Result of FASTA (omim) for
pFN21AB7735
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7735, 436 aa
1>>>pF1KB7735 436 - 436 aa - 436 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5210+/-0.000354; mu= 5.0499+/- 0.023
mean_var=237.8184+/-46.998, 0's: 0 Z-trim(122.4): 72 B-trim: 34 in 1/58
Lambda= 0.083167
statistics sampled from 40513 (40600) to 40513 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.476), width: 16
Scan time: 10.830
The best scores are: opt bits E(85289)
NP_055167 (OMIM: 607394) POU domain, class 2, tran ( 436) 2932 364.4 3.2e-100
XP_011541042 (OMIM: 607394) PREDICTED: POU domain, ( 432) 2875 357.6 3.7e-98
XP_011541041 (OMIM: 607394) PREDICTED: POU domain, ( 432) 2875 357.6 3.7e-98
NP_001231611 (OMIM: 607394) POU domain, class 2, t ( 438) 2875 357.6 3.7e-98
XP_011541044 (OMIM: 607394) PREDICTED: POU domain, ( 403) 2652 330.8 4e-90
XP_011541043 (OMIM: 607394) PREDICTED: POU domain, ( 403) 2652 330.8 4e-90
XP_011541045 (OMIM: 607394) PREDICTED: POU domain, ( 403) 2652 330.8 4e-90
XP_016872976 (OMIM: 607394) PREDICTED: POU domain, ( 356) 2386 298.8 1.5e-80
XP_016882385 (OMIM: 164176) PREDICTED: POU domain, ( 600) 1083 142.7 2.5e-33
XP_016882381 (OMIM: 164176) PREDICTED: POU domain, ( 701) 1083 142.8 2.8e-33
XP_016882379 (OMIM: 164176) PREDICTED: POU domain, ( 711) 1083 142.8 2.8e-33
XP_016882378 (OMIM: 164176) PREDICTED: POU domain, ( 711) 1083 142.8 2.8e-33
XP_016882377 (OMIM: 164176) PREDICTED: POU domain, ( 711) 1083 142.8 2.8e-33
XP_016882375 (OMIM: 164176) PREDICTED: POU domain, ( 711) 1083 142.8 2.8e-33
XP_016882376 (OMIM: 164176) PREDICTED: POU domain, ( 711) 1083 142.8 2.8e-33
XP_016882374 (OMIM: 164176) PREDICTED: POU domain, ( 723) 1083 142.8 2.8e-33
XP_016882373 (OMIM: 164176) PREDICTED: POU domain, ( 723) 1083 142.8 2.8e-33
XP_011525343 (OMIM: 164176) PREDICTED: POU domain, ( 501) 1076 141.8 3.9e-33
XP_011525342 (OMIM: 164176) PREDICTED: POU domain, ( 624) 1076 141.9 4.5e-33
XP_011525345 (OMIM: 164176) PREDICTED: POU domain, ( 537) 1073 141.5 5.2e-33
NP_001193955 (OMIM: 164176) POU domain, class 2, t ( 467) 1071 141.2 5.6e-33
NP_001193954 (OMIM: 164176) POU domain, class 2, t ( 479) 1071 141.2 5.7e-33
XP_016882384 (OMIM: 164176) PREDICTED: POU domain, ( 602) 1071 141.3 6.7e-33
XP_016882383 (OMIM: 164176) PREDICTED: POU domain, ( 602) 1071 141.3 6.7e-33
NP_001185715 (OMIM: 164175) POU domain, class 2, t ( 703) 1033 136.8 1.8e-31
XP_011507957 (OMIM: 164175) PREDICTED: POU domain, ( 671) 1000 132.8 2.7e-30
XP_011507956 (OMIM: 164175) PREDICTED: POU domain, ( 743) 1000 132.8 2.9e-30
NP_001185712 (OMIM: 164175) POU domain, class 2, t ( 755) 1000 132.8 2.9e-30
NP_002688 (OMIM: 164175) POU domain, class 2, tran ( 766) 1000 132.8 2.9e-30
XP_011507955 (OMIM: 164175) PREDICTED: POU domain, ( 769) 1000 132.8 2.9e-30
NP_002689 (OMIM: 164176) POU domain, class 2, tran ( 463) 934 124.7 4.9e-28
XP_005259067 (OMIM: 164176) PREDICTED: POU domain, ( 586) 934 124.8 5.8e-28
XP_011525344 (OMIM: 164176) PREDICTED: POU domain, ( 485) 931 124.4 6.6e-28
XP_016882382 (OMIM: 164176) PREDICTED: POU domain, ( 608) 931 124.5 7.7e-28
NP_001234923 (OMIM: 164176) POU domain, class 2, t ( 400) 924 123.5 1e-27
XP_016882380 (OMIM: 164176) PREDICTED: POU domain, ( 707) 920 123.2 2.1e-27
NP_002690 (OMIM: 602479) POU domain, class 3, tran ( 451) 701 96.7 1.3e-19
NP_005595 (OMIM: 600494) POU domain, class 3, tran ( 443) 690 95.4 3.1e-19
NP_006227 (OMIM: 602480) POU domain, class 3, tran ( 500) 670 93.1 1.8e-18
NP_000298 (OMIM: 300039,304400) POU domain, class ( 361) 666 92.5 2e-18
XP_016856997 (OMIM: 164175) PREDICTED: POU domain, ( 381) 602 84.8 4.2e-16
NP_001272916 (OMIM: 164177) POU domain, class 5, t ( 265) 552 78.6 2.1e-14
NP_002692 (OMIM: 164177) POU domain, class 5, tran ( 360) 554 79.0 2.2e-14
NP_004566 (OMIM: 113725) POU domain, class 4, tran ( 409) 542 77.6 6.5e-14
NP_001153014 (OMIM: 615739) putative POU domain, c ( 359) 521 75.1 3.4e-13
NP_000297 (OMIM: 173110,613038) pituitary-specific ( 291) 515 74.2 4.8e-13
NP_001116229 (OMIM: 173110,613038) pituitary-speci ( 317) 515 74.3 5.1e-13
NP_002691 (OMIM: 602459,602460) POU domain, class ( 338) 492 71.5 3.6e-12
NP_006228 (OMIM: 601632) POU domain, class 4, tran ( 419) 481 70.3 1.1e-11
NP_001159490 (OMIM: 601583,609062) POU domain, cla ( 655) 471 69.3 3.3e-11
>>NP_055167 (OMIM: 607394) POU domain, class 2, transcri (436 aa)
initn: 2932 init1: 2932 opt: 2932 Z-score: 1920.2 bits: 364.4 E(85289): 3.2e-100
Smith-Waterman score: 2932; 100.0% identity (100.0% similar) in 436 aa overlap (1-436:1-436)
10 20 30 40 50 60
pF1KB7 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
370 380 390 400 410 420
430
pF1KB7 NSSGSWYRWNHSTYLH
::::::::::::::::
NP_055 NSSGSWYRWNHSTYLH
430
>>XP_011541042 (OMIM: 607394) PREDICTED: POU domain, cla (432 aa)
initn: 2875 init1: 2875 opt: 2875 Z-score: 1883.3 bits: 357.6 E(85289): 3.7e-98
Smith-Waterman score: 2875; 100.0% identity (100.0% similar) in 427 aa overlap (10-436:6-432)
10 20 30 40 50 60
pF1KB7 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNDAKDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
360 370 380 390 400 410
430
pF1KB7 NSSGSWYRWNHSTYLH
::::::::::::::::
XP_011 NSSGSWYRWNHSTYLH
420 430
>>XP_011541041 (OMIM: 607394) PREDICTED: POU domain, cla (432 aa)
initn: 2875 init1: 2875 opt: 2875 Z-score: 1883.3 bits: 357.6 E(85289): 3.7e-98
Smith-Waterman score: 2875; 100.0% identity (100.0% similar) in 427 aa overlap (10-436:6-432)
10 20 30 40 50 60
pF1KB7 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNDAKDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
360 370 380 390 400 410
430
pF1KB7 NSSGSWYRWNHSTYLH
::::::::::::::::
XP_011 NSSGSWYRWNHSTYLH
420 430
>>NP_001231611 (OMIM: 607394) POU domain, class 2, trans (438 aa)
initn: 2875 init1: 2875 opt: 2875 Z-score: 1883.2 bits: 357.6 E(85289): 3.7e-98
Smith-Waterman score: 2875; 100.0% identity (100.0% similar) in 427 aa overlap (10-436:12-438)
10 20 30 40 50
pF1KB7 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MESPRTAKGGRDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 SHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHRPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 QQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQGLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 SGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGGADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 FKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 RFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 PSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSGSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSAS
370 380 390 400 410 420
420 430
pF1KB7 SFNSSGSWYRWNHSTYLH
::::::::::::::::::
NP_001 SFNSSGSWYRWNHSTYLH
430
>>XP_011541044 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 2652 init1: 2652 opt: 2652 Z-score: 1739.1 bits: 330.8 E(85289): 4e-90
Smith-Waterman score: 2652; 100.0% identity (100.0% similar) in 393 aa overlap (44-436:11-403)
20 30 40 50 60 70
pF1KB7 SGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMS
::::::::::::::::::::::::::::::
XP_011 MLAALSARWSQIKTEDLSDSLQQTLSHRPCHLSQGPAMMS
10 20 30 40
80 90 100 110 120 130
pF1KB7 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 SGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB7 FAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB7 NDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISM
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB7 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB7 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHST
350 360 370 380 390 400
pF1KB7 YLH
:::
XP_011 YLH
>>XP_011541043 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 2652 init1: 2652 opt: 2652 Z-score: 1739.1 bits: 330.8 E(85289): 4e-90
Smith-Waterman score: 2652; 100.0% identity (100.0% similar) in 393 aa overlap (44-436:11-403)
20 30 40 50 60 70
pF1KB7 SGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMS
::::::::::::::::::::::::::::::
XP_011 MLAALSARWSQIKTEDLSDSLQQTLSHRPCHLSQGPAMMS
10 20 30 40
80 90 100 110 120 130
pF1KB7 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 SGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB7 FAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB7 NDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISM
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB7 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB7 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHST
350 360 370 380 390 400
pF1KB7 YLH
:::
XP_011 YLH
>>XP_011541045 (OMIM: 607394) PREDICTED: POU domain, cla (403 aa)
initn: 2652 init1: 2652 opt: 2652 Z-score: 1739.1 bits: 330.8 E(85289): 4e-90
Smith-Waterman score: 2652; 100.0% identity (100.0% similar) in 393 aa overlap (44-436:11-403)
20 30 40 50 60 70
pF1KB7 SGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMS
::::::::::::::::::::::::::::::
XP_011 MLAALSARWSQIKTEDLSDSLQQTLSHRPCHLSQGPAMMS
10 20 30 40
80 90 100 110 120 130
pF1KB7 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQGLQPNLLPFPQQQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 SGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB7 FAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB7 NDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISM
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB7 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPPVHS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB7 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSFNSSGSWYRWNHST
350 360 370 380 390 400
pF1KB7 YLH
:::
XP_011 YLH
>>XP_016872976 (OMIM: 607394) PREDICTED: POU domain, cla (356 aa)
initn: 2386 init1: 2386 opt: 2386 Z-score: 1567.3 bits: 298.8 E(85289): 1.5e-80
Smith-Waterman score: 2386; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356)
10 20 30 40 50 60
pF1KB7 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVNLESMHTDIKMSGDVADSTDARSTLSQVEPGNDRNGLDFNRQIKTEDLSDSLQQTLSH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPCHLSQGPAMMSGNQMSGLNASPCQDMASLHPLQQLVLVPGHLQSVSQFLLSQTQPGQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQPNLLPFPQQQSGLLLPQTGPGLASQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GADEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRL
310 320 330 340 350
370 380 390 400 410 420
pF1KB7 GSLGPLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSASSF
>>XP_016882385 (OMIM: 164176) PREDICTED: POU domain, cla (600 aa)
initn: 644 init1: 530 opt: 1083 Z-score: 719.4 bits: 142.7 E(85289): 2.5e-33
Smith-Waterman score: 1154; 54.0% identity (70.5% similar) in 387 aa overlap (61-432:200-576)
40 50 60 70 80 90
pF1KB7 EPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMAS
.: : ... .: :.: ::. .
XP_016 SSTSSSSSSSASSSTSQPPASSGGGDLPPPQPASQPPGTPQLTLSQPIQLTA---QDIQQ
170 180 190 200 210 220
100 110 120 130 140
pF1KB7 LHPLQQLVLVPGH-LQSVSQFLLSQTQPGQQGL--QPNLLPFPQQQSG-LLLPQTGPGLA
: :::::::::: :: .:::: :.: .: :: :::. .::: .: :: : ::
XP_016 LLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLP
230 240 250 260 270 280
150 160 170 180 190 200
pF1KB7 SQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLG
.:: .: :: .::: : : :: : . .:::::::::.::.::::::::::
XP_016 TQAVTRPTLP----DPHLSHPQ--P-PKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLG
290 300 310 320 330
210 220 230 240 250 260
pF1KB7 FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVS
:::::::::::::::::::::::::::::::::::::::::::::::::::. : :.
XP_016 FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLP
340 350 360 370 380 390
270 280 290 300 310 320
pF1KB7 TPS--SYPSLSE--VFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEK
.:. : :::. . ::.::::::::::.:..::: : : ::.:::: .::::: :::
XP_016 SPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEK
400 410 420 430 440 450
330 340 350 360 370
pF1KB7 EVVRVWFCNRRQKEKRIN-CPVA----TPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPG
::.::::::::::::::: : .: .: :: :. ..:.:.:. : : . . :..
XP_016 EVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLST
460 470 480 490 500 510
380 390 400 410 420 430
pF1KB7 TVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSA--SSFNSSGSWYRWNHSTYL
:::. : .. .:: ..: ... .: :: .:. .. ::.. . .::
XP_016 TVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIG
520 530 540 550 560 570
pF1KB7 H
XP_016 LSGLNPSTGPGLWWNPAPYQP
580 590 600
>>XP_016882381 (OMIM: 164176) PREDICTED: POU domain, cla (701 aa)
initn: 664 init1: 530 opt: 1083 Z-score: 718.6 bits: 142.8 E(85289): 2.8e-33
Smith-Waterman score: 1154; 54.0% identity (70.5% similar) in 387 aa overlap (61-432:178-554)
40 50 60 70 80 90
pF1KB7 EPGNDRNGLDFNRQIKTEDLSDSLQQTLSHRPCHLSQGPAMMSGNQMSGLNASPCQDMAS
.: : ... .: :.: ::. .
XP_016 SSTSSSSSSSASSSTSQPPASSGGGDLPPPQPASQPPGTPQLTLSQPIQLTA---QDIQQ
150 160 170 180 190 200
100 110 120 130 140
pF1KB7 LHPLQQLVLVPGH-LQSVSQFLLSQTQPGQQGL--QPNLLPFPQQQSG-LLLPQTGPGLA
: :::::::::: :: .:::: :.: .: :: :::. .::: .: :: : ::
XP_016 LLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLP
210 220 230 240 250 260
150 160 170 180 190 200
pF1KB7 SQAFGHPGLPGSSLEPHLEASQHLPVPKHLPSSGGADEPSDLEELEKFAKTFKQRRIKLG
.:: .: :: .::: : : :: : . .:::::::::.::.::::::::::
XP_016 TQAVTRPTLP----DPHLSHPQ--P-PKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLG
270 280 290 300 310
210 220 230 240 250 260
pF1KB7 FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVS
:::::::::::::::::::::::::::::::::::::::::::::::::::. : :.
XP_016 FTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLP
320 330 340 350 360 370
270 280 290 300 310 320
pF1KB7 TPS--SYPSLSE--VFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEK
.:. : :::. . ::.::::::::::.:..::: : : ::.:::: .::::: :::
XP_016 SPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEK
380 390 400 410 420 430
330 340 350 360 370
pF1KB7 EVVRVWFCNRRQKEKRIN-CPVA----TPIKPPVYNSRLVSPSGSLGPLSVPPVHSTMPG
::.::::::::::::::: : .: .: :: :. ..:.:.:. : : . . :..
XP_016 EVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLST
440 450 460 470 480 490
380 390 400 410 420 430
pF1KB7 TVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAVNSA--SSFNSSGSWYRWNHSTYL
:::. : .. .:: ..: ... .: :: .:. .. ::.. . .::
XP_016 TVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIG
500 510 520 530 540 550
pF1KB7 H
XP_016 LSGLNPSTGSTMVGLSSGLSPALMSNNPLATIQALASGGTLPLTSLDGSGNLVLGAAGAA
560 570 580 590 600 610
436 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:34:25 2016 done: Sat Nov 5 23:34:27 2016
Total Scan time: 10.830 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]