FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1009, 220 aa
  1>>>pF1KE1009 220 - 220 aa - 220 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.3134+/-0.000293; mu= -2.1658+/- 0.018
 mean_var=232.9800+/-47.791, 0's: 0 Z-trim(125.8): 3  B-trim: 823 in 1/57
 Lambda= 0.084026
 statistics sampled from 50415 (50418) to 50415 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.858), E-opt: 0.2 (0.591), width:  16
 Scan time:  6.750

The best scores are:                                      opt bits E(85289)
NP_150601 (OMIM: 606185) tumor protein p53-inducib ( 240)  337 52.2 8.7e-07
XP_011515688 (OMIM: 606185) PREDICTED: tumor prote ( 240)  337 52.2 8.7e-07


>>NP_150601 (OMIM: 606185) tumor protein p53-inducible n  (240 aa)
 initn: 393 init1: 167 opt: 337  Z-score: 242.9  bits: 52.2 E(85289): 8.7e-07
Smith-Waterman score: 355; 30.8% identity (56.1% similar) in 253 aa overlap (1-220:1-240)

               10        20        30        40           50       
pF1KE1 MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDS---YAAPPSPGAAPAPA
       :::::...: .  :   . . :. :  .::  : :...:. :.   ..:           
NP_150 MFQRLNKMFVGEVSSSSNQE-PE-FNEKED--DEWILVDFIDTCTGFSAEEEEEEEDISE
               10        20            30        40        50      

        60                                  70        80        90 
pF1KE1 GRPPPAPSL--------------------------MDESWFVTPPACFTAEGPGLGPARL
         :   ::.                          :.::::.::: :::: : ::   ..
NP_150 ESPTEHPSVFSCLPASLECLADTSDSCFLQFESCPMEESWFITPPPCFTA-G-GLTTIKV
         60        70        80        90       100         110    

             100       110       120       130       140       150 
pF1KE1 QSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAAR
       ..::.:.:::::::::::.. ..    ::    : .:.    .:       .. . . ..
NP_150 ETSPMENLLIEHPSMSVYAVHNSC---PG----LSEATRGTDELHSPSSPRVEAQNEMGQ
          120       130          140           150       160       

                 160       170       180       190       200       
pF1KE1 H----AAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQS
       :    .: : :....::.  . :  :  ....::. :. ....::: .:. .::. :...
NP_150 HIHCYVAALAAHTTFLEQPKSFRPSQWIKEHSERQPLNRNSLRRQNLTRDCHPRQVKHNG
       170       180       190       200       210       220       

       210       220
pF1KE1 SFIYQPCQRQFNY
         ..::: ::.::
NP_150 WVVHQPCPRQYNY
       230       240

>>XP_011515688 (OMIM: 606185) PREDICTED: tumor protein p  (240 aa)
 initn: 393 init1: 167 opt: 337  Z-score: 242.9  bits: 52.2 E(85289): 8.7e-07
Smith-Waterman score: 355; 30.8% identity (56.1% similar) in 253 aa overlap (1-220:1-240)

               10        20        30        40           50       
pF1KE1 MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDS---YAAPPSPGAAPAPA
       :::::...: .  :   . . :. :  .::  : :...:. :.   ..:           
XP_011 MFQRLNKMFVGEVSSSSNQE-PE-FNEKED--DEWILVDFIDTCTGFSAEEEEEEEDISE
               10        20            30        40        50      

        60                                  70        80        90 
pF1KE1 GRPPPAPSL--------------------------MDESWFVTPPACFTAEGPGLGPARL
         :   ::.                          :.::::.::: :::: : ::   ..
XP_011 ESPTEHPSVFSCLPASLECLADTSDSCFLQFESCPMEESWFITPPPCFTA-G-GLTTIKV
         60        70        80        90       100         110    

             100       110       120       130       140       150 
pF1KE1 QSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAAR
       ..::.:.:::::::::::.. ..    ::    : .:.    .:       .. . . ..
XP_011 ETSPMENLLIEHPSMSVYAVHNSC---PG----LSEATRGTDELHSPSSPRVEAQNEMGQ
          120       130          140           150       160       

                 160       170       180       190       200       
pF1KE1 H----AAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQS
       :    .: : :....::.  . :  :  ....::. :. ....::: .:. .::. :...
XP_011 HIHCYVAALAAHTTFLEQPKSFRPSQWIKEHSERQPLNRNSLRRQNLTRDCHPRQVKHNG
       170       180       190       200       210       220       

       210       220
pF1KE1 SFIYQPCQRQFNY
         ..::: ::.::
XP_011 WVVHQPCPRQYNY
       230       240




220 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 20:12:21 2016 done: Sun Nov  6 20:12:22 2016
 Total Scan time:  6.750 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]