Result of FASTA (ccds) for
pFN21AB8296
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8296, 422 aa
1>>>pF1KB8296 422 - 422 aa - 422 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7228+/-0.000856; mu= 7.2115+/- 0.051
mean_var=151.1530+/-29.856, 0's: 0 Z-trim(112.0): 20 B-trim: 36 in 1/51
Lambda= 0.104320
statistics sampled from 12849 (12866) to 12849 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.395), width: 16
Scan time: 2.680
The best scores are: opt bits E(32554)
CCDS6969.1 REXO4 gene_id:57109|Hs108|chr9 ( 422) 2796 432.3 4.2e-121
CCDS65179.1 REXO4 gene_id:57109|Hs108|chr9 ( 250) 782 129.0 4.9e-30
CCDS10344.1 AEN gene_id:64782|Hs108|chr15 ( 325) 515 88.9 7.5e-18
CCDS1153.1 ISG20L2 gene_id:81875|Hs108|chr1 ( 353) 458 80.4 3.1e-15
CCDS10345.1 ISG20 gene_id:3669|Hs108|chr15 ( 181) 389 69.8 2.4e-12
>>CCDS6969.1 REXO4 gene_id:57109|Hs108|chr9 (422 aa)
initn: 2796 init1: 2796 opt: 2796 Z-score: 2287.6 bits: 432.3 E(32554): 4.2e-121
Smith-Waterman score: 2796; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB8 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KAPEDFSQNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGEEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 KAPEDFSQNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGEEMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 AGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHKKRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 AKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 AKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 LKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 RPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 RPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDHCSD
370 380 390 400 410 420
pF1KB8 DA
::
CCDS69 DA
>>CCDS65179.1 REXO4 gene_id:57109|Hs108|chr9 (250 aa)
initn: 1277 init1: 778 opt: 782 Z-score: 652.7 bits: 129.0 E(32554): 4.9e-30
Smith-Waterman score: 990; 50.1% identity (53.9% similar) in 425 aa overlap (1-422:1-250)
10 20 30 40 50 60
pF1KB8 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPASGPGAVVRPP
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 KAPEDFSQNWKALQE---WLLKQKSQAPEKPLVISQMGSKKKPKIIQQNKKETSPQVKGE
::::::::::::::: : .. :: .: . : .:.:. ::.
CCDS65 KAPEDFSQNWKALQEVPRWTGGRQYLAP-RP--VEQSTIRKEPR-------------KGQ
70 80 90 100
120 130 140 150 160 170
pF1KB8 EMPAGKDQEASRGSVPSGSKMDRRAPVPRTKASGTEHNKKGTKERTNGDIVPERGDIEHK
. ... .: :. :: :. :: : :.
CCDS65 MVILFQNEGTS--SIRSG-KL-RRQPQPH-------------------------------
110 120
180 190 200 210 220 230
pF1KB8 KRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAF
:: ::
CCDS65 ----------PPREE---------------------------------------------
130
240 250 260 270 280 290
pF1KB8 GGLTRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIR
CCDS65 ------------------------------------------------------------
300 310 320 330 340 350
pF1KB8 PENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQV
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 ---------LEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQV
140 150 160 170 180
360 370 380 390 400 410
pF1KB8 KSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS65 KSGRPSLRLLSEKILGLQVQQAEHCSIQDAQAAMRLYVMVKKEWESMARDRRPLLTAPDH
190 200 210 220 230 240
420
pF1KB8 CSDDA
:::::
CCDS65 CSDDA
250
>>CCDS10344.1 AEN gene_id:64782|Hs108|chr15 (325 aa)
initn: 498 init1: 385 opt: 515 Z-score: 433.9 bits: 88.9 E(32554): 7.5e-18
Smith-Waterman score: 515; 39.1% identity (67.8% similar) in 230 aa overlap (201-422:65-292)
180 190 200 210 220 230
pF1KB8 RGDIEHKKRKAKEAAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLS
:. . :: . :::. ... : . ::. :
CCDS10 RQHQRFMARKALLQEQGLLSMPPEPGSSPLPTPFGAATATEAASSGKQCLRAGSGSAPCS
40 50 60 70 80 90
240 250 260 270 280
pF1KB8 L--VKEQAFGGL-TRALALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVT
. .: : : .. .:.::::::.::.:. : :: :::. .:. .::::..: :..
CCDS10 RRPAPGKASGPLPSKCVAIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 DYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDT
:::: ::: ...... ..:.:::. ..:::...::::::::...: ::... :::
CCDS10 DYRTRWSGITRQHMRKAVPFQVAQKEILKLLKGKVVVGHALHNDFQALKYVHPRSQTRDT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 QKYKPFKSQV---KSGRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWE
: :. .: ::. :. ..: .:: : : :..:: .::.:: .:. .::
CCDS10 TYVPNFLSEPGLHTRARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWE
220 230 240 250 260 270
410 420
pF1KB8 SMARDRRPLLTAPDHCSDDA
. .. : : : :. :.
CCDS10 Q--QEARSLWTCPEDREPDSSTDMEQYMEDQYWPDDLAHGSRGGAREAQDRRN
280 290 300 310 320
>>CCDS1153.1 ISG20L2 gene_id:81875|Hs108|chr1 (353 aa)
initn: 478 init1: 338 opt: 458 Z-score: 387.0 bits: 80.4 E(32554): 3.1e-15
Smith-Waterman score: 481; 31.8% identity (61.1% similar) in 321 aa overlap (98-407:50-349)
70 80 90 100 110 120
pF1KB8 QNWKALQEWLLKQKSQAPEKPLVISQMGSKKKPKIIQQ-NKKETSPQVKGE-EMPAGKDQ
: ::. .. .:: .: : : . :. .
CCDS11 EGNAKHRNFVKKRRLLERRGFLSKKNQPPSKAPKLHSEPSKKGETPTVDGTWKTPSFPKK
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB8 EASRGSVPSGSKMDRRAPVPR-TKASGTEHNKKGTKERTNGDIVPERGDIE-HKKRKAKE
... .: ::. .:..: : : : . . .. ..: :.. :. : :. :.
CCDS11 KTAASSNGSGQPLDKKAAVSWLTPAPSKKADSVAAKVDLLGEFQSALPKINSHPTRSQKK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB8 AAPAPPTEEDIWFDDVDPADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRA
.. .... :. . ..::.. : . : : :
CCDS11 SSQKKSSKKN---------------HPQKNAPQNSTQAHSENKCSGASQK------LPRK
140 150 160 170
250 260 270 280 290 300
pF1KB8 L-ALDCEMVGVGPKGEESMAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLK
. :.::::::.::::. : :: :::: : .::.:. : ..:::: :::: ...
CCDS11 MVAIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMV
180 190 200 210 220 230
310 320 330 340 350
pF1KB8 QGEELEVVQKEVAEMLKGRILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQV---KS
.. ..... .. ..: :.:.::::.:::.:.: :::. :::.. :.. .. ..
CCDS11 NATPFKIARGQILKILTGKIVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRKADCPEN
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB8 GRPSLRLLSEKILG--LQVQQAEHCSIQDAQAAMRLYVMVKKEWES-MARDRRPLLTAPD
. ::. :..:.:. .:: .. : :..::::.:.:: .:. ::: .::.
CCDS11 ATMSLKHLTKKLLNRDIQVGKSGHSSVEDAQATMELYKLVEVEWEEHLARNPPTD
300 310 320 330 340 350
420
pF1KB8 HCSDDA
>>CCDS10345.1 ISG20 gene_id:3669|Hs108|chr15 (181 aa)
initn: 297 init1: 240 opt: 389 Z-score: 335.1 bits: 69.8 E(32554): 2.4e-12
Smith-Waterman score: 389; 37.8% identity (67.6% similar) in 185 aa overlap (239-416:3-181)
210 220 230 240 250 260
pF1KB8 GPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRALALDCEMVGVGPKGEESMAARVSIV
: ...:.::::::.::. .:: :: :.:
CCDS10 MAGSREVVAMDCEMVGLGPH-RESGLARCSLV
10 20 30
270 280 290 300 310 320
pF1KB8 NQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENLKQGEELEVVQKEVAEMLKGRILVGHAL
: .: .:::...: .::::: :::. :... . . :.. :. ..:::...::: :
CCDS10 NVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPFAVARLEILQLLKGKLVVGHDL
40 50 60 70 80 90
330 340 350 360 370 380
pF1KB8 HNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSG---RPSLRLLSEKILGLQVQQAE--HCS
..:...: : : ::. . . ..: : :::.:::..: ..:.. : :
CCDS10 KHDFQALKEDMSGYTIYDTSTDRLLWREAKLDHCRRVSLRVLSERLLHKSIQNSLLGHSS
100 110 120 130 140 150
390 400 410 420
pF1KB8 IQDAQAAMRLYVMVKKEWESMARDRR--PLLTAPDHCSDDA
..::.:.:.:: . .. : :: : :.. :
CCDS10 VEDARATMELYQISQR-----IRARRGLPRLAVSD
160 170 180
422 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:27:35 2016 done: Mon Nov 7 03:27:35 2016
Total Scan time: 2.680 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]