Result of FASTA (omim) for
pFN21AE1152
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1152, 488 aa
1>>>pF1KE1152 488 - 488 aa - 488 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7080+/-0.000364; mu= 16.1818+/- 0.023
mean_var=72.7099+/-14.607, 0's: 0 Z-trim(113.7): 25 B-trim: 0 in 0/52
Lambda= 0.150410
statistics sampled from 23213 (23234) to 23213 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.272), width: 16
Scan time: 9.090
The best scores are: opt bits E(85289)
NP_078886 (OMIM: 608263) HSPB1-associated protein ( 488) 3364 739.4 5.4e-213
XP_011511432 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 451) 3129 688.4 1.1e-197
XP_011511434 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 449) 2806 618.3 1.4e-176
XP_016862668 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 426) 2799 616.7 3.9e-176
XP_005247819 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 280) 1761 391.4 1.7e-108
NP_001307657 (OMIM: 608263) HSPB1-associated prote ( 460) 1744 387.8 3.4e-107
XP_016862669 (OMIM: 608263) PREDICTED: HSPB1-assoc ( 253) 1622 361.2 1.9e-99
NP_060372 (OMIM: 606615) hypoxia-inducible factor ( 349) 325 79.8 1.3e-14
XP_016879169 (OMIM: 611917) PREDICTED: lysine-spec ( 164) 317 78.0 2.3e-14
XP_016879166 (OMIM: 611917) PREDICTED: lysine-spec ( 199) 317 78.0 2.7e-14
XP_016879167 (OMIM: 611917) PREDICTED: lysine-spec ( 199) 317 78.0 2.7e-14
XP_016879168 (OMIM: 611917) PREDICTED: lysine-spec ( 199) 317 78.0 2.7e-14
NP_079049 (OMIM: 611917) lysine-specific demethyla ( 416) 317 78.1 5.2e-14
XP_011538242 (OMIM: 606615) PREDICTED: hypoxia-ind ( 369) 316 77.9 5.4e-14
NP_001138820 (OMIM: 611917) lysine-specific demeth ( 454) 317 78.2 5.6e-14
XP_011538243 (OMIM: 606615) PREDICTED: hypoxia-ind ( 242) 285 71.1 4e-12
XP_016879165 (OMIM: 611917) PREDICTED: lysine-spec ( 385) 196 51.9 3.9e-06
NP_055982 (OMIM: 604914) bifunctional arginine dem ( 403) 175 47.3 9.5e-05
NP_001074930 (OMIM: 604914) bifunctional arginine ( 414) 175 47.3 9.7e-05
>>NP_078886 (OMIM: 608263) HSPB1-associated protein 1 is (488 aa)
initn: 3364 init1: 3364 opt: 3364 Z-score: 3944.8 bits: 739.4 E(85289): 5.4e-213
Smith-Waterman score: 3364; 100.0% identity (100.0% similar) in 488 aa overlap (1-488:1-488)
10 20 30 40 50 60
pF1KE1 MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 SKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 CNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 PQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 DGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQ
430 440 450 460 470 480
pF1KE1 LLIQGRSL
::::::::
NP_078 LLIQGRSL
>>XP_011511432 (OMIM: 608263) PREDICTED: HSPB1-associate (451 aa)
initn: 3129 init1: 3129 opt: 3129 Z-score: 3669.8 bits: 688.4 E(85289): 1.1e-197
Smith-Waterman score: 3129; 100.0% identity (100.0% similar) in 451 aa overlap (38-488:1-451)
10 20 30 40 50 60
pF1KE1 TTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAKYLSQVL
::::::::::::::::::::::::::::::
XP_011 MSLQQPAIFCNMVFDWPARHWNAKYLSQVL
10 20 30
70 80 90 100 110 120
pF1KE1 HGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHSKFWAYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDHSKFWAYA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 DYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYGCNLVFQV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 QGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHAVTLSPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHAVTLSPGQ
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 VLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAW
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 LNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 GQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGK
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 LHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQGRS
400 410 420 430 440 450
pF1KE1 L
:
XP_011 L
>>XP_011511434 (OMIM: 608263) PREDICTED: HSPB1-associate (449 aa)
initn: 2806 init1: 2806 opt: 2806 Z-score: 3291.0 bits: 618.3 E(85289): 1.4e-176
Smith-Waterman score: 2806; 99.8% identity (100.0% similar) in 407 aa overlap (82-488:43-449)
60 70 80 90 100 110
pF1KE1 DWPARHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSI
.:::::::::::::::::::::::::::::
XP_011 LECGDTISTHCSLNLQGSSDPPASAARVAATTVPQFETTCNYVEATLEEFLTWNCDQSSI
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE1 SGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAH
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE1 TPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFP
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE1 QFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRML
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE1 VCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDG
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE1 EHMKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHMKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFG
320 330 340 350 360 370
420 430 440 450 460 470
pF1KE1 SDGKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVN
380 390 400 410 420 430
480
pF1KE1 PQVTRIVAQLLIQGRSL
:::::::::::::::::
XP_011 PQVTRIVAQLLIQGRSL
440
>>XP_016862668 (OMIM: 608263) PREDICTED: HSPB1-associate (426 aa)
initn: 2912 init1: 2799 opt: 2799 Z-score: 3283.1 bits: 616.7 E(85289): 3.9e-176
Smith-Waterman score: 2799; 100.0% identity (100.0% similar) in 405 aa overlap (84-488:22-426)
60 70 80 90 100 110
pF1KE1 PARHWNAKYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISG
::::::::::::::::::::::::::::::
XP_016 MAAGSEATTPVIVAAGAGGEEVPQFETTCNYVEATLEEFLTWNCDQSSISG
10 20 30 40 50
120 130 140 150 160 170
pF1KE1 PFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTP
60 70 80 90 100 110
180 190 200 210 220 230
pF1KE1 CHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQF
120 130 140 150 160 170
240 250 260 270 280 290
pF1KE1 RKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVC
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE1 ALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEH
240 250 260 270 280 290
360 370 380 390 400 410
pF1KE1 MKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKKEELNVCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSD
300 310 320 330 340 350
420 430 440 450 460 470
pF1KE1 GKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKDFVDKDGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQ
360 370 380 390 400 410
480
pF1KE1 VTRIVAQLLIQGRSL
:::::::::::::::
XP_016 VTRIVAQLLIQGRSL
420
>>XP_005247819 (OMIM: 608263) PREDICTED: HSPB1-associate (280 aa)
initn: 1754 init1: 1754 opt: 1761 Z-score: 2068.6 bits: 391.4 E(85289): 1.7e-108
Smith-Waterman score: 1761; 98.4% identity (98.8% similar) in 255 aa overlap (1-255:1-253)
10 20 30 40 50 60
pF1KE1 MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAEN
::::::::: :.:
XP_005 VTLSPGQVL--ERKWQEGTQLLLLVKRRMDFGGRQSTRVIFI
250 260 270 280
>>NP_001307657 (OMIM: 608263) HSPB1-associated protein 1 (460 aa)
initn: 3145 init1: 1744 opt: 1744 Z-score: 2045.4 bits: 387.8 E(85289): 3.4e-107
Smith-Waterman score: 3093; 94.3% identity (94.3% similar) in 488 aa overlap (1-488:1-460)
10 20 30 40 50 60
pF1KE1 MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYLSQVLHGKQIRFRMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSISGPFRDYDH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTLWIGSLGAHTPCHLDSYG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 CNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHLARVEEAITRMLVCALKTAEN
::::::: :::::::::::::::::::::::::
NP_001 VTLSPGQ----------------------------EEDHLARVEEAITRMLVCALKTAEN
250 260 270
310 320 330 340 350 360
pF1KE1 PQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELN
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 VCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCNHMEVGQTGSQNLTTGTDKPEAASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDK
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 DGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEHFGKLHCAKRQQIMSNSENAIEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQ
400 410 420 430 440 450
pF1KE1 LLIQGRSL
::::::::
NP_001 LLIQGRSL
460
>>XP_016862669 (OMIM: 608263) PREDICTED: HSPB1-associate (253 aa)
initn: 1620 init1: 1620 opt: 1622 Z-score: 1906.3 bits: 361.2 E(85289): 1.9e-99
Smith-Waterman score: 1622; 95.7% identity (96.9% similar) in 255 aa overlap (234-488:4-253)
210 220 230 240 250 260
pF1KE1 LYPTRIPYEESSVFSKINVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESID
: . .: .: ::::::::::::::::
XP_016 MGTRASLEHLIT-----VLFVPRHWWHYVESID
10 20
270 280 290 300 310 320
pF1KE1 PVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTVSINSWIELEEDHLARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCC
30 40 50 60 70 80
330 340 350 360 370 380
pF1KE1 YLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEVGQTGSQNLTTGTDKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLNAAVSAFFDRCRTSEVVEIQALRTDGEHMKKEELNVCNHMEVGQTGSQNLTTGTDKPE
90 100 110 120 130 140
390 400 410 420 430 440
pF1KE1 AASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGKLHCAKRQQIMSNSENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AASPFGPDLVPVAQRSEEPPSERGGIFGSDGKDFVDKDGEHFGKLHCAKRQQIMSNSENA
150 160 170 180 190 200
450 460 470 480
pF1KE1 IEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQGRSL
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEEQIASNTTTTPQTFISTDDLLDCLVNPQVTRIVAQLLIQGRSL
210 220 230 240 250
>>NP_060372 (OMIM: 606615) hypoxia-inducible factor 1-al (349 aa)
initn: 311 init1: 160 opt: 325 Z-score: 383.1 bits: 79.8 E(85289): 1.3e-14
Smith-Waterman score: 329; 27.0% identity (55.3% similar) in 300 aa overlap (32-309:51-341)
10 20 30 40 50 60
pF1KE1 AAGSEATTPVIVAAGAGGEEGEHVKPFKPEKAKEIIMSLQQPAIFCNMVFDWPARHWNAK
.:.:.: . ..:... . . .:: .:. .
NP_060 GALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIEN-EEPVVLTDTNLVYPALKWDLE
30 40 50 60 70
70 80 90 100 110
pF1KE1 YLSQ--------VLHGKQIRF-RMGMKSMSTVPQFETTCNYVEATLEEFLTWNCDQSSIS
::.. : .. .: . :.:.. .:. : : ..::. : .. .
NP_060 YLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRG
80 90 100 110 120 130
120 130 140 150 160
pF1KE1 GPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRN-GQEST--LWIGSLG
: : : .. . . : ... : . .: . :. :: .. : :: :
NP_060 GEERLYLQQTLNDTVGRKIVMDF------LGFNWNWINKQQGKRGWGQLTSNLLLIGMEG
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE1 AHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKINVVNPDLKR
:: : : :. :..: :: ::::.. ::: . .. . :... ::: .:
NP_060 NVTPAHYDEQQ-NFFAQIKGYKRCILFPPDQFECLYPYPV-HHPCDRQSQVDFDNPDYER
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE1 FPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESI--DPVTVSINSWIE-------LEEDHL
::.:... . ....::.::..: .:::..::. .:...: : . .:
NP_060 FPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLK
260 270 280 290 300 310
290 300 310 320 330
pF1KE1 ARVEEAITRMLVCALKTAE-NPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTS
:. . :: : . : : :::.. ::
NP_060 AHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
320 330 340
>>XP_016879169 (OMIM: 611917) PREDICTED: lysine-specific (164 aa)
initn: 237 init1: 172 opt: 317 Z-score: 378.8 bits: 78.0 E(85289): 2.3e-14
Smith-Waterman score: 317; 35.9% identity (65.5% similar) in 142 aa overlap (135-272:26-162)
110 120 130 140 150 160
pF1KE1 NCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTL-
::.. .: ::.. :. : .:.: .
XP_016 MTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLG-DGEEEEIT
10 20 30 40 50
170 180 190 200 210 220
pF1KE1 ---WIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKI
:.: :. .: : : :.. ::.::: .:. :... ::: ... :..
XP_016 INAWFGPQGTISPLHQDPQQ-NFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNT--SQV
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE1 NVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHL
.: ::::..::.: :: . ::::..::.: ..::::...: .. :.. :
XP_016 DVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALD-LSFSVSFWWS
120 130 140 150 160
290 300 310 320 330 340
pF1KE1 ARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSE
>>XP_016879166 (OMIM: 611917) PREDICTED: lysine-specific (199 aa)
initn: 237 init1: 172 opt: 317 Z-score: 377.5 bits: 78.0 E(85289): 2.7e-14
Smith-Waterman score: 317; 35.9% identity (65.5% similar) in 142 aa overlap (135-272:61-197)
110 120 130 140 150 160
pF1KE1 NCDQSSISGPFRDYDHSKFWAYADYKYFVSLFEDKTDLFQDVKWSDFGFPGRNGQESTL-
::.. .: ::.. :. : .:.: .
XP_016 WSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLG-DGEEEEIT
40 50 60 70 80
170 180 190 200 210 220
pF1KE1 ---WIGSLGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFSKI
:.: :. .: : : :.. ::.::: .:. :... ::: ... :..
XP_016 INAWFGPQGTISPLHQDPQQ-NFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNT--SQV
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE1 NVVNPDLKRFPQFRKAQRHAVTLSPGQVLFVPRHWWHYVESIDPVTVSINSWIELEEDHL
.: ::::..::.: :: . ::::..::.: ..::::...: .. :.. :
XP_016 DVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALD-LSFSVSFWWS
150 160 170 180 190
290 300 310 320 330 340
pF1KE1 ARVEEAITRMLVCALKTAENPQNTRAWLNPTEVEETSHAVNCCYLNAAVSAFFDRCRTSE
488 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:47:31 2016 done: Mon Nov 7 01:47:32 2016
Total Scan time: 9.090 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]