Result of FASTA (omim) for
pFN21AB9895
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9895, 237 aa
1>>>pF1KB9895 237 - 237 aa - 237 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5876+/-0.00044; mu= 18.3444+/- 0.027
mean_var=63.3754+/-13.442, 0's: 0 Z-trim(109.6): 52 B-trim: 199 in 1/49
Lambda= 0.161107
statistics sampled from 17795 (17834) to 17795 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.565), E-opt: 0.2 (0.209), width: 16
Scan time: 5.280
The best scores are: opt bits E(85289)
NP_003208 (OMIM: 600748) bax inhibitor 1 isoform 1 ( 237) 1555 370.2 1.7e-102
NP_001092046 (OMIM: 600748) bax inhibitor 1 isofor ( 295) 1555 370.3 2e-102
XP_005269183 (OMIM: 600748) PREDICTED: bax inhibit ( 295) 1555 370.3 2e-102
NP_057140 (OMIM: 616874) protein lifeguard 4 isofo ( 238) 226 61.3 1.7e-09
NP_001269535 (OMIM: 616874) protein lifeguard 4 is ( 285) 226 61.4 1.9e-09
NP_001269539 (OMIM: 616874) protein lifeguard 4 is ( 207) 213 58.2 1.2e-08
NP_001308358 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
XP_011509929 (OMIM: 610364) PREDICTED: protein lif ( 311) 140 41.4 0.0021
NP_001308365 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_001308364 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_001308359 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_001308356 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_071435 (OMIM: 610364) protein lifeguard 3 isofo ( 311) 140 41.4 0.0021
NP_001308357 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_001308361 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_001308362 (OMIM: 610364) protein lifeguard 3 is ( 311) 140 41.4 0.0021
NP_001308367 (OMIM: 610364) protein lifeguard 3 is ( 200) 133 39.6 0.0048
>>NP_003208 (OMIM: 600748) bax inhibitor 1 isoform 1 [Ho (237 aa)
initn: 1555 init1: 1555 opt: 1555 Z-score: 1961.0 bits: 370.2 E(85289): 1.7e-102
Smith-Waterman score: 1555; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237)
10 20 30 40 50 60
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV
130 140 150 160 170 180
190 200 210 220 230
pF1KB9 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMILAMNEKDKKKEKK
190 200 210 220 230
>>NP_001092046 (OMIM: 600748) bax inhibitor 1 isoform 2 (295 aa)
initn: 1555 init1: 1555 opt: 1555 Z-score: 1959.7 bits: 370.3 E(85289): 2e-102
Smith-Waterman score: 1555; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:59-295)
10 20 30
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKV
::::::::::::::::::::::::::::::
NP_001 GCLPGPRGGPALFGLVTFGQSGDCCTDSGTMNIFDRKINFDALLKFSHITPSTQQHLKKV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 YASFALCMFVAAAGAYVHMVTHFIQAGLLSALGSLILMIWLMATPHSHETEQKRLGLLAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YASFALCMFVAAAGAYVHMVTHFIQAGLLSALGSLILMIWLMATPHSHETEQKRLGLLAG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 FAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSA
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 LSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDL
210 220 230 240 250 260
220 230
pF1KB9 FLDFITVFRKLMMILAMNEKDKKKEKK
:::::::::::::::::::::::::::
NP_001 FLDFITVFRKLMMILAMNEKDKKKEKK
270 280 290
>>XP_005269183 (OMIM: 600748) PREDICTED: bax inhibitor 1 (295 aa)
initn: 1555 init1: 1555 opt: 1555 Z-score: 1959.7 bits: 370.3 E(85289): 2e-102
Smith-Waterman score: 1555; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:59-295)
10 20 30
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKV
::::::::::::::::::::::::::::::
XP_005 GCLPGPRGGPALFGLVTFGQSGDCCTDSGTMNIFDRKINFDALLKFSHITPSTQQHLKKV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 YASFALCMFVAAAGAYVHMVTHFIQAGLLSALGSLILMIWLMATPHSHETEQKRLGLLAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YASFALCMFVAAAGAYVHMVTHFIQAGLLSALGSLILMIWLMATPHSHETEQKRLGLLAG
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 FAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FAFLTGVGLGPALEFCIAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSA
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 LSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLLLLSSLGNVFFGSIWLFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDL
210 220 230 240 250 260
220 230
pF1KB9 FLDFITVFRKLMMILAMNEKDKKKEKK
:::::::::::::::::::::::::::
XP_005 FLDFITVFRKLMMILAMNEKDKKKEKK
270 280 290
>>NP_057140 (OMIM: 616874) protein lifeguard 4 isoform b (238 aa)
initn: 129 init1: 75 opt: 226 Z-score: 291.5 bits: 61.3 E(85289): 1.7e-09
Smith-Waterman score: 226; 28.2% identity (64.8% similar) in 213 aa overlap (27-230:35-238)
10 20 30 40 50
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHM----VTH
:.:::. ..: ...... . : . :
NP_057 DPRYPRSSIEDDFNYGSSVASATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRT
10 20 30 40 50 60
60 70 80 90 100
pF1KB9 FIQAG----LLSALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIA
:.. . :: ::::: :.. :. . :.. . : :: ::..: .. .. .. :
NP_057 FVHESPALILLFALGSLGLIFALILNRHKYPLN---LYLLFGFTLLEALTVAVVVTF---
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 VNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIW
. :. ::. :. .: .:. .: ... .. .:. :.. : .: ::.. . :: :
NP_057 YDVYIILQAFILTTTVFFGLTVYTLQSKK-DFSKFGAGLFALLWILCLSGFLKFFFYSEI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 LFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMIL-AM
. . .: ...:::...::. ...: . ..:. :.:.::.:..: .:. .: :.
NP_057 MELVLAAAGALLFCGFIIYDTHSLMHKL--SPEEYVLAAISLYLDIINLFLHLLRFLEAV
180 190 200 210 220 230
230
pF1KB9 NEKDKKKEKK
:.:
NP_057 NKK
>>NP_001269535 (OMIM: 616874) protein lifeguard 4 isofor (285 aa)
initn: 129 init1: 75 opt: 226 Z-score: 290.5 bits: 61.4 E(85289): 1.9e-09
Smith-Waterman score: 226; 28.2% identity (64.8% similar) in 213 aa overlap (27-230:82-285)
10 20 30 40 50
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHM----VTH
:.:::. ..: ...... . : . :
NP_001 SATLNIIRFFHLRQSGRSGMVNIFYKGPTFLRKVYSILSLQVLLTTVTSTVFLYFESVRT
60 70 80 90 100 110
60 70 80 90 100
pF1KB9 FIQAG----LLSALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIA
:.. . :: ::::: :.. :. . :.. . : :: ::..: .. .. .. :
NP_001 FVHESPALILLFALGSLGLIFALILNRHKYPLN---LYLLFGFTLLEALTVAVVVTF---
120 130 140 150 160
110 120 130 140 150 160
pF1KB9 VNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIW
. :. ::. :. .: .:. .: ... .. .:. :.. : .: ::.. . :: :
NP_001 YDVYIILQAFILTTTVFFGLTVYTLQSKK-DFSKFGAGLFALLWILCLSGFLKFFFYSEI
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB9 LFQANLYVGLVVMCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMIL-AM
. . .: ...:::...::. ...: . ..:. :.:.::.:..: .:. .: :.
NP_001 MELVLAAAGALLFCGFIIYDTHSLMHKL--SPEEYVLAAISLYLDIINLFLHLLRFLEAV
230 240 250 260 270 280
230
pF1KB9 NEKDKKKEKK
:.:
NP_001 NKK
>>NP_001269539 (OMIM: 616874) protein lifeguard 4 isofor (207 aa)
initn: 129 init1: 75 opt: 213 Z-score: 276.0 bits: 58.2 E(85289): 1.2e-08
Smith-Waterman score: 221; 27.0% identity (64.0% similar) in 211 aa overlap (21-230:9-207)
10 20 30 40 50 60
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYASFALCMFVAAAGAYVHMVTHFIQAGLLS
: :.. . . .. .. .. .. ..:: .: ::
NP_001 MAAAWPPPPCTSEWVLLTTVTSTVFLYFESVRTFVHESPALI---LLF
10 20 30 40
70 80 90 100 110 120
pF1KB9 ALGSLILMIWLMATPHSHETEQKRLGLLAGFAFLTGVGLGPALEFCIAVNPSILPTAFMG
::::: :.. :. . :.. . : :: ::..: .. .. .. : . :. ::.
NP_001 ALGSLGLIFALILNRHKYPLN---LYLLFGFTLLEALTVAVVVTF---YDVYIILQAFIL
50 60 70 80 90
130 140 150 160 170 180
pF1KB9 TAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGSIWLFQANLYVGLVV
:. .: .:. .: ... .. .:. :.. : .: ::.. . :: : . . .: ..
NP_001 TTTVFFGLTVYTLQSKK-DFSKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALL
100 110 120 130 140 150
190 200 210 220 230
pF1KB9 MCGFVLFDTQLIIEKAEHGDQDYIWHCIDLFLDFITVFRKLMMIL-AMNEKDKKKEKK
.:::...::. ...: . ..:. :.:.::.:..: .:. .: :.:.:
NP_001 FCGFIIYDTHSLMHKL--SPEEYVLAAISLYLDIINLFLHLLRFLEAVNKK
160 170 180 190 200
>>NP_001308358 (OMIM: 610364) protein lifeguard 3 isofor (311 aa)
initn: 83 init1: 58 opt: 140 Z-score: 181.9 bits: 41.4 E(85289): 0.0021
Smith-Waterman score: 140; 23.4% identity (55.1% similar) in 214 aa overlap (27-225:99-307)
10 20 30 40 50
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYA--SFALCMFVA--AAGAYVHMVTH
..:::. : : . :: : ..:. :.
NP_001 PGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSA
70 80 90 100 110 120
60 70 80 90 100
pF1KB9 FIQAGLLSALGSLILMIWLMATPHSHETEQKRLG----LLAGFAFLTGVGLGP--ALEFC
:.. .. : ... . . ..:. ::. :.: : : ..
NP_001 FVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQT
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB9 IAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGS
:: ... :: .. .. . :: .. .. . . . ::.. : ...:. :
NP_001 KAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVL--LVTGIVTSIVLYFQYV
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB9 IWLFQANLYVGLVVMCGFVLF---DTQLIIEKAEH--GDQDYIWHCIDLFLDFITVFRKL
:: . ::..: ..: :.:: ::::.. . .: . .::: .... :.: .: .
NP_001 YWLHM--LYAALGAIC-FTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFV
250 260 270 280 290 300
230
pF1KB9 MMILAMNEKDKKKEKK
....
NP_001 LQLMGDRN
310
>>XP_011509929 (OMIM: 610364) PREDICTED: protein lifegua (311 aa)
initn: 83 init1: 58 opt: 140 Z-score: 181.9 bits: 41.4 E(85289): 0.0021
Smith-Waterman score: 140; 23.4% identity (55.1% similar) in 214 aa overlap (27-225:99-307)
10 20 30 40 50
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYA--SFALCMFVA--AAGAYVHMVTH
..:::. : : . :: : ..:. :.
XP_011 PGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSA
70 80 90 100 110 120
60 70 80 90 100
pF1KB9 FIQAGLLSALGSLILMIWLMATPHSHETEQKRLG----LLAGFAFLTGVGLGP--ALEFC
:.. .. : ... . . ..:. ::. :.: : : ..
XP_011 FVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQT
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB9 IAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGS
:: ... :: .. .. . :: .. .. . . . ::.. : ...:. :
XP_011 KAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVL--LVTGIVTSIVLYFQYV
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB9 IWLFQANLYVGLVVMCGFVLF---DTQLIIEKAEH--GDQDYIWHCIDLFLDFITVFRKL
:: . ::..: ..: :.:: ::::.. . .: . .::: .... :.: .: .
XP_011 YWLHM--LYAALGAIC-FTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFV
250 260 270 280 290 300
230
pF1KB9 MMILAMNEKDKKKEKK
....
XP_011 LQLMGDRN
310
>>NP_001308365 (OMIM: 610364) protein lifeguard 3 isofor (311 aa)
initn: 83 init1: 58 opt: 140 Z-score: 181.9 bits: 41.4 E(85289): 0.0021
Smith-Waterman score: 140; 23.4% identity (55.1% similar) in 214 aa overlap (27-225:99-307)
10 20 30 40 50
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYA--SFALCMFVA--AAGAYVHMVTH
..:::. : : . :: : ..:. :.
NP_001 PGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSA
70 80 90 100 110 120
60 70 80 90 100
pF1KB9 FIQAGLLSALGSLILMIWLMATPHSHETEQKRLG----LLAGFAFLTGVGLGP--ALEFC
:.. .. : ... . . ..:. ::. :.: : : ..
NP_001 FVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQT
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB9 IAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGS
:: ... :: .. .. . :: .. .. . . . ::.. : ...:. :
NP_001 KAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVL--LVTGIVTSIVLYFQYV
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB9 IWLFQANLYVGLVVMCGFVLF---DTQLIIEKAEH--GDQDYIWHCIDLFLDFITVFRKL
:: . ::..: ..: :.:: ::::.. . .: . .::: .... :.: .: .
NP_001 YWLHM--LYAALGAIC-FTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFV
250 260 270 280 290 300
230
pF1KB9 MMILAMNEKDKKKEKK
....
NP_001 LQLMGDRN
310
>>NP_001308364 (OMIM: 610364) protein lifeguard 3 isofor (311 aa)
initn: 83 init1: 58 opt: 140 Z-score: 181.9 bits: 41.4 E(85289): 0.0021
Smith-Waterman score: 140; 23.4% identity (55.1% similar) in 214 aa overlap (27-225:99-307)
10 20 30 40 50
pF1KB9 MNIFDRKINFDALLKFSHITPSTQQHLKKVYA--SFALCMFVA--AAGAYVHMVTH
..:::. : : . :: : ..:. :.
NP_001 PGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSA
70 80 90 100 110 120
60 70 80 90 100
pF1KB9 FIQAGLLSALGSLILMIWLMATPHSHETEQKRLG----LLAGFAFLTGVGLGP--ALEFC
:.. .. : ... . . ..:. ::. :.: : : ..
NP_001 FVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQT
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB9 IAVNPSILPTAFMGTAMIFTCFTLSALYARRRSYLFLGGILMSALSLLLLSSLGNVFFGS
:: ... :: .. .. . :: .. .. . . . ::.. : ...:. :
NP_001 KAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVL--LVTGIVTSIVLYFQYV
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB9 IWLFQANLYVGLVVMCGFVLF---DTQLIIEKAEH--GDQDYIWHCIDLFLDFITVFRKL
:: . ::..: ..: :.:: ::::.. . .: . .::: .... :.: .: .
NP_001 YWLHM--LYAALGAIC-FTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFV
250 260 270 280 290 300
230
pF1KB9 MMILAMNEKDKKKEKK
....
NP_001 LQLMGDRN
310
237 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:30:29 2016 done: Sun Nov 6 12:30:30 2016
Total Scan time: 5.280 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]