Result of FASTA (omim) for
pFN21AE0995
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0995, 648 aa
1>>>pF1KE0995 648 - 648 aa - 648 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8795+/-0.000578; mu= -0.8420+/- 0.035
mean_var=510.1811+/-111.537, 0's: 0 Z-trim(118.2): 1838 B-trim: 0 in 0/54
Lambda= 0.056782
statistics sampled from 28451 (30852) to 28451 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.362), width: 16
Scan time: 11.700
The best scores are: opt bits E(85289)
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648) 4362 373.1 1.7e-102
NP_208382 (OMIM: 613167) serine/threonine-protein ( 648) 4362 373.1 1.7e-102
XP_011532470 (OMIM: 613167) PREDICTED: serine/thre ( 592) 3535 305.3 4e-82
XP_011532471 (OMIM: 613167) PREDICTED: serine/thre ( 508) 3252 282.1 3.5e-75
NP_001182344 (OMIM: 604742) serine/threonine-prote ( 422) 1063 102.6 3e-21
NP_001182345 (OMIM: 604742) serine/threonine-prote ( 433) 1063 102.6 3e-21
XP_016876336 (OMIM: 604742) PREDICTED: serine/thre ( 708) 1063 102.9 4e-21
NP_004725 (OMIM: 604742) serine/threonine-protein ( 729) 1063 103.0 4.1e-21
NP_001317001 (OMIM: 604742) serine/threonine-prote ( 740) 1063 103.0 4.1e-21
NP_001317000 (OMIM: 604742) serine/threonine-prote ( 740) 1063 103.0 4.1e-21
XP_016863321 (OMIM: 613166) PREDICTED: serine/thre ( 717) 1043 101.3 1.3e-20
XP_005262843 (OMIM: 613166) PREDICTED: serine/thre ( 765) 1043 101.4 1.3e-20
NP_001035350 (OMIM: 613166) serine/threonine-prote ( 766) 1043 101.4 1.3e-20
XP_005262842 (OMIM: 613166) PREDICTED: serine/thre ( 782) 1043 101.4 1.3e-20
NP_001035351 (OMIM: 613166) serine/threonine-prote ( 783) 1043 101.4 1.3e-20
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473) 799 81.1 1e-14
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473) 799 81.1 1e-14
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473) 799 81.1 1e-14
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 786 79.8 1.9e-14
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 785 79.7 2e-14
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 785 79.7 2e-14
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 785 79.7 2e-14
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 786 79.9 2e-14
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 785 79.8 2e-14
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360) 759 77.6 8.6e-14
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476) 758 77.7 1.1e-13
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476) 758 77.7 1.1e-13
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366) 754 77.2 1.2e-13
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372) 754 77.2 1.2e-13
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 753 77.1 1.2e-13
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361) 753 77.1 1.2e-13
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 753 77.2 1.3e-13
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426) 753 77.2 1.3e-13
XP_006714393 (OMIM: 607708) PREDICTED: calcium/cal ( 478) 727 75.2 6.2e-13
NP_001308506 (OMIM: 607708) calcium/calmodulin-dep ( 491) 727 75.2 6.3e-13
XP_016864166 (OMIM: 607708) PREDICTED: calcium/cal ( 491) 727 75.2 6.3e-13
NP_001308504 (OMIM: 607708) calcium/calmodulin-dep ( 492) 727 75.2 6.3e-13
NP_001308512 (OMIM: 607708) calcium/calmodulin-dep ( 492) 727 75.2 6.3e-13
NP_001308497 (OMIM: 607708) calcium/calmodulin-dep ( 503) 727 75.2 6.4e-13
XP_011530597 (OMIM: 607708) PREDICTED: calcium/cal ( 510) 727 75.2 6.4e-13
XP_016864163 (OMIM: 607708) PREDICTED: calcium/cal ( 511) 727 75.2 6.4e-13
XP_016864162 (OMIM: 607708) PREDICTED: calcium/cal ( 512) 727 75.2 6.5e-13
NP_001308501 (OMIM: 607708) calcium/calmodulin-dep ( 512) 727 75.2 6.5e-13
>>XP_011532469 (OMIM: 613167) PREDICTED: serine/threonin (648 aa)
initn: 4362 init1: 4362 opt: 4362 Z-score: 1961.2 bits: 373.1 E(85289): 1.7e-102
Smith-Waterman score: 4362; 100.0% identity (100.0% similar) in 648 aa overlap (1-648:1-648)
10 20 30 40 50 60
pF1KE0 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
550 560 570 580 590 600
610 620 630 640
pF1KE0 RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
610 620 630 640
>>NP_208382 (OMIM: 613167) serine/threonine-protein kina (648 aa)
initn: 4362 init1: 4362 opt: 4362 Z-score: 1961.2 bits: 373.1 E(85289): 1.7e-102
Smith-Waterman score: 4362; 100.0% identity (100.0% similar) in 648 aa overlap (1-648:1-648)
10 20 30 40 50 60
pF1KE0 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
550 560 570 580 590 600
610 620 630 640
pF1KE0 RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_208 RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
610 620 630 640
>>XP_011532470 (OMIM: 613167) PREDICTED: serine/threonin (592 aa)
initn: 3938 init1: 3535 opt: 3535 Z-score: 1595.4 bits: 305.3 E(85289): 4e-82
Smith-Waterman score: 3830; 91.4% identity (91.4% similar) in 648 aa overlap (1-648:1-592)
10 20 30 40 50 60
pF1KE0 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEK------------
490 500 510 520
550 560 570 580 590 600
pF1KE0 VILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKK
::::::::::::::::
XP_011 --------------------------------------------AAKDLVSRLLVVDPKK
530 540
610 620 630 640
pF1KE0 RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
550 560 570 580 590
>>XP_011532471 (OMIM: 613167) PREDICTED: serine/threonin (508 aa)
initn: 3251 init1: 3251 opt: 3252 Z-score: 1470.8 bits: 282.1 E(85289): 3.5e-75
Smith-Waterman score: 3252; 99.4% identity (99.6% similar) in 488 aa overlap (1-488:1-488)
10 20 30 40 50 60
pF1KE0 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGKEPLTLKSIQVAVEELYPNKARALTLAQHSRAPSPRLRSRLFSKALKGDHRCGETETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSCSEVAGCKAAMRHQGKIPEELSLDDRARTQKKWGRGKWEPEPSSKPPREATLEERHAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEKHLGVEIEKTSGEIIRCEKCKRERELQQSLERERLSLGTSELDMGKGPMYDVEKLVRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSCRRSPEANPASGEEGWKGDSHRSSPRNPTQELRRPSKSMDKKEDRGPEDQESHAQGAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHGGWLLREHQAGFEKLRRTRGEEKEAEKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKPCMSGGRRMTLRDDQPAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 ENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAG
:::: .:
XP_011 ENLLPVENGPWREKVRETMKDQVRRWQR
490 500
>>NP_001182344 (OMIM: 604742) serine/threonine-protein k (422 aa)
initn: 1064 init1: 1031 opt: 1063 Z-score: 502.5 bits: 102.6 E(85289): 3e-21
Smith-Waterman score: 1063; 52.7% identity (79.6% similar) in 294 aa overlap (348-641:75-367)
320 330 340 350 360 370
pF1KE0 PAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRE
: :.. ..:..::.:::::::::::: .:
NP_001 SSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERS
50 60 70 80 90 100
380 390 400 410 420 430
pF1KE0 TRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG
: . ::.::: ::. .::: :...:. :.. ..::::: : : ... :.::..: :.::
NP_001 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG
110 120 130 140 150 160
440 450 460 470 480 490
pF1KE0 DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKL
:::::: . :. : ::. :...: .:. ..:. .:::::.::::::: ...: : .:::
NP_001 DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
170 180 190 200 210 220
500 510 520 530 540 550
pF1KE0 ADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE
.::::: : :..:::::::::::::..: ::::.::.:::::: :::::::::::.
NP_001 GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG
230 240 250 260 270 280
560 570 580 590 600 610
pF1KE0 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG
::. ::. : .:. .: :::::.::.::.:.. .:.:: .:..: :::.:::.. :
NP_001 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG
290 300 310 320 330 340
620 630 640
pF1KE0 KTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
.. ..: .:. . . :: . :
NP_001 LPEN-EHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWI
350 360 370 380 390 400
>>NP_001182345 (OMIM: 604742) serine/threonine-protein k (433 aa)
initn: 1064 init1: 1031 opt: 1063 Z-score: 502.4 bits: 102.6 E(85289): 3e-21
Smith-Waterman score: 1063; 52.7% identity (79.6% similar) in 294 aa overlap (348-641:75-367)
320 330 340 350 360 370
pF1KE0 PAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRE
: :.. ..:..::.:::::::::::: .:
NP_001 SSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERS
50 60 70 80 90 100
380 390 400 410 420 430
pF1KE0 TRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG
: . ::.::: ::. .::: :...:. :.. ..::::: : : ... :.::..: :.::
NP_001 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG
110 120 130 140 150 160
440 450 460 470 480 490
pF1KE0 DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKL
:::::: . :. : ::. :...: .:. ..:. .:::::.::::::: ...: : .:::
NP_001 DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
170 180 190 200 210 220
500 510 520 530 540 550
pF1KE0 ADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE
.::::: : :..:::::::::::::..: ::::.::.:::::: :::::::::::.
NP_001 GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG
230 240 250 260 270 280
560 570 580 590 600 610
pF1KE0 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG
::. ::. : .:. .: :::::.::.::.:.. .:.:: .:..: :::.:::.. :
NP_001 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG
290 300 310 320 330 340
620 630 640
pF1KE0 KTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
.. ..: .:. . . :: . :
NP_001 LPEN-EHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYK
350 360 370 380 390 400
>>XP_016876336 (OMIM: 604742) PREDICTED: serine/threonin (708 aa)
initn: 1064 init1: 1031 opt: 1063 Z-score: 500.2 bits: 102.9 E(85289): 4e-21
Smith-Waterman score: 1063; 52.7% identity (79.6% similar) in 294 aa overlap (348-641:382-674)
320 330 340 350 360 370
pF1KE0 PAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRE
: :.. ..:..::.:::::::::::: .:
XP_016 SSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERS
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE0 TRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG
: . ::.::: ::. .::: :...:. :.. ..::::: : : ... :.::..: :.::
XP_016 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE0 DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKL
:::::: . :. : ::. :...: .:. ..:. .:::::.::::::: ...: : .:::
XP_016 DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE0 ADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE
.::::: : :..:::::::::::::..: ::::.::.:::::: :::::::::::.
XP_016 GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE0 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG
::. ::. : .:. .: :::::.::.::.:.. .:.:: .:..: :::.:::.. :
XP_016 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG
600 610 620 630 640 650
620 630 640
pF1KE0 KTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
.. ..: .:. . . :: . :
XP_016 LPEN-EHQLSVAGKIKKHFNTGPKPNSTAAGVSVIAAPARPPLLIRRGRFSDEDATRM
660 670 680 690 700
>>NP_004725 (OMIM: 604742) serine/threonine-protein kina (729 aa)
initn: 1064 init1: 1031 opt: 1063 Z-score: 500.1 bits: 103.0 E(85289): 4.1e-21
Smith-Waterman score: 1063; 52.7% identity (79.6% similar) in 294 aa overlap (348-641:382-674)
320 330 340 350 360 370
pF1KE0 PAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRE
: :.. ..:..::.:::::::::::: .:
NP_004 SSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERS
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE0 TRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG
: . ::.::: ::. .::: :...:. :.. ..::::: : : ... :.::..: :.::
NP_004 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE0 DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKL
:::::: . :. : ::. :...: .:. ..:. .:::::.::::::: ...: : .:::
NP_004 DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE0 ADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE
.::::: : :..:::::::::::::..: ::::.::.:::::: :::::::::::.
NP_004 GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE0 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG
::. ::. : .:. .: :::::.::.::.:.. .:.:: .:..: :::.:::.. :
NP_004 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG
600 610 620 630 640 650
620 630 640
pF1KE0 KTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
.. ..: .:. . . :: . :
NP_004 LPEN-EHQLSVAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWI
660 670 680 690 700 710
>>NP_001317001 (OMIM: 604742) serine/threonine-protein k (740 aa)
initn: 1064 init1: 1031 opt: 1063 Z-score: 500.0 bits: 103.0 E(85289): 4.1e-21
Smith-Waterman score: 1063; 52.7% identity (79.6% similar) in 294 aa overlap (348-641:382-674)
320 330 340 350 360 370
pF1KE0 PAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRE
: :.. ..:..::.:::::::::::: .:
NP_001 SSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERS
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE0 TRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG
: . ::.::: ::. .::: :...:. :.. ..::::: : : ... :.::..: :.::
NP_001 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE0 DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKL
:::::: . :. : ::. :...: .:. ..:. .:::::.::::::: ...: : .:::
NP_001 DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE0 ADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE
.::::: : :..:::::::::::::..: ::::.::.:::::: :::::::::::.
NP_001 GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE0 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG
::. ::. : .:. .: :::::.::.::.:.. .:.:: .:..: :::.:::.. :
NP_001 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG
600 610 620 630 640 650
620 630 640
pF1KE0 KTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
.. ..: .:. . . :: . :
NP_001 LPEN-EHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYK
660 670 680 690 700 710
>>NP_001317000 (OMIM: 604742) serine/threonine-protein k (740 aa)
initn: 1064 init1: 1031 opt: 1063 Z-score: 500.0 bits: 103.0 E(85289): 4.1e-21
Smith-Waterman score: 1063; 52.7% identity (79.6% similar) in 294 aa overlap (348-641:382-674)
320 330 340 350 360 370
pF1KE0 PAKLEKEPKTRPEENKPERPSGRKPRPMGIIAANVEKHYETGRVIGDGNFAVVKECRHRE
: :.. ..:..::.:::::::::::: .:
NP_001 SSTSLASTKVCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERS
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE0 TRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHEVYETDMEIYLILEYVQGG
: . ::.::: ::. .::: :...:. :.. ..::::: : : ... :.::..: :.::
NP_001 TAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGG
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE0 DLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKL
:::::: . :. : ::. :...: .:. ..:. .:::::.::::::: ...: : .:::
NP_001 DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKL
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE0 ADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPE
.::::: : :..:::::::::::::..: ::::.::.:::::: :::::::::::.
NP_001 GDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE0 RDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIETAG
::. ::. : .:. .: :::::.::.::.:.. .:.:: .:..: :::.:::.. :
NP_001 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG
600 610 620 630 640 650
620 630 640
pF1KE0 KTNTVKRQKQVSPSSEGHFRSQHKRVVEQVS
.. ..: .:. . . :: . :
NP_001 LPEN-EHQLSVAGKIKKHFNTGPKPNSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYK
660 670 680 690 700 710
648 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:39:08 2016 done: Mon Nov 7 18:39:10 2016
Total Scan time: 11.700 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]