Result of FASTA (omim) for
pFN21AE0761
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0761, 337 aa
1>>>pF1KE0761 337 - 337 aa - 337 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3340+/-0.000359; mu= 7.2710+/- 0.022
mean_var=206.6411+/-43.379, 0's: 0 Z-trim(120.3): 175 B-trim: 742 in 1/56
Lambda= 0.089221
statistics sampled from 34935 (35306) to 34935 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.414), width: 16
Scan time: 9.060
The best scores are: opt bits E(85289)
NP_001123484 (OMIM: 606553) Na(+)/H(+) exchange re ( 337) 2305 309.2 8.3e-84
NP_004776 (OMIM: 606553) Na(+)/H(+) exchange regul ( 326) 1949 263.3 5.1e-70
XP_016879384 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 281) 1816 246.1 6.5e-65
NP_001239002 (OMIM: 606553) Na(+)/H(+) exchange re ( 226) 1362 187.6 2.2e-47
NP_001239004 (OMIM: 606553) Na(+)/H(+) exchange re ( 224) 1354 186.5 4.5e-47
XP_006721044 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 202) 1352 186.2 5e-47
XP_005255759 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 342) 1022 144.0 4.3e-34
NP_001239005 (OMIM: 606553) Na(+)/H(+) exchange re ( 215) 1006 141.7 1.3e-33
XP_016879383 (OMIM: 606553) PREDICTED: Na(+)/H(+) ( 372) 1001 141.4 3e-33
NP_004243 (OMIM: 604990,612287) Na(+)/H(+) exchang ( 358) 999 141.1 3.5e-33
NP_079067 (OMIM: 607146) Na(+)/H(+) exchange regul ( 491) 345 57.1 9.4e-08
NP_001161940 (OMIM: 607146) Na(+)/H(+) exchange re ( 505) 345 57.1 9.5e-08
XP_011541307 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 506) 345 57.1 9.6e-08
XP_016873823 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 557) 345 57.1 1e-07
XP_011541304 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 345 57.1 1e-07
XP_011541302 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 345 57.1 1e-07
XP_011541303 (OMIM: 607146) PREDICTED: Na(+)/H(+) ( 571) 345 57.1 1e-07
XP_016856956 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 312) 281 48.6 2.1e-05
XP_011507920 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 508) 284 49.2 2.2e-05
XP_011507918 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 512) 284 49.2 2.2e-05
XP_016856953 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 519) 284 49.2 2.2e-05
NP_001188254 (OMIM: 603831) Na(+)/H(+) exchange re ( 519) 284 49.2 2.2e-05
NP_002605 (OMIM: 603831) Na(+)/H(+) exchange regul ( 519) 284 49.2 2.2e-05
NP_001188255 (OMIM: 603831) Na(+)/H(+) exchange re ( 408) 282 48.9 2.3e-05
XP_016856955 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 277 48.2 3.6e-05
XP_011507921 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 277 48.2 3.6e-05
XP_016856954 (OMIM: 603831) PREDICTED: Na(+)/H(+) ( 409) 277 48.2 3.6e-05
XP_016862996 (OMIM: 602625) PREDICTED: membrane-as (1224) 272 48.1 0.00011
XP_016862990 (OMIM: 602625) PREDICTED: membrane-as (1452) 272 48.2 0.00013
XP_005265623 (OMIM: 602625) PREDICTED: membrane-as (1479) 272 48.2 0.00013
XP_005265622 (OMIM: 602625) PREDICTED: membrane-as (1481) 272 48.2 0.00013
XP_016862995 (OMIM: 602625) PREDICTED: membrane-as (1276) 267 47.5 0.00018
XP_016862989 (OMIM: 602625) PREDICTED: membrane-as (1455) 247 45.0 0.0012
XP_016862988 (OMIM: 602625) PREDICTED: membrane-as (1458) 247 45.0 0.0012
NP_001028229 (OMIM: 602625) membrane-associated gu (1462) 247 45.0 0.0012
XP_006713475 (OMIM: 602625) PREDICTED: membrane-as (1463) 247 45.0 0.0012
XP_006713474 (OMIM: 602625) PREDICTED: membrane-as (1465) 247 45.0 0.0012
XP_005265625 (OMIM: 602625) PREDICTED: membrane-as (1478) 247 45.0 0.0012
XP_006713473 (OMIM: 602625) PREDICTED: membrane-as (1479) 247 45.0 0.0012
XP_011532538 (OMIM: 602625) PREDICTED: membrane-as (1480) 247 45.0 0.0012
XP_016862987 (OMIM: 602625) PREDICTED: membrane-as (1490) 247 45.0 0.0012
XP_016862986 (OMIM: 602625) PREDICTED: membrane-as (1491) 247 45.0 0.0012
XP_005265621 (OMIM: 602625) PREDICTED: membrane-as (1491) 247 45.0 0.0012
XP_006713471 (OMIM: 602625) PREDICTED: membrane-as (1492) 247 45.0 0.0012
XP_005265620 (OMIM: 602625) PREDICTED: membrane-as (1492) 247 45.0 0.0012
XP_006713472 (OMIM: 602625) PREDICTED: membrane-as (1492) 247 45.0 0.0012
XP_006713470 (OMIM: 602625) PREDICTED: membrane-as (1493) 247 45.0 0.0012
NP_004733 (OMIM: 602625) membrane-associated guany (1256) 242 44.3 0.0017
NP_056335 (OMIM: 602625) membrane-associated guany (1287) 242 44.3 0.0017
XP_016862994 (OMIM: 602625) PREDICTED: membrane-as (1288) 242 44.3 0.0017
>>NP_001123484 (OMIM: 606553) Na(+)/H(+) exchange regula (337 aa)
initn: 2305 init1: 2305 opt: 2305 Z-score: 1625.6 bits: 309.2 E(85289): 8.3e-84
Smith-Waterman score: 2305; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KE0 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGL
250 260 270 280 290 300
310 320 330
pF1KE0 HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::::::::::::::::
NP_001 HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
310 320 330
>>NP_004776 (OMIM: 606553) Na(+)/H(+) exchange regulator (326 aa)
initn: 2353 init1: 1948 opt: 1949 Z-score: 1378.1 bits: 263.3 E(85289): 5.1e-70
Smith-Waterman score: 2186; 96.7% identity (96.7% similar) in 337 aa overlap (1-337:1-326)
10 20 30 40 50 60
pF1KE0 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 GVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 PKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 PGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGL
::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_004 VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTE-----------ESGL
250 260 270 280
310 320 330
pF1KE0 HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::::::::::::::::
NP_004 HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
290 300 310 320
>>XP_016879384 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (281 aa)
initn: 1816 init1: 1816 opt: 1816 Z-score: 1286.4 bits: 246.1 E(85289): 6.5e-65
Smith-Waterman score: 1816; 99.6% identity (100.0% similar) in 267 aa overlap (71-337:15-281)
50 60 70 80 90 100
pF1KE0 PGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQ
.:::::::::::::::::::::::::::::
XP_016 MDACAHRDRQTENLKVVQRIKAVEGQTRLLVVDQETDEELRRRQ
10 20 30 40
110 120 130 140 150 160
pF1KE0 LTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTCTEEMAQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQG
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE0 YGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKARE
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE0 DEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGS
170 180 190 200 210 220
290 300 310 320 330
pF1KE0 DKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
230 240 250 260 270 280
>>NP_001239002 (OMIM: 606553) Na(+)/H(+) exchange regula (226 aa)
initn: 1353 init1: 1353 opt: 1362 Z-score: 971.6 bits: 187.6 E(85289): 2.2e-47
Smith-Waterman score: 1362; 89.3% identity (91.0% similar) in 233 aa overlap (107-337:1-226)
80 90 100 110 120 130
pF1KE0 KAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRG--LPPAHDPWEPKPDWAHTGSHSSE
::. : :::. : : : .
NP_001 MARSGSATPPARAPGAP-P------RSPPQ
10 20
140 150 160 170 180 190
pF1KE0 AGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQD
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVQDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQD
30 40 50 60 70 80
200 210 220 230 240 250
pF1KE0 RLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPS
90 100 110 120 130 140
260 270 280 290 300 310
pF1KE0 PVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKAR
150 160 170 180 190 200
320 330
pF1KE0 AMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::
NP_001 AMRVNKRAPQMDWNRKREIFSNF
210 220
>>NP_001239004 (OMIM: 606553) Na(+)/H(+) exchange regula (224 aa)
initn: 1352 init1: 1352 opt: 1354 Z-score: 966.1 bits: 186.5 E(85289): 4.5e-47
Smith-Waterman score: 1367; 89.7% identity (91.0% similar) in 233 aa overlap (107-337:1-224)
80 90 100 110 120 130
pF1KE0 KAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRG--LPPAHDPWEPKPDWAHTGSHSSE
::. : :::. : : : :
NP_001 MARSGSATPPARAPGAP-P--------RSP
10 20
140 150 160 170 180 190
pF1KE0 AGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQD
. ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQRLDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQD
30 40 50 60 70 80
200 210 220 230 240 250
pF1KE0 RLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPS
90 100 110 120 130 140
260 270 280 290 300 310
pF1KE0 PVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKAR
150 160 170 180 190 200
320 330
pF1KE0 AMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::
NP_001 AMRVNKRAPQMDWNRKREIFSNF
210 220
>>XP_006721044 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (202 aa)
initn: 1352 init1: 1352 opt: 1352 Z-score: 965.3 bits: 186.2 E(85289): 5e-47
Smith-Waterman score: 1352; 99.5% identity (100.0% similar) in 200 aa overlap (138-337:3-202)
110 120 130 140 150 160
pF1KE0 AQRGLPPAHDPWEPKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHS
.:::::::::::::::::::::::::::::
XP_006 MPEDVSGPLRELRPRLCHLRKGPQGYGFNLHS
10 20 30
170 180 190 200 210 220
pF1KE0 DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE0 VDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDG
100 110 120 130 140 150
290 300 310 320 330
pF1KE0 SAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF
160 170 180 190 200
>>XP_005255759 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (342 aa)
initn: 1407 init1: 1002 opt: 1022 Z-score: 733.0 bits: 144.0 E(85289): 4.3e-34
Smith-Waterman score: 1022; 84.5% identity (87.7% similar) in 187 aa overlap (103-287:156-335)
80 90 100 110 120 130
pF1KE0 VQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRG--LPPAHDPWEPKPDWAHTGS
:. ::. : :::. : : :
XP_005 PQREVDKWGGSLGRPESSGHPGRTPATCCHCAAVMARSGSATPPARAPGAP-P------R
130 140 150 160 170
140 150 160 170 180 190
pF1KE0 HSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGL
. .::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPPQRLVQDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGL
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE0 RAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEG
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE0 PLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAK
:::::::::::::::::::::::::::::::::::.:
XP_005 PLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEEGPPSGVWD
300 310 320 330 340
320 330
pF1KE0 EKARAMRVNKRAPQMDWNRKREIFSNF
>>NP_001239005 (OMIM: 606553) Na(+)/H(+) exchange regula (215 aa)
initn: 1399 init1: 994 opt: 1006 Z-score: 724.2 bits: 141.7 E(85289): 1.3e-33
Smith-Waterman score: 1243; 84.5% identity (86.3% similar) in 233 aa overlap (107-337:1-215)
80 90 100 110 120 130
pF1KE0 KAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRG--LPPAHDPWEPKPDWAHTGSHSSE
::. : :::. : : : .
NP_001 MARSGSATPPARAPGAP-P------RSPPQ
10 20
140 150 160 170 180 190
pF1KE0 AGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQD
.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLVQDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGLRAQD
30 40 50 60 70 80
200 210 220 230 240 250
pF1KE0 RLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPS
90 100 110 120 130 140
260 270 280 290 300 310
pF1KE0 PVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKAR
::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_001 PVTNGTSPAQLNGGSACSSRSDLPGSDKDTE-----------ESGLHLSPTAAEAKEKAR
150 160 170 180 190
320 330
pF1KE0 AMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::
NP_001 AMRVNKRAPQMDWNRKREIFSNF
200 210
>>XP_016879383 (OMIM: 606553) PREDICTED: Na(+)/H(+) exch (372 aa)
initn: 1399 init1: 994 opt: 1001 Z-score: 718.0 bits: 141.4 E(85289): 3e-33
Smith-Waterman score: 1257; 84.0% identity (85.7% similar) in 237 aa overlap (103-337:156-372)
80 90 100 110 120 130
pF1KE0 VQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRG--LPPAHDPWEPKPDWAHTGS
:. ::. : :::. : : :
XP_016 PQREVDKWGGSLGRPESSGHPGRTPATCCHCAAVMARSGSATPPARAPGAP-P-------
130 140 150 160 170
140 150 160 170 180 190
pF1KE0 HSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGL
: . ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -RSPPQRLDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSGL
180 190 200 210 220 230
200 210 220 230 240 250
pF1KE0 RAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEG
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE0 PLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAK
::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_016 PLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTE-----------ESGLHLSPTAAEAK
300 310 320 330 340
320 330
pF1KE0 EKARAMRVNKRAPQMDWNRKREIFSNF
:::::::::::::::::::::::::::
XP_016 EKARAMRVNKRAPQMDWNRKREIFSNF
350 360 370
>>NP_004243 (OMIM: 604990,612287) Na(+)/H(+) exchange re (358 aa)
initn: 1083 init1: 966 opt: 999 Z-score: 716.8 bits: 141.1 E(85289): 3.5e-33
Smith-Waterman score: 1104; 52.1% identity (72.0% similar) in 361 aa overlap (2-337:6-358)
10 20 30 40 50
pF1KE0 MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRL
:: :: :::: : .: .:::::::::::. ::.:: :::::::: :.: :::::
NP_004 MSADAAAGAPL-PRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 VEVNGVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEM--AQRGLPP
::::: ::: :::.:::.::.:. . .:::::: ::::.:.. . ::. ::.. :
NP_004 VEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEA-PG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 AHDPWEPKPDWAHTGSHSSEAGKKDVSGP-LRELRPRLCHLRKGPQGYGFNLHSDKSRPG
.: : .. ... .: . : : : :::::::: ..:::.:::::::::::.::
NP_004 QAEP--PAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 QYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETD
:.:::::: ::: ::::::::..:::: .:: .:..::..:.: ::..::::: :::
NP_004 QFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETD
180 190 200 210 220 230
240 250 260 270
pF1KE0 EHFKRLRVTPTEEHVEGPLPSPVTNGT------------------SPAQLNGGSACSSR-
: ::. :: :..::..:::: : ::: :: . ..:. .:.
NP_004 EFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 ---SDLPGSDKDTEDGSAWKQDPFQESGLHLSPTAAEAKEKARAMRVNKRAPQMDWNRKR
.: : .. .: .:. ..::. : .. . : :::.:. : .::::::::..:
NP_004 LNSQDSPPKQDSTAPSSTSSSDPI----LDFNISLAMAKERAHQKRSSKRAPQMDWSKKN
300 310 320 330 340 350
pF1KE0 EIFSNF
:.:::.
NP_004 ELFSNL
337 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:40:05 2016 done: Sun Nov 6 10:40:06 2016
Total Scan time: 9.060 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]