Result of FASTA (omim) for
pFN21AB7872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7872, 636 aa
1>>>pF1KB7872 636 - 636 aa - 636 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4501+/-0.000346; mu= 5.2758+/- 0.022
mean_var=163.5820+/-33.818, 0's: 0 Z-trim(120.5): 44 B-trim: 1501 in 2/56
Lambda= 0.100278
statistics sampled from 35792 (35836) to 35792 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.42), width: 16
Scan time: 11.360
The best scores are: opt bits E(85289)
NP_005418 (OMIM: 601990) tumor protein p73 isoform ( 636) 4352 641.7 2.4e-183
NP_001119712 (OMIM: 601990) tumor protein p73 isof ( 587) 3940 582.0 2e-165
NP_001191121 (OMIM: 601990) tumor protein p73 isof ( 565) 3888 574.5 3.5e-163
NP_001191113 (OMIM: 601990) tumor protein p73 isof ( 499) 3375 500.3 6.9e-141
NP_001119713 (OMIM: 601990) tumor protein p73 isof ( 450) 2963 440.6 5.5e-123
NP_001191114 (OMIM: 601990) tumor protein p73 isof ( 475) 2710 404.0 6e-112
NP_001191116 (OMIM: 601990) tumor protein p73 isof ( 555) 2710 404.1 6.9e-112
NP_001191115 (OMIM: 601990) tumor protein p73 isof ( 403) 2695 401.8 2.4e-111
NP_001191117 (OMIM: 601990) tumor protein p73 isof ( 540) 2693 401.6 3.7e-111
NP_001119714 (OMIM: 601990) tumor protein p73 isof ( 426) 2298 344.4 4.8e-94
NP_001191119 (OMIM: 601990) tumor protein p73 isof ( 506) 2298 344.5 5.6e-94
XP_005247901 (OMIM: 103285,106260,129400,603273,60 ( 663) 2297 344.4 7.7e-94
NP_001316893 (OMIM: 103285,106260,129400,603273,60 ( 678) 2297 344.4 7.9e-94
XP_011511553 (OMIM: 103285,106260,129400,603273,60 ( 679) 2297 344.4 7.9e-94
NP_003713 (OMIM: 103285,106260,129400,603273,60354 ( 680) 2297 344.4 7.9e-94
NP_001191118 (OMIM: 601990) tumor protein p73 isof ( 354) 2283 342.2 1.9e-93
NP_001191120 (OMIM: 601990) tumor protein p73 isof ( 491) 2281 342.0 3e-93
NP_001108452 (OMIM: 103285,106260,129400,603273,60 ( 586) 2273 340.9 7.7e-93
NP_001316077 (OMIM: 103285,106260,129400,603273,60 ( 676) 2270 340.5 1.2e-92
XP_016862876 (OMIM: 103285,106260,129400,603273,60 ( 582) 2246 337.0 1.2e-91
NP_001316075 (OMIM: 103285,106260,129400,603273,60 ( 501) 1926 290.6 8.8e-78
NP_001108450 (OMIM: 103285,106260,129400,603273,60 ( 555) 1865 281.8 4.3e-75
NP_001108453 (OMIM: 103285,106260,129400,603273,60 ( 461) 1841 278.3 4.1e-74
NP_001316073 (OMIM: 103285,106260,129400,603273,60 ( 510) 1764 267.2 1e-70
NP_001316074 (OMIM: 103285,106260,129400,603273,60 ( 416) 1740 263.7 9.4e-70
NP_001316078 (OMIM: 103285,106260,129400,603273,60 ( 412) 1713 259.8 1.4e-68
NP_001108451 (OMIM: 103285,106260,129400,603273,60 ( 487) 1645 250.0 1.5e-65
NP_001108454 (OMIM: 103285,106260,129400,603273,60 ( 393) 1621 246.5 1.4e-64
NP_001316079 (OMIM: 103285,106260,129400,603273,60 ( 327) 1366 209.5 1.5e-53
NP_001263689 (OMIM: 114480,114500,114550,137800,15 ( 354) 935 147.2 9.4e-35
NP_001119590 (OMIM: 114480,114500,114550,137800,15 ( 354) 935 147.2 9.4e-35
NP_001263690 (OMIM: 114480,114500,114550,137800,15 ( 354) 935 147.2 9.4e-35
NP_001119584 (OMIM: 114480,114500,114550,137800,15 ( 393) 935 147.2 1e-34
NP_000537 (OMIM: 114480,114500,114550,137800,15162 ( 393) 935 147.2 1e-34
NP_001263624 (OMIM: 114480,114500,114550,137800,15 ( 307) 861 136.5 1.4e-31
NP_001263625 (OMIM: 114480,114500,114550,137800,15 ( 302) 860 136.3 1.5e-31
NP_001119585 (OMIM: 114480,114500,114550,137800,15 ( 346) 861 136.5 1.5e-31
NP_001119586 (OMIM: 114480,114500,114550,137800,15 ( 341) 860 136.3 1.7e-31
NP_001119587 (OMIM: 114480,114500,114550,137800,15 ( 261) 798 127.3 6.7e-29
NP_001119589 (OMIM: 114480,114500,114550,137800,15 ( 214) 724 116.6 9.5e-26
NP_001119588 (OMIM: 114480,114500,114550,137800,15 ( 209) 723 116.4 1e-25
NP_001263626 (OMIM: 114480,114500,114550,137800,15 ( 234) 657 106.9 8.5e-23
NP_001263628 (OMIM: 114480,114500,114550,137800,15 ( 187) 583 96.1 1.2e-19
NP_001263627 (OMIM: 114480,114500,114550,137800,15 ( 182) 582 96.0 1.3e-19
>>NP_005418 (OMIM: 601990) tumor protein p73 isoform a [ (636 aa)
initn: 4352 init1: 4352 opt: 4352 Z-score: 3412.7 bits: 641.7 E(85289): 2.4e-183
Smith-Waterman score: 4352; 100.0% identity (100.0% similar) in 636 aa overlap (1-636:1-636)
10 20 30 40 50 60
pF1KB7 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 CTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 IWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRG
550 560 570 580 590 600
610 620 630
pF1KB7 GPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
::::::::::::::::::::::::::::::::::::
NP_005 GPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
610 620 630
>>NP_001119712 (OMIM: 601990) tumor protein p73 isoform (587 aa)
initn: 3940 init1: 3940 opt: 3940 Z-score: 3091.1 bits: 582.0 E(85289): 2e-165
Smith-Waterman score: 3940; 100.0% identity (100.0% similar) in 574 aa overlap (63-636:14-587)
40 50 60 70 80 90
pF1KB7 QSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAAS
::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAAS
10 20 30 40
100 110 120 130 140 150
pF1KB7 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB7 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
350 360 370 380 390 400
460 470 480 490 500 510
pF1KB7 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQ
410 420 430 440 450 460
520 530 540 550 560 570
pF1KB7 GLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIG
470 480 490 500 510 520
580 590 600 610 620 630
pF1KB7 GSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTE
530 540 550 560 570 580
pF1KB7 AEIH
::::
NP_001 AEIH
>>NP_001191121 (OMIM: 601990) tumor protein p73 isoform (565 aa)
initn: 3888 init1: 3888 opt: 3888 Z-score: 3050.7 bits: 574.5 E(85289): 3.5e-163
Smith-Waterman score: 3888; 100.0% identity (100.0% similar) in 565 aa overlap (72-636:1-565)
50 60 70 80 90 100
pF1KB7 VGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQ
::::::::::::::::::::::::::::::
NP_001 MDQMSSRAASASPYTPEHAASVPTHSPYAQ
10 20 30
110 120 130 140 150 160
pF1KB7 PSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPI
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB7 QIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNN
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB7 LSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRD
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB7 GQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALG
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB7 AGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSH
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB7 LQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB7 ANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQ
400 410 420 430 440 450
530 540 550 560 570 580
pF1KB7 NLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQR
460 470 480 490 500 510
590 600 610 620 630
pF1KB7 VMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
520 530 540 550 560
>>NP_001191113 (OMIM: 601990) tumor protein p73 isoform (499 aa)
initn: 3375 init1: 3375 opt: 3375 Z-score: 2650.4 bits: 500.3 E(85289): 6.9e-141
Smith-Waterman score: 3375; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KB7 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 CTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMT
::::::::::::::
NP_001 CTPPPPYHADPSLVRTWGP
490
>>NP_001119713 (OMIM: 601990) tumor protein p73 isoform (450 aa)
initn: 2963 init1: 2963 opt: 2963 Z-score: 2328.9 bits: 440.6 E(85289): 5.5e-123
Smith-Waterman score: 2963; 100.0% identity (100.0% similar) in 432 aa overlap (63-494:14-445)
40 50 60 70 80 90
pF1KB7 QSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAAS
::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAAS
10 20 30 40
100 110 120 130 140 150
pF1KB7 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB7 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
350 360 370 380 390 400
460 470 480 490 500 510
pF1KB7 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQ
::::::::::::::::::::::::::::::::::::::::::
NP_001 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
410 420 430 440 450
520 530 540 550 560 570
pF1KB7 GLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIG
>>NP_001191114 (OMIM: 601990) tumor protein p73 isoform (475 aa)
initn: 2693 init1: 2693 opt: 2710 Z-score: 2130.8 bits: 404.0 E(85289): 6e-112
Smith-Waterman score: 2710; 92.8% identity (94.4% similar) in 443 aa overlap (1-436:1-443)
10 20 30 40 50 60
pF1KB7 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSH--LQP-PSYGPV----LSP
::::::::::::::::::::::::::::::::::::::: . :: : . .:
NP_001 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPPRDAQQPWPRSASQRRDEQQP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 MNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQ
. ::: : :.. : .: :
NP_001 QRPVHGLGVPLHSATPLPRRPQPRQFFNRIGVSKLHRVFHLPRVTEHLPPAEPDH
430 440 450 460 470
>>NP_001191116 (OMIM: 601990) tumor protein p73 isoform (555 aa)
initn: 3439 init1: 2693 opt: 2710 Z-score: 2129.7 bits: 404.1 E(85289): 6.9e-112
Smith-Waterman score: 3333; 82.9% identity (83.8% similar) in 637 aa overlap (1-636:1-555)
10 20 30 40 50 60
pF1KB7 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
:::::::::::::::::::::::::::::::::::::::
NP_001 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRP---------------------
370 380 390
430 440 450 460 470
pF1KB7 MNKLPSVNQLVGQPPPHS-SAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGS
: : :: :.: : . : : :: .:: :::
NP_001 ----PRDAQ---QPWPRSASQRRDEQQPQRP----VHGLGVPL-------HSAT------
400 410 420 430
480 490 500 510 520 530
pF1KB7 HCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRM
: : . .: .:::::::::::::
NP_001 ----PLPRRPQPR---------------------------------QDLGALKIPEQYRM
440 450
540 550 560 570 580 590
pF1KB7 TIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNR
460 470 480 490 500 510
600 610 620 630
pF1KB7 GGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
:::::::::::::::::::::::::::::::::::::
NP_001 GGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
520 530 540 550
>>NP_001191115 (OMIM: 601990) tumor protein p73 isoform (403 aa)
initn: 2695 init1: 2695 opt: 2695 Z-score: 2120.1 bits: 401.8 E(85289): 2.4e-111
Smith-Waterman score: 2695; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB7 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
:::::::::::::::::::::::::::::::::::::::.
NP_001 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPTWGP
370 380 390 400
430 440 450 460 470 480
pF1KB7 MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSH
>>NP_001191117 (OMIM: 601990) tumor protein p73 isoform (540 aa)
initn: 3651 init1: 2693 opt: 2693 Z-score: 2116.6 bits: 401.6 E(85289): 3.7e-111
Smith-Waterman score: 3463; 84.9% identity (84.9% similar) in 636 aa overlap (1-636:1-540)
10 20 30 40 50 60
pF1KB7 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGG
:::::::::::::::::::::::::::::::::::::::
NP_001 GRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRP---------------------
370 380 390
430 440 450 460 470 480
pF1KB7 MNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSH
NP_001 ------------------------------------------------------------
490 500 510 520 530 540
pF1KB7 CTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMT
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------------FLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMT
400 410 420 430 440
550 560 570 580 590 600
pF1KB7 IWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRG
450 460 470 480 490 500
610 620 630
pF1KB7 GPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
::::::::::::::::::::::::::::::::::::
NP_001 GPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH
510 520 530 540
>>NP_001119714 (OMIM: 601990) tumor protein p73 isoform (426 aa)
initn: 2281 init1: 2281 opt: 2298 Z-score: 1809.4 bits: 344.4 E(85289): 4.8e-94
Smith-Waterman score: 2298; 91.6% identity (93.4% similar) in 381 aa overlap (63-436:14-394)
40 50 60 70 80 90
pF1KB7 QSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAAS
::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAAS
10 20 30 40
100 110 120 130 140 150
pF1KB7 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB7 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB7 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB7 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
230 240 250 260 270 280
340 350 360 370 380 390
pF1KB7 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
290 300 310 320 330 340
400 410 420 430 440
pF1KB7 QQLLQRPSH--LQP-PSYGPV----LSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNL
::::::: . :: : . .:. ::: : :.. : .: :
NP_001 QQLLQRPPRDAQQPWPRSASQRRDEQQPQRPVHGLGVPLHSATPLPRRPQPRQFFNRIGV
350 360 370 380 390 400
450 460 470 480 490 500
pF1KB7 GPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNC
NP_001 SKLHRVFHLPRVTEHLPPAEPDH
410 420
636 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:34:14 2016 done: Sun Nov 6 19:34:16 2016
Total Scan time: 11.360 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]