Result of FASTA (ccds) for
pFN21AE1148
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1148, 462 aa
1>>>pF1KE1148 462 - 462 aa - 462 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5684+/-0.000716; mu= 14.8056+/- 0.044
mean_var=142.2813+/-27.897, 0's: 0 Z-trim(114.9): 18 B-trim: 3 in 1/53
Lambda= 0.107523
statistics sampled from 15403 (15415) to 15403 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.474), width: 16
Scan time: 3.690
The best scores are: opt bits E(32554)
CCDS12922.1 KMT5C gene_id:84787|Hs108|chr19 ( 462) 3289 521.3 8.4e-148
CCDS76444.1 KMT5B gene_id:51111|Hs108|chr11 ( 370) 1152 189.7 4.4e-48
CCDS44660.1 KMT5B gene_id:51111|Hs108|chr11 ( 393) 983 163.5 3.6e-40
CCDS31623.1 KMT5B gene_id:51111|Hs108|chr11 ( 885) 983 163.8 6.4e-40
>>CCDS12922.1 KMT5C gene_id:84787|Hs108|chr19 (462 aa)
initn: 3289 init1: 3289 opt: 3289 Z-score: 2767.0 bits: 521.3 E(32554): 8.4e-148
Smith-Waterman score: 3289; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE1 MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMNVSPVPPLRRQQHLRSALETFLRQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMNVSPVPPLRRQQHLRSALETFLRQRD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LEAAYRALTLGGWTARYFQSRGPRQEAALKTHVYRYLRAFLPESGFTILPCTRYSMETNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LEAAYRALTLGGWTARYFQSRGPRQEAALKTHVYRYLRAFLPESGFTILPCTRYSMETNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AKIVSTRAWKKNEKLELLVGCIAELREADEGLLRAGENDFSIMYSTRKRSAQLWLGPAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AKIVSTRAWKKNEKLELLVGCIAELREADEGLLRAGENDFSIMYSTRKRSAQLWLGPAAF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 INHDCKPNCKFVPADGNAACVKVLRDIEPGDEVTCFYGEGFFGEKNEHCECHTCERKGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 INHDCKPNCKFVPADGNAACVKVLRDIEPGDEVTCFYGEGFFGEKNEHCECHTCERKGEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AFRTRPREPALPPRPLDKYQLRETKRRLQQGLDSGSRQGLLGPRACVHPSPLRRDPFCAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AFRTRPREPALPPRPLDKYQLRETKRRLQQGLDSGSRQGLLGPRACVHPSPLRRDPFCAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CQPLRLPACSARPDTSPLWLQWLPQPQPRVRPRKRRRPRPRRAPVLSTHHAARVSLHRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 CQPLRLPACSARPDTSPLWLQWLPQPQPRVRPRKRRRPRPRRAPVLSTHHAARVSLHRWG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GCGPHCRLRGEALVALGQPPHARWAPQQDWHWARRYGLPYVVRVDLRRLAPAPPATPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GCGPHCRLRGEALVALGQPPHARWAPQQDWHWARRYGLPYVVRVDLRRLAPAPPATPAPA
370 380 390 400 410 420
430 440 450 460
pF1KE1 GTPGPILIPKQALAFAPFSPPKRLRLVVSHGSIDLDVGGEEL
::::::::::::::::::::::::::::::::::::::::::
CCDS12 GTPGPILIPKQALAFAPFSPPKRLRLVVSHGSIDLDVGGEEL
430 440 450 460
>>CCDS76444.1 KMT5B gene_id:51111|Hs108|chr11 (370 aa)
initn: 1147 init1: 598 opt: 1152 Z-score: 976.6 bits: 189.7 E(32554): 4.4e-48
Smith-Waterman score: 1152; 62.0% identity (81.2% similar) in 266 aa overlap (6-270:72-337)
10 20 30
pF1KE1 MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMN
..:.::::::::::::::::::::.:::::
CCDS76 AGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMN
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE1 VSPVPPLRRQQHLRSALETFLRQRDLEAAYRALTLGGWTARYFQSRGPRQEAALKTHVYR
. : ::..:. ..: : ... :: :.. :: : :. .:: ... :: .: ::.
CCDS76 TRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFI
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE1 YLRAFLPESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLELLVGCIAELREADEG-LLR
::: : .::: ::::.::: : ::::::.:. ::.:.:.:::::::::: : .:. :::
CCDS76 YLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLR
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE1 AGENDFSIMYSTRKRSAQLWLGPAAFINHDCKPNCKFVPADGNAACVKVLRDIEPGDEVT
::::::.:::::: :::::::::::::::.:::::: . ..::::.:::::::.:..
CCDS76 HGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEIS
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE1 CFYGEGFFGEKNEHCECHTCERKGEGAFRTRPREPALPPRPLDKYQLRETKRRLQQGLDS
:.::.:::::.:: :::.::::.: :::..: :: : .:: :::: .::..
CCDS76 CYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKL
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE1 GSRQGLLGPRACVHPSPLRRDPFCAACQPLRLPACSARPDTSPLWLQWLPQPQPRVRPRK
CCDS76 GDSSKNSDSQSVSSNTDADTTQEKNNASK
350 360 370
>>CCDS44660.1 KMT5B gene_id:51111|Hs108|chr11 (393 aa)
initn: 1164 init1: 598 opt: 983 Z-score: 834.6 bits: 163.5 E(32554): 3.6e-40
Smith-Waterman score: 1124; 58.1% identity (76.1% similar) in 289 aa overlap (6-270:72-360)
10 20 30
pF1KE1 MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMN
..:.::::::::::::::::::::.:::::
CCDS44 AGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMN
50 60 70 80 90 100
40 50 60 70
pF1KE1 VSPVP-----------------PLR------RQQHLRSALETFLRQRDLEAAYRALTLGG
.: : :.: ::..:. ..: : ... :: :.. :: :
CCDS44 TSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGE
110 120 130 140 150 160
80 90 100 110 120 130
pF1KE1 WTARYFQSRGPRQEAALKTHVYRYLRAFLPESGFTILPCTRYSMETNGAKIVSTRAWKKN
:. .:: ... :: .: ::. ::: : .::: ::::.::: : ::::::.:. ::.:
CCDS44 WARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRN
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE1 EKLELLVGCIAELREADEG-LLRAGENDFSIMYSTRKRSAQLWLGPAAFINHDCKPNCKF
.:.:::::::::: : .:. ::: ::::::.:::::: :::::::::::::::.:::::
CCDS44 DKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKF
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE1 VPADGNAACVKVLRDIEPGDEVTCFYGEGFFGEKNEHCECHTCERKGEGAFRTRPREPAL
: . ..::::.:::::::.:..:.::.:::::.:: :::.::::.: :::..: ::
CCDS44 VSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAP
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE1 PPRPLDKYQLRETKRRLQQGLDSGSRQGLLGPRACVHPSPLRRDPFCAACQPLRLPACSA
: .:: :::: .::..
CCDS44 APVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNASK
350 360 370 380 390
>>CCDS31623.1 KMT5B gene_id:51111|Hs108|chr11 (885 aa)
initn: 835 init1: 598 opt: 983 Z-score: 830.2 bits: 163.8 E(32554): 6.4e-40
Smith-Waterman score: 1124; 58.1% identity (76.1% similar) in 289 aa overlap (6-270:72-360)
10 20 30
pF1KE1 MGPDRVTARELCENDDLATSLVLDPYLGFRTHKMN
..:.::::::::::::::::::::.:::::
CCDS31 AGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMN
50 60 70 80 90 100
40 50 60 70
pF1KE1 VSPVP-----------------PLR------RQQHLRSALETFLRQRDLEAAYRALTLGG
.: : :.: ::..:. ..: : ... :: :.. :: :
CCDS31 TSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGE
110 120 130 140 150 160
80 90 100 110 120 130
pF1KE1 WTARYFQSRGPRQEAALKTHVYRYLRAFLPESGFTILPCTRYSMETNGAKIVSTRAWKKN
:. .:: ... :: .: ::. ::: : .::: ::::.::: : ::::::.:. ::.:
CCDS31 WARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRN
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE1 EKLELLVGCIAELREADEG-LLRAGENDFSIMYSTRKRSAQLWLGPAAFINHDCKPNCKF
.:.:::::::::: : .:. ::: ::::::.:::::: :::::::::::::::.:::::
CCDS31 DKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKF
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE1 VPADGNAACVKVLRDIEPGDEVTCFYGEGFFGEKNEHCECHTCERKGEGAFRTRPREPAL
: . ..::::.:::::::.:..:.::.:::::.:: :::.::::.: :::..: ::
CCDS31 VSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAP
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE1 PPRPLDKYQLRETKRRLQQGLDSGSRQGLLGPRACVHPSPLRRDPFCAACQPLRLPACSA
: .:: :::: .::..
CCDS31 APVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGV
350 360 370 380 390 400
462 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:13:09 2016 done: Sun Nov 6 13:13:10 2016
Total Scan time: 3.690 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]