Result of FASTA (omim) for
pFN21AB8520
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8520, 874 aa
1>>>pF1KB8520 874 - 874 aa - 874 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2030+/-0.000363; mu= 4.9544+/- 0.023
mean_var=219.9856+/-44.759, 0's: 0 Z-trim(120.9): 3 B-trim: 0 in 0/58
Lambda= 0.086472
statistics sampled from 36797 (36802) to 36797 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.431), width: 16
Scan time: 13.010
The best scores are: opt bits E(85289)
NP_060988 (OMIM: 609357) protein MCM10 homolog iso ( 874) 5744 729.8 1.3e-209
XP_011517840 (OMIM: 609357) PREDICTED: protein MCM ( 875) 5732 728.3 3.8e-209
NP_877428 (OMIM: 609357) protein MCM10 homolog iso ( 875) 5732 728.3 3.8e-209
>>NP_060988 (OMIM: 609357) protein MCM10 homolog isoform (874 aa)
initn: 5744 init1: 5744 opt: 5744 Z-score: 3883.9 bits: 729.8 E(85289): 1.3e-209
Smith-Waterman score: 5744; 100.0% identity (100.0% similar) in 874 aa overlap (1-874:1-874)
10 20 30 40 50 60
pF1KB8 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NLQEQMKALQEQLKVTTIKQTASPARLQKSPEKSPRPPLKERRVQRIQESTCFSAELDVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGET
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVIL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMKP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQYK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 KLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 KIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKAT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 QPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 AITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRRE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 QLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 TCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKW
790 800 810 820 830 840
850 860 870
pF1KB8 ERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
::::::::::::::::::::::::::::::::::
NP_060 ERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
850 860 870
>>XP_011517840 (OMIM: 609357) PREDICTED: protein MCM10 h (875 aa)
initn: 4779 init1: 4779 opt: 5732 Z-score: 3875.8 bits: 728.3 E(85289): 3.8e-209
Smith-Waterman score: 5732; 99.9% identity (99.9% similar) in 875 aa overlap (1-874:1-875)
10 20 30 40 50 60
pF1KB8 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 NLQEQMKALQEQLKVTTIKQTASPARLQKSP-EKSPRPPLKERRVQRIQESTCFSAELDV
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
790 800 810 820 830 840
840 850 860 870
pF1KB8 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
:::::::::::::::::::::::::::::::::::
XP_011 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
850 860 870
>>NP_877428 (OMIM: 609357) protein MCM10 homolog isoform (875 aa)
initn: 4779 init1: 4779 opt: 5732 Z-score: 3875.8 bits: 728.3 E(85289): 3.8e-209
Smith-Waterman score: 5732; 99.9% identity (99.9% similar) in 875 aa overlap (1-874:1-875)
10 20 30 40 50 60
pF1KB8 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MDEEEDNLSLLTALLEENESALDCNSEENNFLTRENGEPDAFDELFDADGDGESYTEEAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 DGETGETRDEKENLATLFGDMEDLTDEEEVPASQSTENRVLPAPAPRREKTNEELQEELR
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 NLQEQMKALQEQLKVTTIKQTASPARLQKSP-EKSPRPPLKERRVQRIQESTCFSAELDV
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_877 NLQEQMKALQEQLKVTTIKQTASPARLQKSPVEKSPRPPLKERRVQRIQESTCFSAELDV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 PALPRTKRVARTPKASPPDPKSSSSRMTSAPSQPLQTISRNKPSGITRGQIVGTPGSSGE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TTQPICVEAFSGLRLRRPRVSSTEMNKKMTGRKLIRLSQIKEKMAREKLEEIDWVTFGVI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 LKKVTPQSVNSGKTFSIWKLNDLRDLTQCVSLFLFGEVHKALWKTEQGTVVGILNANPMK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 PKDGSEEVCLSIDHPQKVLIMGEALDLGTCKAKKKNGEPCTQTVNLRDCEYCQYHVQAQY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 KKLSAKRADLQSTFSGGRIPKKFARRGTSLKERLCQDGFYYGGVSSASYAASIAAAVAPK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 KKIQTTLSNLVVKGTNLIIQETRQKLGIPQKSLSCSEEFKELMDLPTCGARNLKQHLAKA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 RQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 AAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRR
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 EQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 VTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYK
790 800 810 820 830 840
840 850 860 870
pF1KB8 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
:::::::::::::::::::::::::::::::::::
NP_877 WERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK
850 860 870
874 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:35:18 2016 done: Sun Nov 6 15:35:20 2016
Total Scan time: 13.010 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]