Result of FASTA (omim) for
pFN21AB7704
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7704, 462 aa
1>>>pF1KB7704 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0632+/-0.000477; mu= -9.0793+/- 0.030
mean_var=309.1133+/-62.449, 0's: 0 Z-trim(119.4): 10 B-trim: 340 in 1/56
Lambda= 0.072948
statistics sampled from 33435 (33445) to 33435 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.392), width: 16
Scan time: 8.830
The best scores are: opt bits E(85289)
NP_079161 (OMIM: 300314) transcription initiation ( 462) 2984 327.7 4e-89
XP_006724727 (OMIM: 300314) PREDICTED: transcripti ( 463) 2972 326.5 9.6e-89
NP_001161946 (OMIM: 300314) transcription initiati ( 376) 2439 270.3 6.2e-72
XP_005262209 (OMIM: 300314) PREDICTED: transcripti ( 377) 2427 269.1 1.5e-71
NP_005633 (OMIM: 600573) transcription initiation ( 349) 726 90.0 1.1e-17
>>NP_079161 (OMIM: 300314) transcription initiation fact (462 aa)
initn: 2984 init1: 2984 opt: 2984 Z-score: 1721.1 bits: 327.7 E(85289): 4e-89
Smith-Waterman score: 2984; 99.8% identity (99.8% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KB7 MECPEGQLPISSENDSTPTVSTSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPAD
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_079 MECPEGQLPISSENDSTPTVSTSEVTSQQEPQILVDRGSETTYESSADIAGDEGTQIPAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIM
370 380 390 400 410 420
430 440 450 460
pF1KB7 KVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
::::::::::::::::::::::::::::::::::::::::::
NP_079 KVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
430 440 450 460
>>XP_006724727 (OMIM: 300314) PREDICTED: transcription i (463 aa)
initn: 2428 init1: 2124 opt: 2972 Z-score: 1714.2 bits: 326.5 E(85289): 9.6e-89
Smith-Waterman score: 2972; 99.6% identity (99.6% similar) in 463 aa overlap (1-462:1-463)
10 20 30 40 50 60
pF1KB7 MECPEGQLPISSENDSTPTVSTSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPAD
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_006 MECPEGQLPISSENDSTPTVSTSEVTSQQEPQILVDRGSETTYESSADIAGDEGTQIPAD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGSIPGF
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 LISSGMSSHKQGHTSS-EYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEE
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_006 LISSGMSSHKQGHTSSVEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLI
370 380 390 400 410 420
420 430 440 450 460
pF1KB7 MKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
:::::::::::::::::::::::::::::::::::::::::::
XP_006 MKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
430 440 450 460
>>NP_001161946 (OMIM: 300314) transcription initiation f (376 aa)
initn: 2439 init1: 2439 opt: 2439 Z-score: 1412.4 bits: 270.3 E(85289): 6.2e-72
Smith-Waterman score: 2439; 100.0% identity (100.0% similar) in 376 aa overlap (87-462:1-376)
60 70 80 90 100 110
pF1KB7 IPADEDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRN
::::::::::::::::::::::::::::::
NP_001 MSESQDEVPDEVENQFILRLPLEHACTVRN
10 20 30
120 130 140 150 160 170
pF1KB7 LARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTAD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 ISQMLVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISQMLVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 TQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGS
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB7 IPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKE
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB7 EEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQK
280 290 300 310 320 330
420 430 440 450 460
pF1KB7 DLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
340 350 360 370
>>XP_005262209 (OMIM: 300314) PREDICTED: transcription i (377 aa)
initn: 1883 init1: 1579 opt: 2427 Z-score: 1405.6 bits: 269.1 E(85289): 1.5e-71
Smith-Waterman score: 2427; 99.7% identity (99.7% similar) in 377 aa overlap (87-462:1-377)
60 70 80 90 100 110
pF1KB7 IPADEDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRN
::::::::::::::::::::::::::::::
XP_005 MSESQDEVPDEVENQFILRLPLEHACTVRN
10 20 30
120 130 140 150 160 170
pF1KB7 LARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTAD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 ISQMLVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISQMLVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 TQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGS
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB7 IPGFLISSGMSSHKQGHTSS-EYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDK
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 IPGFLISSGMSSHKQGHTSSVEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB7 EEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQ
280 290 300 310 320 330
420 430 440 450 460
pF1KB7 KDLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
340 350 360 370
>>NP_005633 (OMIM: 600573) transcription initiation fact (349 aa)
initn: 1213 init1: 669 opt: 726 Z-score: 438.6 bits: 90.0 E(85289): 1.1e-17
Smith-Waterman score: 1288; 57.1% identity (79.1% similar) in 378 aa overlap (87-462:1-349)
60 70 80 90 100 110
pF1KB7 IPADEDTQTDADSSAQAAAQAPENFQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRN
::.:.:..: :.:.::::::: :.: :::
NP_005 MSKSKDDAPHELESQFILRLPPEYASTVRR
10 20 30
120 130 140 150 160 170
pF1KB7 LARSQSVKMKDKLKIDLLPDGRHAVVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTAD
..: :..::.: :.: :::::..:.:. ::::.::::::::.:::.:.::::::::::
NP_005 AVQSGHVNLKDRLTIELHPDGRHGIVRVDRVPLASKLVDLPCVMESLKTIDKKTFYKTAD
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 ISQMLVCTADGDIHLSPEEPAASTDPNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRK
: :::: :.:::.. :::.:::::. .::.. .:.: .:.:::: :::::::.::::
NP_005 ICQMLVSTVDGDLYPPVEEPVASTDPKASKKKDKDKEKKFIWNHGITLPLKNVRKRRFRK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 TQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQGS
: :: .::::::::.:::::: .::::::::::.:::: ::: :.::
NP_005 TAKK-------------KYIESPDVEKEVKRLLSTDAEAVSTRWEIIAEDETKEAENQG-
160 170 180 190
300 310 320 330 340 350
pF1KB7 IPGFLISS-GMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDK
. ::: :::.:.::: : :.: :::.:.: :.. .:::: . .:: :: .
NP_005 ---LDISSPGMSGHRQGHDSLEHDELREIFNDLSSSS------EDEDETQHQDE-EDINI
200 210 220 230 240
360 370 380 390 400 410
pF1KB7 EEEEEDCSEEYLERQLQAEFIESG-QYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQR
. ::: :::::: .. :: :.. ::::...:: :::::.. . ::.. :..:.:
NP_005 IDTEED-----LERQLQDKLNESDEQHQENEGTNQLVMGIQKQIDNMKGKLQETQDRAKR
250 260 270 280 290 300
420 430 440 450 460
pF1KB7 QKDLIMKVENLTLKNHFQSVLEQLELQEKQKNEKLISLQEQLQRFLKK
:.:::::::::.:::.::.::..:. .: ...:.: ::::.:. .:.:
NP_005 QEDLIMKVENLALKNRFQAVLDELKQKEDREKEQLSSLQEELESLLEK
310 320 330 340
462 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:03:35 2016 done: Mon Nov 7 17:03:36 2016
Total Scan time: 8.830 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]