Result of FASTA (ccds) for
pFN21AB9956
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9956, 684 aa
1>>>pF1KB9956 684 - 684 aa - 684 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.8865+/-0.0012; mu= -0.8370+/- 0.071
mean_var=279.0776+/-59.596, 0's: 0 Z-trim(110.0): 24 B-trim: 274 in 2/51
Lambda= 0.076774
statistics sampled from 11304 (11319) to 11304 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.348), width: 16
Scan time: 3.800
The best scores are: opt bits E(32554)
CCDS33890.1 SKIL gene_id:6498|Hs108|chr3 ( 684) 4506 513.2 4.9e-145
CCDS46954.1 SKIL gene_id:6498|Hs108|chr3 ( 664) 4382 499.5 6.5e-141
CCDS46953.1 SKIL gene_id:6498|Hs108|chr3 ( 638) 2979 344.1 3.8e-94
CCDS39.1 SKI gene_id:6497|Hs108|chr1 ( 728) 1053 130.8 6.9e-30
>>CCDS33890.1 SKIL gene_id:6498|Hs108|chr3 (684 aa)
initn: 4506 init1: 4506 opt: 4506 Z-score: 2717.4 bits: 513.2 E(32554): 4.9e-145
Smith-Waterman score: 4506; 99.9% identity (100.0% similar) in 684 aa overlap (1-684:1-684)
10 20 30 40 50 60
pF1KB9 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHVNGKTINKVPTVKKEHLDDYGEA
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
CCDS33 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 QSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
610 620 630 640 650 660
670 680
pF1KB9 RQKLEMMIKELKLQILKSSKTAKE
::::::::::::::::::::::::
CCDS33 RQKLEMMIKELKLQILKSSKTAKE
670 680
>>CCDS46954.1 SKIL gene_id:6498|Hs108|chr3 (664 aa)
initn: 4382 init1: 4382 opt: 4382 Z-score: 2643.4 bits: 499.5 E(32554): 6.5e-141
Smith-Waterman score: 4382; 99.8% identity (100.0% similar) in 664 aa overlap (21-684:1-664)
10 20 30 40 50 60
pF1KB9 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHVNGKTINKVPTVKKEHLDDYGEA
:::::::::::::::::.::::::::::::::::::::::
CCDS46 MGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA
10 20 30 40
70 80 90 100 110 120
pF1KB9 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB9 QSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB9 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB9 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB9 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
590 600 610 620 630 640
670 680
pF1KB9 RQKLEMMIKELKLQILKSSKTAKE
::::::::::::::::::::::::
CCDS46 RQKLEMMIKELKLQILKSSKTAKE
650 660
>>CCDS46953.1 SKIL gene_id:6498|Hs108|chr3 (638 aa)
initn: 2947 init1: 2947 opt: 2979 Z-score: 1803.7 bits: 344.1 E(32554): 3.8e-94
Smith-Waterman score: 4113; 93.0% identity (93.3% similar) in 684 aa overlap (1-684:1-638)
10 20 30 40 50 60
pF1KB9 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHVNGKTINKVPTVKKEHLDDYGEA
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
CCDS46 MENLQTNFSLVQGSTKKLNGMGDDGSPPAKKMITDIHANGKTINKVPTVKKEHLDDYGEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHSQESMSPTV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 FLPLPSPQVLPGPLLIPSDSSTELTQTVLEGESISCFQVGGEKRLCLPQVLNSVLREFTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALLRPRTFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QTFVMHSHRSPDKRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEEMKEKFSMRSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KRNQSKTDAPSGMELQSWYPVIKQEGDHVSQTHSFLHPSYYLYMCDKVVAPNVSLTSAVS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 QSKELTKTEASKSISRQSEKAHSSGKLQKTVSYPDVSLEEQEKMDLKTSRELCSRLDASI
:::::::::: .:::
CCDS46 QSKELTKTEA----------------------------------------------NASI
430
490 500 510 520 530 540
pF1KB9 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SNNSTSKRKSESATCNLVRDINKVGIGLVAAASSPLLVKDVICEDDKGKIMEEVMRTYLK
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB9 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QQEKLNLILQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRMEEFYVEQ
500 510 520 530 540 550
610 620 630 640 650 660
pF1KB9 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KDLEKKLEQIMKQKCTCDSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQEREA
560 570 580 590 600 610
670 680
pF1KB9 RQKLEMMIKELKLQILKSSKTAKE
::::::::::::::::::::::::
CCDS46 RQKLEMMIKELKLQILKSSKTAKE
620 630
>>CCDS39.1 SKI gene_id:6497|Hs108|chr1 (728 aa)
initn: 1443 init1: 995 opt: 1053 Z-score: 650.1 bits: 130.8 E(32554): 6.9e-30
Smith-Waterman score: 1285; 38.1% identity (62.6% similar) in 661 aa overlap (83-637:14-671)
60 70 80 90 100 110
pF1KB9 HLDDYGEAPVETDGEHVKRTCTSVPETLHLNPSLKHTLAQFHLSSQSSLGGPAAFSARHS
.:.:..:: ::::::.:::::::::::: .
CCDS39 MEAAAGGRGCFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWA
10 20 30 40
120 130 140
pF1KB9 QESMS-----------------------PTVFLPL--PSPQVLPGPLLIPSDSSTELTQT
::... :.. :: : : :::::...::: ::: .:
CCDS39 QEAYKKESAKEAGAAAVPAPVPAATEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCET
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB9 VLEGESISCFQVGGEKRLCLPQVLNSVLREFTLQQINTVCDELYIYCSRCTSDQLHILKV
:::::.:::: :::::::::::.::::::.:.:::::.:::::.:::::::.:::.::::
CCDS39 VLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEILKV
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB9 LGILPFNAPSCGLITLTDAQRLCNALLRPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHE
.:::::.:::::::: :::.::::::: ..: . : : :. . . .: ::
CCDS39 MGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHE
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB9 CLGKCQGLFAPQFYVQPDAPCIQCLECCGMFAPQTFVMHSHRSPDKRTCHWGFESAKWHC
:.:::.::..:..: .:.: :::::.: :. :. ::.:::.. ..:::::::.::.:.
CCDS39 CFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRA
230 240 250 260 270 280
330 340 350 360
pF1KB9 YLHVNQKYLGTPEEKKLKIILEEMKEKF-------------------SMR-------SGK
:. ..: : : :. .: :...:::: :.: : .
CCDS39 YILLSQDYTGKEEQARLGRCLDDVKEKFDYGNKYKRRVPRVSSEPPASIRPKTDDTSSQS
290 300 310 320 330 340
370 380 390
pF1KB9 RNQSKTDAPSGM----------------------ELQSWYPVIKQEGDHVS-QTHSFLHP
:. : ::. .. : :... ..: . ....
CCDS39 PAPSEKDKPSSWLRTLAGSSNKSLGCVHPRQRLSAFRPWSPAVSASEKELSPHLPALIRD
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB9 SYYLYMC-DKVVAPNVSLTSAVSQSKELTKTEASKSISRQSEKAHSSGKLQK---TVSYP
:.: : . .:::::.:. .:.: ... . ..:: : . . .: ::. :
CCDS39 SFYSYKSFETAVAPNVALAPP-AQQKVVSSPPCAAAVSRAPEPLATCTQPRKRKLTVDTP
410 420 430 440 450 460
460 470 480 490 500
pF1KB9 D-------VSLEEQEKMDLKTSRELCSR--LDASISNNSTSKRKSESATCNL----VRDI
:. :..: : .. :. :: . .:.:. :. . : :.. .: .: .
CCDS39 GAPETLAPVAAPEEDK-DSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLGSPGARAL
470 480 490 500 510 520
510 520 530 540
pF1KB9 NKVGIGLVAAASSP------------LLVKDVICEDDKGKIMEEVMRTYLKQQEKLNLIL
.. .: :..: : . .. : :...::.. .::.:::. :
CCDS39 PSAVPDAAAPADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLSAAL
530 540 550 560 570 580
550 560 570 580 590 600
pF1KB9 QKKQQLQMEVKMLSSSKS--MKELTEEQQNLQKELESLQNEHAQRMEEFYVEQKDLEKKL
: :..:..:...: .:. ..: :: ..::.::.: :. :. ..:.: . :...:
CCDS39 QAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKREL
590 600 610 620 630 640
610 620 630 640 650 660
pF1KB9 EQIMKQKCTCDSNLEKDK-EAEYAGQLAELRQRLDHAEADRQELQDELRQEREARQKLEM
:: .: .::.. : . .:.:..:. .:.
CCDS39 EQA-RQARVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEK
650 660 670 680 690 700
670 680
pF1KB9 MIKELKLQILKSSKTAKE
CCDS39 VVKELQEQLWPRARPEAAGSEGAAELEP
710 720
684 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:59:28 2016 done: Sun Nov 6 11:59:29 2016
Total Scan time: 3.800 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]