Result of FASTA (omim) for
pFN21AE1135
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1135, 353 aa
1>>>pF1KE1135 353 - 353 aa - 353 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9907+/-0.000391; mu= 7.7661+/- 0.024
mean_var=138.4063+/-30.563, 0's: 0 Z-trim(116.8): 247 B-trim: 1259 in 1/52
Lambda= 0.109018
statistics sampled from 27848 (28210) to 27848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.331), width: 16
Scan time: 7.660
The best scores are: opt bits E(85289)
NP_001305407 (OMIM: 608015) tsukushin isoform b pr ( 353) 2343 380.2 3.8e-105
NP_001245139 (OMIM: 608015) tsukushin isoform b pr ( 353) 2343 380.2 3.8e-105
NP_056331 (OMIM: 608015) tsukushin isoform b precu ( 353) 2343 380.2 3.8e-105
NP_001305408 (OMIM: 608015) tsukushin isoform b pr ( 353) 2343 380.2 3.8e-105
NP_001305406 (OMIM: 608015) tsukushin isoform a pr ( 367) 2343 380.2 3.9e-105
XP_005244884 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 337 64.9 6.1e-10
NP_006329 (OMIM: 605492) leucine-rich repeat neuro ( 713) 337 64.9 6.1e-10
XP_016855539 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 337 64.9 6.1e-10
NP_963924 (OMIM: 605492) leucine-rich repeat neuro ( 713) 337 64.9 6.1e-10
XP_011507368 (OMIM: 605492) PREDICTED: leucine-ric ( 713) 337 64.9 6.1e-10
NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560) 293 57.9 6.2e-08
NP_443204 (OMIM: 611289) leucine-rich alpha-2-glyc ( 347) 283 56.2 1.3e-07
NP_004961 (OMIM: 601489,615961) insulin-like growt ( 605) 285 56.7 1.6e-07
NP_001139478 (OMIM: 601489,615961) insulin-like gr ( 643) 285 56.7 1.6e-07
XP_016857485 (OMIM: 606653) PREDICTED: leucine-ric ( 876) 275 55.2 6.2e-07
XP_011508141 (OMIM: 606653) PREDICTED: leucine-ric ( 900) 275 55.3 6.3e-07
NP_001264156 (OMIM: 606667) leucine-rich repeat-co ( 835) 274 55.1 6.6e-07
XP_005273960 (OMIM: 137207) PREDICTED: leucine-ric ( 640) 271 54.5 7.5e-07
XP_011543237 (OMIM: 137207) PREDICTED: leucine-ric ( 662) 271 54.5 7.7e-07
XP_016873016 (OMIM: 137207) PREDICTED: leucine-ric ( 662) 271 54.5 7.7e-07
NP_005503 (OMIM: 137207) leucine-rich repeat-conta ( 662) 271 54.5 7.7e-07
XP_005273959 (OMIM: 137207) PREDICTED: leucine-ric ( 662) 271 54.5 7.7e-07
NP_001122394 (OMIM: 137207) leucine-rich repeat-co ( 662) 271 54.5 7.7e-07
NP_612449 (OMIM: 608843) vasorin precursor [Homo s ( 673) 265 53.6 1.5e-06
XP_011538979 (OMIM: 608661) PREDICTED: podocan iso ( 402) 251 51.2 4.7e-06
NP_060150 (OMIM: 603932,607850,608135) asporin iso ( 379) 250 51.0 5e-06
XP_005270514 (OMIM: 608661) PREDICTED: podocan iso ( 613) 251 51.4 6.4e-06
NP_001186010 (OMIM: 608661) podocan isoform 2 [Hom ( 642) 251 51.4 6.7e-06
NP_001186009 (OMIM: 608661) podocan isoform 2 [Hom ( 642) 251 51.4 6.7e-06
XP_016855783 (OMIM: 608661) PREDICTED: podocan iso ( 652) 251 51.4 6.7e-06
NP_714914 (OMIM: 608661) podocan isoform 1 [Homo s ( 661) 251 51.4 6.8e-06
NP_003658 (OMIM: 606667) leucine-rich repeat-conta ( 907) 249 51.2 1.1e-05
NP_001180264 (OMIM: 603932,607850,608135) asporin ( 242) 234 48.4 2e-05
NP_001264155 (OMIM: 606667) leucine-rich repeat-co ( 883) 238 49.4 3.5e-05
XP_005271426 (OMIM: 608869,615112) PREDICTED: leuc ( 958) 237 49.3 4.2e-05
XP_011542154 (OMIM: 605352) PREDICTED: malignant f (1003) 237 49.3 4.3e-05
NP_004216 (OMIM: 605352) malignant fibrous histioc (1052) 237 49.3 4.5e-05
NP_055628 (OMIM: 608869,615112) leucine-rich repea (1065) 237 49.3 4.5e-05
NP_001255968 (OMIM: 602775,607721) leucine-rich re ( 536) 232 48.3 4.6e-05
NP_001299615 (OMIM: 608869,615112) leucine-rich re ( 962) 236 49.1 4.6e-05
NP_001311266 (OMIM: 602775,607721) leucine-rich re ( 582) 232 48.3 4.9e-05
XP_016872193 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 232 48.3 4.9e-05
XP_016872191 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 232 48.3 4.9e-05
XP_016872192 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 232 48.3 4.9e-05
NP_031399 (OMIM: 602775,607721) leucine-rich repea ( 582) 232 48.3 4.9e-05
NP_001311265 (OMIM: 602775,607721) leucine-rich re ( 582) 232 48.3 4.9e-05
NP_056379 (OMIM: 610868) leucine-rich repeat trans ( 516) 229 47.8 6.2e-05
XP_006719333 (OMIM: 125255,610048) PREDICTED: deco ( 359) 224 46.9 8.1e-05
XP_005268750 (OMIM: 125255,610048) PREDICTED: deco ( 359) 224 46.9 8.1e-05
XP_016874406 (OMIM: 125255,610048) PREDICTED: deco ( 359) 224 46.9 8.1e-05
>>NP_001305407 (OMIM: 608015) tsukushin isoform b precur (353 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2008.7 bits: 380.2 E(85289): 3.8e-105
Smith-Waterman score: 2343; 99.7% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRESAARGPTIL
:::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_001 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL
310 320 330 340 350
>>NP_001245139 (OMIM: 608015) tsukushin isoform b precur (353 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2008.7 bits: 380.2 E(85289): 3.8e-105
Smith-Waterman score: 2343; 99.7% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRESAARGPTIL
:::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_001 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL
310 320 330 340 350
>>NP_056331 (OMIM: 608015) tsukushin isoform b precursor (353 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2008.7 bits: 380.2 E(85289): 3.8e-105
Smith-Waterman score: 2343; 99.7% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRESAARGPTIL
:::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_056 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL
310 320 330 340 350
>>NP_001305408 (OMIM: 608015) tsukushin isoform b precur (353 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2008.7 bits: 380.2 E(85289): 3.8e-105
Smith-Waterman score: 2343; 99.7% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLL
250 260 270 280 290 300
310 320 330 340 350
pF1KE1 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRESAARGPTIL
:::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_001 HLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL
310 320 330 340 350
>>NP_001305406 (OMIM: 608015) tsukushin isoform a precur (367 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 2008.5 bits: 380.2 E(85289): 3.9e-105
Smith-Waterman score: 2343; 99.7% identity (100.0% similar) in 353 aa overlap (1-353:15-367)
10 20 30 40
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSG
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIVRPSTATWNSPTMPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 LGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 LRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 NLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 GLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE1 SGTNLVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRESA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 SGTNLVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSA
310 320 330 340 350 360
350
pF1KE1 ARGPTIL
:::::::
NP_001 ARGPTIL
>>XP_005244884 (OMIM: 605492) PREDICTED: leucine-rich re (713 aa)
initn: 342 init1: 175 opt: 337 Z-score: 299.4 bits: 64.9 E(85289): 6.1e-10
Smith-Waterman score: 377; 33.2% identity (59.3% similar) in 307 aa overlap (19-315:28-322)
10 20 30 40
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVET-FGLFDSFS-LTRVDCSGLGP
:: : : :... . .:. : :::. :
XP_005 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 HIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLR
.: .: : : :.:: . :..: : :: ..:. ::::.: ... : :
XP_005 TAVPPALPAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALP
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHN
: :: : .: :: : .::.. . :... :.:::: ... ::. :. :: :. :
XP_005 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLH--LNSN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 LIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV--PNLRDLP-LRYLSLDGNPLAVIGPGA
:.. . .: :... : .. :.. :. :.: : :: : : : : :. :
XP_005 LLRAI---DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FAGLGGLTHLSL--ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQ
. :: .: ::. .: :.:. : ....:::. :::. :: :. .: :... :.
XP_005 LEGLQSLESLSFYDNQLARVPRRA---LEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLK
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 ELDLSGTN-LVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVD
:: :.. . :: . . :..:: : .... .. :
XP_005 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS
290 300 310 320 330 340
350
pF1KE1 TRESAARGPTIL
XP_005 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV
350 360 370 380 390 400
>>NP_006329 (OMIM: 605492) leucine-rich repeat neuronal (713 aa)
initn: 342 init1: 175 opt: 337 Z-score: 299.4 bits: 64.9 E(85289): 6.1e-10
Smith-Waterman score: 377; 33.2% identity (59.3% similar) in 307 aa overlap (19-315:28-322)
10 20 30 40
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVET-FGLFDSFS-LTRVDCSGLGP
:: : : :... . .:. : :::. :
NP_006 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 HIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLR
.: .: : : :.:: . :..: : :: ..:. ::::.: ... : :
NP_006 TAVPPALPAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALP
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHN
: :: : .: :: : .::.. . :... :.:::: ... ::. :. :: :. :
NP_006 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLH--LNSN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 LIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV--PNLRDLP-LRYLSLDGNPLAVIGPGA
:.. . .: :... : .. :.. :. :.: : :: : : : : :. :
NP_006 LLRAI---DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FAGLGGLTHLSL--ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQ
. :: .: ::. .: :.:. : ....:::. :::. :: :. .: :... :.
NP_006 LEGLQSLESLSFYDNQLARVPRRA---LEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLK
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 ELDLSGTN-LVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVD
:: :.. . :: . . :..:: : .... .. :
NP_006 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS
290 300 310 320 330 340
350
pF1KE1 TRESAARGPTIL
NP_006 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV
350 360 370 380 390 400
>>XP_016855539 (OMIM: 605492) PREDICTED: leucine-rich re (713 aa)
initn: 342 init1: 175 opt: 337 Z-score: 299.4 bits: 64.9 E(85289): 6.1e-10
Smith-Waterman score: 377; 33.2% identity (59.3% similar) in 307 aa overlap (19-315:28-322)
10 20 30 40
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVET-FGLFDSFS-LTRVDCSGLGP
:: : : :... . .:. : :::. :
XP_016 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 HIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLR
.: .: : : :.:: . :..: : :: ..:. ::::.: ... : :
XP_016 TAVPPALPAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALP
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHN
: :: : .: :: : .::.. . :... :.:::: ... ::. :. :: :. :
XP_016 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLH--LNSN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 LIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV--PNLRDLP-LRYLSLDGNPLAVIGPGA
:.. . .: :... : .. :.. :. :.: : :: : : : : :. :
XP_016 LLRAI---DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FAGLGGLTHLSL--ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQ
. :: .: ::. .: :.:. : ....:::. :::. :: :. .: :... :.
XP_016 LEGLQSLESLSFYDNQLARVPRRA---LEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLK
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 ELDLSGTN-LVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVD
:: :.. . :: . . :..:: : .... .. :
XP_016 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS
290 300 310 320 330 340
350
pF1KE1 TRESAARGPTIL
XP_016 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV
350 360 370 380 390 400
>>NP_963924 (OMIM: 605492) leucine-rich repeat neuronal (713 aa)
initn: 342 init1: 175 opt: 337 Z-score: 299.4 bits: 64.9 E(85289): 6.1e-10
Smith-Waterman score: 377; 33.2% identity (59.3% similar) in 307 aa overlap (19-315:28-322)
10 20 30 40
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVET-FGLFDSFS-LTRVDCSGLGP
:: : : :... . .:. : :::. :
NP_963 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 HIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLR
.: .: : : :.:: . :..: : :: ..:. ::::.: ... : :
NP_963 TAVPPALPAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALP
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHN
: :: : .: :: : .::.. . :... :.:::: ... ::. :. :: :. :
NP_963 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLH--LNSN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 LIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV--PNLRDLP-LRYLSLDGNPLAVIGPGA
:.. . .: :... : .. :.. :. :.: : :: : : : : :. :
NP_963 LLRAI---DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FAGLGGLTHLSL--ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQ
. :: .: ::. .: :.:. : ....:::. :::. :: :. .: :... :.
NP_963 LEGLQSLESLSFYDNQLARVPRRA---LEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLK
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 ELDLSGTN-LVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVD
:: :.. . :: . . :..:: : .... .. :
NP_963 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS
290 300 310 320 330 340
350
pF1KE1 TRESAARGPTIL
NP_963 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV
350 360 370 380 390 400
>>XP_011507368 (OMIM: 605492) PREDICTED: leucine-rich re (713 aa)
initn: 342 init1: 175 opt: 337 Z-score: 299.4 bits: 64.9 E(85289): 6.1e-10
Smith-Waterman score: 377; 33.2% identity (59.3% similar) in 307 aa overlap (19-315:28-322)
10 20 30 40
pF1KE1 MPWPLLLLLAVSGAQTTRPCFPGCQCEVET-FGLFDSFS-LTRVDCSGLGP
:: : : :... . .:. : :::. :
XP_011 MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 HIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGY-TTLAGLDLSHNLLTSISPTAFSRLR
.: .: : : :.:: . :..: : :: ..:. ::::.: ... : :
XP_011 TAVPPALPAGTQTLLLQSNSIVRVDQSEL---GYLANLTELDLSQNSFSDARDCDFHALP
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 YLESLDLSHNGLTALPAESFTS-SPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHN
: :: : .: :: : .::.. . :... :.:::: ... ::. :. :: :. :
XP_011 QLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLH--LNSN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 LIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAV--PNLRDLP-LRYLSLDGNPLAVIGPGA
:.. . .: :... : .. :.. :. :.: : :: : : : : :. :
XP_011 LLRAI---DSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 FAGLGGLTHLSL--ASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQ
. :: .: ::. .: :.:. : ....:::. :::. :: :. .: :... :.
XP_011 LEGLQSLESLSFYDNQLARVPRRA---LEQVPGLKFLDLNKNP-LQRVGPGDFANMLHLK
240 250 260 270 280
290 300 310 320 330 340
pF1KE1 ELDLSGTN-LVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVD
:: :.. . :: . . :..:: : .... .. :
XP_011 ELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALS
290 300 310 320 330 340
350
pF1KE1 TRESAARGPTIL
XP_011 ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTLCAEPPDLQRLPV
350 360 370 380 390 400
353 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:04:26 2016 done: Sun Nov 6 15:04:28 2016
Total Scan time: 7.660 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]