Result of FASTA (ccds) for
pFN21AB9894
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9894, 3661 aa
1>>>pF1KB9894 3661 - 3661 aa - 3661 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4698+/-0.00129; mu= 21.5078+/- 0.078
mean_var=87.2173+/-16.991, 0's: 0 Z-trim(101.8): 51 B-trim: 10 in 1/47
Lambda= 0.137332
statistics sampled from 6655 (6683) to 6655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.533), E-opt: 0.2 (0.205), width: 16
Scan time: 8.960
The best scores are: opt bits E(32554)
CCDS45430.1 SMG1 gene_id:23049|Hs108|chr16 (3661) 23886 4744.5 0
CCDS3124.1 ATR gene_id:545|Hs108|chr3 (2644) 485 108.1 9.4e-22
CCDS31669.1 ATM gene_id:472|Hs108|chr11 (3056) 466 104.3 1.4e-20
CCDS127.1 MTOR gene_id:2475|Hs108|chr1 (2549) 328 76.9 2.1e-12
>>CCDS45430.1 SMG1 gene_id:23049|Hs108|chr16 (3661 aa)
initn: 23886 init1: 23886 opt: 23886 Z-score: 25559.0 bits: 4744.5 E(32554): 0
Smith-Waterman score: 23886; 100.0% identity (100.0% similar) in 3661 aa overlap (1-3661:1-3661)
10 20 30 40 50 60
pF1KB9 MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRVNNVTSPEFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SNSAVVSRQRHDDTRVHADIQNDEKGGYSVNGGSGENTYGRKSLGQELRVNNVTSPEFTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 VQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTPELLCKCVKCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SSSAKDEVKLLYLCATYKALETVGEKKAFSSVMQLVMTSLQSILENVDTPELLCKCVKCI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 LLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GPPITEAYVTDVLYRVMRCVTAANQVFFSEAVLTAANECVGVLLGSLDPSMTIHCDMVIT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 YGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 YGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 VFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VFNVDNAKFVVIFDLSALTTIGNAKNSLIGMWALSPTVFALLSKNLMIVHSDLAVHFPAI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 QYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQAC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 SSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 ISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 VSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 QTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCIS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 SFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADW
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 AAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB9 AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB9 VKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB9 ALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLMELGLTAAKFARKRGNVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLMELGLTAAKFARKRGNVSL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB9 ATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB9 MEMLSSCAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MEMLSSCAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLST
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB9 LSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILGQLYHLSSVQAPEVAKSWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILGQLYHLSSVQAPEVAKSWA
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB9 ALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRP
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB9 AGIQDEDITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AGIQDEDITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRI
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB9 FSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHA
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB9 GELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPA
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB9 IVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB9 EDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRR
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB9 IQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB9 QDNYGDAIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QDNYGDAIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLA
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB9 AMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDL
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB9 HLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKR
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB9 WQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 WQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVM
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB9 KAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDN
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB9 VLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVL
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB9 HIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITR
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB9 SLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLE
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KB9 GAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLA
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KB9 SLLQEISTQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SLLQEISTQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQ
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KB9 LHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQELYRKYEMQYAPQPPPTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQELYRKYEMQYAPQPPPTVC
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KB9 QFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEG
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KB9 SLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQ
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KB9 LLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFRQIIFPEALRCLMKGEYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFRQIIFPEALRCLMKGEYTL
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KB9 ESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGEL
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KB9 IQPRNGSVDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IQPRNGSVDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREA
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KB9 RSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQ
3010 3020 3030 3040 3050 3060
3070 3080 3090 3100 3110 3120
pF1KB9 IVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQ
3070 3080 3090 3100 3110 3120
3130 3140 3150 3160 3170 3180
pF1KB9 VEAKDFGAESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VEAKDFGAESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLE
3130 3140 3150 3160 3170 3180
3190 3200 3210 3220 3230 3240
pF1KB9 TSISSCKTSLQRVQLHIAMFQWQHEDLLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TSISSCKTSLQRVQLHIAMFQWQHEDLLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIE
3190 3200 3210 3220 3230 3240
3250 3260 3270 3280 3290 3300
pF1KB9 TSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVT
3250 3260 3270 3280 3290 3300
3310 3320 3330 3340 3350 3360
pF1KB9 FLCSNIIHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FLCSNIIHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDT
3310 3320 3330 3340 3350 3360
3370 3380 3390 3400 3410 3420
pF1KB9 GLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVCETIQNLVDNIKTVLTGHNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVCETIQNLVDNIKTVLTGHNR
3370 3380 3390 3400 3410 3420
3430 3440 3450 3460 3470 3480
pF1KB9 QLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQV
3430 3440 3450 3460 3470 3480
3490 3500 3510 3520 3530 3540
pF1KB9 RSQEHVEMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RSQEHVEMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAA
3490 3500 3510 3520 3530 3540
3550 3560 3570 3580 3590 3600
pF1KB9 AVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGK
3550 3560 3570 3580 3590 3600
3610 3620 3630 3640 3650 3660
pF1KB9 AVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYEGWTAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYEGWTAW
3610 3620 3630 3640 3650 3660
pF1KB9 V
:
CCDS45 V
>>CCDS3124.1 ATR gene_id:545|Hs108|chr3 (2644 aa)
initn: 666 init1: 442 opt: 485 Z-score: 504.1 bits: 108.1 E(32554): 9.4e-22
Smith-Waterman score: 624; 36.8% identity (63.5% similar) in 299 aa overlap (2128-2426:2300-2566)
2100 2110 2120 2130 2140 2150
pF1KB9 WLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGL
. :: . ::::. . ::::: : .. :
CCDS31 LPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPK
2270 2280 2290 2300 2310 2320
2160 2170 2180 2190 2200 2210
pF1KB9 EDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGL
.::. : :.:.: :..: . ... ..: : :.: ::. . :.:.::.... :
CCDS31 DDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGL---
2330 2340 2350 2360 2370 2380
2220 2230 2240 2250 2260 2270
pF1KB9 YKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPL
: . : . :.: . :: . : :...::
CCDS31 ------RPILTKLYKEKGVYMTGK---------ELRQCML-P--KSAALS----------
2390 2400 2410
2280 2290 2300 2310 2320 2330
pF1KB9 HVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRH
. .:. : :. :: .. . . . : :. ..: ::::::::::::.::::::
CCDS31 EKLKVFREFLLPRHPP-IFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRH
2420 2430 2440 2450 2460 2470
2340 2350 2360 2370 2380 2390
pF1KB9 LDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCE
.:.:.: ::: ::.:.: :.::....::: ::::.:.:. ...: :.::.:: .::
CCDS31 GENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACE
2480 2490 2500 2510 2520 2530
2400 2410 2420 2430 2440 2450
pF1KB9 QVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMERE
....:: :: :...:..:..::::.:.
CCDS31 VTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNETGEVVNEKAKTHVLDIEQ
2540 2550 2560 2570 2580 2590
>>CCDS31669.1 ATM gene_id:472|Hs108|chr11 (3056 aa)
initn: 701 init1: 452 opt: 466 Z-score: 482.7 bits: 104.3 E(32554): 1.4e-20
Smith-Waterman score: 575; 32.6% identity (60.5% similar) in 347 aa overlap (2089-2426:2653-2961)
2060 2070 2080 2090 2100 2110
pF1KB9 LNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDT
: .:... .. . .. :: . .
CCDS31 LCDAYIILANLDATQWKTQRKGINIPADQPITKLKNLEDVVVPTMEIKVDHTGEYG--NL
2630 2640 2650 2660 2670 2680
2120 2130 2140 2150 2160 2170
pF1KB9 VTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFA
:::.: . . . . :: . .::::: : :: .::. : ..: ... ::..
CCDS31 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ
2690 2700 2710 2720 2730 2740
2180 2190 2200 2210 2220
pF1KB9 TINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPL--F------GLYKRWQQRE-AALQ
.. . .. :.:.::. :::...: :..:. : : .::.. . .:.:
CCDS31 RNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEFLVNNEDGAHKRYRPNDFSAFQ
2750 2760 2770 2780 2790 2800
2230 2240 2250 2260 2270 2280
pF1KB9 AQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELME
:: . : . . :.. .:: . :. . .:....
CCDS31 CQKKMMEVQKKS----FEEKYEVF--------------MDVCQNFQPVFRY-FCMEKFLD
2810 2820 2830 2840
2290 2300 2310 2320 2330 2340
pF1KB9 ATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGE
: :.. .:.::.:. :.::::.::::::..:.::. ..:
CCDS31 -----------------PAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAE
2850 2860 2870 2880
2350 2360 2370 2380 2390 2400
pF1KB9 VVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRET
.:::: .: ::.:: : .:: ::::.:..: ..:.:::::::: ::.....:: ..::
CCDS31 LVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQET
2890 2900 2910 2920 2930 2940
2410 2420 2430 2440 2450 2460
pF1KB9 LLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAE
:::..:...:::: :::
CCDS31 LLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNK
2950 2960 2970 2980 2990 3000
>>CCDS127.1 MTOR gene_id:2475|Hs108|chr1 (2549 aa)
initn: 1049 init1: 251 opt: 328 Z-score: 336.2 bits: 76.9 E(32554): 2.1e-12
Smith-Waterman score: 772; 27.1% identity (54.4% similar) in 641 aa overlap (1789-2425:1903-2429)
1760 1770 1780 1790 1800 1810
pF1KB9 AGQIPLDEDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVK--HAGELRQYLEHGLETTPT
:::.: : : .. . : .:...
CCDS12 LSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQI
1880 1890 1900 1910 1920 1930
1820 1830 1840 1850 1860 1870
pF1KB9 APWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQASGN
: .::::..:.. :. : . : .:: ... :. ..:: :.. : .. . ..:
CCDS12 DTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAAN
1940 1950 1960 1970 1980 1990
1880 1890 1900 1910 1920 1930
pF1KB9 KFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDK
: .: :. :: ::
CCDS12 K-------ILKNM---------CE--------HSN-------------------------
2000
1940 1950 1960 1970 1980 1990
pF1KB9 LSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNT
:.: :..:. :: ::..:: :.: .. . :. : .:: .
CCDS12 ------TLVQQAMMVSEELIRVAILWHEMW-----HEGLEEASRLYFGERNVK-----GM
2010 2020 2030 2040
2000 2010 2020 2030 2040 2050
pF1KB9 LRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENALEKLK
.. : . : :. .: : . :.. : ..: . . .:
CCDS12 FEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEA------QEWCR-----------KYMK
2050 2060 2070 2080 2090
2060 2070 2080 2090 2100 2110
pF1KB9 TPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSA-
. : ..: . ... .... . .: :.:. .:: : . :.:.:: .
CCDS12 SG-NVKDLTQAWDLYYHVFRRISKQLPQLTS--LELQYVSPKLLMCRDLELAVPGTYDPN
2100 2110 2120 2130 2140
2120 2130 2140 2150 2160 2170
pF1KB9 RDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNT
. . :.:.. .. .. .: .:.:: ..::.:. . .:.:: :::. :::.::....:::
CCDS12 QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNT
2150 2160 2170 2180 2190 2200
2180 2190 2200 2210 2220 2230
pF1KB9 MFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQD
..:. . . ..:.: ::.: :::: :: : .: . ..... :
CCDS12 LLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILL------
2210 2220 2230 2240 2250 2260
2240 2250 2260 2270 2280 2290
pF1KB9 SYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNL
.: : . ...: . : : :.:. .. : .
CCDS12 --------NIEHR----IMLRMAPDYDHLTLMQKVE-----------VFEHAVNNTAGDD
2270 2280 2290
2300 2310 2320 2330 2340 2350
pF1KB9 LAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDY
::: :: . . . :. .:.:: :::::::::.:::::: .:...: .:...:::.
CCDS12 LAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDF
2300 2310 2320 2330 2340 2350
2360 2370 2380 2390 2400 2410
pF1KB9 NVCFEKGKSL-RVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLL
. ::: . . . :::.:::.:. . .:. :::..: .:..:. :....:. .......:
CCDS12 GDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVL
2360 2370 2380 2390 2400 2410
2420 2430 2440 2450 2460 2470
pF1KB9 EAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNW
::::::::..:
CCDS12 EAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPES
2420 2430 2440 2450 2460 2470
3661 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:49:03 2016 done: Sun Nov 6 19:49:04 2016
Total Scan time: 8.960 Total Display time: 0.850
Function used was FASTA [36.3.4 Apr, 2011]