Result of FASTA (ccds) for
pFN21AB8401
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8401, 953 aa
1>>>pF1KB8401 953 - 953 aa - 953 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8013+/-0.00131; mu= 18.7332+/- 0.078
mean_var=72.2821+/-13.830, 0's: 0 Z-trim(100.4): 40 B-trim: 0 in 0/50
Lambda= 0.150855
statistics sampled from 6094 (6114) to 6094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.531), E-opt: 0.2 (0.188), width: 16
Scan time: 4.130
The best scores are: opt bits E(32554)
CCDS7815.1 COPB1 gene_id:1315|Hs108|chr11 ( 953) 6121 1342.5 0
CCDS32622.1 AP2B1 gene_id:163|Hs108|chr17 ( 937) 266 68.2 8.6e-11
CCDS32621.1 AP2B1 gene_id:163|Hs108|chr17 ( 951) 266 68.2 8.8e-11
>>CCDS7815.1 COPB1 gene_id:1315|Hs108|chr11 (953 aa)
initn: 6121 init1: 6121 opt: 6121 Z-score: 7193.8 bits: 1342.5 E(32554): 0
Smith-Waterman score: 6121; 100.0% identity (100.0% similar) in 953 aa overlap (1-953:1-953)
10 20 30 40 50 60
pF1KB8 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI
850 860 870 880 890 900
910 920 930 940 950
pF1KB8 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI
910 920 930 940 950
>>CCDS32622.1 AP2B1 gene_id:163|Hs108|chr17 (937 aa)
initn: 183 init1: 105 opt: 266 Z-score: 307.2 bits: 68.2 E(32554): 8.6e-11
Smith-Waterman score: 296; 19.8% identity (52.1% similar) in 606 aa overlap (26-604:18-577)
10 20 30 40 50 60
pF1KB8 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
:: .:.. ... ::.:::: . :. . .:.
CCDS32 MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFP
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
.. . .. .:::. .. :. :: :.. ... :: . :: .::. .
CCDS32 DVVN-CMQTDNLELKKLVYLYLMNYAKSQPD-----MAIMAVNSFVKDCEDPNPLIRALA
60 70 80 90 100
130 140 150 160 170
pF1KB8 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPEL--IH
.: . .. .. : : .: ::. . :::..:.. . .. ... : : ..
CCDS32 VRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 DFLVNEKDASCKRNAFMMLIHADQDRA----LDYLSTCIDQVQT-FGDILQLVIVELIYK
: :. ... :: : . .... :: :... : ... . . ..
CCDS32 D-LIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDC
170 180 190 200 210 220
240 250 260 270 280
pF1KB8 VCHANPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIK-----AAAQCYIDL
. . ::.. : .. . .: ... :.. :.::.. . .: . : ..
CCDS32 LSNYNPKDD----REAQSICERVTPRLSH--ANSAVVLSAVKVLMKFLELLPKDSDYYNM
230 240 250 260 270
290 300 310 320 330
pF1KB8 IIKE----------SDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRK
..:. .. .:. ..: : :.: . : . :.. .. : . . :.
CCDS32 LLKKLAPPLVTLLSGEPEVQYVAL-RNINLIVQKRPEILKQEI--KVFFVKYNDPIYVKL
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB8 KTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMA
. :.. . :.:. :. ... ::. . .. :.: :. ::.. :... . :
CCDS32 EKLDIMIRLASQANIAQVLAELKEYATEV-------DVDFVRKA-VRAIGRCAIKVEQSA
340 350 360 370 380
400 410 420 430 440 450
pF1KB8 ANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGA
. .:..... . . .. ... .:. .... : :. . : . .. .
CCDS32 ERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAM
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 LWILGEYCSTKEDIQSVMTEIRRSL-GEIPIVESEIKKEAGEL---KPEEEITVGPVQKL
.::.::: .. . .. . ... : :. . .: :: : .:.:
CCDS32 IWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSE------TQEL
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB8 VTEMGTYATQSALSSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQE
: .. . :::. :. : . :: . ::. : .: ...: :..:
CCDS32 VQQVLSLATQD---SDNPDLR--DRGYIYWRLLSTD-------PVTAKEVVLSEKPLISE
510 520 530 540 550
580 590 600 610 620 630
pF1KB8 KKKQNSFVAEAMLLMATILHLGK-SSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNK
. . : :: : :.:. .:. .::
CCDS32 ETD----LIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP
560 570 580 590 600
640 650 660 670 680 690
pF1KB8 ECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSL
CCDS32 VGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQ
610 620 630 640 650 660
>>CCDS32621.1 AP2B1 gene_id:163|Hs108|chr17 (951 aa)
initn: 183 init1: 105 opt: 266 Z-score: 307.1 bits: 68.2 E(32554): 8.8e-11
Smith-Waterman score: 296; 19.8% identity (52.1% similar) in 606 aa overlap (26-604:18-577)
10 20 30 40 50 60
pF1KB8 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
:: .:.. ... ::.:::: . :. . .:.
CCDS32 MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFP
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
.. . .. .:::. .. :. :: :.. ... :: . :: .::. .
CCDS32 DVVN-CMQTDNLELKKLVYLYLMNYAKSQPD-----MAIMAVNSFVKDCEDPNPLIRALA
60 70 80 90 100
130 140 150 160 170
pF1KB8 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPEL--IH
.: . .. .. : : .: ::. . :::..:.. . .. ... : : ..
CCDS32 VRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 DFLVNEKDASCKRNAFMMLIHADQDRA----LDYLSTCIDQVQT-FGDILQLVIVELIYK
: :. ... :: : . .... :: :... : ... . . ..
CCDS32 D-LIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDC
170 180 190 200 210 220
240 250 260 270 280
pF1KB8 VCHANPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIK-----AAAQCYIDL
. . ::.. : .. . .: ... :.. :.::.. . .: . : ..
CCDS32 LSNYNPKDD----REAQSICERVTPRLSH--ANSAVVLSAVKVLMKFLELLPKDSDYYNM
230 240 250 260 270
290 300 310 320 330
pF1KB8 IIKE----------SDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRK
..:. .. .:. ..: : :.: . : . :.. .. : . . :.
CCDS32 LLKKLAPPLVTLLSGEPEVQYVAL-RNINLIVQKRPEILKQEI--KVFFVKYNDPIYVKL
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB8 KTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMA
. :.. . :.:. :. ... ::. . .. :.: :. ::.. :... . :
CCDS32 EKLDIMIRLASQANIAQVLAELKEYATEV-------DVDFVRKA-VRAIGRCAIKVEQSA
340 350 360 370 380
400 410 420 430 440 450
pF1KB8 ANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGA
. .:..... . . .. ... .:. .... : :. . : . .. .
CCDS32 ERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAM
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 LWILGEYCSTKEDIQSVMTEIRRSL-GEIPIVESEIKKEAGEL---KPEEEITVGPVQKL
.::.::: .. . .. . ... : :. . .: :: : .:.:
CCDS32 IWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSE------TQEL
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB8 VTEMGTYATQSALSSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQE
: .. . :::. :. : . :: . ::. : .: ...: :..:
CCDS32 VQQVLSLATQD---SDNPDLR--DRGYIYWRLLSTD-------PVTAKEVVLSEKPLISE
510 520 530 540 550
580 590 600 610 620 630
pF1KB8 KKKQNSFVAEAMLLMATILHLGK-SSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNK
. . : :: : :.:. .:. .::
CCDS32 ETD----LIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSP
560 570 580 590 600
640 650 660 670 680 690
pF1KB8 ECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSL
CCDS32 VGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLLGS
610 620 630 640 650 660
953 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:17:13 2016 done: Sun Nov 6 22:17:14 2016
Total Scan time: 4.130 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]