Result of FASTA (omim) for
pFN21AE0498
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0498, 1054 aa
1>>>pF1KE0498 1054 - 1054 aa - 1054 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5133+/-0.000414; mu= 16.6900+/- 0.026
mean_var=107.2701+/-21.065, 0's: 0 Z-trim(114.1): 252 B-trim: 0 in 0/53
Lambda= 0.123833
statistics sampled from 23495 (23753) to 23495 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.279), width: 16
Scan time: 12.950
The best scores are: opt bits E(85289)
XP_005262518 (OMIM: 300012) PREDICTED: probable gl (1054) 6969 1256.7 0
NP_003060 (OMIM: 300012) probable global transcrip (1054) 6969 1256.7 0
XP_005262519 (OMIM: 300012) PREDICTED: probable gl (1048) 6931 1249.9 0
NP_001269803 (OMIM: 300012) probable global transc (1070) 6927 1249.2 0
XP_016885240 (OMIM: 300012) PREDICTED: probable gl (1036) 3600 654.8 7e-187
XP_016885239 (OMIM: 300012) PREDICTED: probable gl (1042) 3600 654.8 7.1e-187
XP_006724845 (OMIM: 300012) PREDICTED: probable gl (1042) 3600 654.8 7.1e-187
NP_001269804 (OMIM: 300012) probable global transc (1058) 3600 654.8 7.2e-187
NP_003592 (OMIM: 603375) SWI/SNF-related matrix-as (1052) 2887 527.4 1.6e-148
NP_065971 (OMIM: 610528,615032) chromodomain-helic (2302) 1166 220.2 1.1e-55
NP_001164100 (OMIM: 610528,615032) chromodomain-he (2581) 1166 220.2 1.2e-55
XP_016879217 (OMIM: 616936) PREDICTED: chromodomai (2237) 1155 218.2 4.1e-55
XP_016879216 (OMIM: 616936) PREDICTED: chromodomai (2375) 1155 218.2 4.3e-55
XP_005256233 (OMIM: 616936) PREDICTED: chromodomai (2391) 1155 218.3 4.3e-55
XP_016879215 (OMIM: 616936) PREDICTED: chromodomai (2424) 1155 218.3 4.3e-55
XP_016879214 (OMIM: 616936) PREDICTED: chromodomai (2431) 1155 218.3 4.3e-55
XP_016879213 (OMIM: 616936) PREDICTED: chromodomai (2447) 1155 218.3 4.4e-55
NP_079410 (OMIM: 616936) chromodomain-helicase-DNA (2881) 1155 218.3 5e-55
XP_016879212 (OMIM: 616936) PREDICTED: chromodomai (2881) 1155 218.3 5e-55
XP_005256229 (OMIM: 616936) PREDICTED: chromodomai (2881) 1155 218.3 5e-55
XP_016879211 (OMIM: 616936) PREDICTED: chromodomai (2882) 1155 218.3 5e-55
XP_016879210 (OMIM: 616936) PREDICTED: chromodomai (2897) 1155 218.3 5e-55
NP_001295248 (OMIM: 616936) chromodomain-helicase- (2897) 1155 218.3 5e-55
XP_006721344 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_005256225 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_016879208 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_011521649 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_016879209 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_006721346 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_016879207 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_005256226 (OMIM: 616936) PREDICTED: chromodomai (2898) 1155 218.3 5e-55
XP_011515862 (OMIM: 189960,214800,608892,612370) P (1621) 1146 216.5 9.5e-55
XP_016869102 (OMIM: 189960,214800,608892,612370) P (2996) 1146 216.7 1.6e-54
NP_060250 (OMIM: 189960,214800,608892,612370) chro (2997) 1146 216.7 1.6e-54
XP_011515857 (OMIM: 189960,214800,608892,612370) P (3026) 1146 216.7 1.6e-54
XP_011515855 (OMIM: 189960,214800,608892,612370) P (3027) 1146 216.7 1.6e-54
XP_011515856 (OMIM: 189960,214800,608892,612370) P (3027) 1146 216.7 1.6e-54
XP_016869101 (OMIM: 189960,214800,608892,612370) P (3027) 1146 216.7 1.6e-54
XP_016883593 (OMIM: 616114) PREDICTED: chromodomai (2378) 1143 216.1 1.9e-54
XP_016883592 (OMIM: 616114) PREDICTED: chromodomai (2381) 1143 216.1 1.9e-54
XP_016883591 (OMIM: 616114) PREDICTED: chromodomai (2424) 1143 216.1 1.9e-54
XP_016883589 (OMIM: 616114) PREDICTED: chromodomai (2693) 1143 216.1 2.1e-54
XP_005260630 (OMIM: 616114) PREDICTED: chromodomai (2693) 1143 216.1 2.1e-54
XP_011527382 (OMIM: 616114) PREDICTED: chromodomai (2713) 1143 216.1 2.1e-54
NP_115597 (OMIM: 616114) chromodomain-helicase-DNA (2715) 1143 216.1 2.1e-54
XP_016883588 (OMIM: 616114) PREDICTED: chromodomai (2716) 1143 216.1 2.1e-54
NP_004275 (OMIM: 613039) chromodomain-helicase-DNA ( 897) 1089 206.2 6.9e-52
XP_016858348 (OMIM: 613039) PREDICTED: chromodomai ( 825) 1008 191.7 1.5e-47
XP_016858347 (OMIM: 613039) PREDICTED: chromodomai ( 825) 1008 191.7 1.5e-47
NP_006653 (OMIM: 136140,611421) helicase SRCAP [Ho (3230) 916 175.6 3.9e-42
>>XP_005262518 (OMIM: 300012) PREDICTED: probable global (1054 aa)
initn: 6969 init1: 6969 opt: 6969 Z-score: 6728.8 bits: 1256.7 E(85289): 0
Smith-Waterman score: 6969; 100.0% identity (100.0% similar) in 1054 aa overlap (1-1054:1-1054)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
::::::::::::::::::::::::::::::::::
XP_005 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
1030 1040 1050
>>NP_003060 (OMIM: 300012) probable global transcription (1054 aa)
initn: 6969 init1: 6969 opt: 6969 Z-score: 6728.8 bits: 1256.7 E(85289): 0
Smith-Waterman score: 6969; 100.0% identity (100.0% similar) in 1054 aa overlap (1-1054:1-1054)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
::::::::::::::::::::::::::::::::::
NP_003 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
1030 1040 1050
>>XP_005262519 (OMIM: 300012) PREDICTED: probable global (1048 aa)
initn: 6961 init1: 6931 opt: 6931 Z-score: 6692.1 bits: 1249.9 E(85289): 0
Smith-Waterman score: 6931; 99.9% identity (100.0% similar) in 1048 aa overlap (1-1048:1-1048)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
:::::::::::::::::::::::::::.
XP_005 SLIEKENMEIEERERAEKKKRATKTPMI
1030 1040
>>NP_001269803 (OMIM: 300012) probable global transcript (1070 aa)
initn: 6927 init1: 6927 opt: 6927 Z-score: 6688.1 bits: 1249.2 E(85289): 0
Smith-Waterman score: 6927; 100.0% identity (100.0% similar) in 1047 aa overlap (1-1047:1-1047)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
:::::::::::::::::::::::::::
NP_001 SLIEKENMEIEERERAEKKKRATKTPMSQKRKAESATESSGKKDVKKVKS
1030 1040 1050 1060 1070
>>XP_016885240 (OMIM: 300012) PREDICTED: probable global (1036 aa)
initn: 6840 init1: 3600 opt: 3600 Z-score: 3476.1 bits: 654.8 E(85289): 7e-187
Smith-Waterman score: 6818; 98.8% identity (98.9% similar) in 1048 aa overlap (1-1048:1-1036)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
:: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RE------------EAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
950 960 970 980 990 1000
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
:::::::::::::::::::::::::::.
XP_016 SLIEKENMEIEERERAEKKKRATKTPMI
1010 1020 1030
>>XP_016885239 (OMIM: 300012) PREDICTED: probable global (1042 aa)
initn: 3600 init1: 3600 opt: 3600 Z-score: 3476.0 bits: 654.8 E(85289): 7.1e-187
Smith-Waterman score: 6856; 98.9% identity (98.9% similar) in 1054 aa overlap (1-1054:1-1042)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
:: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RE------------EAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
950 960 970 980 990 1000
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
::::::::::::::::::::::::::::::::::
XP_016 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
1010 1020 1030 1040
>>XP_006724845 (OMIM: 300012) PREDICTED: probable global (1042 aa)
initn: 3600 init1: 3600 opt: 3600 Z-score: 3476.0 bits: 654.8 E(85289): 7.1e-187
Smith-Waterman score: 6856; 98.9% identity (98.9% similar) in 1054 aa overlap (1-1054:1-1042)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
:: ::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RE------------EAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
950 960 970 980 990 1000
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
::::::::::::::::::::::::::::::::::
XP_006 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
1010 1020 1030 1040
>>NP_001269804 (OMIM: 300012) probable global transcript (1058 aa)
initn: 3600 init1: 3600 opt: 3600 Z-score: 3475.9 bits: 654.8 E(85289): 7.2e-187
Smith-Waterman score: 6814; 98.9% identity (98.9% similar) in 1047 aa overlap (1-1047:1-1035)
10 20 30 40 50 60
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKRFEFLLKQTELFAHFIQPSAQKSPTSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEMVIKEKSVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDEH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE0 REDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
:: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RE------------EAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQV
550 560 570 580
610 620 630 640 650 660
pF1KE0 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKL
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE0 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE0 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE0 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQKKIDGAEP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE0 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSPEEVMEYSA
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE0 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRIQYGTSKGK
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE0 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEFQRRCNTLI
950 960 970 980 990 1000
1030 1040 1050
pF1KE0 SLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
:::::::::::::::::::::::::::
NP_001 SLIEKENMEIEERERAEKKKRATKTPMSQKRKAESATESSGKKDVKKVKS
1010 1020 1030 1040 1050
>>NP_003592 (OMIM: 603375) SWI/SNF-related matrix-associ (1052 aa)
initn: 5697 init1: 2873 opt: 2887 Z-score: 2787.5 bits: 527.4 E(85289): 1.6e-148
Smith-Waterman score: 5713; 81.8% identity (92.3% similar) in 1031 aa overlap (29-1044:11-1029)
10 20 30 40 50
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKG--EKKKE
: : .. . ::. :. .. ...:: :
NP_003 MSSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAA
10 20 30 40
60 70 80 90 100
pF1KE0 KNVSSFQLKLAAKA----------PKSEKEM---DPEYEEKMKADRAKRFEFLLKQTELF
. :.: : : : ..::. :: :::::..:::.:::.::::::::
NP_003 QAVASAASAGPADAEMEEIFDDASPGKQKEIQEPDPTYEEKMQTDRANRFEYLLKQTELF
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE0 AHFIQPSAQKSPTSPLNMKLGRPRIKKDEKQSLISAGDYRHRRTEQEEDEELLSESRKTS
::::::.:::.:::::.:: :::::::::::.:.:.:::::::::::::::::.:: :..
NP_003 AHFIQPAAQKTPTSPLKMKPGRPRIKKDEKQNLLSVGDYRHRRTEQEEDEELLTESSKAT
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE0 NVCIRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYL
::: ::: :::::: : :::::.:::::::::::::.:::::::::::::::::.::::.
NP_003 NVCTRFEDSPSYVKWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYM
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE0 KHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDV
:::::::::::::::::::::::.:::::::.:: .:..:::. ::::.:: ..::::::
NP_003 KHYRNIPGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEWDV
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE0 CVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQN
:::::::.::::::::::.:::::::::::::::::::::::::::.:::::::::::::
NP_003 CVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQN
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE0 NLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEK
::::::.::::::::::::::::::::::.::::::::::::: ::.::::::::.::::
NP_003 NLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKADVEK
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE0 SLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYL
:::::::.:::.:::::::::::.:::::::.:::.::::::::::::::::::::::::
NP_003 SLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYL
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE0 FDGAEPGPPYTTDEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWR
::::::::::::: :.:.:::::::::::: :::::::::::::::::.:::::::::::
NP_003 FDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWR
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE0 GYEYCRLDGQTPHEEREDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLAS
.::::::::::::.::.: .:.:.: :::.::.:::::::::::::::.
NP_003 NYEYCRLDGQTPHDERQD------------SINAYNEPNSTKFVFMLSTRAGGLGINLAT
530 540 550 560 570
590 600 610 620 630 640
pF1KE0 ADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSI
:::::::::::::::::::::::::::: : :::::.:::::::::::::::.:::::::
NP_003 ADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSI
580 590 600 610 620 630
650 660 670 680 690 700
pF1KE0 VIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNE
:::::::.::. ::..:.::::::::::::::::::::.::::: ::::: ::::::::
NP_003 VIQQGRLVDQNLNKIGKDEMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNE
640 650 660 670 680 690
710 720 730 740 750 760
pF1KE0 RLQKMGESSLRNFRMDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFRE
.:.:::::::::: :: :.:.:.:::::::::::....::::::::::::::::::::::
NP_003 KLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYFRE
700 710 720 730 740 750
770 780 790 800 810 820
pF1KE0 ALRVSEPKIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPA
:::::::: :::::::::::::::::::::::::::::::.:::::::::::::..:: :
NP_003 ALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKEILFYRKTIGYKVPRNPELPNAA
760 770 780 790 800 810
830 840 850 860 870 880
pF1KE0 LAQREEQKKIDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAR
::.::: ::: :: :. :: ::::::::::::::.:::::::::::::.:::::.::::
NP_003 QAQKEEQLKIDEAESLNDEELEEKEKLLTQGFTNWNKRDFNQFIKANEKWGRDDIENIAR
820 830 840 850 860 870
890 900 910 920 930 940
pF1KE0 EVEGKSPEEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKA
:::::.::::.:::::::::::::::::::::::::::::::::::::::::.::.::::
NP_003 EVEGKTPEEVIEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDTKIGRYKA
880 890 900 910 920 930
950 960 970 980 990 1000
pF1KE0 PFHQLRIQYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIK
:::::::.:::.:::::::::::::::::::.:::.::::.:::::.::.::::::::.:
NP_003 PFHQLRISYGTNKGKNYTEEEDRFLICMLHKLGFDKENVYDELRQCIRNSPQFRFDWFLK
940 950 960 970 980 990
1010 1020 1030 1040 1050
pF1KE0 SRTAMEFQRRCNTLISLIEKENMEIEERERAEKKKRATKTPMVKFSAFS
::::::.::::::::.:::.::::.::.:.::::::. :
NP_003 SRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPSTQKRKMDGAPDGRGRKKKL
1000 1010 1020 1030 1040 1050
NP_003 KL
>>NP_065971 (OMIM: 610528,615032) chromodomain-helicase- (2302 aa)
initn: 1006 init1: 405 opt: 1166 Z-score: 1121.0 bits: 220.2 E(85289): 1.1e-55
Smith-Waterman score: 1354; 36.3% identity (64.5% similar) in 722 aa overlap (13-695:363-1057)
10 20 30
pF1KE0 MEQDTAAVAATVAAADATATIVVIEDEQP-GPSTSQEE----
: .: . .. ... : : : : ::
NP_065 PILPEPVQEPDGETLPSMQFFVENPSEEDAAIVDKVLSMRIVKKELPSGQYTEAEEFFVK
340 350 360 370 380 390
40 50 60 70 80 90
pF1KE0 --GAAAAATE-ATAATEKGEKKKEKNVSSFQLKLAAKAPKSEKEMDPEYEEKMKADRAKR
. . : :: . . .:. ..... :. :.: ... .: . ...::
NP_065 YKNYSYLHCEWATISQLEKDKRIHQKLKRFKTKMAQMRHFFHEDEEPFNPDYVEVDR---
400 410 420 430 440
100 110 120 130 140 150
pF1KE0 FEFLLKQTELFAHFIQPSAQKSPTSPLNMKLGRPRIKKD-EKQSLISAGDYRHRRTEQEE
.: .. : :. . . : . : . : . .. : :. . : .
NP_065 ---ILDES----HSIDKDNGEPVIYYLVKWCSLPYEDSTWELKEDVDEGKIREFKRIQSR
450 460 470 480 490 500
160 170 180 190 200 210
pF1KE0 DEELLSESRKTSNVCIRFEVSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLG
:: .: ... ..:.: : . . ::.::..:.:::. . : : :::::::::
NP_065 HPELKRVNRPQASAWKKLELSHEYKNRNQLREYQLEGVNWLLFNWYNRQNCILADEMGLG
510 520 530 540 550 560
220 230 240 250 260 270
pF1KE0 KTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAF
::.:.::.: . . .: :: .:..: ::. :: ::. :. . .: . :. .: .
NP_065 KTIQSIAFLQEVYNV-GIHGPFLVIAPLSTITNWEREFNTWTE-MNTIVYHGSLASRQMI
570 580 590 600 610 620
280 290 300 310 320
pF1KE0 IRDEM---------MPG--EWDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSK
. :: .:: ..:. .:..::.... .....:: ..::::::.::.. :
NP_065 QQYEMYCKDSRGRLIPGAYKFDALITTFEMILSDCPELREIEWRCVIIDEAHRLKNRNCK
630 640 650 660 670 680
330 340 350 360 370 380
pF1KE0 LSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQK
: . .... ...:::::::::...::..::.:: :. : : ..: . : : ..
NP_065 LLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFLKDFGD---LKTEE
690 700 710 720 730
390 400 410 420 430 440
pF1KE0 LVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNS-S
:..:.:.:::..:::.: ::::.: ::.: : . :...:...: :: :... :.. .
NP_065 QVQKLQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLSKGA
740 750 760 770 780 790
450 460 470 480
pF1KE0 GKMDKMRLLNILMQLRKCCNHPYLFDGAEPG--PPYTTDEHI----------VSNSGKMV
:. . ::: .:.::::::::::..::: . :: : ..::.:
NP_065 GHTNMPNLLNTMMELRKCCNHPYLINGAEEKILTEFREACHIIPHDFHLQAMVRSAGKLV
800 810 820 830 840 850
490 500 510 520 530 540
pF1KE0 VLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPHEEREDKFLEVE
..:::: ::: : .:::::::.: ::::::: . : : : :.::.. . :.
NP_065 LIDKLLPKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYERIDGRVRGNLRQ-------
860 870 880 890 900 910
550 560 570 580 590 600
pF1KE0 FLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAH
::. :. :.:..:.:.: ::::::::::..::. :..::::::: ::::. : :
NP_065 -----AAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCH
920 930 940 950 960
610 620 630 640 650 660
pF1KE0 RIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQ--GRLIDQQS-NKLAKEEML
::::.: :.:.:::: :. :... ..: .:: ::. :.:. :: . . ....:.:.
NP_065 RIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRDGNITGIQQFSKKEIE
970 980 990 1000 1010 1020
670 680 690 700 710 720
pF1KE0 QMIRHGATHVFASKESE---LTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRMDIE
...:.:: .. ...: . .::: :: :
NP_065 DLLRKGAYAAIMEEDDEGSKFCEEDIDQILLRRTTTITIESEGKGSTFAKASFVASENRT
1030 1040 1050 1060 1070 1080
730 740 750 760 770 780
pF1KE0 QSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRPPKQ
NP_065 DISLDDPNFWQKWAKKADLDMDLLNSKNNLVIDTPRVRKQTRHFSTLKDDDLVEFSDLES
1090 1100 1110 1120 1130 1140
1054 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:41:21 2016 done: Mon Nov 7 20:41:23 2016
Total Scan time: 12.950 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]