Result of FASTA (omim) for
pFN21AE0994
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0994, 647 aa
1>>>pF1KE0994 647 - 647 aa - 647 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9974+/-0.000401; mu= 11.9496+/- 0.025
mean_var=116.1752+/-23.059, 0's: 0 Z-trim(114.2): 11 B-trim: 0 in 0/54
Lambda= 0.118992
statistics sampled from 23873 (23882) to 23873 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.28), width: 16
Scan time: 9.700
The best scores are: opt bits E(85289)
XP_005273258 (OMIM: 606980,612016) PREDICTED: atyp ( 647) 4310 751.4 2.3e-216
XP_016857341 (OMIM: 606980,612016) PREDICTED: atyp ( 647) 4310 751.4 2.3e-216
NP_064632 (OMIM: 606980,612016) atypical kinase AD ( 647) 4310 751.4 2.3e-216
XP_011542543 (OMIM: 606980,612016) PREDICTED: atyp ( 647) 4310 751.4 2.3e-216
XP_011542541 (OMIM: 606980,612016) PREDICTED: atyp ( 647) 4310 751.4 2.3e-216
XP_011542542 (OMIM: 606980,612016) PREDICTED: atyp ( 647) 4310 751.4 2.3e-216
XP_011542540 (OMIM: 606980,612016) PREDICTED: atyp ( 647) 4310 751.4 2.3e-216
NP_079152 (OMIM: 615567,615573) aarF domain-contai ( 544) 1986 352.4 2.5e-96
NP_001136027 (OMIM: 615567,615573) aarF domain-con ( 503) 1518 272.1 3.5e-72
>>XP_005273258 (OMIM: 606980,612016) PREDICTED: atypical (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>XP_016857341 (OMIM: 606980,612016) PREDICTED: atypical (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>NP_064632 (OMIM: 606980,612016) atypical kinase ADCK3, (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>XP_011542543 (OMIM: 606980,612016) PREDICTED: atypical (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>XP_011542541 (OMIM: 606980,612016) PREDICTED: atypical (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>XP_011542542 (OMIM: 606980,612016) PREDICTED: atypical (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>XP_011542540 (OMIM: 606980,612016) PREDICTED: atypical (647 aa)
initn: 4310 init1: 4310 opt: 4310 Z-score: 4005.5 bits: 751.4 E(85289): 2.3e-216
Smith-Waterman score: 4310; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KE0 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLV
550 560 570 580 590 600
610 620 630 640
pF1KE0 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ
610 620 630 640
>>NP_079152 (OMIM: 615567,615573) aarF domain-containing (544 aa)
initn: 1948 init1: 1709 opt: 1986 Z-score: 1850.5 bits: 352.4 E(85289): 2.5e-96
Smith-Waterman score: 1986; 58.0% identity (81.4% similar) in 522 aa overlap (129-644:11-524)
100 110 120 130 140 150
pF1KE0 PDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGF
: :: .. .: : : .:. :
NP_079 MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGS
10 20 30 40
160 170 180 190 200 210
pF1KE0 QRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFG
. :.:: .: :: :::..::.:. : : . ::...::::::..::.::::::
NP_079 WAQKFYQD-GPGRGLGEEDIRRAREARPR---KTPRPQLSDRSRERKVPASRISRLANFG
50 60 70 80 90
220 230 240 250 260 270
pF1KE0 GLAVGLGFGALAEVAKKS-----LRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGA
:::::::.:.:::.:::: :.:: :: : ::::::::::::::.::: ::::
NP_079 GLAVGLGLGVLAEMAKKSMPGGRLQSEGGSG----LDSSPFLSEANAERIVQTLCTVRGA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE0 ALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEE
:::.::::::::..::.:.: .::::::::::::: ::...:...:: .:. :. .::
NP_079 ALKVGQMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEE
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE0 RPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEH
::::::::::: . .. : :::.::::::.::::.:::.::.:::.:: :: ::: :.
NP_079 VPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQ
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE0 LIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPL
...:..::: ::::.::::::..::.:: . ::: :: .: :::. .:: ::..: ::
NP_079 SLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPL
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE0 DQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATRE
:: .::::..::.::...:.:::::::::.::::::::.::.:: ..:.:.::::::.::
NP_079 DQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASRE
340 350 360 370 380 390
520 530 540 550 560 570
pF1KE0 YDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASD
. ::: ::....:::: ::. : :: ..:::::.:.:.. :::..:..:::: ::..
NP_079 FGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQ
400 410 420 430 440 450
580 590 600 610 620 630
pF1KE0 EPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMF
:.:::. :...:..::::.::::: :::::::.::::..:.:: :..:.:.. :. .:
NP_079 GPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLF
460 470 480 490 500 510
640
pF1KE0 EEAYSNY-CKRQAQQ
...: : .::
NP_079 QDTYHRYWASRQPDAATAGSLPTKGDSWVDPS
520 530 540
>>NP_001136027 (OMIM: 615567,615573) aarF domain-contain (503 aa)
initn: 1740 init1: 1505 opt: 1518 Z-score: 1416.8 bits: 272.1 E(85289): 3.5e-72
Smith-Waterman score: 1722; 52.2% identity (75.8% similar) in 517 aa overlap (129-644:11-483)
100 110 120 130 140 150
pF1KE0 PDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGF
: :: .. .: : : .:. :
NP_001 MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGS
10 20 30 40
160 170 180 190 200 210
pF1KE0 QRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFG
. :.:: .: :: :::..::.:. : : . ::...::::::..::.::::::
NP_001 WAQKFYQD-GPGRGLGEEDIRRAREARPR---KTPRPQLSDRSRERKVPASRISRLANFG
50 60 70 80 90
220 230 240 250 260 270
pF1KE0 GLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLG
:::::::.:.:::.::::. :.:. : :
NP_001 GLAVGLGLGVLAEMAKKSM----PGGR---LQS---------------------------
100 110 120
280 290 300 310 320 330
pF1KE0 QMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAA
:..::.:.: .::::::::::::: ::...:...:: .:. :. .:: ::::
NP_001 ------DNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAA
130 140 150 160 170
340 350 360 370 380 390
pF1KE0 ASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVL
::::::: . .. : :::.::::::.::::.:::.::.:::.:: :: ::: :. ...:
NP_001 ASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQAL
180 190 200 210 220 230
400 410 420 430 440 450
pF1KE0 RRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEG
..::: ::::.::::::..::.:: . ::: :: .: :::. .:: ::..: :::: .:
NP_001 QQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQG
240 250 260 270 280 290
460 470 480 490 500 510
pF1KE0 LSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSF
:::..::.::...:.:::::::::.::::::::.::.:: ..:.:.::::::.::. :
NP_001 LSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEF
300 310 320 330 340 350
520 530 540 550 560 570
pF1KE0 TDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDF
:: ::....:::: ::. : :: ..:::::.:.:.. :::..:..:::: ::.. :.::
NP_001 TDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDF
360 370 380 390 400 410
580 590 600 610 620 630
pF1KE0 GTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYS
:. :...:..::::.::::: :::::::.::::..:.:: :..:.:.. :. .:...:
NP_001 GSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYH
420 430 440 450 460 470
640
pF1KE0 NY-CKRQAQQ
: .::
NP_001 RYWASRQPDAATAGSLPTKGDSWVDPS
480 490 500
647 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:49:22 2016 done: Sun Nov 6 05:49:23 2016
Total Scan time: 9.700 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]