Result of FASTA (omim) for
pFN21AB7962
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7962, 397 aa
1>>>pF1KB7962 397 - 397 aa - 397 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6007+/-0.000389; mu= 20.0067+/- 0.025
mean_var=237.3276+/-51.663, 0's: 0 Z-trim(120.2): 368 B-trim: 0 in 0/54
Lambda= 0.083253
statistics sampled from 34721 (35195) to 34721 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.755), E-opt: 0.2 (0.413), width: 16
Scan time: 9.710
The best scores are: opt bits E(85289)
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 2730 340.8 3.3e-93
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 2590 324.0 3.8e-88
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 2590 324.0 3.9e-88
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 2585 323.4 5.7e-88
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 2041 258.0 2.5e-68
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 1029 136.4 9.5e-32
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 1029 136.6 1.1e-31
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 514 74.6 4.2e-13
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 514 74.9 5.1e-13
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 475 69.9 1.1e-11
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 468 69.1 2e-11
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 457 67.8 5.1e-11
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 451 66.3 5.3e-11
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 451 66.3 5.3e-11
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 451 66.3 5.3e-11
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 451 66.3 5.3e-11
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 451 66.3 5.3e-11
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 451 66.3 5.3e-11
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 451 66.3 5.3e-11
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 451 66.3 5.3e-11
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 451 66.4 5.4e-11
NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 451 66.4 5.5e-11
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 454 67.5 6.5e-11
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 453 67.3 6.9e-11
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 451 67.1 8.3e-11
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 444 65.7 1.1e-10
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 440 65.1 1.4e-10
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 438 64.8 1.6e-10
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363) 436 65.2 2.8e-10
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366) 436 65.3 2.8e-10
NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 377) 436 65.3 2.9e-10
XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobo ( 378) 436 65.3 2.9e-10
NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 392) 436 65.3 2.9e-10
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 433 64.5 2.9e-10
XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobo ( 407) 436 65.3 3e-10
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 428 63.6 3.6e-10
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 428 63.6 3.6e-10
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 426 63.4 4.5e-10
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 426 63.4 4.5e-10
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 426 64.1 6.8e-10
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 422 63.7 9.5e-10
XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 348 54.0 2.9e-07
XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 348 54.0 2.9e-07
>>NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 iso (397 aa)
initn: 2730 init1: 2730 opt: 2730 Z-score: 1794.3 bits: 340.8 E(85289): 3.3e-93
Smith-Waterman score: 2730; 100.0% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT
310 320 330 340 350 360
370 380 390
pF1KB7 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
:::::::::::::::::::::::::::::::::::::
NP_064 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
370 380 390
>>NP_001014434 (OMIM: 606066) LIM/homeobox protein Lhx9 (388 aa)
initn: 2590 init1: 2590 opt: 2590 Z-score: 1703.5 bits: 324.0 E(85289): 3.8e-88
Smith-Waterman score: 2590; 100.0% identity (100.0% similar) in 379 aa overlap (19-397:10-388)
10 20 30 40 50 60
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM
::::::::::::::::::::::::::::::::::::::::::
NP_001 MLNGTTLEAAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT
300 310 320 330 340 350
370 380 390
pF1KB7 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
:::::::::::::::::::::::::::::::::::::
NP_001 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
360 370 380
>>XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobox pr (403 aa)
initn: 2590 init1: 2590 opt: 2590 Z-score: 1703.3 bits: 324.0 E(85289): 3.9e-88
Smith-Waterman score: 2590; 100.0% identity (100.0% similar) in 379 aa overlap (19-397:25-403)
10 20 30 40 50
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLN
::::::::::::::::::::::::::::::::::::
XP_011 MQTLQTPSPLRMKPASSRVSGPQEAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 GRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 DGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 GMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 KDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALT
310 320 330 340 350 360
360 370 380 390
pF1KB7 PPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
:::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
370 380 390 400
>>XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobox pr (378 aa)
initn: 2585 init1: 2585 opt: 2585 Z-score: 1700.3 bits: 323.4 E(85289): 5.7e-88
Smith-Waterman score: 2585; 100.0% identity (100.0% similar) in 378 aa overlap (20-397:1-378)
10 20 30 40 50 60
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM
:::::::::::::::::::::::::::::::::::::::::
XP_016 MLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGM
10 20 30 40
70 80 90 100 110 120
pF1KB7 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYC
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTAT
290 300 310 320 330 340
370 380 390
pF1KB7 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
:::::::::::::::::::::::::::::::::::::
XP_016 TLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
350 360 370
>>XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobox pr (336 aa)
initn: 2041 init1: 2041 opt: 2041 Z-score: 1347.6 bits: 258.0 E(85289): 2.5e-68
Smith-Waterman score: 2041; 100.0% identity (100.0% similar) in 294 aa overlap (19-312:25-318)
10 20 30 40 50
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLN
::::::::::::::::::::::::::::::::::::
XP_005 MQTLQTPSPLRMKPASSRVSGPQEAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 GRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRDAGMPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 DGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 GMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMKDSLVYCRAHFETLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 KDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALT
::::::::::::::::::
XP_005 KDLKQLAQKTGLTKRVLQGEQILGHYSQTSRRLKIP
310 320 330
>>XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobox pr (314 aa)
initn: 1422 init1: 924 opt: 1029 Z-score: 691.0 bits: 136.4 E(85289): 9.5e-32
Smith-Waterman score: 1565; 73.7% identity (87.2% similar) in 312 aa overlap (20-312:1-311)
10 20 30 40 50
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNG-RDAG
::::..:: ...:...::.::.:.:: ..: : ..
XP_006 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETT
10 20 30 40
60 70 80 90 100 110
pF1KB7 MPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIY
:: .: .. ::::::::::::::::::::::::.:::::::::: ::::::::.::::::
XP_006 MPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIY
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 CKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDS
:::::::::::::::::::::::::::::::: ::::.::::.:::: ::::::::::::
XP_006 CKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDS
110 120 130 140 150 160
180 190 200 210 220
pF1KB7 LVYCRAHFETLLQGEYPPQLSYTELAA--------KSGGLA--------LPYFNGTGTVQ
::::: :::.::::::: .......:: ::.::. :::.::.::::
XP_006 LVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB7 KGRPRKRKSPALGVDIVNYNSG--CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRT
::::::::::. :.:.. ::.. ::::.:.:::::: ::: ::::::::::::::::::
XP_006 KGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFKHHQLRT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTS
:::::::::::::::::::::::::::::::
XP_006 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQASL
290 300 310
350 360 370 380 390
pF1KB7 LPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHESGSPSQTTLTNLF
>>NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 [Ho (406 aa)
initn: 1824 init1: 930 opt: 1029 Z-score: 690.0 bits: 136.6 E(85289): 1.1e-31
Smith-Waterman score: 1891; 70.3% identity (85.5% similar) in 407 aa overlap (20-397:1-406)
10 20 30 40 50
pF1KB7 MEIVGCRAEDNSCPFRPPAMLFHGISGGHIQGIMEEMERRSKTEARLAKGAQLNG-RDAG
::::..:: ...:...::.::.:.:: ..: : ..
NP_004 MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETT
10 20 30 40
60 70 80 90 100 110
pF1KB7 MPPLSPEKPALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIY
:: .: .. ::::::::::::::::::::::::.:::::::::: ::::::::.::::::
NP_004 MPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIY
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 CKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDS
:::::::::::::::::::::::::::::::: ::::.::::.:::: ::::::::::::
NP_004 CKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDS
110 120 130 140 150 160
180 190 200 210 220
pF1KB7 LVYCRAHFETLLQGEYPPQLSYTELAA--------KSGGLA--------LPYFNGTGTVQ
::::: :::.::::::: .......:: ::.::. :::.::.::::
NP_004 LVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB7 KGRPRKRKSPALGVDIVNYNSG--CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRT
::::::::::. :.:.. ::.. ::::.:.:::::: ::: ::::::::::::::::::
NP_004 KGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQ-PYPSSQKTKRMRTSFKHHQLRT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB7 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENGGVDKADGTS
:::::::::::::::::::::::::::::::::::::::::::::::::: ::::. ..
NP_004 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAA
290 300 310 320 330 340
350 360 370 380 390
pF1KB7 L----PAPPSAD--SGALTPPGTATTLTDLTNPTI----TVVTSVTSNMDSHESGSPSQT
: :. :... ...:.: .: :::::::.::. .:.::: .:...:: :::::
NP_004 LQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQT
350 360 370 380 390 400
pF1KB7 TLTNLF
::::::
NP_004 TLTNLF
>>NP_665804 (OMIM: 609481) insulin gene enhancer protein (359 aa)
initn: 412 init1: 250 opt: 514 Z-score: 356.2 bits: 74.6 E(85289): 4.2e-13
Smith-Waterman score: 621; 37.3% identity (62.4% similar) in 287 aa overlap (60-342:14-267)
30 40 50 60 70 80
pF1KB7 IQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKP--ALCAGCGGKISDRYYL-LA
: : .:: :.:.:::..: :.. : ..
NP_665 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVS
10 20 30 40
90 100 110 120 130 140
pF1KB7 VDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMV
: .:: :::: ::. :. :::..::. :::.:: : :.. .::.:..:.:.:..:
NP_665 PDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGI-KCAKCQVGFSSSDLV
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB7 MRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAA
:::::::::. :: ::.:.. : ::.:.... . ::: ::. . .
NP_665 MRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLE-------RAAAGSP
110 120 130 140 150
210 220 230 240 250 260
pF1KB7 KSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQK
.: : :: : . : :. ::: :. .. ..:
NP_665 RSPG-PLPGARGLHLPDAGSGRQ---PAL---------------RPHVHKQ------TEK
160 170 180 190
270 280 290 300 310 320
pF1KB7 TKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK-FRRN
: :.:: ....::.:... .: : ::: .::.. :::. ::..::::: : : ...
NP_665 TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKS
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB7 LLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHES
.: .. ...: :::
NP_665 ILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQ
260 270 280 290 300 310
>>XP_016877994 (OMIM: 609481) PREDICTED: insulin gene en (534 aa)
initn: 412 init1: 250 opt: 514 Z-score: 354.7 bits: 74.9 E(85289): 5.1e-13
Smith-Waterman score: 621; 37.3% identity (62.4% similar) in 287 aa overlap (60-342:14-267)
30 40 50 60 70 80
pF1KB7 IQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKP--ALCAGCGGKISDRYYL-LA
: : .:: :.:.:::..: :.. : ..
XP_016 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVS
10 20 30 40
90 100 110 120 130 140
pF1KB7 VDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMV
: .:: :::: ::. :. :::..::. :::.:: : :.. .::.:..:.:.:..:
XP_016 PDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGI-KCAKCQVGFSSSDLV
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB7 MRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELAA
:::::::::. :: ::.:.. : ::.:.... . ::: ::. . .
XP_016 MRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLE-------RAAAGSP
110 120 130 140 150
210 220 230 240 250 260
pF1KB7 KSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQK
.: : :: : . : :. ::: :. .. ..:
XP_016 RSPG-PLPGARGLHLPDAGSGRQ---PAL---------------RPHVHKQ------TEK
160 170 180 190
270 280 290 300 310 320
pF1KB7 TKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK-FRRN
: :.:: ....::.:... .: : ::: .::.. :::. ::..::::: : : ...
XP_016 TTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKS
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB7 LLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNPTITVVTSVTSNMDSHES
.: .. ...: :::
XP_016 ILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEFALQ
260 270 280 290 300 310
>>NP_002193 (OMIM: 600366) insulin gene enhancer protein (349 aa)
initn: 421 init1: 259 opt: 475 Z-score: 331.0 bits: 69.9 E(85289): 1.1e-11
Smith-Waterman score: 604; 34.5% identity (61.7% similar) in 313 aa overlap (57-356:3-281)
30 40 50 60 70 80
pF1KB7 GGHIQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPEKPALCAGCGGKISDRYYL-L
: : :: . . .::.:::..: :.: : .
NP_002 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRV
10 20 30
90 100 110 120 130 140
pF1KB7 AVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEM
. : .:: :::: ::. :. :::..::. :::.:: : ... .::.: .:.: ...
NP_002 SPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGI-KCAKCSIGFSKNDF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB7 VMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQLSYTELA
:::::..:::. :: : .:.. : ::.:..... ..::: ... : :
NP_002 VMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVV------------ERA
100 110 120 130
210 220 230 240 250 260
pF1KB7 AKSGGLALPYFNGTGTVQ-KGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPS
. ..: : .. . .: ..: . ..::: :. . ::
NP_002 SLGAGDPLSPLHPARPLQMAAEPISARQPAL---------------RPHVHK--QP----
140 150 160 170
270 280 290 300 310 320
pF1KB7 QKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAK-FR
.:: :.:: ....::.:... .: : ::: .::.. :::. ::..::::: : : .
NP_002 EKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK
180 190 200 210 220 230
330 340 350 360 370
pF1KB7 RNLLR---QENGGVDKAD-----GTSLPA--PPSADSGALTPPGTATTLTDLTNPTITVV
:... :.. ::.. :: . : : :.: . :
NP_002 RSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFA
240 250 260 270 280 290
380 390
pF1KB7 TSVTSNMDSHESGSPSQTTLTNLF
NP_002 LQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
300 310 320 330 340
397 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:31:09 2016 done: Sun Nov 6 05:31:11 2016
Total Scan time: 9.710 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]