Result of FASTA (omim) for
pFN21AB8927
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8927, 273 aa
1>>>pF1KB8927 273 - 273 aa - 273 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6357+/-0.000321; mu= 7.0794+/- 0.020
mean_var=209.6442+/-41.391, 0's: 0 Z-trim(123.3): 230 B-trim: 33 in 1/57
Lambda= 0.088579
statistics sampled from 42751 (43005) to 42751 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.504), width: 16
Scan time: 8.920
The best scores are: opt bits E(85289)
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 1882 252.1 8e-67
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 1882 252.1 8e-67
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 495 75.0 2.2e-13
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 468 71.5 2.3e-12
NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 373 59.3 9.2e-09
NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 308 51.0 3e-06
NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 290 48.7 1.4e-05
NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 291 48.9 1.5e-05
XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 290 48.8 1.6e-05
NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 288 48.5 1.8e-05
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 282 47.6 2.6e-05
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 283 47.8 2.8e-05
NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 278 47.3 4.9e-05
NP_005915 (OMIM: 600535) homeobox protein MOX-2 [H ( 304) 276 46.9 5.2e-05
NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 272 46.5 7.8e-05
NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 268 46.0 0.00011
NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 265 45.7 0.00016
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 261 44.9 0.00017
NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 263 45.4 0.00019
XP_006723629 (OMIM: 604612) PREDICTED: homeobox pr ( 202) 257 44.3 0.00021
NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 254 43.8 0.00024
NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 ( 273) 257 44.5 0.00026
NP_796374 (OMIM: 605955) homeobox protein Nkx-6.2 ( 277) 257 44.5 0.00026
XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 256 44.3 0.00028
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 257 44.6 0.00031
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 255 44.3 0.00035
NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 253 43.9 0.00035
NP_005211 (OMIM: 104510,190320,600525) homeobox pr ( 287) 254 44.1 0.00035
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 44.7 0.00036
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 44.7 0.00036
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 44.7 0.00036
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 257 44.7 0.00036
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 44.7 0.00036
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 257 44.7 0.00036
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 257 44.7 0.00036
NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 252 43.8 0.00036
XP_016872278 (OMIM: 605955) PREDICTED: homeobox pr ( 277) 252 43.8 0.00041
NP_064448 (OMIM: 605211) barH-like 1 homeobox prot ( 327) 253 44.0 0.00042
XP_016867454 (OMIM: 603354) PREDICTED: homeobox pr ( 203) 247 43.1 0.00052
NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 249 43.4 0.00052
NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 249 43.4 0.00052
XP_016867453 (OMIM: 603354) PREDICTED: homeobox pr ( 204) 247 43.1 0.00052
NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 247 43.1 0.00058
NP_004088 (OMIM: 600034) homeobox protein EMX1 [Ho ( 290) 247 43.2 0.00066
NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 245 42.9 0.00075
NP_001092304 (OMIM: 603354) homeobox protein GBX-1 ( 363) 247 43.3 0.00077
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 243 42.9 0.0012
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 243 42.9 0.0012
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 243 42.9 0.0012
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 243 42.9 0.0012
>>NP_005510 (OMIM: 600647) homeobox protein HMX2 [Homo s (273 aa)
initn: 1882 init1: 1882 opt: 1882 Z-score: 1320.7 bits: 252.1 E(85289): 8e-67
Smith-Waterman score: 1882; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273)
10 20 30 40 50 60
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV
190 200 210 220 230 240
250 260 270
pF1KB8 PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
:::::::::::::::::::::::::::::::::
NP_005 PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
250 260 270
>>XP_005269800 (OMIM: 600647) PREDICTED: homeobox protei (273 aa)
initn: 1882 init1: 1882 opt: 1882 Z-score: 1320.7 bits: 252.1 E(85289): 8e-67
Smith-Waterman score: 1882; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273)
10 20 30 40 50 60
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRV
190 200 210 220 230 240
250 260 270
pF1KB8 PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
:::::::::::::::::::::::::::::::::
XP_005 PVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
250 260 270
>>NP_001099044 (OMIM: 613380) homeobox protein HMX3 [Hom (357 aa)
initn: 543 init1: 455 opt: 495 Z-score: 361.3 bits: 75.0 E(85289): 2.2e-13
Smith-Waterman score: 555; 41.2% identity (62.2% similar) in 291 aa overlap (7-264:72-353)
10 20 30
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPRE
:.:: : :...:..... : ::
NP_001 HRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKG--ALEGAAGFALSQV---GDLAFPRF
50 60 70 80 90
40 50 60 70 80 90
pF1KB8 PVGWPARKRSLSVSSEEEEPDDGWKAPACFCP-DQHGPK-EQGPKHHPPIPFPCLGTPKG
. ::.. .: . :. : .: : . : : :. : . : : :: .
NP_001 EI--PAQRFALPAHYLERSP--AWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRD
100 110 120 130 140 150
100 110 120 130
pF1KB8 SG----GSGPGGLE---RTP---FLSPSHSDFKEEKERLLP--------AGSPSPGSERP
: . : : ..: .: : :. .... . : :.. .::.:
NP_001 SPEPLLKADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAEDW
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB8 RDGGA--ERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVK
. :. :.. . :::::::::::::.:::::::::::::::::: ::.::.:::::::
NP_001 KKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVK
220 230 240 250 260 270
200 210 220 230 240
pF1KB8 TWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLR--------VPVPRS-
:::::::::::::.:::::::..::.:: .: .:......: . .::: :
NP_001 IWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQ
280 290 300 310 320 330
250 260 270
pF1KB8 --LAFPAPLYYPGSNLSALPLYNLYNKLDY
:.:: :.:: .:..::
NP_001 PLLTFPHPVYYSHPVVSSVPLLRPV
340 350
>>NP_061815 (OMIM: 142992,612109) homeobox protein HMX1 (348 aa)
initn: 466 init1: 440 opt: 468 Z-score: 342.8 bits: 71.5 E(85289): 2.3e-12
Smith-Waterman score: 485; 39.4% identity (56.6% similar) in 279 aa overlap (34-273:52-326)
10 20 30 40 50 60
pF1KB8 KEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEE---PDDGW
:.. . ::.: :. . :
NP_061 ENLLAAEAKGAGRATQGDGSREDEEEDDDDPEDEDAEQARRRRLQRRRQLLAGTGPGGEA
30 40 50 60 70 80
70 80 90 100 110
pF1KB8 KAPACFCPDQHG--PKEQGPKHHPPIPFPCLGT----PKGSGGSGPGGL--ERTPFLSPS
.: : . : : :. : ::. . : :. :.. :: : ::: . . ::
NP_061 RARALLGPGALGLGPRPP-PGPGPPFALGCGGAARWYPRAHGGYG-GGLSPDTSDRDSPE
90 100 110 120 130
120 130 140
pF1KB8 HSDFKEEKERLLPAGSPSPGS------------------------ERPRDGGAERQA---
.. . : : : :.::. : : .: : .
NP_061 TGEEMGRAEGAWPRG-PGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGV
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB8 -GAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKW
:. :::::::::::::.:::::::.::::::.::: ::.:::::::::: :::::::::
NP_061 GGGRKKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKW
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB8 KRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPL
::::.::::::... .:: :: .:.....: . . ..: :: :.. ::
NP_061 KRQLAAELEAASLSPPGAQRLVRVPVLYHESPPAAAAAGPPATLPFPLA-PAAPAPPPPL
260 270 280 290 300 310
270
pF1KB8 YNLYNKLDY
.. . : :
NP_061 LGFSGALAYPLAAFPAAASVPFLRAQMPGLV
320 330 340
>>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa)
initn: 376 init1: 267 opt: 373 Z-score: 278.3 bits: 59.3 E(85289): 9.2e-09
Smith-Waterman score: 374; 36.0% identity (55.2% similar) in 261 aa overlap (19-262:18-262)
10 20 30 40 50 60
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
:: :..::.: :. : : . :. . .:. . :.
NP_057 MEPGMLGPHNLPHHEPISFGIDQILSG-----PETPGGGLGLGRGGQGHGENGAFSGGY
10 20 30 40 50
70 80 90 100
pF1KB8 KAPACF--------CPDQHGPKEQG----PKHHP-PIPFPCLGTPKGSGGSGPGGLERTP
.. . . : . : : : :.: :.: : :.: : :: ::
NP_057 HGASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 FLS-P-SHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLE
:. : : . :.:: : :: :..: .: .:: :: :::::: .::
NP_057 GLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTP-PKRKKPRTSFSRSQVLELE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 STFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTL
: ..::.:.::: ::..:..:..::::::::::.::.:: . : :: : ... :
NP_057 RRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAER--HRAGRLL
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 VSMPLVFRDS--SLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
. . .:. :: :.: : :: .:.: ::
NP_057 LHLQ---QDALPRPLRPPLP-----PDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASV
240 250 260 270 280
NP_057 V
>>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa)
initn: 294 init1: 266 opt: 308 Z-score: 233.3 bits: 51.0 E(85289): 3e-06
Smith-Waterman score: 308; 32.8% identity (56.3% similar) in 247 aa overlap (24-262:42-271)
10 20 30 40 50
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEE
: ::: :. : . .:. :.. .
NP_066 PHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRP--GATYPSLPASFAGLGAP
20 30 40 50 60
60 70 80 90 100
pF1KB8 EEPDDGWKAPACFCPDQHGPKEQGPKHHP-----PIPFPCL--GTPKGSGGSGPGGLERT
: .... . : . . : :.: : :.: . :. :. :::.
NP_066 FEDAGSYSVNLSLAP---AGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN-F
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 PFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGA-ERQAGAAKKKTRTVFSRSQVYQLE
:.. :. . :.:. :.. .: . : : . .. .:: :: ::: :. .::
NP_066 PWMESSR---RFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 STFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTL
. : ..::.:.::: ::.::..:..::::::::::.::.:: . : :: . .:: :
NP_066 KRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQ-QASRLML
190 200 210 220 230 240
230 240 250 260 270
pF1KB8 VSMPLVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
. .:. : . :. : :: .:.: ::
NP_066 QLQHDAFQKS------LNDSIQ-PDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
250 260 270 280 290
>>NP_002440 (OMIM: 123101,168500,168550,604757) homeobox (267 aa)
initn: 292 init1: 237 opt: 290 Z-score: 221.3 bits: 48.7 E(85289): 1.4e-05
Smith-Waterman score: 290; 34.9% identity (54.5% similar) in 255 aa overlap (29-269:23-265)
10 20 30 40 50 60
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
::. .: : :..: ..::: : .
NP_002 MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEG-AAEERRVKVSSL---P---F
10 20 30 40
70 80 90 100 110
pF1KB8 KAPACFCPDQHGPKEQGPKHHPPIPFPCLGTPKGSGGSG------PGGLERTPFLSPS-H
.. : . :.. ::: .: : .: : :: : . :: . : .
NP_002 SVEA-LMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVK-PFETASVK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 SDFKEEKERLL--PAG-SPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDM
:. .:. . :. :: : : ... ...: :: :. ::. :: : .
NP_002 SENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKH--KTNRKPRTPFTTSQLLALERKFRQ
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 KRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQTLVSMPL
:.::: .::: ..:::.::::::: :::::: : :: :::: .:: :. . :. :
NP_002 KQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMA-AKPMLPSSFSL
170 180 190 200 210 220
240 250 260 270
pF1KB8 VFRDSSLLRVPVPRSLAFP--AP-LYYPGSNLSALPL-YNLYNKLDY
: :: :.. . ..: : : : .: : :. :..:.
NP_002 PFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS
230 240 250 260
>>NP_001180 (OMIM: 602183,613330) homeobox protein Nkx-3 (333 aa)
initn: 325 init1: 242 opt: 291 Z-score: 220.8 bits: 48.9 E(85289): 1.5e-05
Smith-Waterman score: 306; 31.3% identity (54.3% similar) in 265 aa overlap (1-255:97-314)
10 20 30
pF1KB8 MGSKEDAGKGCPAAGGVSSFTIQSILGGGP
.. .... . : : :.:. .. ::.
NP_001 EDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASG---AGLAGGSL
70 80 90 100 110 120
40 50 60 70 80
pF1KB8 SEAPREPVGWPARKRSLSVSSEEEEPDDGWKAPACFCPDQHGPKEQ----GPKHHPPIPF
: .: :. . . : . ::: . . . ...:. . ::. .
NP_001 S------LGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRG-AHVSA
130 140 150 160 170
90 100 110 120 130 140
pF1KB8 PCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAG
: :. :.:::::.:. .::.: :.. .::
NP_001 LCSGAG-GGGGSGPAGVA------------EEEEE---------PAAPKPR---------
180 190 200
150 160 170 180 190 200
pF1KB8 AAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKR
::..:..::..::..:: :. .::::. ::: ::.::.::::::: :::::: : ::
NP_001 --KKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB8 -QLSAELEAANMAHASAQTLVSMPLVFRDSSLLRVP-----VPRSLAFPAPLYYPGSNLS
:..:.: .: : : :.. .. ::.. .: : : . :::
NP_001 RQMAADL----LASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYPYYCLP
270 280 290 300 310
270
pF1KB8 ALPLYNLYNKLDY
NP_001 GWALSTCAAAAGTQ
320 330
>>XP_011538046 (OMIM: 186770) PREDICTED: T-cell leukemia (342 aa)
initn: 353 init1: 261 opt: 290 Z-score: 220.0 bits: 48.8 E(85289): 1.6e-05
Smith-Waterman score: 314; 32.7% identity (55.4% similar) in 269 aa overlap (2-262:75-318)
10 20
pF1KB8 MGSKEDAGKGCPAAGG--------VSSFTIQ
:. .: : ::.:: ..:....
XP_011 YGLGCLVGGAYTYGGGGSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVN
50 60 70 80 90 100
30 40 50 60 70 80
pF1KB8 SILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGWKAPACFCPDQHGPKEQGPKHHPP
:.:::. : : . .::... . : : : :. : : :
XP_011 MALAGGPG--PGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQ---PLATG---LPT
110 120 130 140 150
90 100 110 120 130 140
pF1KB8 IPFPCLGTPKGSGGSGPGGLERTPFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAER
.: ..: : .. :: :.. .:. . :.:. : :: ..: .:
XP_011 VP----SVPAMPGVNNLTGLT-FPWM---ESNRRYTKDRFTVALSPFTVTRRIGHPYQNR
160 170 180 190 200
150 160 170 180 190 200
pF1KB8 QAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNK
::: :: :.: :. .::. : ..::.:.::: ::..:..:..::::::::::.:
XP_011 TP-PKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTK
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB8 WKRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFPAPLYYPGSNLSALP
:.:: .:: . :. .:. : . .:. : : :.: . :: .:.: ::
XP_011 WRRQ-TAEEREAERQQANRILLQLQQEAFQKS--LAQPLPAD-----PLCVHNSSLFALQ
270 280 290 300 310
270
pF1KB8 LYNLYNKLDY
XP_011 NLQPWSDDSTKITSVTSVASACE
320 330 340
>>NP_001129743 (OMIM: 217095,611770) homeobox protein Nk (301 aa)
initn: 311 init1: 225 opt: 288 Z-score: 219.3 bits: 48.5 E(85289): 1.8e-05
Smith-Waterman score: 308; 35.2% identity (57.3% similar) in 213 aa overlap (67-251:25-233)
40 50 60 70 80 90
pF1KB8 PVGWPARKRSLSVSSEEEEPDDGWKAPACFCP--DQHGPKEQGPKHHPPIPFPCLGTPKG
:: . : ...:.. . . . :.:
NP_001 MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMD--AEPRG
10 20 30 40 50
100 110 120 130
pF1KB8 S--GGSGPGGLERT-----PFLSPSHSDFKEEKERL------LPAGSPSPGSER-P----
: ..: :: .: : .: .. .. . ::. : :.:: :. : :
NP_001 SEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGV
60 70 80 90 100 110
140 150 160 170 180
pF1KB8 -------RDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLT
: : .:. . ..: :..::..:: :: : ..::::. :: :::.::::
NP_001 GNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 ETQVKTWFQNRRNKWKRQLSAE-LEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAF
:::: :::::: : ::: . . :: :. : . :..:.. ::.. : : . ::
NP_001 STQVKIWFQNRRYKCKRQRQDKSLELAG--HPLTPRRVAVPVLVRDGKPCLGPGPGAPAF
180 190 200 210 220 230
250 260 270
pF1KB8 PAPLYYPGSNLSALPLYNLYNKLDY
:.:
NP_001 PSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGH
240 250 260 270 280 290
273 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:59:14 2016 done: Sun Nov 6 04:59:16 2016
Total Scan time: 8.920 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]