Result of FASTA (omim) for
pFN21AB9638
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9638, 451 aa
1>>>pF1KB9638 451 - 451 aa - 451 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0854+/-0.000333; mu= 9.0912+/- 0.021
mean_var=287.3739+/-58.168, 0's: 0 Z-trim(124.6): 87 B-trim: 0 in 0/59
Lambda= 0.075657
statistics sampled from 46476 (46585) to 46476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.546), width: 16
Scan time: 10.230
The best scores are: opt bits E(85289)
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 3199 362.1 1.7e-99
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 1240 148.4 4.2e-35
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 1183 142.1 2.9e-33
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 983 120.1 9.6e-27
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 701 89.4 1.9e-17
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 701 89.4 1.9e-17
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 701 89.4 1.9e-17
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 701 89.4 2e-17
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 701 89.4 2e-17
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 701 89.4 2e-17
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 701 89.5 2e-17
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 668 85.7 2.1e-16
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 672 86.5 2.3e-16
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 672 86.6 2.4e-16
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 672 86.6 2.5e-16
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 672 86.6 2.5e-16
NP_002688 (OMIM: 164175) POU domain, class 2, tran ( 766) 672 86.6 2.5e-16
XP_011507955 (OMIM: 164175) PREDICTED: POU domain, ( 769) 672 86.6 2.5e-16
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 651 83.9 7.8e-16
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 642 82.7 1.3e-15
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 634 82.0 2.8e-15
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 631 81.8 3.9e-15
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 610 79.3 1.6e-14
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 604 78.6 2.4e-14
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 526 70.3 1.1e-11
NP_001167002 (OMIM: 164177) POU domain, class 5, t ( 190) 515 68.7 1.5e-11
NP_976034 (OMIM: 164177) POU domain, class 5, tran ( 190) 515 68.7 1.5e-11
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 508 68.2 3.7e-11
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 401 56.9 1.8e-07
NP_001234923 (OMIM: 164176) POU domain, class 2, t ( 400) 387 55.1 3.9e-07
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 387 55.2 4.3e-07
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 387 55.2 4.4e-07
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 387 55.3 4.9e-07
XP_016882382 (OMIM: 164176) PREDICTED: POU domain, ( 608) 387 55.4 5.1e-07
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 382 54.7 6.3e-07
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 382 54.7 6.4e-07
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 382 54.7 6.6e-07
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 382 54.7 6.8e-07
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 382 54.8 7.3e-07
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 382 54.8 7.3e-07
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 382 54.8 7.3e-07
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 382 54.8 7.5e-07
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 382 54.9 8e-07
XP_016882380 (OMIM: 164176) PREDICTED: POU domain, ( 707) 382 54.9 8.1e-07
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 382 54.9 8.1e-07
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 382 54.9 8.1e-07
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 382 54.9 8.1e-07
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 382 54.9 8.1e-07
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 382 54.9 8.1e-07
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 382 54.9 8.2e-07
>>NP_002690 (OMIM: 602479) POU domain, class 3, transcri (451 aa)
initn: 3199 init1: 3199 opt: 3199 Z-score: 1907.3 bits: 362.1 E(85289): 1.7e-99
Smith-Waterman score: 3199; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)
10 20 30 40 50 60
pF1KB9 MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 GGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 VGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 LSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG
370 380 390 400 410 420
430 440 450
pF1KB9 GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
:::::::::::::::::::::::::::::::
NP_002 GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
430 440 450
>>NP_006227 (OMIM: 602480) POU domain, class 3, transcri (500 aa)
initn: 1088 init1: 1008 opt: 1240 Z-score: 751.2 bits: 148.4 E(85289): 4.2e-35
Smith-Waterman score: 1281; 50.5% identity (64.3% similar) in 493 aa overlap (11-451:39-500)
10 20 30 40
pF1KB9 MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERL
: :::::: : :.: .::....: ..
NP_006 YLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGD--
10 20 30 40 50 60
50 60 70 80
pF1KB9 HAGAAYREVQK-LMHHEWLGAGAGHPVGLAHPQW---LPTGGGGGG-----------DWA
.. . ::. .:. ....:: .. :: :: :: ...... :.
NP_006 --PSSVKMVQSDFMQGAMAASNGGHMLSHAH-QWVTALPHAAAAAAAAAAAAVEASSPWS
70 80 90 100 110 120
90 100 110 120
pF1KB9 GG---------------PHLEHGKAGGGGTGRADDGGGGGGFHARLV----------HQG
:. : .: ::.:: :: .: ..: : :::
NP_006 GSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGR-DDLHAGTALHHRGPPHLGPPPPPPHQG
130 140 150 160 170 180
130 140 150 160 170
pF1KB9 AAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGL-YAQAAYPGGGGGGLAGMLAA-
. .: : ...: . : . :. .::.:: : .: :.: ::: . :::.:
NP_006 HPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQ---PGGFT--VNGMLSAP
190 200 210 220 230
180 190 200 210 220 230
pF1KB9 -----GGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPG
:::::: : . .: : : : : : :.: : : : . : :
NP_006 PGPGGGGGGAGGGAQSLVHP-GLVRGDTPELAEH-HHHHHHHAHPHPPHPHHAQGPPHHG
240 250 260 270 280 290
240 250 260 270 280
pF1KB9 AGGGGSSVG-----EHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVF
.::::.. : :::::.:.:::::::::::::::::::::::::::::::::::::
NP_006 GGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVF
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB9 SQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEV
:::::::::::::::::::::::::::::::.:::.::::..::::::::::::::::::
NP_006 SQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEV
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB9 GVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPM
.:::::::::::::::::.:::.:::::::::::::::::::::::::::: . . :
NP_006 SVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTP-
420 430 440 450 460 470
410 420 430 440 450
pF1KB9 DDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
::::. ..: :: ::: :: : :::
NP_006 DDVYS--QVGT-------VSADTPPP--------HHGLQTSVQ
480 490 500
>>NP_005595 (OMIM: 600494) POU domain, class 3, transcri (443 aa)
initn: 1163 init1: 995 opt: 1183 Z-score: 718.1 bits: 142.1 E(85289): 2.9e-33
Smith-Waterman score: 1238; 51.1% identity (65.0% similar) in 460 aa overlap (22-427:11-441)
10 20 30 40 50 60
pF1KB9 MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGA
:. .:. . : .. . ::. :::.:.:.. .. ::
NP_005 MATAASNHYSLLTSSASIVHAEPPGGMQQGAGG-YREAQSLVQGDY-GA
10 20 30 40
70 80 90 100
pF1KB9 --GAGHPVGLAHPQW---LPTGGGGGGDWAGGPHLEHGKAGGGGT---------------
. :::.. :: :: : :::::: .:: : .:: :.
NP_005 LQSNGHPLSHAH-QWITALSHGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPS
50 60 70 80 90 100
110 120
pF1KB9 ------GRADDGGGGGGFHAR--------------------------LVHQGAAH--AGA
::.:. : :... . :::..: : . .
NP_005 VVVQQGGRGDELHGPGALQQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPG
110 120 130 140 150 160
130 140 150 160 170 180
pF1KB9 AWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPG
:: ....: :: :.: :::.: ::.: .. . :::.::: : :
NP_005 AWRSAAAAAHLPPSM----GASNGGL-----LYSQPSFT------VNGMLGAGGQPA--G
170 180 190 200
190 200 210 220 230 240
pF1KB9 LHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSD
::: .:.:. : : : : :.: : . :: :. . :::
NP_005 LHHHGLRDAHDE------PHHADHHPHPHSHPHQQPPPPPPPQGPPGHPGAHHD--PHSD
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB9 EDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM
::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNM
270 280 290 300 310 320
310 320 330 340 350 360
pF1KB9 CKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSA
:::::::::::::.::::::::..::::::::::::::::::.:::::::::::::::::
NP_005 CKLKPLLNKWLEEADSSSGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSA
330 340 350 360 370 380
370 380 390 400 410 420
pF1KB9 HEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASP
.:::.:::::::::::::::::::::::::::: .:. : .:::. .. : :..
NP_005 QEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGGT-LPGAEDVYGGSRDTPPHHGVQT
390 400 410 420 430 440
430 440 450
pF1KB9 PSAPPPPPPAALHHHHHHTLPGSVQ
:
NP_005 PVQ
>>NP_000298 (OMIM: 300039,304400) POU domain, class 3, t (361 aa)
initn: 1035 init1: 963 opt: 983 Z-score: 601.1 bits: 120.1 E(85289): 9.6e-27
Smith-Waterman score: 1064; 52.1% identity (68.4% similar) in 376 aa overlap (40-413:25-349)
10 20 30 40 50 60
pF1KB9 RGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWL-GAGA-GHPVG
.. :. .:. :::.. ..: :. . :::.:
NP_000 MATAASNPYSILSSTSLVHADSAGMQQGSPFRNPQKLLQSDYLQGVPSNGHPLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 LAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAA
: .:. :. . :: :.. :: : :. ..:. . :. :
NP_000 --H-HWV-TSLSDGGPWSSTLATSPLDQQDVKPGREDLQLGA------IIHHRSPHV--A
60 70 80 90 100
130 140 150 160 170 180
pF1KB9 WAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGL
. : : . . ::.:. : . :::..:.: :: ..::: :: :.
NP_000 HHSPHTNHPNAWGASPAPNPSITSSGQPLNVYSQ---PG---FTVSGMLEHGGLTPPPAA
110 120 130 140 150
190 200 210 220 230 240
pF1KB9 HHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDE
: .. : . :: .::.: : . .::::
NP_000 ASA--QSLHPVLREPPDHGELGSH-HCQ---------------------------DHSDE
160 170 180
250 260 270 280 290 300
pF1KB9 DAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMC
..:.::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMC
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB9 KLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAH
::::::::::::.:::.::::..::::::::::::::::::.:::.::.::::::::.:.
NP_000 KLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQ
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB9 EITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPP
::..:::::::::::::::::::::::::::: : .: .::.
NP_000 EISSLADSLQLEKEVVRVWFCNRRQKEKRMTPP-GDQQP--HEVYSHTVKTDTSCHDL
310 320 330 340 350 360
430 440 450
pF1KB9 SAPPPPPPAALHHHHHHTLPGSVQ
>>XP_011541044 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 705 init1: 383 opt: 701 Z-score: 434.3 bits: 89.4 E(85289): 1.9e-17
Smith-Waterman score: 707; 49.1% identity (67.6% similar) in 275 aa overlap (184-450:109-346)
160 170 180 190 200 210
pF1KB9 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH
:::: : . :: . : ::: : :
XP_011 LSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGL--ASQAFGHPGLPGSSLEPHLEASQH
80 90 100 110 120 130
220 230 240 250 260 270
pF1KB9 AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSS-DDLEQFAKQFKQRRIKLGFT
. :: :..::. : ::. ..::.::: :::::::::::
XP_011 L----------PVPKHL-PSSGGA----------DEPSDLEELEKFAKTFKQRRIKLGFT
140 150 160 170
280 290 300 310 320
pF1KB9 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE-----TDSSSGSP
:.:::::.: :::: :::::: :::::.:::::::::::::.:::.. .: : ..:
XP_011 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTP
180 190 200 210 220 230
330 340 350 360 370 380
pF1KB9 TNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVW
.. ... :::::::::::.... .::..: ::::..::. .:..:..::::::::
XP_011 SSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVW
240 250 260 270 280 290
390 400 410 420 430 440
pF1KB9 FCNRRQKEKRMT-PAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHT
::::::::::.. :.: .:: :: ..:.:. .: :.:: : :
XP_011 FCNRRQKEKRINCPVATPIKPP---VYNSRLVSPSGS-LGPLSVPPV----------HST
300 310 320 330 340
450
pF1KB9 LPGSVQ
.::.:
XP_011 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTY
350 360 370 380 390 400
>>XP_011541045 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 705 init1: 383 opt: 701 Z-score: 434.3 bits: 89.4 E(85289): 1.9e-17
Smith-Waterman score: 707; 49.1% identity (67.6% similar) in 275 aa overlap (184-450:109-346)
160 170 180 190 200 210
pF1KB9 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH
:::: : . :: . : ::: : :
XP_011 LSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGL--ASQAFGHPGLPGSSLEPHLEASQH
80 90 100 110 120 130
220 230 240 250 260 270
pF1KB9 AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSS-DDLEQFAKQFKQRRIKLGFT
. :: :..::. : ::. ..::.::: :::::::::::
XP_011 L----------PVPKHL-PSSGGA----------DEPSDLEELEKFAKTFKQRRIKLGFT
140 150 160 170
280 290 300 310 320
pF1KB9 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE-----TDSSSGSP
:.:::::.: :::: :::::: :::::.:::::::::::::.:::.. .: : ..:
XP_011 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTP
180 190 200 210 220 230
330 340 350 360 370 380
pF1KB9 TNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVW
.. ... :::::::::::.... .::..: ::::..::. .:..:..::::::::
XP_011 SSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVW
240 250 260 270 280 290
390 400 410 420 430 440
pF1KB9 FCNRRQKEKRMT-PAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHT
::::::::::.. :.: .:: :: ..:.:. .: :.:: : :
XP_011 FCNRRQKEKRINCPVATPIKPP---VYNSRLVSPSGS-LGPLSVPPV----------HST
300 310 320 330 340
450
pF1KB9 LPGSVQ
.::.:
XP_011 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTY
350 360 370 380 390 400
>>XP_011541043 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 705 init1: 383 opt: 701 Z-score: 434.3 bits: 89.4 E(85289): 1.9e-17
Smith-Waterman score: 707; 49.1% identity (67.6% similar) in 275 aa overlap (184-450:109-346)
160 170 180 190 200 210
pF1KB9 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH
:::: : . :: . : ::: : :
XP_011 LSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGL--ASQAFGHPGLPGSSLEPHLEASQH
80 90 100 110 120 130
220 230 240 250 260 270
pF1KB9 AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSS-DDLEQFAKQFKQRRIKLGFT
. :: :..::. : ::. ..::.::: :::::::::::
XP_011 L----------PVPKHL-PSSGGA----------DEPSDLEELEKFAKTFKQRRIKLGFT
140 150 160 170
280 290 300 310 320
pF1KB9 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE-----TDSSSGSP
:.:::::.: :::: :::::: :::::.:::::::::::::.:::.. .: : ..:
XP_011 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTP
180 190 200 210 220 230
330 340 350 360 370 380
pF1KB9 TNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVW
.. ... :::::::::::.... .::..: ::::..::. .:..:..::::::::
XP_011 SSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVW
240 250 260 270 280 290
390 400 410 420 430 440
pF1KB9 FCNRRQKEKRMT-PAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHT
::::::::::.. :.: .:: :: ..:.:. .: :.:: : :
XP_011 FCNRRQKEKRINCPVATPIKPP---VYNSRLVSPSGS-LGPLSVPPV----------HST
300 310 320 330 340
450
pF1KB9 LPGSVQ
.::.:
XP_011 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTY
350 360 370 380 390 400
>>XP_011541041 (OMIM: 607394) PREDICTED: POU domain, cla (432 aa)
initn: 705 init1: 383 opt: 701 Z-score: 433.9 bits: 89.4 E(85289): 2e-17
Smith-Waterman score: 707; 49.1% identity (67.6% similar) in 275 aa overlap (184-450:138-375)
160 170 180 190 200 210
pF1KB9 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH
:::: : . :: . : ::: : :
XP_011 LSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGL--ASQAFGHPGLPGSSLEPHLEASQH
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSS-DDLEQFAKQFKQRRIKLGFT
. :: :..::. : ::. ..::.::: :::::::::::
XP_011 L----------PVPKHL-PSSGGA----------DEPSDLEELEKFAKTFKQRRIKLGFT
170 180 190 200
280 290 300 310 320
pF1KB9 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE-----TDSSSGSP
:.:::::.: :::: :::::: :::::.:::::::::::::.:::.. .: : ..:
XP_011 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTP
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB9 TNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVW
.. ... :::::::::::.... .::..: ::::..::. .:..:..::::::::
XP_011 SSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVW
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB9 FCNRRQKEKRMT-PAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHT
::::::::::.. :.: .:: :: ..:.:. .: :.:: : :
XP_011 FCNRRQKEKRINCPVATPIKPP---VYNSRLVSPSGS-LGPLSVPPV----------HST
330 340 350 360 370
450
pF1KB9 LPGSVQ
.::.:
XP_011 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTY
380 390 400 410 420 430
>>XP_011541042 (OMIM: 607394) PREDICTED: POU domain, cla (432 aa)
initn: 705 init1: 383 opt: 701 Z-score: 433.9 bits: 89.4 E(85289): 2e-17
Smith-Waterman score: 707; 49.1% identity (67.6% similar) in 275 aa overlap (184-450:138-375)
160 170 180 190 200 210
pF1KB9 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH
:::: : . :: . : ::: : :
XP_011 LSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGL--ASQAFGHPGLPGSSLEPHLEASQH
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSS-DDLEQFAKQFKQRRIKLGFT
. :: :..::. : ::. ..::.::: :::::::::::
XP_011 L----------PVPKHL-PSSGGA----------DEPSDLEELEKFAKTFKQRRIKLGFT
170 180 190 200
280 290 300 310 320
pF1KB9 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE-----TDSSSGSP
:.:::::.: :::: :::::: :::::.:::::::::::::.:::.. .: : ..:
XP_011 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTP
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB9 TNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVW
.. ... :::::::::::.... .::..: ::::..::. .:..:..::::::::
XP_011 SSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVW
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB9 FCNRRQKEKRMT-PAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHT
::::::::::.. :.: .:: :: ..:.:. .: :.:: : :
XP_011 FCNRRQKEKRINCPVATPIKPP---VYNSRLVSPSGS-LGPLSVPPV----------HST
330 340 350 360 370
450
pF1KB9 LPGSVQ
.::.:
XP_011 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTY
380 390 400 410 420 430
>>NP_055167 (OMIM: 607394) POU domain, class 2, transcri (436 aa)
initn: 705 init1: 383 opt: 701 Z-score: 433.9 bits: 89.4 E(85289): 2e-17
Smith-Waterman score: 707; 49.1% identity (67.6% similar) in 275 aa overlap (184-450:142-379)
160 170 180 190 200 210
pF1KB9 QPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGH
:::: : . :: . : ::: : :
NP_055 LSQTQPGQQGLQPNLLPFPQQQSGLLLPQTGPGL--ASQAFGHPGLPGSSLEPHLEASQH
120 130 140 150 160
220 230 240 250 260 270
pF1KB9 AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSS-DDLEQFAKQFKQRRIKLGFT
. :: :..::. : ::. ..::.::: :::::::::::
NP_055 L----------PVPKHL-PSSGGA----------DEPSDLEELEKFAKTFKQRRIKLGFT
170 180 190 200
280 290 300 310 320
pF1KB9 QADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEE-----TDSSSGSP
:.:::::.: :::: :::::: :::::.:::::::::::::.:::.. .: : ..:
NP_055 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTP
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB9 TNLDKIAAQ-GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVW
.. ... :::::::::::.... .::..: ::::..::. .:..:..::::::::
NP_055 SSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVW
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB9 FCNRRQKEKRMT-PAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHT
::::::::::.. :.: .:: :: ..:.:. .: :.:: : :
NP_055 FCNRRQKEKRINCPVATPIKPP---VYNSRLVSPSGS-LGPLSVPPV----------HST
330 340 350 360 370
450
pF1KB9 LPGSVQ
.::.:
NP_055 MPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHSTY
380 390 400 410 420 430
451 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:02:58 2016 done: Mon Nov 7 17:02:59 2016
Total Scan time: 10.230 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]