Result of FASTA (ccds) for
pFN21AE0497
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0497, 400 aa
1>>>pF1KE0497 400 - 400 aa - 400 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0230+/-0.000801; mu= 9.4043+/- 0.048
mean_var=110.5751+/-22.051, 0's: 0 Z-trim(110.9): 31 B-trim: 0 in 0/51
Lambda= 0.121968
statistics sampled from 11914 (11938) to 11914 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.367), width: 16
Scan time: 3.080
The best scores are: opt bits E(32554)
CCDS11792.1 SIRT7 gene_id:51547|Hs108|chr17 ( 400) 2682 482.4 3.1e-136
CCDS12122.1 SIRT6 gene_id:51548|Hs108|chr19 ( 355) 610 117.8 1.6e-26
CCDS54199.1 SIRT6 gene_id:51548|Hs108|chr19 ( 328) 435 87.0 2.7e-17
>>CCDS11792.1 SIRT7 gene_id:51547|Hs108|chr17 (400 aa)
initn: 2682 init1: 2682 opt: 2682 Z-score: 2559.4 bits: 482.4 E(32554): 3.1e-136
Smith-Waterman score: 2682; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE0 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSL
310 320 330 340 350 360
370 380 390 400
pF1KE0 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
::::::::::::::::::::::::::::::::::::::::
CCDS11 CRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
370 380 390 400
>>CCDS12122.1 SIRT6 gene_id:51548|Hs108|chr19 (355 aa)
initn: 546 init1: 225 opt: 610 Z-score: 589.8 bits: 117.8 E(32554): 1.6e-26
Smith-Waterman score: 610; 43.2% identity (65.0% similar) in 280 aa overlap (77-346:22-287)
50 60 70 80 90 100
pF1KE0 EGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYT
:. : ::::. :: ::: : ... .: .:
CCDS12 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHT
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 GAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSE-AEPTLTHMSITRLHEQKLVQHVV
:::::::..:::.:::.::::. ..: . . : :.:: :::....:.. :.. .:
CCDS12 GAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLV
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 SQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTC
::: ::::.:::.:: ..::::::..: :..: . .::: :.. : . . ::: :
CCDS12 SQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC--KTQYVR--DTVVGT-MGLKATGRLC
120 130 140 150 160
230 240 250 260 270
pF1KE0 --------HKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKY
. : .:::::. . : . . : : ::. :: . ::.::.. .
CCDS12 TVAKARGLRACRGELRDTILDW-EDSLPDRDLA--LADEASRNADLSITLGTSLQI-RPS
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE0 PRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQ
: :: : .: ::::: : .: : :..:: :.:: :: .::::::: :.
CCDS12 GNLPLATK--RRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPA---WD
230 240 250 260 270
340 350 360 370 380 390
pF1KE0 DP-IFSLATPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKR
: .. : :
CCDS12 GPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPT
280 290 300 310 320 330
>>CCDS54199.1 SIRT6 gene_id:51548|Hs108|chr19 (328 aa)
initn: 582 init1: 225 opt: 435 Z-score: 423.9 bits: 87.0 E(32554): 2.7e-17
Smith-Waterman score: 558; 41.9% identity (63.2% similar) in 272 aa overlap (77-346:22-260)
50 60 70 80 90 100
pF1KE0 EGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYT
:. : ::::. :: ::: : ... .: .:
CCDS54 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHT
10 20 30 40 50
110 120 130 140 150 160
pF1KE0 GAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSE-AEPTLTHMSITRLHEQKLVQHVV
:::::::..:::.:::.::::. ..: . . : :.:: :::....:.. :.. .:
CCDS54 GAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLV
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE0 SQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTC
::: ::::.:::.:: ..::::::..: :..: . .::: :.. : . . ::: :
CCDS54 SQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC--KTQYVR--DTVVGT-MGLKATGRLC
120 130 140 150 160
230 240 250 260 270 280
pF1KE0 HKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTK
:... :: .: :: . ::.::.. . : ::
CCDS54 ---------TVAK--ARGL-----------RACRNADLSITLGTSLQI-RPSGNLPLATK
170 180 190 200
290 300 310 320 330 340
pF1KE0 PPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDP-IFSLA
: .: ::::: : .: : :..:: :.:: :: .::::::: :. : .. :
CCDS54 --RRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPA---WDGPRVLERA
210 220 230 240 250
350 360 370 380 390 400
pF1KE0 TPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
:
CCDS54 LPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPP
260 270 280 290 300 310
400 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:03:07 2016 done: Mon Nov 7 01:03:07 2016
Total Scan time: 3.080 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]