Result of FASTA (omim) for
pFN21AE0732
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0732, 420 aa
1>>>pF1KE0732 420 - 420 aa - 420 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8664+/-0.000354; mu= 14.1823+/- 0.022
mean_var=235.8652+/-53.232, 0's: 0 Z-trim(121.1): 173 B-trim: 1851 in 1/52
Lambda= 0.083511
statistics sampled from 36926 (37138) to 36926 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.435), width: 16
Scan time: 5.530
The best scores are: opt bits E(85289)
NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420) 2873 358.9 1.4e-98
NP_001193929 (OMIM: 607137,609115) heterogeneous n ( 363) 2305 290.4 5e-78
NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 1263 164.8 3e-40
NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332) 1205 157.8 3.8e-38
NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 1205 157.8 3.9e-38
NP_001003810 (OMIM: 601324) heterogeneous nuclear ( 287) 1046 138.5 2e-32
NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 1016 134.9 2.5e-31
NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 988 131.6 2.7e-30
NP_001317179 (OMIM: 605372) heterogeneous nuclear ( 331) 669 93.2 1e-18
NP_001317180 (OMIM: 605372) heterogeneous nuclear ( 331) 669 93.2 1e-18
NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353) 669 93.2 1.1e-18
XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353) 669 93.2 1.1e-18
XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341) 667 93.0 1.2e-18
XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341) 667 93.0 1.2e-18
NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341) 667 93.0 1.2e-18
NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378) 661 92.3 2.2e-18
NP_001317178 (OMIM: 605372) heterogeneous nuclear ( 378) 661 92.3 2.2e-18
NP_001317176 (OMIM: 605372) heterogeneous nuclear ( 356) 659 92.1 2.5e-18
NP_001317177 (OMIM: 605372) heterogeneous nuclear ( 356) 659 92.1 2.5e-18
NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372) 659 92.1 2.6e-18
XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372) 659 92.1 2.6e-18
NP_002127 (OMIM: 164017,615424,615426) heterogeneo ( 320) 648 90.7 5.9e-18
XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 639 89.6 1.3e-17
XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 639 89.6 1.3e-17
NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 623 87.7 4.8e-17
XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295) 622 87.5 4.9e-17
NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255) 620 87.1 5.3e-17
XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295) 621 87.4 5.3e-17
NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 594 84.2 5.4e-16
NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 588 83.4 8.6e-16
NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251) 581 82.4 1.4e-15
XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332) 550 78.9 2.1e-14
XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 550 78.9 2.2e-14
XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351) 550 78.9 2.2e-14
NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362) 550 78.9 2.3e-14
XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362) 550 78.9 2.3e-14
XP_016856354 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 410 62.1 2.9e-09
XP_016856355 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 410 62.1 2.9e-09
XP_016856352 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 410 62.1 2.9e-09
XP_016856353 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 410 62.1 2.9e-09
XP_016856357 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 410 62.1 2.9e-09
NP_031401 (OMIM: 605078,612069) TAR DNA-binding pr ( 414) 410 62.1 2.9e-09
XP_016856356 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 410 62.1 2.9e-09
XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315) 358 55.7 1.9e-07
XP_016879638 (OMIM: 607897) PREDICTED: RNA-binding ( 259) 307 49.4 1.2e-05
XP_011522588 (OMIM: 607897) PREDICTED: RNA-binding ( 242) 305 49.2 1.4e-05
XP_005259588 (OMIM: 607430) PREDICTED: DAZ-associa ( 406) 303 49.2 2.2e-05
NP_733829 (OMIM: 607430) DAZ-associated protein 1 ( 378) 301 49.0 2.5e-05
XP_016882070 (OMIM: 607430) PREDICTED: DAZ-associa ( 406) 301 49.0 2.6e-05
NP_061832 (OMIM: 607430) DAZ-associated protein 1 ( 407) 301 49.0 2.6e-05
>>NP_112740 (OMIM: 607137,609115) heterogeneous nuclear (420 aa)
initn: 2873 init1: 2873 opt: 2873 Z-score: 1890.9 bits: 358.9 E(85289): 1.4e-98
Smith-Waterman score: 2873; 100.0% identity (100.0% similar) in 420 aa overlap (1-420:1-420)
10 20 30 40 50 60
pF1KE0 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 EDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 TDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 SPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 GKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 YNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 YNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
370 380 390 400 410 420
>>NP_001193929 (OMIM: 607137,609115) heterogeneous nucle (363 aa)
initn: 2627 init1: 2294 opt: 2305 Z-score: 1521.8 bits: 290.4 E(85289): 5e-78
Smith-Waterman score: 2319; 86.4% identity (86.4% similar) in 420 aa overlap (1-420:1-363)
10 20 30 40 50 60
pF1KE0 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAQQPSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 EDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 SPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 GKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGN
::::::::::::::::::::::::::::::::::::::::::
NP_001 GKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQ------------------
310 320 330 340
370 380 390 400 410 420
pF1KE0 YNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
:::::::::::::::::::::
NP_001 ---------------------------------------QSTYGKASRGGGNHQNNYQPY
350 360
>>NP_112737 (OMIM: 601324) heterogeneous nuclear ribonuc (336 aa)
initn: 1480 init1: 1022 opt: 1263 Z-score: 843.6 bits: 164.8 E(85289): 3e-40
Smith-Waterman score: 1360; 69.8% identity (88.9% similar) in 288 aa overlap (133-420:63-336)
110 120 130 140 150 160
pF1KE0 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKK
.::.::.::::..:.::::::::::::.::
NP_112 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR
:: .:.:.::::::::.: ::.:::::::::::::.. :::::.. :::::.::.:::::
NP_112 DLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE0 AKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYT
:::.: ::: ::.::::::::: ::.:.::::.:::.:.::::::.:::.::::::::.
NP_112 AKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFK
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE0 DEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQ
.::::::..:..::..: .:::::::. :: : ::::: :.::. :: : .:::: :
NP_112 EEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWGSRGGFAG-R--ARGRGGGP
220 230 240 250 260
350 360 370 380 390 400
pF1KE0 GQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQST
.::::::..::..:::::: .:.. :.:.::::::::::: . :::: :::.:::
NP_112 SQNWNQGYSNYWNQGYGNY--GYNS-QGYGGYGGYDYTGYN-NYYGYG----DYSNQQSG
270 280 290 300 310
410 420
pF1KE0 YGKASRGGGNHQNNYQPY
:::.:: :: :::.:.::
NP_112 YGKVSRRGG-HQNSYKPY
320 330
>>NP_112556 (OMIM: 602688) heterogeneous nuclear ribonuc (332 aa)
initn: 1188 init1: 557 opt: 1205 Z-score: 805.9 bits: 157.8 E(85289): 3.8e-38
Smith-Waterman score: 1287; 66.2% identity (85.2% similar) in 290 aa overlap (133-420:55-332)
110 120 130 140 150 160
pF1KE0 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKK
:::..::::::..: ::::.::::::::::
NP_112 EGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKK
30 40 50 60 70 80
170 180 190 200 210 220
pF1KE0 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR
:: .:...:::::::::: :: :::::::::.::::::::.:::. :::.:::..::::.
NP_112 DLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKK
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE0 AKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYT
: :.: :.: ::.:::::.:...::.:.:::: ::::: :::::: : :.:::: :::.
NP_112 AMAMK-KDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFK
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE0 DEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAA-GGRG-GTRGRGR
.::::::.::...: ....::::::::::::: :::: .:::: :.:: : : :
NP_112 EEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVY-QQQQYGSGGRGNRNRGNRGSGGGGGGG
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE0 GQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQ
::.:.::::..::..:::: :...:: :::::::. :.: :::: :: ::: .
NP_112 GQSQSWNQGYGNYWNQGYG-YQQGYG-----PGYGGYDYSPYGY--YGYGPGY-DYSQGS
270 280 290 300 310
410 420
pF1KE0 STYGKASRGGGNHQNNYQPY
..:::..: :: :::::.::
NP_112 TNYGKSQRRGG-HQNNYKPY
320 330
>>NP_112738 (OMIM: 601324) heterogeneous nuclear ribonuc (355 aa)
initn: 1420 init1: 962 opt: 1205 Z-score: 805.6 bits: 157.8 E(85289): 3.9e-38
Smith-Waterman score: 1312; 65.5% identity (83.4% similar) in 307 aa overlap (133-420:63-355)
110 120 130 140
pF1KE0 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG--------------
.::.::.::::..:.:
NP_112 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 -----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVD
:::::::::::.:::: .:.:.::::::::.: ::.:::::::::::::.. :::
NP_112 QREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 KVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIE
::.. :::::.::.::::::::.: ::: ::.::::::::: ::.:.::::.:::.:.::
NP_112 KVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 LPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKG
::::.:::.::::::::. .::::::..:..::..: .:::::::. :: : ::::: :
NP_112 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQY--QQQQQWG
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE0 GRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYN
.::. :: : .:::: : .::::::..::..:::::: .:.. :.:.:::::::::::
NP_112 SRGGFAG-R--ARGRGGGPSQNWNQGYSNYWNQGYGNY--GYNS-QGYGGYGGYDYTGYN
280 290 300 310 320
390 400 410 420
pF1KE0 YGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
. :::: :::.::: :::.:: :: :::.:.::
NP_112 -NYYGYG----DYSNQQSGYGKVSRRGG-HQNSYKPY
330 340 350
>>NP_001003810 (OMIM: 601324) heterogeneous nuclear ribo (287 aa)
initn: 1168 init1: 995 opt: 1046 Z-score: 703.0 bits: 138.5 E(85289): 2e-32
Smith-Waterman score: 1055; 65.8% identity (87.0% similar) in 231 aa overlap (133-363:63-283)
110 120 130 140 150 160
pF1KE0 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKK
.::.::.::::..:.::::::::::::.::
NP_001 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE0 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR
:: .:.:.::::::::.: ::.:::::::::::::.. :::::.. :::::.::.:::::
NP_001 DLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE0 AKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYT
:::.: ::: ::.::::::::: ::.:.::::.:::.:.::::::.:::.::::::::.
NP_001 AKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFK
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE0 DEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQ
.::::::..:..::..: .:::::::. :: :.:::: :.::: ::.::.
NP_001 EEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQW---------GSRGGFAGRARGR
220 230 240 250 260
350 360 370 380 390 400
pF1KE0 GQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQST
: . ..:... .: :. ::
NP_001 GGDQQSGYGKVSRRG-GHQNSYKPY
270 280
>>NP_004490 (OMIM: 602688) heterogeneous nuclear ribonuc (285 aa)
initn: 986 init1: 513 opt: 1016 Z-score: 683.5 bits: 134.9 E(85289): 2.5e-31
Smith-Waterman score: 1016; 65.0% identity (83.8% similar) in 234 aa overlap (133-365:55-282)
110 120 130 140 150 160
pF1KE0 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKK
:::..::::::..: ::::.::::::::::
NP_004 EGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKK
30 40 50 60 70 80
170 180 190 200 210 220
pF1KE0 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR
:: .:...:::::::::: :: :::::::::.::::::::.:::. :::.:::..::::.
NP_004 DLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKK
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE0 AKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYT
: :.: :.: ::.:::::.:...::.:.:::: ::::: :::::: : :.:::: :::.
NP_004 AMAMK-KDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFK
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE0 DEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQ
.::::::.::...: ....::::::::::::: :::: .:::: : :. : : :
NP_004 EEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVY-QQQQYGSGGRGNRNRGNRGSGGGGGGG
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE0 GQNWNQGFNNY-YDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQS
:: : .:: .: :.... :
NP_004 GQ----GSTNYGKSQRRGGHQNNYKPY
270 280
>>NP_002129 (OMIM: 601324) heterogeneous nuclear ribonuc (306 aa)
initn: 1107 init1: 934 opt: 988 Z-score: 665.0 bits: 131.6 E(85289): 2.7e-30
Smith-Waterman score: 1007; 60.8% identity (80.4% similar) in 250 aa overlap (133-363:63-302)
110 120 130 140
pF1KE0 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDG--------------
.::.::.::::..:.:
NP_002 ATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 -----KMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVD
:::::::::::.:::: .:.:.::::::::.: ::.:::::::::::::.. :::
NP_002 QREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVD
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 KVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIE
::.. :::::.::.::::::::.: ::: ::.::::::::: ::.:.::::.:::.:.::
NP_002 KVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIE
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 LPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKG
::::.:::.::::::::. .::::::..:..::..: .:::::::. :: :.::::
NP_002 LPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQW---
220 230 240 250 260
330 340 350 360 370 380
pF1KE0 GRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYN
:.::: ::.::.: . ..:... .: :. ::
NP_002 ------GSRGGFAGRARGRGGDQQSGYGKVSRRG-GHQNSYKPY
270 280 290 300
390 400 410 420
pF1KE0 YGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
>>NP_001317179 (OMIM: 605372) heterogeneous nuclear ribo (331 aa)
initn: 563 init1: 320 opt: 669 Z-score: 456.9 bits: 93.2 E(85289): 1e-18
Smith-Waterman score: 669; 38.2% identity (67.8% similar) in 301 aa overlap (135-420:22-313)
110 120 130 140 150 160
pF1KE0 TRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDL
: . . :. .. :.::::::..:. .:
NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSL
10 20 30 40 50
170 180 190 200 210 220
pF1KE0 TEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAK
:.. ..: ..::.. :: : :::::::: .. . :: .. . ::.::....::::
NP_001 REHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAV
60 70 80 90 100 110
230 240 250 260 270
pF1KE0 ALKGKEPP------KKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCF
. . . : ::.::::.. :: : ....:: .:.::.::. : .....::: :
NP_001 SREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAF
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE0 ITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAG---GRGGT
.:. :.. : :.. ..:: :.. .::.: : :. ... .:. :::...: ::::.
NP_001 VTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQR--GRGGGSGNFMGRGGN
180 190 200 210 220
340 350 360 370 380 390
pF1KE0 RGRGRGQ-GQNWNQGFNNYYDQGYGNYNSAYGG-DQNYSGYGGYDYTGYNYGNYGYGQGY
: : :. :.. : : . : : :. ..::: : .:.:.:: : :::: : .:
NP_001 FGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGG-D------GNYGGGGNY
230 240 250 260 270 280
400 410 420
pF1KE0 AD---YSGQQ-STYGKASRGGGNHQNNYQPY
: ::::: :.:: . :. . ... .::
NP_001 NDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
290 300 310 320 330
>>NP_001317180 (OMIM: 605372) heterogeneous nuclear ribo (331 aa)
initn: 563 init1: 320 opt: 669 Z-score: 456.9 bits: 93.2 E(85289): 1e-18
Smith-Waterman score: 669; 38.2% identity (67.8% similar) in 301 aa overlap (135-420:22-313)
110 120 130 140 150 160
pF1KE0 TRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDL
: . . :. .. :.::::::..:. .:
NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSL
10 20 30 40 50
170 180 190 200 210 220
pF1KE0 TEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAK
:.. ..: ..::.. :: : :::::::: .. . :: .. . ::.::....::::
NP_001 REHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAV
60 70 80 90 100 110
230 240 250 260 270
pF1KE0 ALKGKEPP------KKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCF
. . . : ::.::::.. :: : ....:: .:.::.::. : .....::: :
NP_001 SREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAF
120 130 140 150 160 170
280 290 300 310 320 330
pF1KE0 ITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAG---GRGGT
.:. :.. : :.. ..:: :.. .::.: : :. ... .:. :::...: ::::.
NP_001 VTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQR--GRGGGSGNFMGRGGN
180 190 200 210 220
340 350 360 370 380 390
pF1KE0 RGRGRGQ-GQNWNQGFNNYYDQGYGNYNSAYGG-DQNYSGYGGYDYTGYNYGNYGYGQGY
: : :. :.. : : . : : :. ..::: : .:.:.:: : :::: : .:
NP_001 FGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGG-D------GNYGGGGNY
230 240 250 260 270 280
400 410 420
pF1KE0 AD---YSGQQ-STYGKASRGGGNHQNNYQPY
: ::::: :.:: . :. . ... .::
NP_001 NDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSRRF
290 300 310 320 330
420 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:25:05 2016 done: Tue Nov 8 01:25:06 2016
Total Scan time: 5.530 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]