Result of FASTA (omim) for
pFN21AE0658
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0658, 389 aa
1>>>pF1KE0658 389 - 389 aa - 389 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6447+/-0.000316; mu= 21.0668+/- 0.020
mean_var=101.9287+/-25.814, 0's: 0 Z-trim(116.0): 490 B-trim: 2666 in 2/48
Lambda= 0.127036
statistics sampled from 26094 (26845) to 26094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.315), width: 16
Scan time: 7.950
The best scores are: opt bits E(85289)
XP_011532064 (OMIM: 167055) PREDICTED: oxytocin re ( 389) 2580 483.6 3.4e-136
NP_000907 (OMIM: 167055) oxytocin receptor [Homo s ( 389) 2580 483.6 3.4e-136
NP_000697 (OMIM: 600821) vasopressin V1a receptor ( 418) 1249 239.7 9.5e-63
XP_006724891 (OMIM: 300538,300539,304800) PREDICTE ( 371) 915 178.4 2.4e-44
NP_000045 (OMIM: 300538,300539,304800) vasopressin ( 371) 915 178.4 2.4e-44
NP_000698 (OMIM: 600264) vasopressin V1b receptor ( 424) 812 159.6 1.2e-38
NP_001139623 (OMIM: 300538,300539,304800) vasopres ( 309) 756 149.2 1.3e-35
NP_997055 (OMIM: 608584,608595) neuropeptide S rec ( 371) 443 91.9 2.6e-18
NP_997056 (OMIM: 608584,608595) neuropeptide S rec ( 377) 443 91.9 2.6e-18
NP_001287864 (OMIM: 608584,608595) neuropeptide S ( 390) 443 92.0 2.7e-18
NP_001287862 (OMIM: 608584,608595) neuropeptide S ( 366) 360 76.7 9.8e-14
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 312 68.0 4.6e-11
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328) 299 65.5 2.1e-10
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 300 65.9 2.5e-10
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 299 65.7 2.6e-10
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 293 64.4 4.9e-10
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 293 64.4 4.9e-10
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 293 64.5 5.2e-10
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 287 63.3 1.1e-09
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 287 63.4 1.1e-09
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 279 61.9 2.9e-09
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 279 61.9 2.9e-09
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 279 61.9 2.9e-09
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 279 61.9 2.9e-09
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 279 61.9 3e-09
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 279 61.9 3e-09
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 279 61.9 3e-09
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 279 61.9 3e-09
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 278 61.8 3.5e-09
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 272 60.6 7.2e-09
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 272 60.6 7.3e-09
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 271 60.4 8e-09
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 271 60.4 8e-09
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 270 60.3 9.4e-09
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 268 59.9 1.3e-08
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 268 59.9 1.3e-08
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 268 59.9 1.3e-08
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 268 59.9 1.3e-08
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 268 59.9 1.3e-08
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 268 59.9 1.3e-08
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 268 59.9 1.3e-08
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 267 59.7 1.3e-08
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 267 59.8 1.5e-08
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 267 59.8 1.5e-08
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 267 59.8 1.5e-08
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 266 59.5 1.6e-08
XP_016866823 (OMIM: 606915) PREDICTED: probable G- ( 419) 266 59.6 1.6e-08
XP_011534456 (OMIM: 606915) PREDICTED: probable G- ( 419) 266 59.6 1.6e-08
XP_011534455 (OMIM: 606915) PREDICTED: probable G- ( 419) 266 59.6 1.6e-08
XP_006715633 (OMIM: 606915) PREDICTED: probable G- ( 419) 266 59.6 1.6e-08
>>XP_011532064 (OMIM: 167055) PREDICTED: oxytocin recept (389 aa)
initn: 2580 init1: 2580 opt: 2580 Z-score: 2566.2 bits: 483.6 E(85289): 3.4e-136
Smith-Waterman score: 2580; 100.0% identity (100.0% similar) in 389 aa overlap (1-389:1-389)
10 20 30 40 50 60
pF1KE0 MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
310 320 330 340 350 360
370 380
pF1KE0 SASKKSNSSSFVLSHRSSSQRSCSQPSTA
:::::::::::::::::::::::::::::
XP_011 SASKKSNSSSFVLSHRSSSQRSCSQPSTA
370 380
>>NP_000907 (OMIM: 167055) oxytocin receptor [Homo sapie (389 aa)
initn: 2580 init1: 2580 opt: 2580 Z-score: 2566.2 bits: 483.6 E(85289): 3.4e-136
Smith-Waterman score: 2580; 100.0% identity (100.0% similar) in 389 aa overlap (1-389:1-389)
10 20 30 40 50 60
pF1KE0 MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
310 320 330 340 350 360
370 380
pF1KE0 SASKKSNSSSFVLSHRSSSQRSCSQPSTA
:::::::::::::::::::::::::::::
NP_000 SASKKSNSSSFVLSHRSSSQRSCSQPSTA
370 380
>>NP_000697 (OMIM: 600821) vasopressin V1a receptor [Hom (418 aa)
initn: 1060 init1: 504 opt: 1249 Z-score: 1247.5 bits: 239.7 E(85289): 9.5e-63
Smith-Waterman score: 1249; 49.7% identity (75.5% similar) in 380 aa overlap (13-382:25-398)
10 20 30 40
pF1KE0 MEGALAANWSAEAANAS-AAPPGAEGNRTAGPPR--RNEALARVEVAV
:.:.: : .::: :::: ::: ::..:.::
NP_000 MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGN---GPPRDVRNEELAKLEIAV
10 20 30 40 50
50 60 70 80 90 100
pF1KE0 LCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRF
: . . .:. ::. :::::. : .: ::. .:..:::.:::.:: ::::::. ::::.::
NP_000 LAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRF
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 YGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLG
::: :::.::.::: :::::.:.:..:. :: .:.:.::..:.. : .:: . :.:.
NP_000 RGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 CLVASAPQVHIFSLREVAD--GVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYG
.: :.:: .::. :: . . ::::.:::::: .::.::.: .....::..:..:::
NP_000 SFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 LISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIV
.: ..:: :.: :::. . : ....: . : . ::::: ::.::::::::::.::
NP_000 FICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIV
240 250 260 270 280 290
290 300 310 320 330
pF1KE0 LAFIVCWTPFFFVQMWSVWDANA---PKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFH
:.::::.:::..::::::: . .: .. :. ::.::::::::::::.:.:::..
NP_000 TAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQ
300 310 320 330 340 350
340 350 360 370 380
pF1KE0 ELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
. :: : ::. : . : :... .: ..:: .. .
NP_000 DCVQSFPCCQNMKEKFNKEDTDSMSRRQ---TFYSNNRSPTNSTGMWKDSPKSSKSIKFI
360 370 380 390 400 410
NP_000 PVST
>>XP_006724891 (OMIM: 300538,300539,304800) PREDICTED: v (371 aa)
initn: 807 init1: 331 opt: 915 Z-score: 917.2 bits: 178.4 E(85289): 2.4e-44
Smith-Waterman score: 923; 42.3% identity (67.0% similar) in 388 aa overlap (13-379:4-371)
10 20 30 40 50
pF1KE0 MEGALAANWSAEAANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLA
:...::.: :. .: . : :. :::.:.:.: .... .
XP_006 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSGNACVLLAL-RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLL
.:. :: :: : :. : . . :. :: .:::.::.::::::: : : :: ::: :
XP_006 ALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDAL
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 CRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRT----DRLAVLATWLGCLVA
:: :::::.:::.::.:..: :.::: :::.:. . :. . .: ::..: :.
XP_006 CRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNR-PVLVAWAFSLLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 SAPQVHIFSLREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISF
: ::. ::. :.: ..:: :::: : .::: ..:.:::.: :...:.. .::: ::
XP_006 SLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 KIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVL
.: .: . . .: : ::: :..: .: : .::.::..::.
XP_006 EIHASL-----VPGPSERP-------GGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVV
240 250 260 270
290 300 310 320 330 340
pF1KE0 AFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQ
....::.:::.::.:..:: .:: :.. :...::::::::: ::::: :.. . :: .
XP_006 VYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSEL-R
280 290 300 310 320 330
350 360 370 380
pF1KE0 RFLCCSASYLKGRR---LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
.:::. .:: :: . : . ::: :.. .::
XP_006 SLLCCA----RGRTPPSLGPQDESCTTASSS--LAKDTSS
340 350 360 370
>>NP_000045 (OMIM: 300538,300539,304800) vasopressin V2 (371 aa)
initn: 807 init1: 331 opt: 915 Z-score: 917.2 bits: 178.4 E(85289): 2.4e-44
Smith-Waterman score: 923; 42.3% identity (67.0% similar) in 388 aa overlap (13-379:4-371)
10 20 30 40 50
pF1KE0 MEGALAANWSAEAANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLA
:...::.: :. .: . : :. :::.:.:.: .... .
NP_000 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSGNACVLLAL-RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLL
.:. :: :: : :. : . . :. :: .:::.::.::::::: : : :: ::: :
NP_000 ALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDAL
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 CRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRT----DRLAVLATWLGCLVA
:: :::::.:::.::.:..: :.::: :::.:. . :. . .: ::..: :.
NP_000 CRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNR-PVLVAWAFSLLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 SAPQVHIFSLREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISF
: ::. ::. :.: ..:: :::: : .::: ..:.:::.: :...:.. .::: ::
NP_000 SLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 KIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVL
.: .: . . .: : ::: :..: .: : .::.::..::.
NP_000 EIHASL-----VPGPSERP-------GGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVV
240 250 260 270
290 300 310 320 330 340
pF1KE0 AFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQ
....::.:::.::.:..:: .:: :.. :...::::::::: ::::: :.. . :: .
NP_000 VYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSEL-R
280 290 300 310 320 330
350 360 370 380
pF1KE0 RFLCCSASYLKGRR---LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
.:::. .:: :: . : . ::: :.. .::
NP_000 SLLCCA----RGRTPPSLGPQDESCTTASSS--LAKDTSS
340 350 360 370
>>NP_000698 (OMIM: 600264) vasopressin V1b receptor [Hom (424 aa)
initn: 1154 init1: 494 opt: 812 Z-score: 814.6 bits: 159.6 E(85289): 1.2e-38
Smith-Waterman score: 1224; 52.3% identity (75.5% similar) in 371 aa overlap (15-368:8-378)
10 20 30 40 50
pF1KE0 MEGALAANWSAEAANASAAPPGAEGNRTAGPPR--RNEALARVEVAVLCLILLLALSGNA
.:. .: :. . .: : :.: ::.::..:: .:.:: .::
NP_000 MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNL
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 CVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYL
:::.: .:.::. .:. ::...::.::.::::::::::::.:: ::::::: ::::
NP_000 AVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE0 QVVGMFASTYLLLLMSLDRCLAICQPLRSLRR--RTDRLAVLATWLGCLVASAPQVHIFS
::..::::::.:: :.::: ::.:.:::::.. .. : . : :: . : ::: :::
NP_000 QVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 LREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLK
:::: ..::.:::: : ::::.::.:: :::....:: .:.:::.:: .: .::..:
NP_000 LREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVK
180 190 200 210 220 230
240 250 260 270 280
pF1KE0 TAAAAAA-------EAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVC
: : .. . : .. . : .::::.. ::.::::::::::.::::.:.:
NP_000 TQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIAC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE0 WTPFFFVQMWSVWDANAPKEAS---AFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRF
:.::: :::::::: ::: : : :: : :::..::::::::::: :..::. . ....
NP_000 WAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHL
300 310 320 330 340 350
350 360 370 380
pF1KE0 LCCSASYLKGRR-LGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
::.. . :: :.. : :.. ..
NP_000 ACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELA
360 370 380 390 400 410
>>NP_001139623 (OMIM: 300538,300539,304800) vasopressin (309 aa)
initn: 666 init1: 331 opt: 756 Z-score: 760.6 bits: 149.2 E(85289): 1.3e-35
Smith-Waterman score: 761; 42.2% identity (67.1% similar) in 313 aa overlap (13-307:4-303)
10 20 30 40 50
pF1KE0 MEGALAANWSAEAANASAAP-----PGAEGNRTAGPP--RRNEALARVEVAVLCLILLLA
:...::.: :. .: . : :. :::.:.:.: .... .
NP_001 MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAV
10 20 30 40 50
60 70 80 90 100 110
pF1KE0 LSGNACVLLAL-RTTRQKH-SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLL
.:. :: :: : :. : . . :. :: .:::.::.::::::: : : :: ::: :
NP_001 ALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDAL
60 70 80 90 100 110
120 130 140 150 160
pF1KE0 CRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRT----DRLAVLATWLGCLVA
:: :::::.:::.::.:..: :.::: :::.:. . :. . .: ::..: :.
NP_001 CRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNR-PVLVAWAFSLLL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 SAPQVHIFSLREV--ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISF
: ::. ::. :.: ..:: :::: : .::: ..:.:::.: :...:.. .::: ::
NP_001 SLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 KIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSV---KLISKAKIRTVKMTFIIVL
.: .: .: : . ::: :..: .: : .::.::..::.
NP_001 EIHASL-----------VP-GPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVV
240 250 260 270
290 300 310 320 330 340
pF1KE0 AFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQ
....::.:::.::.:..:: .:: :
NP_001 VYVLCWAPFFLVQLWAAWDPEAPLEGGCSRG
280 290 300
>>NP_997055 (OMIM: 608584,608595) neuropeptide S recepto (371 aa)
initn: 575 init1: 228 opt: 443 Z-score: 449.7 bits: 91.9 E(85289): 2.6e-18
Smith-Waterman score: 570; 32.0% identity (67.7% similar) in 300 aa overlap (42-336:52-337)
20 30 40 50 60 70
pF1KE0 EAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKH
.. .: ....... ::. ::.. :.:.
NP_997 SPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWR-RKKK
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE0 SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLL
::. ::. .:.:.: ... ..: .. : .: : .:::.::.:.::::: ..::::.:.
NP_997 SRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLV
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE0 LMSLDRCLAICQPLRSLR-RRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAV
.:.:: :: :.. :. .. :. .. .: .. : : . ::. : ...: .:::.
NP_997 SLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWAL
150 160 170 180 190 200
200 210 220 230 240
pF1KE0 FIQP--WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAA
. . : : :.: ... ::..:. ... ::.. :: .. :: .. .. .:
NP_997 WPDDSYWTP--YMTIVAFLVYFIPLTIISIMYGIVIRTIW--IKSKTYETVISNCSDGKL
210 220 230 240 250
250 260 270 280 290 300
pF1KE0 AGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD--ANAPK
.. .: :::::::...:...::.:::: ::.:.:. .. . .. .. .
NP_997 CSSYNR---------GLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQE
260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKS
. : .:.. : .::: :: :: .:.. .
NP_997 RFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERHEMQILSK
310 320 330 340 350 360
>>NP_997056 (OMIM: 608584,608595) neuropeptide S recepto (377 aa)
initn: 575 init1: 228 opt: 443 Z-score: 449.6 bits: 91.9 E(85289): 2.6e-18
Smith-Waterman score: 570; 32.0% identity (67.7% similar) in 300 aa overlap (42-336:52-337)
20 30 40 50 60 70
pF1KE0 EAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKH
.. .: ....... ::. ::.. :.:.
NP_997 SPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWR-RKKK
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE0 SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLL
::. ::. .:.:.: ... ..: .. : .: : .:::.::.:.::::: ..::::.:.
NP_997 SRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLV
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE0 LMSLDRCLAICQPLRSLR-RRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAV
.:.:: :: :.. :. .. :. .. .: .. : : . ::. : ...: .:::.
NP_997 SLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWAL
150 160 170 180 190 200
200 210 220 230 240
pF1KE0 FIQP--WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAA
. . : : :.: ... ::..:. ... ::.. :: .. :: .. .. .:
NP_997 WPDDSYWTP--YMTIVAFLVYFIPLTIISIMYGIVIRTIW--IKSKTYETVISNCSDGKL
210 220 230 240 250
250 260 270 280 290 300
pF1KE0 AGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD--ANAPK
.. .: :::::::...:...::.:::: ::.:.:. .. . .. .. .
NP_997 CSSYNR---------GLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQE
260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKS
. : .:.. : .::: :: :: .:.. .
NP_997 RFYASVIIQNLPALNSAINPLIYCVFSSSISFPCRVIRLRQLQEAALMLCPQRENWKGTW
310 320 330 340 350 360
>>NP_001287864 (OMIM: 608584,608595) neuropeptide S rece (390 aa)
initn: 575 init1: 228 opt: 443 Z-score: 449.5 bits: 92.0 E(85289): 2.7e-18
Smith-Waterman score: 570; 32.0% identity (67.7% similar) in 300 aa overlap (42-336:52-337)
20 30 40 50 60 70
pF1KE0 EAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKH
.. .: ....... ::. ::.. :.:.
NP_001 SPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLFVFTIVGNSVVLFSTWR-RKKK
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE0 SRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLL
::. ::. .:.:.: ... ..: .. : .: : .:::.::.:.::::: ..::::.:.
NP_001 SRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTYVLV
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE0 LMSLDRCLAICQPLRSLR-RRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAV
.:.:: :: :.. :. .. :. .. .: .. : : . ::. : ...: .:::.
NP_001 SLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQCWAL
150 160 170 180 190 200
200 210 220 230 240
pF1KE0 FIQP--WGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAA
. . : : :.: ... ::..:. ... ::.. :: .. :: .. .. .:
NP_001 WPDDSYWTP--YMTIVAFLVYFIPLTIISIMYGIVIRTIW--IKSKTYETVISNCSDGKL
210 220 230 240 250
250 260 270 280 290 300
pF1KE0 AGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD--ANAPK
.. .: :::::::...:...::.:::: ::.:.:. .. . .. .. .
NP_001 CSSYNR---------GLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFNLLPDTQE
260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKS
. : .:.. : .::: :: :: .:.. .
NP_001 RFYASVIIQNLPALNSAINPLIYCVFSSSISFPCRANSSVYLLACDVSVLWALVLTSEKE
310 320 330 340 350 360
389 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:55:42 2016 done: Sun Nov 6 17:55:43 2016
Total Scan time: 7.950 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]