Result of FASTA (ccds) for
pFN21AE0899
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0899, 1246 aa
1>>>pF1KE0899 1246 - 1246 aa - 1246 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9401+/-0.000953; mu= 11.6518+/- 0.058
mean_var=161.8251+/-31.477, 0's: 0 Z-trim(111.0): 45 B-trim: 0 in 0/52
Lambda= 0.100821
statistics sampled from 11979 (12010) to 11979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.369), width: 16
Scan time: 5.100
The best scores are: opt bits E(32554)
CCDS4533.1 JARID2 gene_id:3720|Hs108|chr6 (1246) 8374 1230.9 0
CCDS58996.1 JARID2 gene_id:3720|Hs108|chr6 (1074) 7247 1067.0 0
CCDS55417.1 KDM5C gene_id:8242|Hs108|chrX (1379) 417 73.6 3.9e-12
CCDS65269.1 KDM5C gene_id:8242|Hs108|chrX (1559) 417 73.6 4.3e-12
CCDS14351.1 KDM5C gene_id:8242|Hs108|chrX (1560) 417 73.6 4.3e-12
CCDS55555.1 KDM5D gene_id:8284|Hs108|chrY (1570) 404 71.7 1.6e-11
CCDS55554.1 KDM5D gene_id:8284|Hs108|chrY (1482) 403 71.6 1.7e-11
CCDS14794.1 KDM5D gene_id:8284|Hs108|chrY (1539) 403 71.6 1.8e-11
>>CCDS4533.1 JARID2 gene_id:3720|Hs108|chr6 (1246 aa)
initn: 8374 init1: 8374 opt: 8374 Z-score: 6586.9 bits: 1230.9 E(32554): 0
Smith-Waterman score: 8374; 100.0% identity (100.0% similar) in 1246 aa overlap (1-1246:1-1246)
10 20 30 40 50 60
pF1KE0 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 HKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 EVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 LNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 KAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 LNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 LINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 KEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 QLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 PAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 SILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 EDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE0 CGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLST
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE0 ISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE0 ICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240
pF1KE0 SGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS
1210 1220 1230 1240
>>CCDS58996.1 JARID2 gene_id:3720|Hs108|chr6 (1074 aa)
initn: 7247 init1: 7247 opt: 7247 Z-score: 5701.9 bits: 1067.0 E(32554): 0
Smith-Waterman score: 7247; 100.0% identity (100.0% similar) in 1074 aa overlap (173-1246:1-1074)
150 160 170 180 190 200
pF1KE0 QISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNA
::::::::::::::::::::::::::::::
CCDS58 MVYFGSSQDEEEVEEEDDETEDVKTATNNA
10 20 30
210 220 230 240 250 260
pF1KE0 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRR
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSA
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKR
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRA
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE0 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRP
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE0 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWG
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE0 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 PNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLAD
460 470 480 490 500 510
690 700 710 720 730 740
pF1KE0 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTE
520 530 540 550 560 570
750 760 770 780 790 800
pF1KE0 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEE
580 590 600 610 620 630
810 820 830 840 850 860
pF1KE0 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DKGVLNDFHKCIYKGRSVSLTTFYRTARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVA
640 650 660 670 680 690
870 880 890 900 910 920
pF1KE0 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMV
700 710 720 730 740 750
930 940 950 960 970 980
pF1KE0 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 FSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESN
760 770 780 790 800 810
990 1000 1010 1020 1030 1040
pF1KE0 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFE
820 830 840 850 860 870
1050 1060 1070 1080 1090 1100
pF1KE0 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEA
880 890 900 910 920 930
1110 1120 1130 1140 1150 1160
pF1KE0 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCL
940 950 960 970 980 990
1170 1180 1190 1200 1210 1220
pF1KE0 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ECALRHVEKQKSCRGLKLMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRK
1000 1010 1020 1030 1040 1050
1230 1240
pF1KE0 RATVDVPPSRLSASSSSKSASSSS
::::::::::::::::::::::::
CCDS58 RATVDVPPSRLSASSSSKSASSSS
1060 1070
>>CCDS55417.1 KDM5C gene_id:8242|Hs108|chrX (1379 aa)
initn: 475 init1: 174 opt: 417 Z-score: 331.3 bits: 73.6 E(32554): 3.9e-12
Smith-Waterman score: 553; 24.7% identity (51.2% similar) in 722 aa overlap (556-1196:13-696)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
CCDS55 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630
pF1KE0 MCRVIPPP------DWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQG
.:.. :: .. :: . :.. : .:. : :. : ...: .
CCDS55 ICKIRPPAIVVEEGGYEAICK---DRRWARVAQ---RLNYPPGKNIGSL--LRSHYER--
50 60 70 80 90
640 650 660 670 680
pF1KE0 ITMDELPLIGGCELDLACFFR-LINEMGG---------MQQVTDLKKWNKLADMLRIPRT
:.. .: .: . : : . :: ..: .. .:.:. . : :
CCDS55 IVYPYEMYQSGANL-VQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGR--RAKRL
100 110 120 130 140
690 700 710 720 730 740
pF1KE0 AQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKR--KGP-------LEGH
: .. . :. .. . . .. . . :.:. .:: .. .
CCDS55 QPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEE
150 160 170 180 190 200
750 760 770 780 790
pF1KE0 TENDHHKFHPLPR--FEPKNGLIHGVAPRNGFRSKLKEV-GQAQ-LKTGRRRLFAQEKEV
.: . :. .: :. : :. : . . .:.. ..:: ... :. .. :
CCDS55 LGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDED
210 220 230 240 250 260
800 810 820
pF1KE0 VKEEEEDKGVLNDFH-------------------KCIYK---------G-----RSVSLT
: : : ...: ::.. : : .:
CCDS55 DKLLLCD-GCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQ
270 280 290 300 310 320
830 840 850 860 870
pF1KE0 TFYRTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPV
.: . : .. . :. . .:.: .:.:.::::. . :.:. : . .. ::::::
CCDS55 SFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPV
330 340 350 360 370 380
880 890 900 910 920 930
pF1KE0 GKS--------EPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSR
. : : .. ::::.:.: :.: :..: . :. .::: .:::::. :: .
CCDS55 SDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCW-H
390 400 410 420 430 440
940 950 960 970 980
pF1KE0 DQNHLPY-IDYLHTGADCIWYCIPAEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISP
..: : :.::: : :: .:. ..::.:.. : .. : : . . ....:
CCDS55 IEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDL-LHQLVTLMNP
450 460 470 480 490 500
990 1000 1010 1020 1030 1040
pF1KE0 EVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEM
..: ..:. : :: : .:.::. :: .. : ::. .:.:.: :..: : . ...
CCDS55 NTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHY
510 520 530 540 550 560
1050 1060 1070 1080 1090 1100
pF1KE0 KRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSS
.: . :: :.:. ..: : .: . ... . . . : : :. :.: :. .
CCDS55 RRLRRYCVFSHEELICKMA-ACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEA
570 580 590 600 610 620
1110 1120 1130 1140 1150 1160
pF1KE0 ARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECAL
: . . : .::.: :. :.:: .. . . . ::
CCDS55 ER-----------------EAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----
630 640 650 660
1170 1180 1190 1200 1210 1220
pF1KE0 RHVEKQKSCRGLK--LMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRA
:.. .: . . : ::: ... ......
CCDS55 SHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSL
670 680 690 700 710 720
1230 1240
pF1KE0 TVDVPPSRLSASSSSKSASSSS
CCDS55 EELRALESEARERRFPNSELLQQLKNCLSEAEACVSRALGLVSGQEAGPHRVAGLQMTLT
730 740 750 760 770 780
>>CCDS65269.1 KDM5C gene_id:8242|Hs108|chrX (1559 aa)
initn: 508 init1: 174 opt: 417 Z-score: 330.5 bits: 73.6 E(32554): 4.3e-12
Smith-Waterman score: 670; 24.8% identity (50.6% similar) in 775 aa overlap (556-1196:13-762)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
CCDS65 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630 640
pF1KE0 MCRVIPPPDWRPECKLN-DEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDE
.:.. :: ::.: .. :..::. .::....: . ... : : : . :: .. .
CCDS65 ICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSL-K
50 60 70 80 90 100
650 660 670 680 690
pF1KE0 LPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIP---------RTAQDRLA
.: . ::: . ... : ::.. . ..: ..:. : : :. .:..
CCDS65 IPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIV
110 120 130 140 150 160
700 710 720 730 740
pF1KE0 KLQEAYCQYLLSYDSLSPEEHRRLEKE-----VLMEKEILE----------KRKGPLEGH
: : . . : .... .:: . ... . :: :
CCDS65 YPYEMYQSGANLVCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEP
170 180 190 200 210 220
750 760 770 780
pF1KE0 TENDHHKFHPLPRFE-----PKNGLIHGVAPRNGFRSKLKEV--------------GQAQ
::.: .: : ... :: . .: . .:.: :: :...
CCDS65 TEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVK
230 240 250 260 270 280
790 800
pF1KE0 LKTGRRRLFAQEKEVVKE---------------------------------EEEDKGVLN
... . : . :: ... .:.:: .:
CCDS65 VESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLC
290 300 310 320 330 340
810 820 830
pF1KE0 D-----FH-------------------KCIYK---------G-----RSVSLTTFYRTAR
: .: ::.. : : .: .: . :
CCDS65 DGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMAD
350 360 370 380 390 400
840 850 860 870 880
pF1KE0 NIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPVGKS----
.. . :. . .:.: .:.:.::::. . :.:. : . .. ::::::. :
CCDS65 SFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHL
410 420 430 440 450 460
890 900 910 920 930
pF1KE0 ----EPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSRDQNHLPY
: .. ::::.:.: :.: :..: . :. .::: .:::::. :: . ..: :
CCDS65 TPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCW-HIEDHWSY
470 480 490 500 510 520
940 950 960 970 980 990
pF1KE0 -IDYLHTGADCIWYCIPAEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISPEVLCKEG
:.::: : :: .:. ..::.:.. : .. : : . . ....:..: ..:
CCDS65 SINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDL-LHQLVTLMNPNTLMSHG
530 540 550 560 570
1000 1010 1020 1030 1040 1050
pF1KE0 IKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAK
. : :: : .:.::. :: .. : ::. .:.:.: :..: : . ....: .
CCDS65 VPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYC
580 590 600 610 620 630
1060 1070 1080 1090 1100 1110
pF1KE0 PFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHD
:: :.:. ..: : .: . ... . . . : : :. :.: :. . :
CCDS65 VFSHEELICKMA-ACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAER-----
640 650 660 670 680 690
1120 1130 1140 1150 1160 1170
pF1KE0 GSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECALRHVEKQK
. . : .::.: :. :.:: .. . . . :: :..
CCDS65 ------------EAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----SHINDLC
700 710 720 730
1180 1190 1200 1210 1220 1230
pF1KE0 SCRGLK--LMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPS
.: . . : ::: ... ......
CCDS65 KCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALE
740 750 760 770 780 790
>>CCDS14351.1 KDM5C gene_id:8242|Hs108|chrX (1560 aa)
initn: 508 init1: 174 opt: 417 Z-score: 330.5 bits: 73.6 E(32554): 4.3e-12
Smith-Waterman score: 668; 24.9% identity (50.6% similar) in 776 aa overlap (556-1196:13-763)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
CCDS14 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630 640
pF1KE0 MCRVIPPPDWRPECKLN-DEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDE
.:.. :: ::.: .. :..::. .::....: . ... : : : . :: .. .
CCDS14 ICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSL-K
50 60 70 80 90 100
650 660 670 680 690
pF1KE0 LPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIP---------RTAQDRLA
.: . ::: . ... : ::.. . ..: ..:. : : :. .:..
CCDS14 IPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIV
110 120 130 140 150 160
700 710 720 730
pF1KE0 KLQEAYCQYL-LSYDSLSPEEHRRLEKE-----VLMEKEILE----------KRKGPLEG
: : . : . : .... .:: . ... . :: :
CCDS14 YPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPE
170 180 190 200 210 220
740 750 760 770 780
pF1KE0 HTENDHHKFHPLPRFE-----PKNGLIHGVAPRNGFRSKLKEV--------------GQA
::.: .: : ... :: . .: . .:.: :: :..
CCDS14 PTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDV
230 240 250 260 270 280
790 800
pF1KE0 QLKTGRRRLFAQEKEVVKE---------------------------------EEEDKGVL
.... . : . :: ... .:.:: .:
CCDS14 KVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLL
290 300 310 320 330 340
810 820
pF1KE0 ND-----FH-------------------KCIYK---------G-----RSVSLTTFYRTA
: .: ::.. : : .: .: . :
CCDS14 CDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMA
350 360 370 380 390 400
830 840 850 860 870 880
pF1KE0 RNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPVGKS---
.. . :. . .:.: .:.:.::::. . :.:. : . .. ::::::. :
CCDS14 DSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRH
410 420 430 440 450 460
890 900 910 920 930
pF1KE0 -----EPFSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSRDQNHLP
: .. ::::.:.: :.: :..: . :. .::: .:::::. :: . ..:
CCDS14 LTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCW-HIEDHWS
470 480 490 500 510 520
940 950 960 970 980 990
pF1KE0 Y-IDYLHTGADCIWYCIPAEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISPEVLCKE
: :.::: : :: .:. ..::.:.. : .. : : . . ....:..: ..
CCDS14 YSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDL-LHQLVTLMNPNTLMSH
530 540 550 560 570
1000 1010 1020 1030 1040 1050
pF1KE0 GIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIA
:. : :: : .:.::. :: .. : ::. .:.:.: :..: : . ....: .
CCDS14 GVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRY
580 590 600 610 620 630
1060 1070 1080 1090 1100 1110
pF1KE0 KPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSH
:: :.:. ..: : .: . ... . . . : : :. :.: :. . :
CCDS14 CVFSHEELICKMA-ACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAER----
640 650 660 670 680 690
1120 1130 1140 1150 1160 1170
pF1KE0 DGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECALRHVEKQ
. . : .::.: :. :.:: .. . . . :: :..
CCDS14 -------------EAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----SHINDL
700 710 720 730
1180 1190 1200 1210 1220 1230
pF1KE0 KSCRGLK--LMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPP
.: . . : ::: ... ......
CCDS14 CKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRAL
740 750 760 770 780 790
>>CCDS55555.1 KDM5D gene_id:8284|Hs108|chrY (1570 aa)
initn: 507 init1: 174 opt: 404 Z-score: 320.3 bits: 71.7 E(32554): 1.6e-11
Smith-Waterman score: 583; 24.0% identity (49.2% similar) in 803 aa overlap (556-1196:13-784)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
CCDS55 MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630 640
pF1KE0 MCRVIPPPDWRPECKLN-DEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDE
.:.. :: ::.: .. :..::. ..:....: . ... : : : . :: .. .
CCDS55 ICKIRPPADWQPPFAVEVDNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSL-K
50 60 70 80 90 100
650 660 670 680 690 700
pF1KE0 LPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQY
.: . ::: . ... : ::.. . ..: ..:. :. : ... . :. : .
CCDS55 IPNVERKILDLYSLSKIVIEEGGYEAICKDRRWARVAQRLHYP-PGKNIGSLLRSHYERI
110 120 130 140 150 160
710 720 730
pF1KE0 LLSYDSLS-----------PEEHRRLEKE-----VLMEKEILE----------KRKGPLE
. :. .. : ... .:: . ... . :: :
CCDS55 IYPYEMFQSGANHVQCNTHPFDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDP
170 180 190 200 210 220
740 750 760 770 780
pF1KE0 GHTENDHHKFHPLPRFEPKNGLIHGVAPRN---GFRSKLKE--------------VGQAQ
::.: .: :: : :. :.: .:. :. .: :. : . :
CCDS55 EPTEEDIEK-HP----ELKKLQIYGPGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQ
230 240 250 260 270
790 800
pF1KE0 LKTGR--RRLFAQE-------KEVV---------------------KEEEEDK-----GV
: :. :. : .. . .:.:: :
CCDS55 SGGGNVSSTLLKQHLSLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGC
280 290 300 310 320 330
810 820 830
pF1KE0 LNDFH-------------------KCIYK---------G-----RSVSLTTFYRTARNIM
...: ::: : . :: .: . : ..
CCDS55 DDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFGEMADSFK
340 350 360 370 380 390
840 850 860 870 880
pF1KE0 SMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPVGKSE----P-
: :. . .:.: .:.:.:::: . :.:. : . .. ::::::..:. :
CCDS55 SDYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPE
400 410 420 430 440 450
890 900
pF1KE0 ----------------------------------FSRHGWNLTVLPNNTGSILRHLGA-V
.. ::::.:.: :.: :..: .
CCDS55 EKRQSLTVLTRLISSFWAQAVLPPWPPKVLGLQEYATSGWNLNVMPVLDQSVLCHINADI
460 470 480 490 500 510
910 920 930 940 950 960
pF1KE0 PGVTIPWLNIGMVFSTSCWSRDQNHLPY-IDYLHTGADCIWYCIPAEEENKLEDVVHTLL
:. .::: .:::::. :: . ..: : :.::: : :: .:. ..::.:.. :
CCDS55 SGMKVPWLYVGMVFSAFCW-HIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLT
520 530 540 550 560 570
970 980 990 1000 1010 1020
pF1KE0 QA--NGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVS
.. : : . . ....:..: ..:. : :: : .:.::. :: .. : ::. .
CCDS55 PELFDSQPDL-LHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFA
580 590 600 610 620 630
1030 1040 1050 1060 1070 1080
pF1KE0 ETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLD
:.:.: :..: : . ....: . :: :.:. ..: . . .... . ..
CCDS55 EAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFI
640 650 660 670 680 690
1090 1100 1110 1120 1130 1140
pF1KE0 ELRDTELRQRRQLFEAGLHSSARYGSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLC
... : : :. :.: :. . : . . : .::.: :. :
CCDS55 MVQE-ERRLRKALLEKGVTEAER-----------------EAFELLPDDERQCIKCKTTC
700 710 720 730
1150 1160 1170 1180 1190 1200
pF1KE0 YLS-MVVQENENVVFCLECALRHVEKQKSCRGLK--LMYRYDEEQIISLVNQICGKVSGK
.:: .. . . . :: :.. .: . . : ::: ... ......
CCDS55 FLSALACYDCPDGLVCL----SHINDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESF
740 750 760 770 780 790
1210 1220 1230 1240
pF1KE0 NGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS
CCDS55 DTWANKVRVALEVEDGRKRSFEELRALESEARERRFPNSELLQRLKNCLSEVEACIAQVL
800 810 820 830 840 850
>>CCDS55554.1 KDM5D gene_id:8284|Hs108|chrY (1482 aa)
initn: 510 init1: 174 opt: 403 Z-score: 319.8 bits: 71.6 E(32554): 1.7e-11
Smith-Waterman score: 635; 25.2% identity (51.9% similar) in 719 aa overlap (556-1196:13-696)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
CCDS55 MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630 640
pF1KE0 MCRVIPPPDWRPECKLN-DEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDE
.:.. :: ::.: .. :..::. ..:....: . ... : : : . :: .. .
CCDS55 ICKIRPPADWQPPFAVEVDNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSL-K
50 60 70 80 90 100
650 660 670 680 690 700
pF1KE0 LPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQY
.: . ::: . . : ..: : :... :.. : . . .:
CCDS55 IPNVERKILDLYSLSKQCNTHPFDNEVKD-KEYK--------PHSIPLRQSVQPSKFSSY
110 120 130 140 150
710 720 730 740 750
pF1KE0 LLSYDSLSPEEH---RRLEKEVLMEKEILEKRKGPLE---GHTEND-----HHKFHPLPR
:.:. . . .::. ..: . :: : .: :.: :
CCDS55 SRRAKRLQPDPEPTEEDIEKHPELKKLQIYG-PGPKMMGLGLMAKDKDKTVHKKVTCPPT
160 170 180 190 200 210
760 770 780 790 800
pF1KE0 FEPKNGLIHGVAPRNGFRSK---LKEVGQAQLKTGRRRLFAQEKEVV------KEEEEDK
:. : . . .. :. .. .. . . :: . . .:.::
CCDS55 VTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDK
220 230 240 250 260 270
810 820
pF1KE0 -----GVLNDFH-------------------KCIYK---------G-----RSVSLTTFY
: ...: ::: : . :: .:
CCDS55 LLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFG
280 290 300 310 320 330
830 840 850 860 870 880
pF1KE0 RTARNIMSMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPVGKS
. : .. : :. . .:.: .:.:.:::: . :.:. : . .. ::::::..:
CCDS55 EMADSFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNS
340 350 360 370 380 390
890 900 910 920 930
pF1KE0 E----P----FSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSRDQN
. : .. ::::.:.: :.: :..: . :. .::: .:::::. :: . ..
CCDS55 KQNLSPEEKEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCW-HIED
400 410 420 430 440 450
940 950 960 970 980 990
pF1KE0 HLPY-IDYLHTGADCIWYCIPAEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISPEVL
: : :.::: : :: .:. ..::.:.. : .. : : . . ....:..:
CCDS55 HWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDL-LHQLVTLMNPNTL
460 470 480 490 500
1000 1010 1020 1030 1040 1050
pF1KE0 CKEGIKVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRR
..:. : :: : .:.::. :: .. : ::. .:.:.: :..: : . ....:
CCDS55 MSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRL
510 520 530 540 550 560
1060 1070 1080 1090 1100 1110
pF1KE0 HIAKPFSMEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARY
. :: :.:. ..: . . .... . .. ... : : :. :.: :. . :
CCDS55 RRYCVFSHEELICKMAAFPETLDLNLAVAVHKEMFIMVQE-ERRLRKALLEKGVTEAER-
570 580 590 600 610 620
1120 1130 1140 1150 1160
pF1KE0 GSHDGSSTVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECALRHV
. . : .::.: :. :.:: .. . . . :: :.
CCDS55 ----------------EAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----SHI
630 640 650 660
1170 1180 1190 1200 1210 1220
pF1KE0 EKQKSCRGLK--LMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVD
. .: . . : ::: ... ......
CCDS55 NDLCKCSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEEL
670 680 690 700 710 720
>>CCDS14794.1 KDM5D gene_id:8284|Hs108|chrY (1539 aa)
initn: 510 init1: 174 opt: 403 Z-score: 319.6 bits: 71.6 E(32554): 1.8e-11
Smith-Waterman score: 645; 25.0% identity (51.2% similar) in 772 aa overlap (556-1196:13-753)
530 540 550 560 570 580
pF1KE0 STSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFG
: ::..:: ::.::: :: ..: .:: :
CCDS14 MEPGCDEFLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSG
10 20 30 40
590 600 610 620 630 640
pF1KE0 MCRVIPPPDWRPECKLN-DEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDE
.:.. :: ::.: .. :..::. ..:....: . ... : : : . :: .. .
CCDS14 ICKIRPPADWQPPFAVEVDNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSSL-K
50 60 70 80 90 100
650 660 670 680 690 700
pF1KE0 LPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQY
.: . ::: . ... : ::.. . ..: ..:. :. : ... . :. : .
CCDS14 IPNVERKILDLYSLSKIVIEEGGYEAICKDRRWARVAQRLHYP-PGKNIGSLLRSHYERI
110 120 130 140 150 160
710 720 730
pF1KE0 LLSYDSLS-----------PEEHRRLEKE-----VLMEKEILE----------KRKGPLE
. :. .. : ... .:: . ... . :: :
CCDS14 IYPYEMFQSGANHVQCNTHPFDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDP
170 180 190 200 210 220
740 750 760 770 780
pF1KE0 GHTENDHHKFHPLPRFEPKNGLIHGVAPRN---GFRSKLKE--------------VGQAQ
::.: .: :: : :. :.: .:. :. .: :. : . :
CCDS14 EPTEEDIEK-HP----ELKKLQIYGPGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQ
230 240 250 260 270
790 800
pF1KE0 LKTGR--RRLFAQE-------KEVV---------------------KEEEEDK-----GV
: :. :. : .. . .:.:: :
CCDS14 SGGGNVSSTLLKQHLSLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDGC
280 290 300 310 320 330
810 820 830
pF1KE0 LNDFH-------------------KCIYK---------G-----RSVSLTTFYRTARNIM
...: ::: : . :: .: . : ..
CCDS14 DDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFGEMADSFK
340 350 360 370 380 390
840 850 860 870 880
pF1KE0 SMCFSK--EPAPAE-IEQEYWRLVEEKDCHVAVHCGK-VDTNTHGSGFPVGKSE----P-
: :. . .:.: .:.:.:::: . :.:. : . .. ::::::..:. :
CCDS14 SDYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVSNSKQNLSPE
400 410 420 430 440 450
890 900 910 920 930
pF1KE0 ---FSRHGWNLTVLPNNTGSILRHLGA-VPGVTIPWLNIGMVFSTSCWSRDQNHLPY-ID
.. ::::.:.: :.: :..: . :. .::: .:::::. :: . ..: : :.
CCDS14 EKEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCW-HIEDHWSYSIN
460 470 480 490 500 510
940 950 960 970 980 990
pF1KE0 YLHTGADCIWYCIPAEEENKLEDVVHTLLQA--NGTPGLQMLESNVMISPEVLCKEGIKV
::: : :: .:. ..::.:.. : .. : : . . ....:..: ..:. :
CCDS14 YLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDL-LHQLVTLMNPNTLMSHGVPV
520 530 540 550 560 570
1000 1010 1020 1030 1040 1050
pF1KE0 HRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFS
:: : .:.::. :: .. : ::. .:.:.: :..: : . ....: . ::
CCDS14 VRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFS
580 590 600 610 620 630
1060 1070 1080 1090 1100 1110
pF1KE0 MEKLLYQIAQAEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARYGSHDGSS
:.:. ..: . . .... . .. ... : : :. :.: :. . :
CCDS14 HEELICKMAAFPETLDLNLAVAVHKEMFIMVQE-ERRLRKALLEKGVTEAER--------
640 650 660 670 680
1120 1130 1140 1150 1160 1170
pF1KE0 TVADGKKKPRKWLQLETSERRCQICQHLCYLS-MVVQENENVVFCLECALRHVEKQKSCR
. . : .::.: :. :.:: .. . . . :: :.. .:
CCDS14 ---------EAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCL----SHINDLCKCS
690 700 710 720 730
1180 1190 1200 1210 1220 1230
pF1KE0 GLK--LMYRYDEEQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLS
. . : ::: ... ......
CCDS14 SSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVRVALEVEDGRKRSFEELRALESEA
740 750 760 770 780 790
1246 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:10:57 2016 done: Sun Nov 6 20:10:58 2016
Total Scan time: 5.100 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]