Result of FASTA (omim) for
pFN21AE0499
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0499, 679 aa
1>>>pF1KE0499 679 - 679 aa - 679 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4599+/-0.000353; mu= 11.5178+/- 0.022
mean_var=143.7776+/-29.112, 0's: 0 Z-trim(118.6): 256 B-trim: 0 in 0/54
Lambda= 0.106962
statistics sampled from 31521 (31791) to 31521 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.373), width: 16
Scan time: 12.180
The best scores are: opt bits E(85289)
NP_001230881 (OMIM: 602591,615411) kinesin-like pr ( 686) 4458 699.7 9.2e-201
NP_004511 (OMIM: 602591,615411) kinesin-like prote ( 706) 4458 699.7 9.4e-201
NP_001230882 (OMIM: 602591,615411) kinesin-like pr ( 687) 3641 573.6 8.2e-163
NP_001091981 (OMIM: 602591,615411) kinesin-like pr ( 744) 3468 547.0 9.5e-155
NP_001284584 (OMIM: 604538) kinesin-like protein K ( 684) 2195 350.5 1.2e-95
NP_115948 (OMIM: 615142) kinesin-like protein KIF2 ( 673) 2048 327.8 8.1e-89
XP_011538843 (OMIM: 604538) PREDICTED: kinesin-lik ( 612) 2024 324.1 9.8e-88
XP_011538842 (OMIM: 604538) PREDICTED: kinesin-lik ( 612) 2024 324.1 9.8e-88
NP_001284586 (OMIM: 604538) kinesin-like protein K ( 612) 2024 324.1 9.8e-88
NP_001284585 (OMIM: 604538) kinesin-like protein K ( 671) 2024 324.1 1.1e-87
NP_006836 (OMIM: 604538) kinesin-like protein KIF2 ( 725) 2024 324.1 1.1e-87
NP_919289 (OMIM: 613747) kinesin-like protein KIF2 (1368) 1111 183.4 4.8e-45
XP_016870186 (OMIM: 613747) PREDICTED: kinesin-lik (1368) 1111 183.4 4.8e-45
XP_011516165 (OMIM: 613747) PREDICTED: kinesin-lik (1368) 1111 183.4 4.8e-45
XP_011516163 (OMIM: 613747) PREDICTED: kinesin-lik (1399) 1111 183.4 4.9e-45
XP_016870187 (OMIM: 613747) PREDICTED: kinesin-lik (1079) 891 149.4 6.6e-35
XP_005251508 (OMIM: 613747) PREDICTED: kinesin-lik (1007) 644 111.3 1.8e-23
XP_005246008 (OMIM: 605037) PREDICTED: kinesin-lik ( 984) 624 108.2 1.5e-22
XP_005246007 (OMIM: 605037) PREDICTED: kinesin-lik ( 985) 624 108.2 1.5e-22
XP_011540147 (OMIM: 605037) PREDICTED: kinesin-lik ( 992) 624 108.2 1.6e-22
XP_011540146 (OMIM: 605037) PREDICTED: kinesin-lik ( 997) 624 108.2 1.6e-22
XP_011540145 (OMIM: 605037) PREDICTED: kinesin-lik (1017) 624 108.2 1.6e-22
NP_001116291 (OMIM: 605037) kinesin-like protein K (1028) 624 108.2 1.6e-22
NP_065867 (OMIM: 605037) kinesin-like protein KIF1 (1029) 624 108.2 1.6e-22
XP_011540144 (OMIM: 605037) PREDICTED: kinesin-lik (1031) 624 108.2 1.6e-22
XP_011540143 (OMIM: 605037) PREDICTED: kinesin-lik (1038) 624 108.2 1.6e-22
XP_011540142 (OMIM: 605037) PREDICTED: kinesin-lik (1042) 624 108.2 1.6e-22
XP_011540141 (OMIM: 605037) PREDICTED: kinesin-lik (1043) 624 108.2 1.6e-22
XP_011540140 (OMIM: 605037) PREDICTED: kinesin-lik (1062) 624 108.2 1.6e-22
XP_011540139 (OMIM: 605037) PREDICTED: kinesin-lik (1063) 624 108.2 1.6e-22
NP_004789 (OMIM: 603754) kinesin-like protein KIF3 ( 747) 611 106.1 5e-22
XP_006714589 (OMIM: 604683) PREDICTED: kinesin-lik ( 724) 602 104.7 1.3e-21
NP_001287720 (OMIM: 604683) kinesin-like protein K ( 726) 602 104.7 1.3e-21
XP_016864485 (OMIM: 604683) PREDICTED: kinesin-lik ( 697) 596 103.8 2.3e-21
NP_008985 (OMIM: 604683) kinesin-like protein KIF3 ( 699) 596 103.8 2.3e-21
XP_016864484 (OMIM: 604683) PREDICTED: kinesin-lik ( 700) 596 103.8 2.3e-21
NP_001287721 (OMIM: 604683) kinesin-like protein K ( 702) 596 103.8 2.4e-21
NP_036442 (OMIM: 300521,300923) chromosome-associa (1232) 588 102.7 8.7e-21
NP_001092763 (OMIM: 609184) chromosome-associated (1234) 579 101.3 2.3e-20
XP_016859551 (OMIM: 604593,615282) PREDICTED: kine ( 957) 551 96.9 3.7e-19
NP_004513 (OMIM: 604593,615282) kinesin heavy chai ( 957) 551 96.9 3.7e-19
NP_004512 (OMIM: 602809) kinesin-1 heavy chain [Ho ( 963) 543 95.7 8.8e-19
NP_004975 (OMIM: 602821,604187) kinesin heavy chai (1032) 541 95.4 1.1e-18
NP_001305643 (OMIM: 604535) kinesin-like protein K ( 687) 507 90.0 3.2e-17
NP_001123571 (OMIM: 604535) kinesin-like protein K ( 687) 507 90.0 3.2e-17
NP_001305644 (OMIM: 604535) kinesin-like protein K ( 687) 507 90.0 3.2e-17
XP_011521380 (OMIM: 604535) PREDICTED: kinesin-lik ( 694) 507 90.0 3.2e-17
XP_011521381 (OMIM: 604535) PREDICTED: kinesin-lik ( 694) 507 90.0 3.2e-17
NP_001305641 (OMIM: 604535) kinesin-like protein K ( 724) 507 90.0 3.3e-17
XP_016878716 (OMIM: 604535) PREDICTED: kinesin-lik ( 768) 507 90.1 3.4e-17
>>NP_001230881 (OMIM: 602591,615411) kinesin-like protei (686 aa)
initn: 4458 init1: 4458 opt: 4458 Z-score: 3725.3 bits: 699.7 E(85289): 9.2e-201
Smith-Waterman score: 4458; 100.0% identity (100.0% similar) in 679 aa overlap (1-679:8-686)
10 20 30 40 50
pF1KE0 MVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEEIEPSPETPP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEEIEPSPETPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 PPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPSQFPEQSSSAQQNGSVSDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPSQFPEQSSSAQQNGSVSDIS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE0 PVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCM
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE0 IRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE0 QKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE0 HTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE0 KTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE0 IILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE0 HTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELTVDPTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELTVDPTAA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE0 GDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEM
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE0 EEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDK
610 620 630 640 650 660
660 670
pF1KE0 VKSFRAALQEEEQASKQINPKRPRAL
::::::::::::::::::::::::::
NP_001 VKSFRAALQEEEQASKQINPKRPRAL
670 680
>>NP_004511 (OMIM: 602591,615411) kinesin-like protein K (706 aa)
initn: 4458 init1: 4458 opt: 4458 Z-score: 3725.2 bits: 699.7 E(85289): 9.4e-201
Smith-Waterman score: 4458; 100.0% identity (100.0% similar) in 679 aa overlap (1-679:28-706)
10 20 30
pF1KE0 MVTSLNEDNESVTVEWIENGDTKGKEIDLESIF
:::::::::::::::::::::::::::::::::
NP_004 MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 SQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQEL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE0 LNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE0 EEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYA
610 620 630 640 650 660
640 650 660 670
pF1KE0 TQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
670 680 690 700
>>NP_001230882 (OMIM: 602591,615411) kinesin-like protei (687 aa)
initn: 4313 init1: 3634 opt: 3641 Z-score: 3044.0 bits: 573.6 E(85289): 8.2e-163
Smith-Waterman score: 4279; 97.1% identity (97.2% similar) in 679 aa overlap (1-679:28-687)
10 20 30
pF1KE0 MVTSLNEDNESVTVEWIENGDTKGKEIDLESIF
:::::::::::::::::::::::::::::::::
NP_001 MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 SQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQEL
::::::::::::: .:::::::::::::::::::::::::::
NP_001 SQFPEQSSSAQQN-------------------ARRKSNCVKEVEKLQEKREKRRLQQQEL
130 140 150 160
160 170 180 190 200 210
pF1KE0 REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE0 KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE0 RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE0 INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT
470 480 490 500 510 520
520 530 540 550 560 570
pF1KE0 LNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNE
530 540 550 560 570 580
580 590 600 610 620 630
pF1KE0 EEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYA
590 600 610 620 630 640
640 650 660 670
pF1KE0 TQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
650 660 670 680
>>NP_001091981 (OMIM: 602591,615411) kinesin-like protei (744 aa)
initn: 3464 init1: 3464 opt: 3468 Z-score: 2899.2 bits: 547.0 E(85289): 9.5e-155
Smith-Waterman score: 4332; 94.7% identity (94.7% similar) in 711 aa overlap (1-673:28-738)
10 20 30
pF1KE0 MVTSLNEDNESVTVEWIENGDTKGKEIDLESIF
:::::::::::::::::::::::::::::::::
NP_001 MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE0 SQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQEL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE0 REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE0 KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVET
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE0 IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLEL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE0 QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSC
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE0 RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAE
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE0 INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENT
490 500 510 520 530 540
520 530
pF1KE0 LNTLRYANRVKE--------------------------------------LTVDPTAAGD
:::::::::::: ::::::::::
NP_001 LNTLRYANRVKEFGISPSDIPFSQGSGSRPDLSPSYEYDDFSPSVTRVKELTVDPTAAGD
550 560 570 580 590 600
540 550 560 570 580 590
pF1KE0 VRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEE
610 620 630 640 650 660
600 610 620 630 640 650
pF1KE0 QVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVK
670 680 690 700 710 720
660 670
pF1KE0 SFRAALQEEEQASKQINPKRPRAL
::::::::::::::::::
NP_001 SFRAALQEEEQASKQINPKRPRAL
730 740
>>NP_001284584 (OMIM: 604538) kinesin-like protein KIF2C (684 aa)
initn: 2452 init1: 2050 opt: 2195 Z-score: 1838.1 bits: 350.5 E(85289): 1.2e-95
Smith-Waterman score: 2436; 57.2% identity (79.9% similar) in 677 aa overlap (2-677:31-684)
10 20 30
pF1KE0 MVTSLNEDNESVTVEWIENGDTKGKEIDLES
: ..: .. :.::: :.: :::::::...
NP_001 MAMDSSLQARLFPGLAIKIQRSNGLIHSANVRTVNLEKSCVSVEWAEGGATKGKEIDFDD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE0 IFSLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARA
. ..::.:. ..:. . : . . .: ::.: : : :... : : .
NP_001 VAAINPELLQLLPLHPKDNLPLQENVTIQKQK----RRSVNS-KIPAPKESLR---SRST
70 80 90 100 110
100 110 120 130 140 150
pF1KE0 RPSQFPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQ
: : : .::.: .. . ..:.:. : :::: ::::::...:::... :..
NP_001 RMSTVSELRITAQENDMEVELPAAANSRKQFSVPLRRKSCLVKEVEKMKNKREEKKAQNS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE0 ELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKET
:.: ::::. :.. ::.:. ::..::..:. .::: .:::.:::::::::::::::.:
NP_001 EMRMKRAQEYDSSFPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE0 QMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLV
:..:::.:::: ...::::: :::::.:::::.: ::.:::..: ::.::::::::::
NP_001 AKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE0 ETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKL
.:::: : ::::::::::::::::::::.::: :. ::::::.:.:::::. ..: :.::
NP_001 QTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRKL
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE0 ELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGN
:.::.::::::.::.:::::.:.:::::::::::::::::::. :. ..::.:.::.:.
NP_001 GLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGS
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE0 SCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEG
.::::::: ::..:::::: :::::: ::..::::::.:::::::::::::::::::.::
NP_001 ACRTSGQTFANSNSSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEG
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE0 AEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCE
::::::::::::::::::.:: ::::: :::::::::::::::::::::::::::..:::
NP_001 AEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCE
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE0 NTLNTLRYANRVKELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQ
::::::::.:::::. .:. : . ...:. . . : .:. .
NP_001 YTLNTLRYADRVKELSPHSGPSGEQLIQM-----ETEEMEACSNGALIP--GNLS----K
540 550 560 570 580
580 590 600 610 620 630
pF1KE0 NEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDS
.:::.: :. .:.::..:. :.::...:. . ..:.. ::: : ::::. :::...
NP_001 EEEELSSQMSSFNEAMTQIRELEEKAMEELKEIIQQGPDWLE----LSEMTEQPDYDLET
590 600 610 620 630
640 650 660 670
pF1KE0 YATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPK-RPRAL
.... :. : :. .. ::: .:..: :.: :::::.::. : ::.
NP_001 FVNKAESALAQQAKHFSALRDVIKALRLAMQLEEQASRQISSKKRPQ
640 650 660 670 680
>>NP_115948 (OMIM: 615142) kinesin-like protein KIF2B [H (673 aa)
initn: 2226 init1: 2016 opt: 2048 Z-score: 1715.6 bits: 327.8 E(85289): 8.1e-89
Smith-Waterman score: 2238; 56.5% identity (75.6% similar) in 669 aa overlap (1-662:45-667)
10 20 30
pF1KE0 MVTSLNEDNESVTVEWIENGDTKGKEIDLE
.:: .:..: :::::.:.. :::.::::
NP_115 PLKPLKPHFGDIQEGIYVAIQRSDKRIHLAVVTEINRENYWVTVEWVEKAVKKGKKIDLE
20 30 40 50 60 70
40 50 60 70 80
pF1KE0 SIFSLNPDLVPDEEIEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPS--RDNRVVGS
.:. ::: : : .: :::: : . : : ::.: .
NP_115 TILLLNPAL--DSAEHP---MPPPPLSPLALA---------------PSSAIRDQR---T
80 90 100 110
90 100 110 120 130 140
pF1KE0 ARARPSQFPEQSSSAQQNGSVSDIS-PVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRR
: ...:.....: .:. :. : . . ..:: :. :..::::.:::::
NP_115 ATKWVAMIPQKNQTA--SGDSLDVRVPSKPCLMK-----QKKSPCLWEIQKLQEQREKRR
120 130 140 150 160
150 160 170 180 190 200
pF1KE0 LQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLN
:::.: .:: ::.. ::::::: ::...: :: ... .: .::::::::::::::
NP_115 RLQQEIRARRALDVNTRNPNYEIMHMIEEYRRHLDSSKISVLEPPQEHRICVCVRKRPLN
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE0 KKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTA
..:: .::::.::.:: .:::::: ::::::::::.:::: ::.::::.: ::.::.:::
NP_115 QRETTLKDLDIITVPSDNVVMVHESKQKVDLTRYLQNQTFCFDHAFDDKASNELVYQFTA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE0 RPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPN
.::::.::..::::::::::::::::.:::::::: ::::::::::.:.::::.:.. .
NP_115 QPLVESIFRKGMATCFAYGQTGSGKTYTMGGDFSGTAQDCSKGIYALVAQDVFLLLRNST
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE0 YKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLI
:.::.:.::.::::::.:::.:::: : ::.:::::.::.:::::::.:: :::.::.:.
NP_115 YEKLDLKVYGTFFEIYGGKVYDLLNWKKKLQVLEDGNQQIQVVGLQEKEVCCVEEVLNLV
350 360 370 380 390 400
390 400 410 420 430 440
pF1KE0 DIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQT
.:::::::: :: .:::::::::::::::. .::::::.:::::::::::..:.:.
NP_115 EIGNSCRTSRQTPVNAHSSRSHAVFQIILKSGRIMHGKFSLVDLAGNERGADTTKASRKR
410 420 430 440 450 460
450 460 470 480 490 500
pF1KE0 RLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGM
.::::::::::::::::: :::.::::::::::::: ::::::::.:: :::::::::::
NP_115 QLEGAEINKSLLALKECILALGQNKPHTPFRASKLTLVLRDSFIGQNSSTCMIATISPGM
470 480 490 500 510 520
510 520 530 540 550 560
pF1KE0 ASCENTLNTLRYANRVKELTVD--PTAAGDVRPIMHHPPNQIDDLETQWGVGS-SPQRDD
.::::::::::::::::.:.:: : : :: :. : . :... : . : :::.
NP_115 TSCENTLNTLRYANRVKKLNVDVRPYHRGHY-PIGHEAPRM---LKSHIGNSEMSLQRDE
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE0 -LKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTE
.:. :.::. . . .. . . .: . : .:::. . : .
NP_115 FIKIPYVQSEEQ---------KEIEEVETLPTLLGKDTTISGKGSSQWLEN---IQERAG
590 600 610 620
630 640 650 660 670
pF1KE0 EVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
: .:.: .. .::::::: :::.. :.: . : :.
NP_115 GVHHDIDFCIARSLSILEQKIDALTEIQKKLKLLLADLHVKSKVE
630 640 650 660 670
>>XP_011538843 (OMIM: 604538) PREDICTED: kinesin-like pr (612 aa)
initn: 2283 init1: 2013 opt: 2024 Z-score: 1696.1 bits: 324.1 E(85289): 9.8e-88
Smith-Waterman score: 2265; 59.8% identity (81.6% similar) in 604 aa overlap (80-677:26-612)
50 60 70 80 90 100
pF1KE0 ETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS-----QFPEQSSSAQ
:: . : : .::: ..: . : .
XP_011 MSTVSELRITAQENDMEVELPAAANSRKQFSVPPAPTRPSCPAVAEIPLRMVSEE
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 QNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDAT
.. .: .: ..:. :::: ::::::...:::... :..:.: ::::. :..
XP_011 MEEQVHSIRGSSSANPV--NSVRRKSCLVKEVEKMKNKREEKKAQNSEMRMKRAQEYDSS
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 NPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSK
::.:. ::..::..:. .::: .:::.:::::::::::::::.: :..:::.::::
XP_011 FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSK
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 DVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFA
...::::: :::::.:::::.: ::.:::..: ::.::::::::::.:::: : :::::
XP_011 CLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFA
180 190 200 210 220 230
290 300 310 320 330 340
pF1KE0 YGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYS
:::::::::::::::.::: :. ::::::.:.:::::. ..: :.:: :.::.::::::.
XP_011 YGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYN
240 250 260 270 280 290
350 360 370 380 390 400
pF1KE0 GKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAH
::.:::::.:.:::::::::::::::::::. :. ..::.:.::.:..::::::: ::..
XP_011 GKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSN
300 310 320 330 340 350
410 420 430 440 450 460
pF1KE0 SSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKEC
:::::: :::::: ::..::::::.:::::::::::::::::::.:::::::::::::::
XP_011 SSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKEC
360 370 380 390 400 410
470 480 490 500 510 520
pF1KE0 IRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVK
:::::.:: ::::: :::::::::::::::::::::::::::..::: ::::::::.:::
XP_011 IRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVK
420 430 440 450 460 470
530 540 550 560 570 580
pF1KE0 ELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFH
::. .:. : . ...:. . . : .:. ..:::.: :. .:.
XP_011 ELSPHSGPSGEQLIQM-----ETEEMEACSNGALIP--GNLS----KEEEELSSQMSSFN
480 490 500 510 520
590 600 610 620 630 640
pF1KE0 EAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKI
::..:. :.::...:. . ..:.. ::: : ::::. :::....... :. : :.
XP_011 EAMTQIRELEEKAMEELKEIIQQGPDWLE----LSEMTEQPDYDLETFVNKAESALAQQA
530 540 550 560 570
650 660 670
pF1KE0 DILTELRDKVKSFRAALQEEEQASKQINPK-RPRAL
.. ::: .:..: :.: :::::.::. : ::.
XP_011 KHFSALRDVIKALRLAMQLEEQASRQISSKKRPQ
580 590 600 610
>>XP_011538842 (OMIM: 604538) PREDICTED: kinesin-like pr (612 aa)
initn: 2283 init1: 2013 opt: 2024 Z-score: 1696.1 bits: 324.1 E(85289): 9.8e-88
Smith-Waterman score: 2265; 59.8% identity (81.6% similar) in 604 aa overlap (80-677:26-612)
50 60 70 80 90 100
pF1KE0 ETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS-----QFPEQSSSAQ
:: . : : .::: ..: . : .
XP_011 MSTVSELRITAQENDMEVELPAAANSRKQFSVPPAPTRPSCPAVAEIPLRMVSEE
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 QNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDAT
.. .: .: ..:. :::: ::::::...:::... :..:.: ::::. :..
XP_011 MEEQVHSIRGSSSANPV--NSVRRKSCLVKEVEKMKNKREEKKAQNSEMRMKRAQEYDSS
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 NPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSK
::.:. ::..::..:. .::: .:::.:::::::::::::::.: :..:::.::::
XP_011 FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSK
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 DVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFA
...::::: :::::.:::::.: ::.:::..: ::.::::::::::.:::: : :::::
XP_011 CLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFA
180 190 200 210 220 230
290 300 310 320 330 340
pF1KE0 YGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYS
:::::::::::::::.::: :. ::::::.:.:::::. ..: :.:: :.::.::::::.
XP_011 YGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYN
240 250 260 270 280 290
350 360 370 380 390 400
pF1KE0 GKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAH
::.:::::.:.:::::::::::::::::::. :. ..::.:.::.:..::::::: ::..
XP_011 GKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSN
300 310 320 330 340 350
410 420 430 440 450 460
pF1KE0 SSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKEC
:::::: :::::: ::..::::::.:::::::::::::::::::.:::::::::::::::
XP_011 SSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKEC
360 370 380 390 400 410
470 480 490 500 510 520
pF1KE0 IRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVK
:::::.:: ::::: :::::::::::::::::::::::::::..::: ::::::::.:::
XP_011 IRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVK
420 430 440 450 460 470
530 540 550 560 570 580
pF1KE0 ELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFH
::. .:. : . ...:. . . : .:. ..:::.: :. .:.
XP_011 ELSPHSGPSGEQLIQM-----ETEEMEACSNGALIP--GNLS----KEEEELSSQMSSFN
480 490 500 510 520
590 600 610 620 630 640
pF1KE0 EAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKI
::..:. :.::...:. . ..:.. ::: : ::::. :::....... :. : :.
XP_011 EAMTQIRELEEKAMEELKEIIQQGPDWLE----LSEMTEQPDYDLETFVNKAESALAQQA
530 540 550 560 570
650 660 670
pF1KE0 DILTELRDKVKSFRAALQEEEQASKQINPK-RPRAL
.. ::: .:..: :.: :::::.::. : ::.
XP_011 KHFSALRDVIKALRLAMQLEEQASRQISSKKRPQ
580 590 600 610
>>NP_001284586 (OMIM: 604538) kinesin-like protein KIF2C (612 aa)
initn: 2283 init1: 2013 opt: 2024 Z-score: 1696.1 bits: 324.1 E(85289): 9.8e-88
Smith-Waterman score: 2265; 59.8% identity (81.6% similar) in 604 aa overlap (80-677:26-612)
50 60 70 80 90 100
pF1KE0 ETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS-----QFPEQSSSAQ
:: . : : .::: ..: . : .
NP_001 MSTVSELRITAQENDMEVELPAAANSRKQFSVPPAPTRPSCPAVAEIPLRMVSEE
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 QNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDAT
.. .: .: ..:. :::: ::::::...:::... :..:.: ::::. :..
NP_001 MEEQVHSIRGSSSANPV--NSVRRKSCLVKEVEKMKNKREEKKAQNSEMRMKRAQEYDSS
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 NPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSK
::.:. ::..::..:. .::: .:::.:::::::::::::::.: :..:::.::::
NP_001 FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSK
120 130 140 150 160 170
230 240 250 260 270 280
pF1KE0 DVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFA
...::::: :::::.:::::.: ::.:::..: ::.::::::::::.:::: : :::::
NP_001 CLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFA
180 190 200 210 220 230
290 300 310 320 330 340
pF1KE0 YGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYS
:::::::::::::::.::: :. ::::::.:.:::::. ..: :.:: :.::.::::::.
NP_001 YGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYN
240 250 260 270 280 290
350 360 370 380 390 400
pF1KE0 GKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAH
::.:::::.:.:::::::::::::::::::. :. ..::.:.::.:..::::::: ::..
NP_001 GKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSN
300 310 320 330 340 350
410 420 430 440 450 460
pF1KE0 SSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKEC
:::::: :::::: ::..::::::.:::::::::::::::::::.:::::::::::::::
NP_001 SSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKEC
360 370 380 390 400 410
470 480 490 500 510 520
pF1KE0 IRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVK
:::::.:: ::::: :::::::::::::::::::::::::::..::: ::::::::.:::
NP_001 IRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVK
420 430 440 450 460 470
530 540 550 560 570 580
pF1KE0 ELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFH
::. .:. : . ...:. . . : .:. ..:::.: :. .:.
NP_001 ELSPHSGPSGEQLIQM-----ETEEMEACSNGALIP--GNLS----KEEEELSSQMSSFN
480 490 500 510 520
590 600 610 620 630 640
pF1KE0 EAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKI
::..:. :.::...:. . ..:.. ::: : ::::. :::....... :. : :.
NP_001 EAMTQIRELEEKAMEELKEIIQQGPDWLE----LSEMTEQPDYDLETFVNKAESALAQQA
530 540 550 560 570
650 660 670
pF1KE0 DILTELRDKVKSFRAALQEEEQASKQINPK-RPRAL
.. ::: .:..: :.: :::::.::. : ::.
NP_001 KHFSALRDVIKALRLAMQLEEQASRQISSKKRPQ
580 590 600 610
>>NP_001284585 (OMIM: 604538) kinesin-like protein KIF2C (671 aa)
initn: 2283 init1: 2013 opt: 2024 Z-score: 1695.6 bits: 324.1 E(85289): 1.1e-87
Smith-Waterman score: 2265; 59.8% identity (81.6% similar) in 604 aa overlap (80-677:85-671)
50 60 70 80 90 100
pF1KE0 ETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS-----QFPEQSSSAQ
:: . : : .::: ..: . : .
NP_001 SRSTRMSTVSELRITAQENDMEVELPAAANSRKQFSVPPAPTRPSCPAVAEIPLRMVSEE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE0 QNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDAT
.. .: .: ..:. :::: ::::::...:::... :..:.: ::::. :..
NP_001 MEEQVHSIRGSSSANPV--NSVRRKSCLVKEVEKMKNKREEKKAQNSEMRMKRAQEYDSS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE0 NPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSK
::.:. ::..::..:. .::: .:::.:::::::::::::::.: :..:::.::::
NP_001 FPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE0 DVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFA
...::::: :::::.:::::.: ::.:::..: ::.::::::::::.:::: : :::::
NP_001 CLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE0 YGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYS
:::::::::::::::.::: :. ::::::.:.:::::. ..: :.:: :.::.::::::.
NP_001 YGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYN
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE0 GKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAH
::.:::::.:.:::::::::::::::::::. :. ..::.:.::.:..::::::: ::..
NP_001 GKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSN
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE0 SSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKEC
:::::: :::::: ::..::::::.:::::::::::::::::::.:::::::::::::::
NP_001 SSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKEC
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE0 IRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVK
:::::.:: ::::: :::::::::::::::::::::::::::..::: ::::::::.:::
NP_001 IRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVK
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE0 ELTVDPTAAGDVRPIMHHPPNQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFH
::. .:. : . ...:. . . : .:. ..:::.: :. .:.
NP_001 ELSPHSGPSGEQLIQM-----ETEEMEACSNGALIP--GNLS----KEEEELSSQMSSFN
540 550 560 570 580
590 600 610 620 630 640
pF1KE0 EAVSQMVEMEEQVVEDHRAVFQESIRWLEDEKALLEMTEEVDYDVDSYATQLEAILEQKI
::..:. :.::...:. . ..:.. ::: : ::::. :::....... :. : :.
NP_001 EAMTQIRELEEKAMEELKEIIQQGPDWLE----LSEMTEQPDYDLETFVNKAESALAQQA
590 600 610 620 630
650 660 670
pF1KE0 DILTELRDKVKSFRAALQEEEQASKQINPK-RPRAL
.. ::: .:..: :.: :::::.::. : ::.
NP_001 KHFSALRDVIKALRLAMQLEEQASRQISSKKRPQ
640 650 660 670
679 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:08:38 2016 done: Mon Nov 7 00:08:40 2016
Total Scan time: 12.180 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]