Result of FASTA (ccds) for
pFN21AE0973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0973, 545 aa
1>>>pF1KE0973 545 - 545 aa - 545 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0018+/-0.0011; mu= 4.9634+/- 0.066
mean_var=341.1333+/-72.782, 0's: 0 Z-trim(112.5): 641 B-trim: 0 in 0/53
Lambda= 0.069440
statistics sampled from 12492 (13257) to 12492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.407), width: 16
Scan time: 3.420
The best scores are: opt bits E(32554)
CCDS42770.1 STK39 gene_id:27347|Hs108|chr2 ( 545) 3582 373.0 5.1e-103
CCDS2675.1 OXSR1 gene_id:9943|Hs108|chr3 ( 527) 2081 222.6 9.2e-58
CCDS7148.1 MYO3A gene_id:53904|Hs108|chr10 (1616) 650 79.8 2.7e-14
CCDS58707.1 MAP4K3 gene_id:8491|Hs108|chr2 ( 873) 599 74.4 6.2e-13
CCDS1803.1 MAP4K3 gene_id:8491|Hs108|chr2 ( 894) 599 74.4 6.3e-13
CCDS76334.1 SLK gene_id:9748|Hs108|chr10 (1204) 587 73.4 1.8e-12
CCDS7553.1 SLK gene_id:9748|Hs108|chr10 (1235) 587 73.4 1.8e-12
CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2 (1165) 579 72.5 3e-12
CCDS34290.1 STK10 gene_id:6793|Hs108|chr5 ( 968) 577 72.2 3.1e-12
CCDS56130.1 MAP4K4 gene_id:9448|Hs108|chr2 (1239) 579 72.6 3.1e-12
CCDS81582.1 MAP4K2 gene_id:5871|Hs108|chr11 ( 812) 575 71.9 3.2e-12
CCDS74546.1 MAP4K4 gene_id:9448|Hs108|chr2 (1273) 579 72.6 3.2e-12
CCDS8082.1 MAP4K2 gene_id:5871|Hs108|chr11 ( 820) 575 72.0 3.2e-12
CCDS46446.1 MYO3B gene_id:140469|Hs108|chr2 (1314) 563 71.0 9.8e-12
CCDS42773.1 MYO3B gene_id:140469|Hs108|chr2 (1341) 563 71.0 9.9e-12
CCDS13341.1 STK4 gene_id:6789|Hs108|chr20 ( 487) 553 69.5 1.1e-11
CCDS47900.1 STK3 gene_id:6788|Hs108|chr8 ( 491) 547 68.9 1.6e-11
CCDS59108.1 STK3 gene_id:6788|Hs108|chr8 ( 519) 547 68.9 1.7e-11
CCDS45589.1 MINK1 gene_id:50488|Hs108|chr17 (1303) 547 69.4 3e-11
CCDS45590.1 MINK1 gene_id:50488|Hs108|chr17 (1312) 547 69.4 3e-11
CCDS45588.1 MINK1 gene_id:50488|Hs108|chr17 (1332) 547 69.4 3e-11
CCDS65305.1 NRK gene_id:203447|Hs108|chrX (1582) 539 68.7 5.8e-11
CCDS54673.1 TNIK gene_id:23043|Hs108|chr3 (1268) 532 67.9 8.3e-11
CCDS54674.1 TNIK gene_id:23043|Hs108|chr3 (1276) 532 67.9 8.3e-11
CCDS54677.1 TNIK gene_id:23043|Hs108|chr3 (1297) 532 67.9 8.4e-11
CCDS54678.1 TNIK gene_id:23043|Hs108|chr3 (1305) 532 67.9 8.4e-11
CCDS54675.1 TNIK gene_id:23043|Hs108|chr3 (1323) 532 67.9 8.5e-11
CCDS54676.1 TNIK gene_id:23043|Hs108|chr3 (1331) 532 67.9 8.5e-11
CCDS54679.1 TNIK gene_id:23043|Hs108|chr3 (1352) 532 67.9 8.6e-11
CCDS46956.1 TNIK gene_id:23043|Hs108|chr3 (1360) 532 67.9 8.6e-11
>>CCDS42770.1 STK39 gene_id:27347|Hs108|chr2 (545 aa)
initn: 3582 init1: 3582 opt: 3582 Z-score: 1963.0 bits: 373.0 E(32554): 5.1e-103
Smith-Waterman score: 3582; 100.0% identity (100.0% similar) in 545 aa overlap (1-545:1-545)
10 20 30 40 50 60
pF1KE0 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
490 500 510 520 530 540
pF1KE0 QLSVS
:::::
CCDS42 QLSVS
>>CCDS2675.1 OXSR1 gene_id:9943|Hs108|chr3 (527 aa)
initn: 2537 init1: 2076 opt: 2081 Z-score: 1150.5 bits: 222.6 E(32554): 9.2e-58
Smith-Waterman score: 2520; 74.6% identity (88.2% similar) in 524 aa overlap (51-545:5-527)
30 40 50 60 70 80
pF1KE0 TAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAA
..:. : : :: ::::::::::::::::::
CCDS26 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAA
10 20 30
90 100 110 120 130 140
pF1KE0 LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKL
: :..:.:::::::::::::::::::::::::::: :::.:.:::::::::::::::::
CCDS26 YCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
:::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::.:::::::
CCDS26 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILL
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
::::::::::::::::::::::.::::::::::::::::::::::::::::::::.::::
CCDS26 GEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
:::::::::::::::::::::::::::::::.:::::.::::.:::::::::..::::::
CCDS26 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE0 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
:: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::.:::::::
CCDS26 DPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDG
280 290 300 310 320 330
390 400 410 420
pF1KE0 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKEE--NPEIAVSASTI------PEQIQS----
:::::::.::.:::::::.:: .: :::: : :. ... . ::::..
CCDS26 GWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQ
340 350 360 370 380 390
430 440 450 460 470
pF1KE0 ----LSVHDSQG--PPNANEDYREASSCA-----------VNLVLRLRNSRKELNDIRFE
.... .: ::.: : . :.. . ..::::::::.:::::::::
CCDS26 PAGQIATQPTQVSLPPTA-EPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFE
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE0 FTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIP
::::::::.::::::.:::::::.:.:::::::::::..:.. ...::::::: .::.::
CCDS26 FTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIP
460 470 480 490 500 510
540
pF1KE0 DEVKLIGFAQLSVS
:. :::::::::.:
CCDS26 DDGKLIGFAQLSIS
520
>>CCDS7148.1 MYO3A gene_id:53904|Hs108|chr10 (1616 aa)
initn: 518 init1: 190 opt: 650 Z-score: 370.2 bits: 79.8 E(32554): 2.7e-14
Smith-Waterman score: 650; 36.9% identity (63.9% similar) in 371 aa overlap (56-404:14-366)
30 40 50 60 70 80
pF1KE0 AAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPR
.: :..:. :.::.:. . : .: :
CCDS71 MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKN
10 20 30 40
90 100 110 120 130
pF1KE0 QERVAIKRINLEKCQTSMDELLKEIQAMSQCS-HPNVVTYYTSFVVKDE-----LWLVMK
...:.: :. . .:. : . .. : ::::: .: . ::. ::::..
CCDS71 GQKAAVK--ILDPIHDIDEEIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLE
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE0 LLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNIL
: ::::. :..: ...:::. . : .:: ::.:.: ::..:: : ::::.:..:::
CCDS71 LCSGGSVTDLVKGFLKRGER----MSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNIL
110 120 130 140 150
200 210 220 230 240 250
pF1KE0 LGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM--EQV--RGYDFKAD
: .:.:...:::::: :.. ::.. :.: :::: ::::::. :: :: . :
CCDS71 LTTEGGVKLVDFGVSAQLTS----TRHR-RNTSVGTPFWMAPEVIACEQQLDTTYDARCD
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE0 MWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLS
::.:::::::. : : ::..:. .: :: :. . :. .. : ..:
CCDS71 TWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLR----QPEL---WSAEFNDFIS
220 230 240 250 260
320 330 340 350 360 370
pF1KE0 LCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQ---RAKKVRR--VPGS
:: :: ::::..:::. ::. . .... ...: ::. : : ..:.:: . .
CCDS71 KCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCMGGTEKARRERIHTK
270 280 290 300 310 320
380 390 400 410 420
pF1KE0 SGHLHKTEDGDWEWSDDE-----MDEK--SEEGKAAFSQEKSRRVKEENPEIAVSASTIP
.:.... .. . :: .::. ::. . .:...
CCDS71 KGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLG
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE0 EQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVS
CCDS71 LYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLV
390 400 410 420 430 440
>>CCDS58707.1 MAP4K3 gene_id:8491|Hs108|chr2 (873 aa)
initn: 675 init1: 186 opt: 599 Z-score: 345.6 bits: 74.4 E(32554): 6.2e-13
Smith-Waterman score: 638; 39.9% identity (66.7% similar) in 303 aa overlap (60-356:13-293)
30 40 50 60 70 80
pF1KE0 AATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERV
.. .:: . ::::. . : : : .
CCDS58 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELA
10 20 30 40
90 100 110 120 130 140
pF1KE0 AIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDI
::: :.:: . .. . .:: :..:.:::.:.:. :.. .:.::. :.. .:::. ::
CCDS58 AIKVIKLEPGE-DFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDI
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE0 IKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIA
: .: : : :: . .:.:.:: ::: .:..:::.:..:::: ..: :..:
CCDS58 Y--------HVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLA
110 120 130 140 150
210 220 230 240 250 260
pF1KE0 DFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEV--MEQVRGYDFKADMWSFGITAIELA
:::::: .. . ... ::.:.::: :::::: .:. ::. :.:. ::::::::
CCDS58 DFGVSAQIT--ATIAK---RKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELA
160 170 180 190 200
270 280 290 300 310 320
pF1KE0 TGAAPYHKYPPMKVLMLTLQND--PPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKR
:. ::..:.: ... :: : :. :: ...::...... : :.:.::
CCDS58 ELQPPMFDLHPMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKR
210 220 230 240 250 260
330 340 350 360 370 380
pF1KE0 PTAAELLKCKFFQKAKNREYLIEKLLTRT--PDIAQRAKKVRRVPGSSGHLHKTEDGDWE
::: .::. : . .: :: :: .. ::
CCDS58 PTAEKLLQHPFVTQHLTRSLAIE-LLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSR
270 280 290 300 310 320
390 400 410 420 430 440
pF1KE0 WSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANED
CCDS58 NVREEKTRSEITFGQVKFDPPLRKETEPHHELDLQLEYGQGHQGGYFLGANKSLLKSVEE
330 340 350 360 370 380
>>CCDS1803.1 MAP4K3 gene_id:8491|Hs108|chr2 (894 aa)
initn: 675 init1: 186 opt: 599 Z-score: 345.5 bits: 74.4 E(32554): 6.3e-13
Smith-Waterman score: 638; 39.9% identity (66.7% similar) in 303 aa overlap (60-356:13-293)
30 40 50 60 70 80
pF1KE0 AATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERV
.. .:: . ::::. . : : : .
CCDS18 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELA
10 20 30 40
90 100 110 120 130 140
pF1KE0 AIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDI
::: :.:: . .. . .:: :..:.:::.:.:. :.. .:.::. :.. .:::. ::
CCDS18 AIKVIKLEPGE-DFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDI
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE0 IKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIA
: .: : : :: . .:.:.:: ::: .:..:::.:..:::: ..: :..:
CCDS18 Y--------HVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLA
110 120 130 140 150
210 220 230 240 250 260
pF1KE0 DFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEV--MEQVRGYDFKADMWSFGITAIELA
:::::: .. . ... ::.:.::: :::::: .:. ::. :.:. ::::::::
CCDS18 DFGVSAQIT--ATIAK---RKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELA
160 170 180 190 200
270 280 290 300 310 320
pF1KE0 TGAAPYHKYPPMKVLMLTLQND--PPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKR
:. ::..:.: ... :: : :. :: ...::...... : :.:.::
CCDS18 ELQPPMFDLHPMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKR
210 220 230 240 250 260
330 340 350 360 370 380
pF1KE0 PTAAELLKCKFFQKAKNREYLIEKLLTRT--PDIAQRAKKVRRVPGSSGHLHKTEDGDWE
::: .::. : . .: :: :: .. ::
CCDS18 PTAEKLLQHPFVTQHLTRSLAIE-LLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSR
270 280 290 300 310 320
390 400 410 420 430 440
pF1KE0 WSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANED
CCDS18 NVREEKTRSEITFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYG
330 340 350 360 370 380
>>CCDS76334.1 SLK gene_id:9748|Hs108|chr10 (1204 aa)
initn: 530 init1: 194 opt: 587 Z-score: 337.6 bits: 73.4 E(32554): 1.8e-12
Smith-Waterman score: 590; 31.0% identity (60.2% similar) in 397 aa overlap (61-446:32-399)
40 50 60 70 80 90
pF1KE0 ATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVA
: .:. .:.:: . : : : . .:
CCDS76 SFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAA
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE0 IKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDII
: :. : . ... . ::. ...:.:::.: .: ...::..... .::.. : .
CCDS76 AKVIDT-KSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAV-DAV
70 80 90 100 110
160 170 180 190 200 210
pF1KE0 KYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIAD
..: : :. : .. :..:..:.::: : :::::::::::. ::....::
CCDS76 MLELERP------LTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLAD
120 130 140 150 160 170
220 230 240 250 260
pF1KE0 FGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM----EQVRGYDFKADMWSFGITAIEL
::::: .. . : .:.::: ::::::. . : ::.:::.::.::: ::.
CCDS76 FGVSA-----KNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM
180 190 200 210 220
270 280 290 300 310 320
pF1KE0 ATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRP
: :.:. ::.::. ...:::: . ......:. .:. ::.:. . :
CCDS76 AEIEPPHHELNPMRVLLKIAKSEPPTLA-------QPSRWSSNFKDFLKKCLEKNVDARW
230 240 250 260 270 280
330 340 350 360 370
pF1KE0 TAAELLKCKFFQKAKN---REYLIEKLLTRTPDIAQRAKKVRRVPGSSGHL----HKTED
:...::. : .: :: . : : .. . .:. . . . : : .
CCDS76 TTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEV-EDGKEEDEEEETENSLPIPASKRAS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE0 GDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPN
.: ...: :. :.. : . . :..... : : .... . :. .. : .
CCDS76 SDLSIASSEEDKLSQN--ACILESVSEKTERSNSEDKLNSKILNEK------PTTDEPEK
350 360 370 380 390
440 450 460 470 480 490
pF1KE0 ANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVI
: :: :
CCDS76 AVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKE
400 410 420 430 440 450
>>CCDS7553.1 SLK gene_id:9748|Hs108|chr10 (1235 aa)
initn: 530 init1: 194 opt: 587 Z-score: 337.4 bits: 73.4 E(32554): 1.8e-12
Smith-Waterman score: 590; 31.0% identity (60.2% similar) in 397 aa overlap (61-446:32-399)
40 50 60 70 80 90
pF1KE0 ATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVA
: .:. .:.:: . : : : . .:
CCDS75 SFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAA
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE0 IKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDII
: :. : . ... . ::. ...:.:::.: .: ...::..... .::.. : .
CCDS75 AKVIDT-KSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAV-DAV
70 80 90 100 110
160 170 180 190 200 210
pF1KE0 KYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIAD
..: : :. : .. :..:..:.::: : :::::::::::. ::....::
CCDS75 MLELERP------LTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLAD
120 130 140 150 160 170
220 230 240 250 260
pF1KE0 FGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM----EQVRGYDFKADMWSFGITAIEL
::::: .. . : .:.::: ::::::. . : ::.:::.::.::: ::.
CCDS75 FGVSA-----KNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEM
180 190 200 210 220
270 280 290 300 310 320
pF1KE0 ATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRP
: :.:. ::.::. ...:::: . ......:. .:. ::.:. . :
CCDS75 AEIEPPHHELNPMRVLLKIAKSEPPTLA-------QPSRWSSNFKDFLKKCLEKNVDARW
230 240 250 260 270 280
330 340 350 360 370
pF1KE0 TAAELLKCKFFQKAKN---REYLIEKLLTRTPDIAQRAKKVRRVPGSSGHL----HKTED
:...::. : .: :: . : : .. . .:. . . . : : .
CCDS75 TTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEV-EDGKEEDEEEETENSLPIPASKRAS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE0 GDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPN
.: ...: :. :.. : . . :..... : : .... . :. .. : .
CCDS75 SDLSIASSEEDKLSQN--ACILESVSEKTERSNSEDKLNSKILNEK------PTTDEPEK
350 360 370 380 390
440 450 460 470 480 490
pF1KE0 ANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVI
: :: :
CCDS75 AVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKE
400 410 420 430 440 450
>>CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2 (1165 aa)
initn: 535 init1: 168 opt: 579 Z-score: 333.4 bits: 72.5 E(32554): 3e-12
Smith-Waterman score: 587; 34.9% identity (62.0% similar) in 361 aa overlap (46-392:5-331)
20 30 40 50 60 70
pF1KE0 QAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDA---YELQEVIGSG
.:: . . :: .:: ::.:.:
CCDS82 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNG
10 20 30
80 90 100 110 120 130
pF1KE0 ATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHP-NVVTYYTSFVVK
. . : . . .::: ... . .:. ::. ... :: :..::: .:. :
CCDS82 TYGQVYKGRHVKTGQLAAIKVMDV--TEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKK
40 50 60 70 80 90
140 150 160 170 180
pF1KE0 ------DELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHR
:.:::::.. ..::. :..: . :...:.: :: : .:.:.:: .::
CCDS82 SPPGHDDQLWLVMEFCGAGSITDLVK------NTKGNTLKEDWIAYISREILRGLAHLHI
100 110 120 130 140
190 200 210 220 230 240
pF1KE0 NGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVME
. ::::.:. :.:: :.. :...:::::: : : : .. :.::.::: ::::::.
CCDS82 HHVIHRDIKGQNVLLTENAEVKLVDFGVSAQL----DRTVGR-RNTFIGTPYWMAPEVIA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 QVRG----YDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKE
.. ::...:.:: ::::::.: :: : . ::..:.: .: :: :..
CCDS82 CDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS------
210 220 230 240 250
310 320 330 340 350 360
pF1KE0 MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRA
::..:.: ... :: :. .::.. .::: :.. :.. .. . : .:.
CCDS82 --KKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNER----QVRIQLKDHIDRT
260 270 280 290 300
370 380 390 400 410 420
pF1KE0 KKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAST
.: : :. .:: .:.: .: .:.
CCDS82 RKKR------GEKDETE---YEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE0 IPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADG
CCDS82 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
370 380 390 400 410 420
>>CCDS34290.1 STK10 gene_id:6793|Hs108|chr5 (968 aa)
initn: 552 init1: 180 opt: 577 Z-score: 333.2 bits: 72.2 E(32554): 3.1e-12
Smith-Waterman score: 599; 31.2% identity (58.1% similar) in 439 aa overlap (61-480:31-432)
40 50 60 70 80
pF1KE0 ATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIG---SGATAVVQAALCKPRQE
: :. :..: .:: . : : :
CCDS34 MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGA
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE0 RVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSML
.: : :. : . ... . ::. .. :.:: .: .. .::..... ::..
CCDS34 LAAAKVIET-KSEEELEDYIVEIEILATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGAV-
70 80 90 100 110
150 160 170 180 190 200
pF1KE0 DIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQ
: : ..:: : : : .. ...::.:..:: . :::::::::.:. .:...
CCDS34 DAIMLELDRG------LTEPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIR
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE0 IADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM--EQVRG--YDFKADMWSFGITA
.::::::: .. . : .:.::: ::::::. : .. ::.:::.::.:::
CCDS34 LADFGVSA-----KNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITL
180 190 200 210 220
270 280 290 300 310 320
pF1KE0 IELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPS
::.: :.:. ::.::. ..::::: : .:.. :: .:.. :.:.:
CCDS34 IEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTP-------SKWSVEFRDFLKIALDKNPE
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE0 KRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG-DW
::.::.::. : .. . . : : .:. .: ... ::: :
CCDS34 TRPSAAQLLEHPFVSSITSNKALREL-------VAEAKAEV---------MEEIEDGRDE
290 300 310 320
390 400 410 420 430
pF1KE0 EWSDDEMDEKSE-EGKAAFSQEKSR-RVKEENP-EIAVSASTIPEQIQSLSVHDSQGPPN
.: .: : :... :.: : .. ..: : . :. : : :. ::.. . :.
CCDS34 GEEEDAVDAASTLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQD-SVNEPCSQPS
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE0 ANEDYREASSCAVN--------LVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGL
.... . .: .: . . ::.:: : :.. . ...:.
CCDS34 GDRSLQTTSPPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEKQVAEQGGDLSPAANR
390 400 410 420 430 440
500 510 520 530 540
pF1KE0 VDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
CCDS34 SQKASQSRPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCTSESMDYGTNLS
450 460 470 480 490 500
>>CCDS56130.1 MAP4K4 gene_id:9448|Hs108|chr2 (1239 aa)
initn: 535 init1: 168 opt: 579 Z-score: 333.1 bits: 72.6 E(32554): 3.1e-12
Smith-Waterman score: 587; 34.9% identity (62.0% similar) in 361 aa overlap (46-392:5-331)
20 30 40 50 60 70
pF1KE0 QAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDA---YELQEVIGSG
.:: . . :: .:: ::.:.:
CCDS56 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNG
10 20 30
80 90 100 110 120 130
pF1KE0 ATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHP-NVVTYYTSFVVK
. . : . . .::: ... . .:. ::. ... :: :..::: .:. :
CCDS56 TYGQVYKGRHVKTGQLAAIKVMDV--TEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKK
40 50 60 70 80 90
140 150 160 170 180
pF1KE0 ------DELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHR
:.:::::.. ..::. :..: . :...:.: :: : .:.:.:: .::
CCDS56 SPPGHDDQLWLVMEFCGAGSITDLVK------NTKGNTLKEDWIAYISREILRGLAHLHI
100 110 120 130 140
190 200 210 220 230 240
pF1KE0 NGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVME
. ::::.:. :.:: :.. :...:::::: : : : .. :.::.::: ::::::.
CCDS56 HHVIHRDIKGQNVLLTENAEVKLVDFGVSAQL----DRTVGR-RNTFIGTPYWMAPEVIA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE0 QVRG----YDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKE
.. ::...:.:: ::::::.: :: : . ::..:.: .: :: :..
CCDS56 CDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS------
210 220 230 240 250
310 320 330 340 350 360
pF1KE0 MMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRA
::..:.: ... :: :. .::.. .::: :.. :.. .. . : .:.
CCDS56 --KKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNER----QVRIQLKDHIDRT
260 270 280 290 300
370 380 390 400 410 420
pF1KE0 KKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAST
.: : :. .:: .:.: .: .:.
CCDS56 RKKR------GEKDETE---YEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQ
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE0 IPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADG
CCDS56 QENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR
370 380 390 400 410 420
545 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:13:02 2016 done: Mon Nov 7 16:13:02 2016
Total Scan time: 3.420 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]