Result of FASTA (omim) for
pFN21AE0982
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0982, 587 aa
1>>>pF1KE0982 587 - 587 aa - 587 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.6243+/-0.00054; mu= -21.8175+/- 0.033
mean_var=765.0675+/-170.780, 0's: 0 Z-trim(118.3): 687 B-trim: 0 in 0/57
Lambda= 0.046369
statistics sampled from 30263 (31130) to 30263 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.365), width: 16
Scan time: 9.670
The best scores are: opt bits E(85289)
XP_011524377 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 3971 282.0 3.9e-75
XP_011524378 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 3971 282.0 3.9e-75
XP_016881328 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 3971 282.0 3.9e-75
NP_002738 (OMIM: 176949) mitogen-activated protein ( 587) 3971 282.0 3.9e-75
XP_005258356 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 3971 282.0 3.9e-75
XP_011524376 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 3971 282.0 3.9e-75
XP_011524379 (OMIM: 176949) PREDICTED: mitogen-act ( 412) 2793 203.0 1.6e-51
NP_001278968 (OMIM: 176949) mitogen-activated prot ( 376) 2598 189.9 1.3e-47
XP_011524380 (OMIM: 176949) PREDICTED: mitogen-act ( 336) 2120 157.9 5.1e-38
XP_005254596 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 1791 136.3 3.5e-31
XP_011520084 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 1791 136.3 3.5e-31
XP_005254594 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 1791 136.3 3.5e-31
NP_002739 (OMIM: 602904) mitogen-activated protein ( 721) 1791 136.3 3.5e-31
XP_005254595 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 1791 136.3 3.5e-31
NP_001278969 (OMIM: 176949) mitogen-activated prot ( 233) 1512 117.0 7.1e-26
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 899 76.2 2.1e-13
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 899 76.2 2.1e-13
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 894 75.9 2.7e-13
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 847 72.7 2.3e-12
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 755 67.0 2.7e-10
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 755 67.0 2.7e-10
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 755 67.0 2.7e-10
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 748 66.5 3.8e-10
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 748 66.5 3.8e-10
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 748 66.5 3.8e-10
NP_001103361 (OMIM: 601795) mitogen-activated prot ( 335) 692 62.3 2.9e-09
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 683 61.8 4.6e-09
NP_057315 (OMIM: 609476) serine/threonine-protein ( 527) 629 58.4 7.2e-08
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 593 55.7 3e-07
XP_011522259 (OMIM: 602521) PREDICTED: mitogen-act ( 677) 598 56.4 3.5e-07
NP_620601 (OMIM: 602521) mitogen-activated protein ( 677) 598 56.4 3.5e-07
NP_620583 (OMIM: 600289) mitogen-activated protein ( 307) 587 55.3 3.6e-07
NP_112557 (OMIM: 603309) cyclin-dependent kinase 1 (1452) 606 57.4 4e-07
NP_003709 (OMIM: 603309) cyclin-dependent kinase 1 (1512) 589 56.2 8.9e-07
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 563 53.6 1e-06
NP_001310254 (OMIM: 601158) mitogen-activated prot ( 384) 567 54.0 1e-06
NP_620634 (OMIM: 601158) mitogen-activated protein ( 384) 567 54.0 1e-06
NP_001310250 (OMIM: 601158) mitogen-activated prot ( 384) 567 54.0 1e-06
XP_016863929 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 566 54.0 1.1e-06
NP_001310259 (OMIM: 601158) mitogen-activated prot ( 427) 567 54.1 1.1e-06
NP_001265476 (OMIM: 601158) mitogen-activated prot ( 427) 567 54.1 1.1e-06
NP_001310251 (OMIM: 601158) mitogen-activated prot ( 427) 567 54.1 1.1e-06
NP_001310252 (OMIM: 601158) mitogen-activated prot ( 427) 567 54.1 1.1e-06
XP_006714332 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 566 54.0 1.2e-06
XP_016863917 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 566 54.0 1.2e-06
XP_016863916 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 566 54.0 1.2e-06
XP_005258045 (OMIM: 609476) PREDICTED: serine/thre ( 498) 568 54.2 1.2e-06
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 563 53.7 1.2e-06
XP_005257515 (OMIM: 615514) PREDICTED: cyclin-depe (1256) 580 55.5 1.2e-06
XP_016880242 (OMIM: 615514) PREDICTED: cyclin-depe (1261) 580 55.5 1.2e-06
>>XP_011524377 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 3971 init1: 3971 opt: 3971 Z-score: 1470.0 bits: 282.0 E(85289): 3.9e-75
Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
490 500 510 520 530 540
550 560 570 580
pF1KE0 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
550 560 570 580
>>XP_011524378 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 3971 init1: 3971 opt: 3971 Z-score: 1470.0 bits: 282.0 E(85289): 3.9e-75
Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
490 500 510 520 530 540
550 560 570 580
pF1KE0 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
550 560 570 580
>>XP_016881328 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 3971 init1: 3971 opt: 3971 Z-score: 1470.0 bits: 282.0 E(85289): 3.9e-75
Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
490 500 510 520 530 540
550 560 570 580
pF1KE0 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
550 560 570 580
>>NP_002738 (OMIM: 176949) mitogen-activated protein kin (587 aa)
initn: 3971 init1: 3971 opt: 3971 Z-score: 1470.0 bits: 282.0 E(85289): 3.9e-75
Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
490 500 510 520 530 540
550 560 570 580
pF1KE0 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
550 560 570 580
>>XP_005258356 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 3971 init1: 3971 opt: 3971 Z-score: 1470.0 bits: 282.0 E(85289): 3.9e-75
Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
490 500 510 520 530 540
550 560 570 580
pF1KE0 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
550 560 570 580
>>XP_011524376 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 3971 init1: 3971 opt: 3971 Z-score: 1470.0 bits: 282.0 E(85289): 3.9e-75
Smith-Waterman score: 3971; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAYIVQEYMETDLARLLEQGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQHYS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLD
490 500 510 520 530 540
550 560 570 580
pF1KE0 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
550 560 570 580
>>XP_011524379 (OMIM: 176949) PREDICTED: mitogen-activat (412 aa)
initn: 2793 init1: 2793 opt: 2793 Z-score: 1045.9 bits: 203.0 E(85289): 1.6e-51
Smith-Waterman score: 2793; 99.8% identity (100.0% similar) in 406 aa overlap (182-587:7-412)
160 170 180 190 200 210
pF1KE0 PANIFISTEDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAID
.:::::::::::::::::::::::::::::
XP_011 MKGTLKEGYLSEGLVTKWYRSPRLLLSPNNYTKAID
10 20 30
220 230 240 250 260 270
pF1KE0 MWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLRVMPSFVSSTWEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLRVMPSFVSSTWEVK
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE0 RPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIE
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE0 DEIDDIVLMAANQSQLSNWDTCSSRYPVSLSSDLEWRPDRCQDASEVQRDPRAGSAPLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEIDDIVLMAANQSQLSNWDTCSSRYPVSLSSDLEWRPDRCQDASEVQRDPRAGSAPLAE
160 170 180 190 200 210
400 410 420 430 440 450
pF1KE0 DVQVDPRKDSHSSSERFLEQSHSSMERAFEADYGRSCDYKVGSPSYLDKLLWRDNKPHHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQVDPRKDSHSSSERFLEQSHSSMERAFEADYGRSCDYKVGSPSYLDKLLWRDNKPHHY
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE0 SEPKLILDLSHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEPKLILDLSHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPA
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE0 DDPERRLSASPPGRPAPVDGGASPQFDLDVFISRALKLCTKPEDLPDNKLGDLNGACIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPERRLSASPPGRPAPVDGGASPQFDLDVFISRALKLCTKPEDLPDNKLGDLNGACIPE
340 350 360 370 380 390
580
pF1KE0 HPGDLVQTEAFSKERW
::::::::::::::::
XP_011 HPGDLVQTEAFSKERW
400 410
>>NP_001278968 (OMIM: 176949) mitogen-activated protein (376 aa)
initn: 2598 init1: 2598 opt: 2598 Z-score: 975.8 bits: 189.9 E(85289): 1.3e-47
Smith-Waterman score: 2598; 100.0% identity (100.0% similar) in 376 aa overlap (212-587:1-376)
190 200 210 220 230 240
pF1KE0 KGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLI
::::::::::::::::::::::::::::::
NP_001 MWAAGCILAEMLTGRMLFAGAHELEQMQLI
10 20 30
250 260 270 280 290 300
pF1KE0 LETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRL
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE0 TAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVSL
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE0 SSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDLEWRPDRCQDASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAFE
160 170 180 190 200 210
430 440 450 460 470 480
pF1KE0 ADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADYGRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTGA
220 230 240 250 260 270
490 500 510 520 530 540
pF1KE0 REDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLDV
280 290 300 310 320 330
550 560 570 580
pF1KE0 FISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISRALKLCTKPEDLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
340 350 360 370
>>XP_011524380 (OMIM: 176949) PREDICTED: mitogen-activat (336 aa)
initn: 2120 init1: 2120 opt: 2120 Z-score: 803.5 bits: 157.9 E(85289): 5.1e-38
Smith-Waterman score: 2120; 100.0% identity (100.0% similar) in 303 aa overlap (285-587:34-336)
260 270 280 290 300 310
pF1KE0 ELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSP
::::::::::::::::::::::::::::::
XP_011 TWDMTAALKQKRGNRGTERTCCFGETTEGRAIDFLEKILTFNPMDRLTAEMGLQHPYMSP
10 20 30 40 50 60
320 330 340 350 360 370
pF1KE0 YSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVSLSSDLEWRPDRCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSRYPVSLSSDLEWRPDRCQD
70 80 90 100 110 120
380 390 400 410 420 430
pF1KE0 ASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAFEADYGRSCDYKVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASEVQRDPRAGSAPLAEDVQVDPRKDSHSSSERFLEQSHSSMERAFEADYGRSCDYKVGS
130 140 150 160 170 180
440 450 460 470 480 490
pF1KE0 PSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTGAREDEPASLFLEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSYLDKLLWRDNKPHHYSEPKLILDLSHWKQAAGAPPTATGLADTGAREDEPASLFLEIA
190 200 210 220 230 240
500 510 520 530 540 550
pF1KE0 QWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLDVFISRALKLCTKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWVKSTQGGPEHASPPADDPERRLSASPPGRPAPVDGGASPQFDLDVFISRALKLCTKPE
250 260 270 280 290 300
560 570 580
pF1KE0 DLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
:::::::::::::::::::::::::::::::::
XP_011 DLPDNKLGDLNGACIPEHPGDLVQTEAFSKERW
310 320 330
>>XP_005254596 (OMIM: 602904) PREDICTED: mitogen-activat (721 aa)
initn: 1542 init1: 968 opt: 1791 Z-score: 680.8 bits: 136.3 E(85289): 3.5e-31
Smith-Waterman score: 1947; 53.9% identity (74.7% similar) in 608 aa overlap (1-586:1-574)
10 20 30 40 50 60
pF1KE0 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
:::: . . ...:.:::.:..:..::: : ::::.::::. ..::.:::.:.: .:.:
XP_005 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
10 20 30 40 50 60
70 80 90 100 110
pF1KE0 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQ---GELFKFSVAYIVQEYMETDLARLLE
::::::::::::::::::::.:.:::.:..: : : ... .:::::::::::: .::
XP_005 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 QGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQ
:: : ::::.:::::::::::::::::::::::::::.::.::::::::::::::::.:
XP_005 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 HYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQ
::::::.::::::::::::::::::::::::::::::::::.::::::. ::::::::::
XP_005 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 MQLILETIPVIREEDKDELLRVMPSFVSSTW-EVKRPLRKLLPEVNSEAIDFLEKILTFN
::::::.:::..:::..::: :.: .. . : ..:: .::: .. ::.::::.::::.
XP_005 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 PMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSR
:::::::: .:.::::: :: : ::: :.:::.::::.:::.:: ..:.. ::. :
XP_005 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWE----R
310 320 330 340 350
360 370 380 390 400 410
pF1KE0 YPVSLSSDLEWRPDRCQDASEVQRDPRAGS-APLAEDVQVDPRKDSHSSSERFLEQ----
: :. .: : .::: :::: : . :.::::::: .. :..::.
XP_005 YHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFD
360 370 380 390 400 410
420 430 440 450 460
pF1KE0 SHSSMERAFE-ADY----------GRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDL
.. : : .. .:. ...:.::. : ::::.:.::... .:: :::::.::
XP_005 TNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDL
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE0 SHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSA
:.::. .. . :. .. : ::. : . :.:: ::. .
XP_005 SNWKE------------QSKEKSDKKGKSKCERNGLVKA-QIALEEASQQLAGKEREKNQ
480 490 500 510 520
530 540 550 560 570
pF1KE0 SPPGRPAPVDGGASPQFDLDVFISRALKLCTK--PEDLPDNKLGDLNGACIPEHPGDLVQ
. ::.: ::. ...: .. : :. : ::.:::.. . .:.
XP_005 G---------------FDFDSFIAGTIQLSSQHEPTDVVD-KLNDLNSSVSQLELKSLI-
530 540 550 560
580
pF1KE0 TEAFSKERW
... :.:.
XP_005 SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENTYT
570 580 590 600 610 620
587 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:20:31 2016 done: Sun Nov 6 06:20:33 2016
Total Scan time: 9.670 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]