:
NP_059 ---IPVSKSQPVTPEKHRARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSV
370 380 390 400 410
490 500
pF1KE1 MIKDRWRTMKRLGMN
:.::::::::.: .
NP_059 MLKDRWRTMKKLKLISSDSED
420 430
>>XP_016869281 (OMIM: 600951) PREDICTED: telomeric repea (315 aa)
initn: 363 init1: 202 opt: 228 Z-score: 191.9 bits: 44.3 E(85289): 0.0006
Smith-Waterman score: 323; 25.8% identity (51.1% similar) in 403 aa overlap (99-499:17-308)
70 80 90 100 110 120
pF1KE1 RGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTP
: . . : :.:: :..:: .:. . ..::
XP_016 MFTIIHGLSSLTACQLRTIYICQFLTRIAAGKTLDAQFENDERITP
10 20 30 40
130 140 150 160 170 180
pF1KE1 LESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTT
::::. . :. : . . : ..:.: :. .:..: .:..: ..... . ::..
XP_016 LESALMIWGSIEKEH---DKLHEEIQNLIKIQAIAVCMENGNFKEAEEVFER-IFGDPNS
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE1 Q-KLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDD-AEPYLLTMAKKALKS
. ... :: :: .:. : .:.:::. ...:. ... :.. . .:. : :...:
XP_016 HMPFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSSTFLMKAAAKVVES
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE1 ESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFA
. . . :.. :: :. . :: : .. : : . :.: .. ....
XP_016 KRTRTITSQ-DK-PSGNDVEME------------TEANLDTRKRSHKNLFLSKLQHGT--
170 180 190 200
310 320 330 340 350 360
pF1KE1 KLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEE
.:.:: ::. :. :. . :.:. :
XP_016 --QQQDL--------------NKKERRV------------GTPQSTKKKK---------E
210 220
370 380 390 400 410 420
pF1KE1 DSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEE
. ..:: . : :: .::. ::.
XP_016 SRRATE-----------SRIPVSK----SQPVTPEKH-----------------------
230 240 250
430 440 450 460 470 480
pF1KE1 DELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVM
:.: : ::.. ...::.:::::::. : .: : :::.::
XP_016 ----------------RARKRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVM
260 270 280 290
490 500
pF1KE1 IKDRWRTMKRLGMN
.::::::::.: .
XP_016 LKDRWRTMKKLKLISSDSED
300 310
500 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:44:48 2016 done: Mon Nov 7 19:44:49 2016
Total Scan time: 7.230 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]