Result of FASTA (omim) for
pFN21AB9861
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9861, 408 aa
1>>>pF1KB9861 408 - 408 aa - 408 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5665+/-0.000354; mu= -0.7496+/- 0.022
mean_var=259.2639+/-55.862, 0's: 0 Z-trim(123.9): 134 B-trim: 2163 in 2/57
Lambda= 0.079653
statistics sampled from 44302 (44452) to 44302 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.823), E-opt: 0.2 (0.521), width: 16
Scan time: 10.230
The best scores are: opt bits E(85289)
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 2847 339.8 7.5e-93
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 1992 241.5 2.9e-63
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 1987 240.9 4.3e-63
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 1935 235.0 2.8e-61
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 795 104.0 8.4e-22
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 754 99.3 2.1e-20
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 700 93.1 1.6e-18
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 635 85.5 2.1e-16
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 607 82.3 2.2e-15
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 569 77.9 4.2e-14
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 570 78.2 5.5e-14
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 558 76.8 1.3e-13
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 552 76.0 1.6e-13
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 530 73.5 1e-12
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 512 71.5 4.9e-12
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 512 71.5 4.9e-12
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 501 70.1 9.5e-12
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 500 70.1 1.2e-11
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 496 69.6 1.5e-11
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 479 67.6 6.3e-11
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 470 66.6 1.3e-10
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 470 66.7 1.4e-10
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 466 66.1 1.6e-10
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 445 63.7 9.2e-10
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 430 62.1 3.5e-09
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 416 60.4 9.6e-09
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 400 58.7 4.3e-08
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 400 58.8 5.2e-08
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 381 56.5 2.2e-07
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 349 52.8 2.6e-06
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 349 52.8 2.7e-06
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 349 52.8 2.7e-06
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 349 52.8 2.7e-06
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 349 52.8 2.7e-06
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 349 52.9 2.7e-06
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 347 52.6 2.9e-06
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 347 52.6 3e-06
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 347 52.6 3e-06
XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 342 52.0 4.4e-06
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 331 50.7 8.9e-06
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 330 50.5 9.3e-06
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 330 50.5 9.3e-06
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 330 50.5 9.3e-06
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 330 50.7 1.3e-05
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 330 50.7 1.3e-05
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 330 50.7 1.3e-05
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 330 50.7 1.3e-05
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 330 50.7 1.3e-05
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 330 50.7 1.3e-05
NP_005188 (OMIM: 602628) forkhead box protein N3 i ( 468) 314 48.7 3.5e-05
>>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa)
initn: 2847 init1: 2847 opt: 2847 Z-score: 1788.0 bits: 339.8 E(85289): 7.5e-93
Smith-Waterman score: 2847; 100.0% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KB9 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 VARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 WSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 WSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSS
310 320 330 340 350 360
370 380 390 400
pF1KB9 LSDNFAATAAASGGGLRQRLRSHQGRGAGRAPVGRVGAAAVSGGGRGL
::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LSDNFAATAAASGGGLRQRLRSHQGRGAGRAPVGRVGAAAVSGGGRGL
370 380 390 400
>>NP_954714 (OMIM: 611085) forkhead box protein D4-like (416 aa)
initn: 2051 init1: 1512 opt: 1992 Z-score: 1256.9 bits: 241.5 E(85289): 2.9e-63
Smith-Waterman score: 1992; 94.1% identity (97.0% similar) in 303 aa overlap (1-302:1-303)
10 20 30 40 50 60
pF1KB9 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ
:::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::::
NP_954 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEARQQFLEQSLQPGLQ
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 VARWGGVALPREHIEGGG-PSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMA
:::::::::::::::::: :::::::::.:::::::::::::::::::::::::::::::
NP_954 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 ILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGT
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_954 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_954 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 ALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQ
: ::::::::::::::::::::::::: ::::::: .::::::::::::::::. .: .
NP_954 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 PSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPS
: :
NP_954 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ
310 320 330 340 350 360
>>NP_954586 (OMIM: 611086) forkhead box protein D4-like (417 aa)
initn: 2044 init1: 1522 opt: 1987 Z-score: 1253.7 bits: 240.9 E(85289): 4.3e-63
Smith-Waterman score: 1987; 94.1% identity (96.7% similar) in 303 aa overlap (1-302:1-303)
10 20 30 40 50 60
pF1KB9 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ
:::::::: ::::::::::::::::::::::::::::::::::: :::.:::::::::::
NP_954 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ
10 20 30 40 50 60
70 80 90 100 110
pF1KB9 VARWGGVALPREHIEGGG-PSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMA
:::::::::::::::::: :::::::::.:::::::::::::::::::::::::::::::
NP_954 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 ILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGT
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_954 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 ALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQ
: ::::::::::::::::::::::::: ::::::::.::::::::::: ::::. .: .
NP_954 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 PSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPS
: :
NP_954 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRICPRPRGATATCSSDHQ
310 320 330 340 350 360
>>NP_997188 (OMIM: 601092) forkhead box protein D4 [Homo (439 aa)
initn: 1819 init1: 1513 opt: 1935 Z-score: 1221.1 bits: 235.0 E(85289): 2.8e-61
Smith-Waterman score: 1935; 92.4% identity (95.0% similar) in 303 aa overlap (1-302:1-299)
10 20 30 40 50 60
pF1KB9 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ
:::::::: :::::::::::::::::::::::::::: ::: :::.:::::::::::
NP_997 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDED----EEEAASQQFLEQSLQPGLQ
10 20 30 40 50
70 80 90 100 110
pF1KB9 VARWGGVALPREHIEGGG-PSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMA
:::::::::::::::::: ::::::::::::::::::::::::::::::: :::::::::
NP_997 VARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 ILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGT
::::::::::::::::::: ::::::::::::::::::::::::::::::::::.::::.
NP_997 ILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
::::::::::::::::::::::::.::: :::::::::::::::::::::::::::::::
NP_997 YWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 ALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQ
: :::::::::::.:::::::::::::::::::::::::::::::::::::::. .: .
NP_997 APPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB9 PSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPS
: :
NP_997 PHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQ
300 310 320 330 340 350
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 798 init1: 692 opt: 795 Z-score: 512.4 bits: 104.0 E(85289): 8.4e-22
Smith-Waterman score: 817; 41.4% identity (57.7% similar) in 449 aa overlap (3-406:39-448)
10 20
pF1KB9 MNLPRAERPRSTPQRSL---RDSDGEDGKIDV
:: ::. :. : .. .:... :.
NP_004 EIMSSESSPAALSEADADIDVVGGGSGGGELPARSGPRA-PRDVLPHGHEPPAEEAEADL
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB9 LGEEEDEDEVEDEEEEA--SQKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGT
.::. : : .: :. . .:: .: :.: : ::
NP_004 AEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGP-------GP--------
70 80 90 100 110
90 100 110 120 130 140
pF1KB9 EFRAPPRSAAASEDARQP-AKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRR
.:: ..::. :.: .::::::::::::::::::.:::::: :: ::::::::::.
NP_004 ---GPPSGGAAT---RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYRE
120 130 140 150 160
150 160 170 180 190 200
pF1KB9 KFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRH
:::::::::::::::::::::::::::.::::.::.::: : :::::::::::::::::.
NP_004 KFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQ
170 180 190 200 210 220
210 220 230 240 250
pF1KB9 QLTPGAHLPHPFP---LPAAHAALHNPR---PG-PLLGAPA----LPQPVPGAYPNTAPG
: : ::: : : .. :: .: :: :: . : :. :: : ::
NP_004 PLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPP---PG
230 240 250 260 270 280
260 270 280 290 300
pF1KB9 RRPYALLHPHPPRYLLLSA-----------PAYAGAPKKAE--GADLATPGTLPVLQPSL
:. :::: . . .: :. :.:: . .. .: :. :. :.
NP_004 PAPHP--HPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPAS
290 300 310 320 330 340
310 320 330 340 350
pF1KB9 GPQPWEEGKGLASPPGG--GCI-SFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPS
: : :: . :. :: .: :. . :...: ::: ::..
NP_004 GSGPGPGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGL-----PTA-----LLRQ--
350 360 370 380
360 370 380 390 400
pF1KB9 SLSDNFAATAAASGGGLRQR-------LRSHQGRGA-----GRAPVGRVGAAAVSGGGRG
.:. . .. :...:.: :: . .: : :: :.. : :::.. ::.
NP_004 GLKTDAGGGAGGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGPPFAAAAGPGGQA
390 400 410 420 430 440
pF1KB9 L
NP_004 QVLAMLTAPALAPVAGHIRLSHPGDALLSSGSRFASKVAGLSGCHF
450 460 470 480 490
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 753 init1: 654 opt: 754 Z-score: 487.3 bits: 99.3 E(85289): 2.1e-20
Smith-Waterman score: 801; 42.9% identity (59.7% similar) in 427 aa overlap (4-402:44-436)
10 20 30
pF1KB9 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEE
:: : . .: :. ::: ... : ::
NP_004 AEETDIDVVGEGEDEEDEEEEDDDEGGGGGPRLAVPAQR-RRRRRSYAGED-ELEDLEEE
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB9 EDEDEVEDEEEEASQKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPP
::.:.. .. . :: : .:. ::: . . :
NP_004 EDDDDILLAPPAGG-----SPAPPGPAPAAGAGA--------GGGGGGGGAGG-------
80 90 100 110
100 110 120 130 140 150
pF1KB9 RSAAASEDARQP-AKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQ
...:. :..: .::::::::::::::::::.:::::: :: ::::::::::.::::::
NP_004 -GGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 NSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTP-G
:::::::::::::::::::::.::::.::.::: : :::::::::::::::::. : : .
NP_004 NSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLPPN
180 190 200 210 220 230
220 230 240 250 260
pF1KB9 AHLPHPFPLPAAHAA--LHNPRPGPLLGAPALPQPVPGAYPNTAPGRRPYAL-LHPH-PP
: . . : .: :: .: . : :: : : : :: . .: :.: : :. ::
NP_004 AAAAESLLLRGAGAAGGAGDPAAAAALFPPA-PPPPPHAY-GYGPYGCGYGLQLPPYAPP
240 250 260 270 280
270 280 290 300
pF1KB9 RYLLLSAPAYAGA------------PKKAEGADLAT------PGTLPVLQPSLGPQPWEE
:. .: : :.: : .. .:.:: : : . : :: :
NP_004 SALFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALP--GPLPASA
290 300 310 320 330 340
310 320 330 340 350 360
pF1KB9 GKGLASPPGGGCIS---FSIESIMQGVRG-AGTGAAQSLSPTAWSYCPLLQRPSSLSDNF
.: :. ::.. .. ::::::. : : :...:: . . .: . : :: ..
NP_004 AK--AGGPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASP---SPSPVAAPP
350 360 370 380 390 400
370 380 390 400
pF1KB9 AATAAASGGGLRQRLRSHQGRGAGRAPVGRVGAAAVSGGGRGL
: ..:::: . . . :. :. ..::: :
NP_004 AP--GSSGGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSSAALGTLHQGTALSSVENFT
410 420 430 440 450
NP_004 ARISNC
460
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 787 init1: 660 opt: 700 Z-score: 453.6 bits: 93.1 E(85289): 1.6e-18
Smith-Waterman score: 750; 45.5% identity (61.7% similar) in 347 aa overlap (65-405:106-410)
40 50 60 70 80 90
pF1KB9 DEDEVEDEEEEASQKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPR
:::. . ::::. : :. :
NP_036 QQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGS--GSAGGLAP-
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB9 SAAASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNS
:. . .::::::::::::::::::.:.::::::: :::.::::::.::::::::
NP_036 ----SKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNS
140 150 160 170 180
160 170 180 190 200 210
pF1KB9 IRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHL
:::::::::::::::::::.::::.::.::: :.::::::::::::::::::: ::
NP_036 IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQ---EHL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB9 PHPFPLPAAHAALHNPRPGPLLGAPALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSA
..:: .:: .: . .: .: :::.: :: :
NP_036 -------REQTALMMQS----FGAYSLAAAAGAA----GPYGRPYGL-HPAAAAGAY-SH
250 260 270 280
280 290 300 310 320
pF1KB9 PAYAGAPKKAEGADL--ATPGTLPVLQPSLGPQP-WEEGKGLA---SPPGGGCISFSIES
:: :.: : . . : : . ::: :.. : : :. : : : : ......:
NP_036 PAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPG-LQLQLNS
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB9 IMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGA
. .. .:::..: . . . . : ::: .:. . . :. :: .. ::
NP_036 LGAAAAAAGTAGAAGTTASLIKSEPS-ARPSFSIENIIGGGPAAPGG--------SAVGA
350 360 370 380 390
390 400
pF1KB9 GRAPVGRVGAAAVSGGGRGL
: : :... ::::
NP_036 GVA-----GGTGGSGGGSTAQSFLRPPGTVQSAALMATHQPLSLSRTTATIAPILSVPLS
400 410 420 430 440 450
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 626 init1: 547 opt: 635 Z-score: 415.7 bits: 85.5 E(85289): 2.1e-16
Smith-Waterman score: 653; 45.0% identity (61.5% similar) in 278 aa overlap (57-316:17-292)
30 40 50 60 70 80
pF1KB9 IDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ-VARWGGVALPREHIEGGGPSDPSEF
:.: :: : : : : . .
NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAA
10 20 30 40
90 100 110 120 130 140
pF1KB9 GTEFRAPPRSAAASEDARQP---AKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFP
: :: . . .. :.: .::::::::::.::. ..: .::::..: ::. ::
NP_036 GRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFA
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB9 YYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKR
.:: . :::::::::.:::::::.:::::.::::.::.::::. ::::::::::::::
NP_036 FYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRKR
110 120 130 140 150 160
210 220 230 240 250
pF1KB9 FKRHQLTP-GAHLPHPFPLPAAHAALHNPRPGPLLGAP---ALPQPVPGAY---PNTAPG
::: .: .: : : ::: .: . : ::: : .: : : : : : .. .
NP_036 FKRAELPAHAAAAPGP-PLPFPYAP-YAPAPGPALLVPPPSAGPGPSPPARLFSVDSLVN
170 180 190 200 210 220
260 270 280 290 300
pF1KB9 RRPY--ALLHPHPPRYLLLSAPAYAGAPKKAEGAD---LATPG--TLPVLQPSLGPQPWE
.: .: :.:: .: : : : : .. .: .::. .:. :: : :
NP_036 LQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPDRLVLPATRPGPGPLPAE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 EGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPSSLSDNFAAT
.::.:
NP_036 PLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
290 300 310
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 574 init1: 538 opt: 607 Z-score: 397.3 bits: 82.3 E(85289): 2.2e-15
Smith-Waterman score: 667; 40.6% identity (58.5% similar) in 342 aa overlap (86-400:30-350)
60 70 80 90 100 110
pF1KB9 QPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDAR--QPAKPPYSYI
:. .: :.:.. . : : .:::::::
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYI
10 20 30 40 50
120 130 140 150 160 170
pF1KB9 ALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPG
:::.::: ..:..::::.:: ::. :::.:: . :::::::::.:::::.::::: :
NP_004 ALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAG
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB9 HPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPG
.::::.::.::: ..:::..:::::::::::: .:. : :: :: .
NP_004 RPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAA
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB9 PLLGA-PALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATP
. :: :: : ::: . : : .: : :: : :: . .: .. : :
NP_004 IFPGAVPAARPPYPGA---VYAGYAPPSLAAP-PPVYY----PAASPGPCRVFGLVPERP
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB9 GTLPVLQPSLGPQPWEEGKGLASPPGGGCI--SFSIESIMQGVRGAGTGAAQSLSPTAWS
:.: ::: : : :::.: : . . : . :: .:. .:.:..
NP_004 -----LSPELGPAP--------SGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYA
240 250 260 270
360 370 380
pF1KB9 YC---PLLQRPSSL-SDNFAAT----------AAASGGGLRQRL----RSHQGR----GA
: :.. : :::. :..:.::.. . :. :. ::
NP_004 AAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGA
280 290 300 310 320 330
390 400
pF1KB9 GRAPVGRVGAAAVSGGGRGL
: :..:.:.
NP_004 CYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
340 350 360 370
>>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa)
initn: 540 init1: 510 opt: 569 Z-score: 374.2 bits: 77.9 E(85289): 4.2e-14
Smith-Waterman score: 569; 40.5% identity (57.2% similar) in 306 aa overlap (78-368:22-311)
50 60 70 80 90 100
pF1KB9 QKFLEQSLQPGLQVARWGGVALPREHIEGGGPSDPSEFGTEFRAPPRSAAASEDARQPAK
:: :. . : :: . ::: :. : :
NP_005 MSHLFDPRLPALAASPMLYLYGPERPG-LPLAF-APAAALAASGRAETPQK
10 20 30 40
110 120 130 140 150 160
pF1KB9 PPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVK
:::::::::.::: ..:..:.::.:: :: :::.:. . .:::::::::::::::::
NP_005 PPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVK
50 60 70 80 90 100
170 180 190 200 210 220
pF1KB9 IPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGA-HLPHPFPLPAAHAA
.::: :.::::.::.::: :::.::.. ::::: . . ::: . .: ..:
NP_005 VPREKGRPGKGSYWTLDPRCLDMFENGNY-RRRKR--KPKPGPGAPEAKRPRAETHQRSA
110 120 130 140 150 160
230 240 250 260 270 280
pF1KB9 LHNPRPGPLLGA--PALP--QPVPGAYPNTAPGRRPYALLH-PHPPRYLLLSAPAYAGAP
.:. : :. ::. : .:.. : : : :: : .. : ::
NP_005 EAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAA
170 180 190 200 210 220
290 300 310 320 330
pF1KB9 KKAEGADLAT---PGTLPVLQPSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGT
: : : ::. : :.:. .: :. ::::.::. : .:
NP_005 AVAVGQAARTGDGPGS-P-LRPASRSSPKSSDKSK---------SFSIDSILAGKQGQKP
230 240 250 260 270
340 350 360 370 380 390
pF1KB9 GAAQSL------SPTAWSYCPLLQRPSSLSDNFAATAAASGGGLRQRLRSHQGRGAGRAP
... : .: . :: ::: : :.
NP_005 PSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPL
280 290 300 310 320 330
400
pF1KB9 VGRVGAAAVSGGGRGL
NP_005 QVPDTVLHFQ
340
408 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:17:44 2016 done: Sun Nov 6 18:17:46 2016
Total Scan time: 10.230 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]