Result of FASTA (omim) for
pFN21AB8513
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8513, 943 aa
1>>>pF1KB8513 943 - 943 aa - 943 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0230+/-0.000357; mu= 0.5919+/- 0.022
mean_var=288.8212+/-59.476, 0's: 0 Z-trim(122.8): 59 B-trim: 344 in 1/58
Lambda= 0.075467
statistics sampled from 41388 (41458) to 41388 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.486), width: 16
Scan time: 16.910
The best scores are: opt bits E(85289)
NP_002212 (OMIM: 147522) inositol-trisphosphate 3- ( 946) 6416 712.6 2.3e-204
XP_016856700 (OMIM: 147522) PREDICTED: inositol-tr ( 730) 4382 491.1 8.5e-138
XP_005273177 (OMIM: 147522) PREDICTED: inositol-tr ( 644) 4367 489.4 2.4e-137
NP_002211 (OMIM: 147521) inositol-trisphosphate 3- ( 461) 1437 170.3 2e-41
NP_079470 (OMIM: 606476,611775) inositol-trisphosp ( 683) 1380 164.2 2e-39
XP_011519824 (OMIM: 147521) PREDICTED: inositol-tr ( 289) 1303 155.5 3.5e-37
XP_016882813 (OMIM: 606476,611775) PREDICTED: inos ( 422) 1212 145.8 4.5e-34
>>NP_002212 (OMIM: 147522) inositol-trisphosphate 3-kina (946 aa)
initn: 5820 init1: 5820 opt: 6416 Z-score: 3790.1 bits: 712.6 E(85289): 2.3e-204
Smith-Waterman score: 6416; 99.5% identity (99.6% similar) in 946 aa overlap (1-943:1-946)
10 20 30 40 50 60
pF1KB8 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSS---VSSPSWAGRLRGDRQQVVAAGTLS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_002 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDALSWSRLPRALAS
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_002 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 ALPSPELLPQDQDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAF
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB8 REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 REFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGK
850 860 870 880 890 900
900 910 920 930 940
pF1KB8 TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMSQDAPLA
910 920 930 940
>>XP_016856700 (OMIM: 147522) PREDICTED: inositol-trisph (730 aa)
initn: 4432 init1: 3769 opt: 4382 Z-score: 2594.8 bits: 491.1 E(85289): 8.5e-138
Smith-Waterman score: 4382; 97.7% identity (98.3% similar) in 657 aa overlap (1-654:1-657)
10 20 30 40 50 60
pF1KB8 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSS---VSSPSWAGRLRGDRQQVVAAGTLS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDALSWSRLPRALAS
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 ALPSPELLPQDQDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
:::::::::::::::::::::::::::::::::::::::::::: .: . :.:
XP_016 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVVESRSVTQAGVQWHDI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
XP_016 GSLQPLPPGFKQFSRLSLPNSWDYRRMPPCPDNFCIFSRNGFSPCWPGWSLSLDLVILPS
670 680 690 700 710 720
>>XP_005273177 (OMIM: 147522) PREDICTED: inositol-trisph (644 aa)
initn: 3771 init1: 3771 opt: 4367 Z-score: 2586.8 bits: 489.4 E(85289): 2.4e-137
Smith-Waterman score: 4367; 99.2% identity (99.4% similar) in 644 aa overlap (1-641:1-644)
10 20 30 40 50 60
pF1KB8 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVYCYALNSLVIMNSANEMKSGGGPGPSGSETPPPPRRAVLSPGSVFSPGRGASFLFPP
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSS---VSSPSWAGRLRGDRQQVVAAGTLS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_005 AESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGTLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPGPEEAKRKLRILQRELQNVQVNQKVGMFEAHIQAQSSAIQAPRSPRLGRARSPSPCPF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMPPLPGR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAPTGSEAQGPSAFVRMEKGIPASPRCGSPTAMEIDKRGSPTPGTRSCLAPSLGLFGASL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGSETSPAPER
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDALSWSRLPRALAS
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_005 GGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAESSDSLSWSRLPRALAS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGPEEARSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGIPSGRMLEPLP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEGTWESQRQDSD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 ALPSPELLPQDQDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALPSPELLPQDPDKPFLRKACSPSNIPAVIITDMGTQEDGALEETQGSPRGNLPLRKLSS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPF
::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRV
610 620 630 640
660 670 680 690 700 710
pF1KB8 VMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVV
>>NP_002211 (OMIM: 147521) inositol-trisphosphate 3-kina (461 aa)
initn: 1400 init1: 1189 opt: 1437 Z-score: 864.7 bits: 170.3 E(85289): 2e-41
Smith-Waterman score: 1437; 57.0% identity (76.2% similar) in 400 aa overlap (542-938:67-460)
520 530 540 550 560 570
pF1KB8 KAGLAWTRGTGVQSEGTWESQRQDSDALPSPELLPQDQDKPFLRKACSPSNIPAVIITDM
:. ::. : . . .. : : :.
NP_002 LFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSP
40 50 60 70 80 90
580 590 600 610 620 630
pF1KB8 GTQE-DGALEETQGSPRGNLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAF
: : . . :: . . : :.::.::.:::: :: ::::.:. :: : : .
NP_002 GPPERERDCLPAAGSSHLQQP-RRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQL
100 110 120 130 140 150
640 650 660 670 680
pF1KB8 LHTLD-QQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAA-NGRILKK
: :: . :.::..::. : . :::.: :.:::::.::::::. .: :::.
NP_002 EAGEDVGQK----NHWQKIRTMVNL-PVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKR
160 170 180 190 200 210
690 700 710 720 730 740
pF1KB8 HCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTY
: :. :: :::.:.:: :::.:: : .::: : :..::: ::.:::.:::::.:::
NP_002 CSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTY
220 230 240 250 260 270
750 760 770 780 790 800
pF1KB8 LEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGF
:::::::::..:.::::::.::. ::::::::::.::::::::::::::: :::..::::
NP_002 LEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGF
280 290 300 310 320 330
810 820 830 840 850 860
pF1KB8 RIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFF
::::::: ::. . ::: :..:::: ..:.::..:....: : .::. :: ::::: ::
NP_002 RIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFF
340 350 360 370 380 390
870 880 890 900 910 920
pF1KB8 KCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNN
. ::::::::::.::. ..: ::.::::::::::.:: :.: ::.::::::::: ::.:
NP_002 RRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDN
400 410 420 430 440 450
930 940
pF1KB8 LVDILTEMSQDAPLA
:. ::. ...
NP_002 LIGILASLAER
460
>>NP_079470 (OMIM: 606476,611775) inositol-trisphosphate (683 aa)
initn: 1434 init1: 1356 opt: 1380 Z-score: 828.8 bits: 164.2 E(85289): 2e-39
Smith-Waterman score: 1462; 39.0% identity (61.5% similar) in 751 aa overlap (205-938:3-682)
180 190 200 210 220 230
pF1KB8 CPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSGRKGGPSLCSSQVKKGMP-P
.:: .. . .. :. . .. :. :
NP_079 MRRCPCRGSLNEAEAGA---LPAAARMGLEAP
10 20
240 250 260 270 280
pF1KB8 LPGRAAPTGSEAQGPSAFV---RMEKGIPASPRCGSPTAMEIDKRG-SPTPGTRSCLAPS
:: :.. ::.: . : : : : . :: : .. : .:.:::.: :.
NP_079 RGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSLHSEPERAGLGPAPGTES---PQ
30 40 50 60 70 80
290 300 310 320 330 340
pF1KB8 LGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQGQFLGS
.. . :: :: .. .::.. :::. :. :. . : . : .
NP_079 AEFWTDG---QTEPAAAGLGVETERPKQK--TEPD-RSSLRTHLE--WSWSELETTCLWT
90 100 110 120 130
350 360 370 380 390 400
pF1KB8 ETSPAPERGGPRDGEPPGKMGKGYLPCGMPGSGEPEVGKRPEETTVSVQSAES-SDALSW
::. :. .. . .. : .:: : . . . . .. . ..: .: : :
NP_079 ETGTDGLWTDPHRSDLQFQPEEAS-PWTQPGVHGPWTELETHGSQTQPERVKSWADNL-W
140 150 160 170 180 190
410 420 430 440 450 460
pF1KB8 SRLPRALASVGPEEA-RSGAPVGGGRWQLSDRVEGGSPTLGLLGGSPSAQPGTGNVEAGI
.. . .. :: : : : . : :. . :: : . : : ..: : . .
NP_079 THQNSSSLQTHPEGACPSKEPSADGSWK--ELYTDGSRTQQDIEG-PWTEPYTDGSQK--
200 210 220 230 240 250
470 480 490 500 510 520
pF1KB8 PSGRMLEPLPCWDAAKDLKEPQCPPGDRVGVQPGNSRVWQGTMEKAGLAWTRGTGVQSEG
.: . . :: :. .. : : : .::. . ..:
NP_079 --------------KQDTEAARKQPGT------GGFQIQQDT---DG-SWTQPS---TDG
260 270 280
530 540 550 560 570
pF1KB8 TWESQRQDSDALPSPELLPQDQDKP-------FLRKACSP-SNIPAVIITDMGTQEDGAL
. . : : :: : .. .: . . ::: .: .:::
NP_079 SQTAPGTDC-LLGEPEDGPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITP-------ET
290 300 310 320 330
580 590 600 610 620 630
pF1KB8 EETQGSPRGNLPLRKLSSSSASSTGFSS--SYEDSEEDISSDPERTLDPNSAFLHTLDQQ
: ...: : : .. ..:. :::: :...::.:. . . ::. :..
NP_079 PEPEAQPVG--PPSRVEGGSG---GFSSASSFDESEDDVVAGGGGASDPE-------DRS
340 350 360 370 380
640 650 660 670 680 690
pF1KB8 KPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCL
:: :.:.:.....::::.::.:.:::.::.::::.:.:. .:::::. :. ::: :
NP_079 G---SKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSL
390 400 410 420 430 440
700 710 720 730 740 750
pF1KB8 DRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKAR
..:: : ::::::::.: :..::. .:::.::::::..: .:::::: ::::::::.:::
NP_079 EQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKAR
450 460 470 480 490 500
760 770 780 790 800 810
pF1KB8 KKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKED
..: :::::.::. ::: ::: ::.:: :::::::::::::.:::.::::::::::: :
NP_079 ERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKAD
510 520 530 540 550 560
820 830 840 850 860 870
pF1KB8 GTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSS
:: : .::::.. ::::.....:. :.: :: : :. .: .::.::::: :::.:::
NP_079 GTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSS
570 580 590 600 610 620
880 890 900 910 920 930
pF1KB8 LLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDILTEMS
:::.::. :::::::::::. ::. :::.: .:: ::::::::: ::.:.. .: ..
NP_079 LLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMICLLQGLA
630 640 650 660 670 680
940
pF1KB8 QDAPLA
:
NP_079 QS
>>XP_011519824 (OMIM: 147521) PREDICTED: inositol-trisph (289 aa)
initn: 1318 init1: 1178 opt: 1303 Z-score: 788.6 bits: 155.5 E(85289): 3.5e-37
Smith-Waterman score: 1303; 66.2% identity (85.6% similar) in 284 aa overlap (656-938:5-288)
630 640 650 660 670 680
pF1KB8 PNSAFLHTLDQQKPRVSKSWRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGSFKAAA-NGR
: . :::.: :.:::::.::::::. .:
XP_011 MVNLPVISPFKKRYAWVQLAGHTGSFKAAGTSGL
10 20 30
690 700 710 720 730 740
pF1KB8 ILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCKMG
:::. : :. :: :::.:.:: :::.:: : .::: : :..::: ::.:::.:::::
XP_011 ILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMG
40 50 60 70 80 90
750 760 770 780 790 800
pF1KB8 IRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTA
.::::::::::::..:.::::::.::. ::::::::::.::::::::::::::: :::..
XP_011 VRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSST
100 110 120 130 140 150
810 820 830 840 850 860
pF1KB8 TLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEV
::::::::::: ::. . ::: :..:::: ..:.::..:....: : .::. :: ::::
XP_011 TLGFRIEGIKKADGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEV
160 170 180 190 200 210
870 880 890 900 910 920
pF1KB8 SPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLS
: ::. ::::::::::.::. ..: ::.::::::::::.:: :.: ::.:::::::::
XP_011 SEFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLL
220 230 240 250 260 270
930 940
pF1KB8 GLNNLVDILTEMSQDAPLA
::.::. ::. ...
XP_011 GLDNLIGILASLAER
280
>>XP_016882813 (OMIM: 606476,611775) PREDICTED: inositol (422 aa)
initn: 1330 init1: 1161 opt: 1212 Z-score: 732.8 bits: 145.8 E(85289): 4.5e-34
Smith-Waterman score: 1346; 53.0% identity (73.4% similar) in 406 aa overlap (558-938:38-421)
530 540 550 560 570 580
pF1KB8 TWESQRQDSDALPSPELLPQDQDKPFLRKACSP-SNIPAVIITDMGTQEDGALEETQGSP
::: .: .::: : ...:
XP_016 ILKQPGNSLALVVSKYNRILMAPGHNLALTCSPLCPVPRLIITP-------ETPEPEAQP
10 20 30 40 50 60
590 600 610 620 630 640
pF1KB8 RGNLPLRKLSSSSASSTGFSS--SYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKS
: : .. ..:. :::: :...::.:. . . ::. :.. ::
XP_016 VG--PPSRVEGGSG---GFSSASSFDESEDDVVAGGGGASDPE-------DRSG---SKP
70 80 90 100
650 660 670 680
pF1KB8 WRKIKNMVHWSPFVMSFKKKYPWIQLAGHAGS----------------------FKAAAN
:.:.:.....::::.::.:.:::.::.::::: :.:. .
XP_016 WKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGSCGEVLFLIQFLILSFILPPLGNFQAGED
110 120 130 140 150 160
690 700 710 720 730 740
pF1KB8 GRILKKHCESEQRCLDRLMVDVLRPFVPAYHGDVVKDGERYNQMDDLLADFDSPCVMDCK
:::::. :. ::: :..:: : ::::::::.: :..::. .:::.::::::..: .::::
XP_016 GRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGPSIMDCK
170 180 190 200 210 220
750 760 770 780 790 800
pF1KB8 MGIRTYLEEELTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISS
:: ::::::::.:::..: :::::.::. ::: ::: ::.:: :::::::::::::.::
XP_016 MGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSS
230 240 250 260 270 280
810 820 830 840 850 860
pF1KB8 TATLGFRIEGIKKEDGTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTL
:.::::::::::: ::: : .::::.. ::::.....:. :.: :: : :. .: .:
XP_016 TSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREAL
290 300 310 320 330 340
870 880 890 900 910 920
pF1KB8 EVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGY
:.::::: :::.::::::.::. :::::::::::. ::. :::.: .:: ::::::::
XP_016 EISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGY
350 360 370 380 390 400
930 940
pF1KB8 LSGLNNLVDILTEMSQDAPLA
: ::.:.. .: ..:
XP_016 LWGLDNMICLLQGLAQS
410 420
943 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:07:43 2016 done: Mon Nov 7 18:07:46 2016
Total Scan time: 16.910 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]