Result of FASTA (omim) for
pFN21AE1025
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1025, 838 aa
1>>>pF1KE1025 838 - 838 aa - 838 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1632+/-0.000447; mu= 12.5835+/- 0.028
mean_var=138.9654+/-28.496, 0's: 0 Z-trim(114.3): 112 B-trim: 126 in 1/53
Lambda= 0.108798
statistics sampled from 23959 (24071) to 23959 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.282), width: 16
Scan time: 12.430
The best scores are: opt bits E(85289)
XP_016868791 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 5622 895.0 0
NP_056250 (OMIM: 607119) E3 ubiquitin-protein liga ( 838) 5622 895.0 0
NP_904355 (OMIM: 607119) E3 ubiquitin-protein liga ( 838) 5622 895.0 0
NP_001267468 (OMIM: 607119) E3 ubiquitin-protein l ( 838) 5622 895.0 0
XP_016868792 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 5622 895.0 0
XP_005250910 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 838) 5622 895.0 0
XP_016868794 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 528) 3465 556.3 1.3e-157
XP_011515258 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784) 3088 497.2 1.2e-139
XP_016868793 (OMIM: 607119) PREDICTED: E3 ubiquiti ( 784) 3088 497.2 1.2e-139
XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 688) 2323 377.1 1.5e-103
XP_006710419 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 732) 2306 374.4 1e-102
NP_699172 (OMIM: 610872) E3 ubiquitin-protein liga ( 732) 2306 374.4 1e-102
NP_001287755 (OMIM: 610872) E3 ubiquitin-protein l ( 731) 2299 373.3 2.1e-102
XP_006710421 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 588) 2297 373.0 2.2e-102
NP_001120833 (OMIM: 610872) E3 ubiquitin-protein l ( 587) 2290 371.9 4.8e-102
XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 317 62.5 2e-08
XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909) 317 62.6 2e-08
XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095) 317 62.6 2.2e-08
XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339) 317 62.6 2.4e-08
XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456) 317 62.6 2.5e-08
NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens] (2517) 317 62.6 2.5e-08
XP_011512726 (OMIM: 607489) PREDICTED: cullin-9 is (2539) 317 62.6 2.5e-08
XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 317 62.6 2.5e-08
XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 317 62.6 2.5e-08
XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 317 62.6 2.5e-08
XP_011519741 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 465) 263 53.6 2.4e-06
NP_005735 (OMIM: 605624) E3 ubiquitin-protein liga ( 557) 263 53.7 2.7e-06
XP_011519740 (OMIM: 605624) PREDICTED: E3 ubiquiti ( 498) 262 53.5 2.8e-06
NP_054643 (OMIM: 167000,211980,600116,602544,60757 ( 316) 249 51.3 8.1e-06
XP_016866398 (OMIM: 167000,211980,600116,602544,60 ( 385) 249 51.4 9.4e-06
NP_054642 (OMIM: 167000,211980,600116,602544,60757 ( 437) 249 51.4 1e-05
XP_011534165 (OMIM: 167000,211980,600116,602544,60 ( 464) 249 51.4 1.1e-05
NP_004553 (OMIM: 167000,211980,600116,602544,60757 ( 465) 249 51.4 1.1e-05
XP_016866397 (OMIM: 167000,211980,600116,602544,60 ( 503) 249 51.5 1.2e-05
XP_011531575 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 432) 240 50.0 2.7e-05
XP_016861023 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 240 50.0 2.8e-05
XP_011531573 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 240 50.0 2.8e-05
XP_016861022 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 240 50.0 2.8e-05
XP_016861024 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 240 50.0 2.8e-05
XP_011531572 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 444) 240 50.0 2.8e-05
XP_011531569 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 240 50.1 3.2e-05
XP_011531567 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 240 50.1 3.2e-05
XP_011531568 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 240 50.1 3.2e-05
XP_011531570 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 516) 240 50.1 3.2e-05
NP_006453 (OMIM: 610924,615895) ranBP-type and C3H ( 468) 226 47.8 0.00013
NP_112506 (OMIM: 610924,615895) ranBP-type and C3H ( 510) 226 47.9 0.00014
XP_005260702 (OMIM: 610924,615895) PREDICTED: ranB ( 527) 226 47.9 0.00015
XP_011527440 (OMIM: 610924,615895) PREDICTED: ranB ( 551) 226 47.9 0.00015
XP_011527439 (OMIM: 610924,615895) PREDICTED: ranB ( 568) 226 47.9 0.00016
NP_001297261 (OMIM: 612487) E3 ubiquitin-protein l ( 921) 214 46.2 0.00084
>>XP_016868791 (OMIM: 607119) PREDICTED: E3 ubiquitin-pr (838 aa)
initn: 5622 init1: 5622 opt: 5622 Z-score: 4777.4 bits: 895.0 E(85289): 0
Smith-Waterman score: 5622; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
790 800 810 820 830
>>NP_056250 (OMIM: 607119) E3 ubiquitin-protein ligase R (838 aa)
initn: 5622 init1: 5622 opt: 5622 Z-score: 4777.4 bits: 895.0 E(85289): 0
Smith-Waterman score: 5622; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
790 800 810 820 830
>>NP_904355 (OMIM: 607119) E3 ubiquitin-protein ligase R (838 aa)
initn: 5622 init1: 5622 opt: 5622 Z-score: 4777.4 bits: 895.0 E(85289): 0
Smith-Waterman score: 5622; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_904 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
790 800 810 820 830
>>NP_001267468 (OMIM: 607119) E3 ubiquitin-protein ligas (838 aa)
initn: 5622 init1: 5622 opt: 5622 Z-score: 4777.4 bits: 895.0 E(85289): 0
Smith-Waterman score: 5622; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
790 800 810 820 830
>>XP_016868792 (OMIM: 607119) PREDICTED: E3 ubiquitin-pr (838 aa)
initn: 5622 init1: 5622 opt: 5622 Z-score: 4777.4 bits: 895.0 E(85289): 0
Smith-Waterman score: 5622; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
790 800 810 820 830
>>XP_005250910 (OMIM: 607119) PREDICTED: E3 ubiquitin-pr (838 aa)
initn: 5622 init1: 5622 opt: 5622 Z-score: 4777.4 bits: 895.0 E(85289): 0
Smith-Waterman score: 5622; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
790 800 810 820 830
>>XP_016868794 (OMIM: 607119) PREDICTED: E3 ubiquitin-pr (528 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2950.4 bits: 556.3 E(85289): 1.3e-157
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 528 aa overlap (311-838:1-528)
290 300 310 320 330 340
pF1KE1 RSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLH
::::::::::::::::::::::::::::::
XP_016 MNDGSCNHMTCAVCGCEFCWLCMKEISDLH
10 20 30
350 360 370 380 390 400
pF1KE1 YLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHN
40 50 60 70 80 90
410 420 430 440 450 460
pF1KE1 RYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGC
100 110 120 130 140 150
470 480 490 500 510 520
pF1KE1 GVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGS
160 170 180 190 200 210
530 540 550 560 570 580
pF1KE1 HMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESG
220 230 240 250 260 270
590 600 610 620 630 640
pF1KE1 TVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGS
280 290 300 310 320 330
650 660 670 680 690 700
pF1KE1 ATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQ
340 350 360 370 380 390
710 720 730 740 750 760
pF1KE1 QSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSTNSSEFEAPSLSDSMPSVADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNIL
400 410 420 430 440 450
770 780 790 800 810 820
pF1KE1 PEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETN
460 470 480 490 500 510
830
pF1KE1 NNHSHQTMELKVAIQTEI
::::::::::::::::::
XP_016 NNHSHQTMELKVAIQTEI
520
>>XP_011515258 (OMIM: 607119) PREDICTED: E3 ubiquitin-pr (784 aa)
initn: 3030 init1: 3030 opt: 3088 Z-score: 2628.2 bits: 497.2 E(85289): 1.2e-139
Smith-Waterman score: 5140; 93.6% identity (93.6% similar) in 838 aa overlap (1-838:1-784)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
:::::::::::::::
XP_011 TLSVIVSPVVAAVTV---------------------------------------------
430
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ---------DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
440 450 460 470 480
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
550 560 570 580 590 600
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
610 620 630 640 650 660
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
670 680 690 700 710 720
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
730 740 750 760 770 780
>>XP_016868793 (OMIM: 607119) PREDICTED: E3 ubiquitin-pr (784 aa)
initn: 3030 init1: 3030 opt: 3088 Z-score: 2628.2 bits: 497.2 E(85289): 1.2e-139
Smith-Waterman score: 5140; 93.6% identity (93.6% similar) in 838 aa overlap (1-838:1-784)
10 20 30 40 50 60
pF1KE1 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRRISIGSLFRRKKDNKRKSRELNGGVDGIASIESIHSEMCTDKNSIFSTNTSSDNGLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIHNRYEGKDVSKHKRNLAIAGGV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 TLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGGCGVSAGNGKGVRIEFDDENDI
:::::::::::::::
XP_016 TLSVIVSPVVAAVTV---------------------------------------------
430
490 500 510 520 530 540
pF1KE1 NVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------DTTSVAEARHNPSIGEGSVGGLTGSLSASGSHMDRIGAIRDNLSETASTMA
440 450 460 470 480
550 560 570 580 590 600
pF1KE1 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGESGTVSLGTVSDNASTKAMAGSI
490 500 510 520 530 540
610 620 630 640 650 660
pF1KE1 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDDGSATRSHAGGSSSGLPEGKSSA
550 560 570 580 590 600
670 680 690 700 710 720
pF1KE1 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKWSKEATAGKKSKSGKLRKKGNMKINETREDMDAQLLEQQSTNSSEFEAPSLSDSMPSV
610 620 630 640 650 660
730 740 750 760 770 780
pF1KE1 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSHSSHFSEFSCSDLESMKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVV
670 680 690 700 710 720
790 800 810 820 830
pF1KE1 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTEI
730 740 750 760 770 780
>>XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquitin-pr (688 aa)
initn: 2394 init1: 1204 opt: 2323 Z-score: 1980.1 bits: 377.1 E(85289): 1.5e-103
Smith-Waterman score: 2329; 59.7% identity (75.6% similar) in 610 aa overlap (130-729:117-668)
100 110 120 130 140 150
pF1KE1 EMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCL
.::::::.: .: : ...: :::: :::
XP_006 EAEAEAAAAAAEPGFDDEEAAEGGGPGAEEVECPLCLVRLPPERAPRLLSCPHRSCRDCL
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE1 RQYLRIEISESRVNISCPECTERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWC
:.:::.::::::: ::::::.::.:::::::.:.: ::.:::::::::.:..:::::::
XP_006 RHYLRLEISESRVPISCPECSERLNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRWC
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE1 PAPDCGYAVIAFGCASCPKLTCGREGCGTEFCYHCKQIWHPNQTCDAARQERAQSLRLRT
:::::::::::.:::::::::: :::: :::::::::::::::::: :::.:::.::.::
XP_006 PAPDCGYAVIAYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRT
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE1 IRSSSISYSQESGAAADDIKPCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL
..:..::.:::: : :::::::::.::::::::::::::::::::::::::::::::::
XP_006 KHTSGLSYGQESGPA-DDIKPCPRCSAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE1 HYLSPSGCTFWGKKPWSRKKKILWQLGTLVGAPVGIALIAGIAIPAMIIGIPVYVGRKIH
:::::::::::::::::::::::::::::.::::::.::::::::::.::::::::::::
XP_006 HYLSPSGCTFWGKKPWSRKKKILWQLGTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIH
330 340 350 360 370 380
400 410 420 430 440 450
pF1KE1 NRYEGKDVSKHKRNLAIAGGVTLSVIVSPVVAAVTVGIGVPIMLAYVYGVVPISLCRSGG
.::::. .:::::::::.::::::::.:::.:::.::::::::::::::::::::::.::
XP_006 SRYEGRKTSKHKRNLAITGGVTLSVIASPVIAAVSVGIGVPIMLAYVYGVVPISLCRGGG
390 400 410 420 430 440
460 470 480 490 500 510
pF1KE1 CGVSAGNGKGVRIEFDDENDINVGGTNTAVDTTSVAEARHNPSIGEGSVGGLTGSLSASG
::::..:::::.:::: :.: : :..: . .: .::::::.:. :::. ::.::
XP_006 CGVSTANGKGVKIEFD-EDD----GPITVAD---AWRALKNPSIGESSIEGLTSVLSTSG
450 460 470 480 490
520 530 540 550 560 570
pF1KE1 SHMDRIGAIRDNLSETASTMALAGASITGSLSGSAMVNCFNRLEVQADVQKERYSLSGES
: : ..... ::::: ::.:....:.. .:. : .::
XP_006 SPTDGLSVMQGPYSETASFAALSGGTLSGGILSSG---------------KGKYS-----
500 510 520 530
580 590 600 610 620 630
pF1KE1 GTVSLGTVSDNASTKAMAGSILNSYIPLDKEGNSMEVQVDIESKPSKFRHNSGSSSVDD-
.: :.::.:::::.:::... ::::. :.
XP_006 -----------------------------RECNNMEIQVDIEAKPSHYQLVSGSSTEDSL
540 550 560
640 650 660 670 680 690
pF1KE1 ---GSATRSHAGGSSSGLPEGKSSATKWSKEATAGKKSKSGKLRKKGNMKINETREDMDA
.. .... ::..: : . : : :: . .: :. ::
XP_006 HVHAQMAENEEEGSGGGGSEEDPPCRHQSCEQKDCLASKPWDISLAQPESIRSDLESSDA
570 580 590 600 610 620
700 710 720 730 740
pF1KE1 QLLEQQSTNSSEFEAP-SLSDSMPSV-----ADSHSSHFSEFSCSDLESMKTSCSHGSSD
: . . .:.: .: : . . ::. : : :.:..
XP_006 QSDDVPDITSDECGSPRSHTAACPSTPRAQGAPSPSAHMNLSALAEGQTVLKPEGGEARV
630 640 650 660 670 680
750 760 770 780 790 800
pF1KE1 YHTRFATVNILPEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVD
838 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:37:13 2016 done: Mon Nov 7 16:37:15 2016
Total Scan time: 12.430 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]