Result of FASTA (omim) for
pFN21AE1149
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1149, 449 aa
1>>>pF1KE1149 449 - 449 aa - 449 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9985+/-0.000352; mu= 19.6532+/- 0.022
mean_var=68.9457+/-14.124, 0's: 0 Z-trim(113.7): 13 B-trim: 655 in 1/51
Lambda= 0.154462
statistics sampled from 23165 (23177) to 23165 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.272), width: 16
Scan time: 7.160
The best scores are: opt bits E(85289)
NP_079136 (OMIM: 616424) N-lysine methyltransferas ( 449) 2996 676.8 3.2e-194
NP_001153777 (OMIM: 616424) N-lysine methyltransfe ( 473) 2723 616.0 6.8e-176
XP_011521638 (OMIM: 616424) PREDICTED: N-lysine me ( 272) 1344 308.5 1.4e-83
XP_016877188 (OMIM: 615671) PREDICTED: histone-lys ( 594) 275 70.5 1.3e-11
XP_011535533 (OMIM: 615671) PREDICTED: histone-lys ( 594) 275 70.5 1.3e-11
XP_011535534 (OMIM: 615671) PREDICTED: histone-lys ( 594) 275 70.5 1.3e-11
NP_115609 (OMIM: 615671) histone-lysine N-methyltr ( 594) 275 70.5 1.3e-11
XP_016877189 (OMIM: 615671) PREDICTED: histone-lys ( 594) 275 70.5 1.3e-11
XP_005268184 (OMIM: 615671) PREDICTED: histone-lys ( 495) 246 64.0 1e-09
XP_011535536 (OMIM: 615671) PREDICTED: histone-lys ( 495) 246 64.0 1e-09
>>NP_079136 (OMIM: 616424) N-lysine methyltransferase SE (449 aa)
initn: 2996 init1: 2996 opt: 2996 Z-score: 3607.9 bits: 676.8 E(85289): 3.2e-194
Smith-Waterman score: 2996; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449)
10 20 30 40 50 60
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSRQGTVAGYGMVARESVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSRQGTVAGYGMVARESVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AGELLFVVPRAALLSQHTCSIGGLLERERVALQSQSGWVPLLLALLHELQAPASRWRPYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AGELLFVVPRAALLSQHTCSIGGLLERERVALQSQSGWVPLLLALLHELQAPASRWRPYF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPVMVPAADILNHLANHNANLEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPVMVPAADILNHLANHNANLEYSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 NCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFREL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 KDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVY
370 380 390 400 410 420
430 440
pF1KE1 AKLSWREQQALQVRYGQKMILHQLLELTS
:::::::::::::::::::::::::::::
NP_079 AKLSWREQQALQVRYGQKMILHQLLELTS
430 440
>>NP_001153777 (OMIM: 616424) N-lysine methyltransferase (473 aa)
initn: 2718 init1: 2718 opt: 2723 Z-score: 3278.8 bits: 616.0 E(85289): 6.8e-176
Smith-Waterman score: 2938; 94.9% identity (94.9% similar) in 473 aa overlap (1-449:1-473)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKV--------------------
::::::::::::::::::::::::::::::::::::::::
NP_001 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVSERAGGRRTRGGARAALTSP
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 ----AVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAQVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 GWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 LANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 PVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 EPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGREE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 VLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGSLTITNIPKLKASWRQLLQNSV
370 380 390 400 410 420
400 410 420 430 440
pF1KE1 LLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
430 440 450 460 470
>>XP_011521638 (OMIM: 616424) PREDICTED: N-lysine methyl (272 aa)
initn: 1339 init1: 1339 opt: 1344 Z-score: 1621.4 bits: 308.5 E(85289): 1.4e-83
Smith-Waterman score: 1559; 90.9% identity (90.9% similar) in 264 aa overlap (1-240:1-264)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKV--------------------
::::::::::::::::::::::::::::::::::::::::
XP_011 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVSERAGGRRTRGGARAALTSP
10 20 30 40 50 60
50 60 70 80 90
pF1KE1 ----AVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAQVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALLSQHTCSIGGLLERERVALQSQS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 GWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 LANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LANIRSEYQSIVLPFMEAHPDLFSLRVRSLELYHQLVALVMAYSFQEPLEEEEDEKEPNS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 PVMVPAADILNHLANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGFV
::::::::::::::::::::::::
XP_011 PVMVPAADILNHLANHNANLEYSAMTQLTFRW
250 260 270
>>XP_016877188 (OMIM: 615671) PREDICTED: histone-lysine (594 aa)
initn: 85 init1: 59 opt: 275 Z-score: 329.2 bits: 70.5 E(85289): 1.3e-11
Smith-Waterman score: 369; 25.9% identity (53.6% similar) in 440 aa overlap (15-443:72-477)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSR
:: : ...: . : . :.
XP_016 GPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNF
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE1 QGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGGLLERERVALQSQSGWVPL
. :.:. : ....: ::.. ::: :. : .. .: : ..:. ::.. : . :
XP_016 KEE--GFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRI-LQAM-GNIAL
110 120 130 140 150
110 120 130 140 150 160
pF1KE1 LLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIR
. :: : .: : :.::. : .. . :... :.: : ::.: . . : .. :
XP_016 AFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-YLQSTQAIHDVFSQYKNTA
160 170 180 190 200 210
170 180 190 200 210
pF1KE1 SEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPV
.: . ...:: .: .. . : :. :. ::. . : : :. . .
XP_016 RQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSR----VTLA
220 230 240 250 260
220 230 240 250 260 270
pF1KE1 MVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGF
..: :. :: : . . ::: . : . :: : . :..:. :: .: ... ::
XP_016 LIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQIYIFYGTRSNAEFVIHSGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 VEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGRE
. .:. : . :.. . . : . :.: : : . ..:..
XP_016 F--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR-------AGIPTSSVFALHFT
330 340 350 360 370
340 350 360 370 380 390
pF1KE1 EVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--LTITNIPKLKASWRQLLQ
: .: . :.:.:: ::..: :.. : :. . .. ..: : .:.
XP_016 EPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKL-WT-FLE
380 390 400 410 420 430
400 410 420 430 440
pF1KE1 NSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
. . : :.:: : .. :...:.:.. :: : ..:...: :.: ::..
XP_016 DRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRLGEKEILEKAVKSAAVNRE
440 450 460 470 480
XP_016 YYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKA
490 500 510 520 530 540
>>XP_011535533 (OMIM: 615671) PREDICTED: histone-lysine (594 aa)
initn: 85 init1: 59 opt: 275 Z-score: 329.2 bits: 70.5 E(85289): 1.3e-11
Smith-Waterman score: 369; 25.9% identity (53.6% similar) in 440 aa overlap (15-443:72-477)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSR
:: : ...: . : . :.
XP_011 GPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNF
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE1 QGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGGLLERERVALQSQSGWVPL
. :.:. : ....: ::.. ::: :. : .. .: : ..:. ::.. : . :
XP_011 KEE--GFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRI-LQAM-GNIAL
110 120 130 140 150
110 120 130 140 150 160
pF1KE1 LLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIR
. :: : .: : :.::. : .. . :... :.: : ::.: . . : .. :
XP_011 AFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-YLQSTQAIHDVFSQYKNTA
160 170 180 190 200 210
170 180 190 200 210
pF1KE1 SEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPV
.: . ...:: .: .. . : :. :. ::. . : : :. . .
XP_011 RQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSR----VTLA
220 230 240 250 260
220 230 240 250 260 270
pF1KE1 MVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGF
..: :. :: : . . ::: . : . :: : . :..:. :: .: ... ::
XP_011 LIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQIYIFYGTRSNAEFVIHSGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 VEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGRE
. .:. : . :.. . . : . :.: : : . ..:..
XP_011 F--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR-------AGIPTSSVFALHFT
330 340 350 360 370
340 350 360 370 380 390
pF1KE1 EVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--LTITNIPKLKASWRQLLQ
: .: . :.:.:: ::..: :.. : :. . .. ..: : .:.
XP_011 EPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKL-WT-FLE
380 390 400 410 420 430
400 410 420 430 440
pF1KE1 NSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
. . : :.:: : .. :...:.:.. :: : ..:...: :.: ::..
XP_011 DRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRLGEKEILEKAVKSAAVNRE
440 450 460 470 480
XP_011 YYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKA
490 500 510 520 530 540
>>XP_011535534 (OMIM: 615671) PREDICTED: histone-lysine (594 aa)
initn: 85 init1: 59 opt: 275 Z-score: 329.2 bits: 70.5 E(85289): 1.3e-11
Smith-Waterman score: 369; 25.9% identity (53.6% similar) in 440 aa overlap (15-443:72-477)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSR
:: : ...: . : . :.
XP_011 GPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNF
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE1 QGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGGLLERERVALQSQSGWVPL
. :.:. : ....: ::.. ::: :. : .. .: : ..:. ::.. : . :
XP_011 KEE--GFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRI-LQAM-GNIAL
110 120 130 140 150
110 120 130 140 150 160
pF1KE1 LLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIR
. :: : .: : :.::. : .. . :... :.: : ::.: . . : .. :
XP_011 AFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-YLQSTQAIHDVFSQYKNTA
160 170 180 190 200 210
170 180 190 200 210
pF1KE1 SEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPV
.: . ...:: .: .. . : :. :. ::. . : : :. . .
XP_011 RQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSR----VTLA
220 230 240 250 260
220 230 240 250 260 270
pF1KE1 MVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGF
..: :. :: : . . ::: . : . :: : . :..:. :: .: ... ::
XP_011 LIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQIYIFYGTRSNAEFVIHSGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 VEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGRE
. .:. : . :.. . . : . :.: : : . ..:..
XP_011 F--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR-------AGIPTSSVFALHFT
330 340 350 360 370
340 350 360 370 380 390
pF1KE1 EVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--LTITNIPKLKASWRQLLQ
: .: . :.:.:: ::..: :.. : :. . .. ..: : .:.
XP_011 EPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKL-WT-FLE
380 390 400 410 420 430
400 410 420 430 440
pF1KE1 NSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
. . : :.:: : .. :...:.:.. :: : ..:...: :.: ::..
XP_011 DRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRLGEKEILEKAVKSAAVNRE
440 450 460 470 480
XP_011 YYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKA
490 500 510 520 530 540
>>NP_115609 (OMIM: 615671) histone-lysine N-methyltransf (594 aa)
initn: 85 init1: 59 opt: 275 Z-score: 329.2 bits: 70.5 E(85289): 1.3e-11
Smith-Waterman score: 369; 25.9% identity (53.6% similar) in 440 aa overlap (15-443:72-477)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSR
:: : ...: . : . :.
NP_115 GPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNF
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE1 QGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGGLLERERVALQSQSGWVPL
. :.:. : ....: ::.. ::: :. : .. .: : ..:. ::.. : . :
NP_115 KEE--GFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRI-LQAM-GNIAL
110 120 130 140 150
110 120 130 140 150 160
pF1KE1 LLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIR
. :: : .: : :.::. : .. . :... :.: : ::.: . . : .. :
NP_115 AFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-YLQSTQAIHDVFSQYKNTA
160 170 180 190 200 210
170 180 190 200 210
pF1KE1 SEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPV
.: . ...:: .: .. . : :. :. ::. . : : :. . .
NP_115 RQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSR----VTLA
220 230 240 250 260
220 230 240 250 260 270
pF1KE1 MVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGF
..: :. :: : . . ::: . : . :: : . :..:. :: .: ... ::
NP_115 LIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQIYIFYGTRSNAEFVIHSGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 VEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGRE
. .:. : . :.. . . : . :.: : : . ..:..
NP_115 F--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR-------AGIPTSSVFALHFT
330 340 350 360 370
340 350 360 370 380 390
pF1KE1 EVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--LTITNIPKLKASWRQLLQ
: .: . :.:.:: ::..: :.. : :. . .. ..: : .:.
NP_115 EPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKL-WT-FLE
380 390 400 410 420 430
400 410 420 430 440
pF1KE1 NSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
. . : :.:: : .. :...:.:.. :: : ..:...: :.: ::..
NP_115 DRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRLGEKEILEKAVKSAAVNRE
440 450 460 470 480
NP_115 YYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKA
490 500 510 520 530 540
>>XP_016877189 (OMIM: 615671) PREDICTED: histone-lysine (594 aa)
initn: 85 init1: 59 opt: 275 Z-score: 329.2 bits: 70.5 E(85289): 1.3e-11
Smith-Waterman score: 369; 25.9% identity (53.6% similar) in 440 aa overlap (15-443:72-477)
10 20 30 40
pF1KE1 MATQAKRPRVAGPVDGGDLDPVACFLSWCRRVGLELSPKVAVSR
:: : ...: . : . :.
XP_016 GPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNF
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE1 QGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGGLLERERVALQSQSGWVPL
. :.:. : ....: ::.. ::: :. : .. .: : ..:. ::.. : . :
XP_016 KEE--GFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRI-LQAM-GNIAL
110 120 130 140 150
110 120 130 140 150 160
pF1KE1 LLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCLLQGTGVPEAVEKDLANIR
. :: : .: : :.::. : .. . :... :.: : ::.: . . : .. :
XP_016 AFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-YLQSTQAIHDVFSQYKNTA
160 170 180 190 200 210
170 180 190 200 210
pF1KE1 SEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYSFQEPLEEEEDEKEPNSPV
.: . ...:: .: .. . : :. :. ::. . : : :. . .
XP_016 RQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSR----VTLA
220 230 240 250 260
220 230 240 250 260 270
pF1KE1 MVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEIFNTYGQMANWQLIHMYGF
..: :. :: : . . ::: . : . :: : . :..:. :: .: ... ::
XP_016 LIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQIYIFYGTRSNAEFVIHSGF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 VEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDFLCKLEMVGEEGAFVIGRE
. .:. : . :.. . . : . :.: : : . ..:..
XP_016 F--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR-------AGIPTSSVFALHFT
330 340 350 360 370
340 350 360 370 380 390
pF1KE1 EVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--LTITNIPKLKASWRQLLQ
: .: . :.:.:: ::..: :.. : :. . .. ..: : .:.
XP_016 EPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKL-WT-FLE
380 390 400 410 420 430
400 410 420 430 440
pF1KE1 NSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRYGQKMILHQLLELTS
. . : :.:: : .. :...:.:.. :: : ..:...: :.: ::..
XP_016 DRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRLGEKEILEKAVKSAAVNRE
440 450 460 470 480
XP_016 YYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKA
490 500 510 520 530 540
>>XP_005268184 (OMIM: 615671) PREDICTED: histone-lysine (495 aa)
initn: 135 init1: 59 opt: 246 Z-score: 295.4 bits: 64.0 E(85289): 1e-09
Smith-Waterman score: 340; 26.6% identity (54.5% similar) in 398 aa overlap (57-443:13-378)
30 40 50 60 70 80
pF1KE1 SWCRRVGLELSPKVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGG
.: .: ::.. ::: :. : .. .:
XP_005 MCRSGLWLRKYGKSKKAEELFLWVPRKLLMTVESAKNSVLGP
10 20 30 40
90 100 110 120 130 140
pF1KE1 LLERERVALQSQSGWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCL
: ..:. ::.. : . : . :: : .: : :.::. : .. . :... :.: :
XP_005 LYSQDRI-LQAM-GNIALAFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-Y
50 60 70 80 90
150 160 170 180 190 200
pF1KE1 LQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYS
::.: . . : .. : .: . ...:: .: .. . : :. :. ::. .
XP_005 LQSTQAIHDVFSQYKNTARQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQ
100 110 120 130 140 150
210 220 230 240 250
pF1KE1 FQEPLEEEEDEKEPNSPVMVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEI
: : :. . ...: :. :: : . . ::: . : . :: : . :..:
XP_005 NQIPTED----GSRVTLALIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQI
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 FNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDF
. :: .: ... :: . .:. : . :.. . . : . :.: : :
XP_005 YIFYGTRSNAEFVIHSGFF--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR---
220 230 240 250 260
320 330 340 350 360 370
pF1KE1 LCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--
. ..:.. : .: . :.:.:: ::..: :.. : :.
XP_005 ----AGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSE
270 280 290 300 310
380 390 400 410 420 430
pF1KE1 LTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRY
. .. ..: : .:.. . : :.:: : .. :...:.:.. :: : ..:...:
XP_005 FPVSWDNEVKL-WT-FLEDRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRL
320 330 340 350 360 370
440
pF1KE1 GQKMILHQLLELTS
:.: ::..
XP_005 GEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEE
380 390 400 410 420 430
>>XP_011535536 (OMIM: 615671) PREDICTED: histone-lysine (495 aa)
initn: 135 init1: 59 opt: 246 Z-score: 295.4 bits: 64.0 E(85289): 1e-09
Smith-Waterman score: 340; 26.6% identity (54.5% similar) in 398 aa overlap (57-443:13-378)
30 40 50 60 70 80
pF1KE1 SWCRRVGLELSPKVAVSRQGTVAGYGMVARESVQAGELLFVVPRAALL---SQHTCSIGG
.: .: ::.. ::: :. : .. .:
XP_011 MCRSGLWLRKYGKSKKAEELFLWVPRKLLMTVESAKNSVLGP
10 20 30 40
90 100 110 120 130 140
pF1KE1 LLERERVALQSQSGWVPLLLALLHELQAPASRWRPYFALWPELGRLEHPMFWPEEERRCL
: ..:. ::.. : . : . :: : .: : :.::. : .. . :... :.: :
XP_011 LYSQDRI-LQAM-GNIALAFHLLCERASPNSFWQPYIQTLP--SEYDTPLYFEEDEVR-Y
50 60 70 80 90
150 160 170 180 190 200
pF1KE1 LQGTGVPEAVEKDLANIRSEYQSIVLPFMEAHPDLFSLRVR---SLELYHQLVALVMAYS
::.: . . : .. : .: . ...:: .: .. . : :. :. ::. .
XP_011 LQSTQAIHDVFSQYKNTARQY-AYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQ
100 110 120 130 140 150
210 220 230 240 250
pF1KE1 FQEPLEEEEDEKEPNSPVMVPAADILNH---LANHNANLEYSANCLRMVATQPIPKGHEI
: : :. . ...: :. :: : . . ::: . : . :: : . :..:
XP_011 NQIPTED----GSRVTLALIPLWDMCNHTNGLITTGYNLE-DDRC-ECVALQDFRAGEQI
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE1 FNTYGQMANWQLIHMYGFVEPYPDNTDDTADIQMVTVREAALQGTKTEAERHLVYERWDF
. :: .: ... :: . .:. : . :.. . . : . :.: : :
XP_011 YIFYGTRSNAEFVIHSGFF--FDNNSHDRVKIKLGVSKSDRLYAMKAE-----VLAR---
220 230 240 250 260
320 330 340 350 360 370
pF1KE1 LCKLEMVGEEGAFVIGREEVLTEEELTTTLKVLCMPAEEFRELKDQDGGGDDKREEGS--
. ..:.. : .: . :.:.:: ::..: :.. : :.
XP_011 ----AGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSE
270 280 290 300 310
380 390 400 410 420 430
pF1KE1 LTITNIPKLKASWRQLLQNSVLLTLQTYATDLKTDQGLLSNKEVYAKLSWREQQALQVRY
. .. ..: : .:.. . : :.:: : .. :...:.:.. :: : ..:...:
XP_011 FPVSWDNEVKL-WT-FLEDRASLLLKTYKTTIEEDKSVLKNHD----LSVRAKMAIKLRL
320 330 340 350 360 370
440
pF1KE1 GQKMILHQLLELTS
:.: ::..
XP_011 GEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEE
380 390 400 410 420 430
449 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:04:46 2016 done: Sun Nov 6 14:04:47 2016
Total Scan time: 7.160 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]