Result of FASTA (omim) for
pFN21AB7696
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7696, 414 aa
1>>>pF1KB7696 414 - 414 aa - 414 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0030+/-0.00038; mu= -1.0004+/- 0.024
mean_var=305.0044+/-62.247, 0's: 0 Z-trim(123.6): 394 B-trim: 225 in 2/53
Lambda= 0.073438
statistics sampled from 43391 (43791) to 43391 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.513), width: 16
Scan time: 6.840
The best scores are: opt bits E(85289)
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 2871 317.1 5.2e-86
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 2459 273.4 7.3e-73
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 1781 201.4 2.3e-51
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 1740 197.1 4.4e-50
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 1740 197.1 4.4e-50
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 1707 193.6 5.1e-49
NP_005225 (OMIM: 132880) nuclear receptor subfamil ( 404) 1200 140.0 1e-32
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 1001 119.0 2.4e-26
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 1001 119.0 2.5e-26
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 978 116.6 1.5e-25
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 975 116.2 1.5e-25
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 976 116.3 1.5e-25
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 975 116.3 1.9e-25
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 967 115.3 2.5e-25
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 958 114.3 4.6e-25
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 958 114.3 4.6e-25
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 956 114.2 6.2e-25
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 950 113.6 1e-24
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 925 110.8 5.3e-24
NP_001274111 (OMIM: 125850,125853,600281,616026) h ( 439) 798 97.5 7.1e-20
NP_001274112 (OMIM: 125850,125853,600281,616026) h ( 449) 798 97.5 7.2e-20
NP_001245284 (OMIM: 125850,125853,600281,616026) h ( 467) 789 96.5 1.4e-19
NP_001025174 (OMIM: 125850,125853,600281,616026) h ( 442) 788 96.4 1.5e-19
NP_787110 (OMIM: 125850,125853,600281,616026) hepa ( 452) 788 96.4 1.5e-19
XP_005260464 (OMIM: 125850,125853,600281,616026) P ( 513) 789 96.6 1.5e-19
NP_001274113 (OMIM: 125850,125853,600281,616026) h ( 392) 786 96.2 1.6e-19
NP_849180 (OMIM: 125850,125853,600281,616026) hepa ( 464) 787 96.3 1.6e-19
NP_000448 (OMIM: 125850,125853,600281,616026) hepa ( 474) 787 96.3 1.7e-19
NP_001025175 (OMIM: 125850,125853,600281,616026) h ( 395) 776 95.1 3.3e-19
NP_849181 (OMIM: 125850,125853,600281,616026) hepa ( 417) 775 95.0 3.7e-19
XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 773 94.8 4.2e-19
XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 773 94.8 4.2e-19
XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 773 94.8 4.2e-19
NP_001317490 (OMIM: 605966) hepatocyte nuclear fac ( 408) 773 94.8 4.2e-19
XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 773 94.8 4.2e-19
NP_004124 (OMIM: 605966) hepatocyte nuclear factor ( 445) 773 94.8 4.5e-19
XP_016876575 (OMIM: 602167,608565) PREDICTED: ster ( 508) 678 84.8 5.3e-16
NP_004443 (OMIM: 602167,608565) steroid hormone re ( 508) 678 84.8 5.3e-16
XP_011534856 (OMIM: 602167,608565) PREDICTED: ster ( 529) 678 84.8 5.4e-16
XP_011534855 (OMIM: 602167,608565) PREDICTED: ster ( 531) 678 84.8 5.5e-16
XP_011534852 (OMIM: 602167,608565) PREDICTED: ster ( 552) 678 84.8 5.6e-16
XP_016876574 (OMIM: 602167,608565) PREDICTED: ster ( 552) 678 84.8 5.6e-16
XP_011534849 (OMIM: 602167,608565) PREDICTED: ster ( 573) 678 84.9 5.8e-16
XP_016856137 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 669 83.8 9.1e-16
NP_001230442 (OMIM: 602969) estrogen-related recep ( 435) 669 83.8 9.1e-16
XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 669 83.8 9.1e-16
NP_001230440 (OMIM: 602969) estrogen-related recep ( 435) 669 83.8 9.1e-16
XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 669 83.8 9.1e-16
XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 669 83.8 9.1e-16
NP_001127757 (OMIM: 602969) estrogen-related recep ( 435) 669 83.8 9.1e-16
>>NP_066285 (OMIM: 107773,615779) COUP transcription fac (414 aa)
initn: 2871 init1: 2871 opt: 2871 Z-score: 1665.2 bits: 317.1 E(85289): 5.2e-86
Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414)
10 20 30 40 50 60
pF1KB7 MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 CPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 CPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 QVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRF
310 320 330 340 350 360
370 380 390 400 410
pF1KB7 GKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
370 380 390 400 410
>>NP_005645 (OMIM: 132890,615722) COUP transcription fac (423 aa)
initn: 2398 init1: 2271 opt: 2459 Z-score: 1429.1 bits: 273.4 E(85289): 7.3e-73
Smith-Waterman score: 2459; 85.9% identity (91.1% similar) in 426 aa overlap (1-414:1-421)
10 20 30 40
pF1KB7 MAMVVSTWRDPQDEVPGSQG---SQASQAPPVPG---------PPPGAPHTPQTPGQGGP
::::::.::::::.: :.. . :.:: : ::::::::::: :
NP_005 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 ASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR
.::. .. ::: ::. :.:::::::::::::::::::::::::::::::::::
NP_005 PATPGTAGDKGQGPPGS-----GQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 RNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTN
:::.:::::::::::::::::::::::::::::::::::::::::::::::. ::.::::
NP_005 RNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTN
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 GDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWAR
::::: : :::::::::::::::::::.::::::::::::::::::::::.:::::::::
NP_005 GDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWAR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 NIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_005 NIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEY
::::::::::::::::::::::::::::::::::::::::::.::.::::::::::::::
NP_005 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEY
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB7 VRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNW
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNW
360 370 380 390 400 410
410
pF1KB7 PYMAIQ
:::.::
NP_005 PYMSIQCS
420
>>NP_001138627 (OMIM: 107773,615779) COUP transcription (281 aa)
initn: 1779 init1: 1779 opt: 1781 Z-score: 1043.3 bits: 201.4 E(85289): 2.3e-51
Smith-Waterman score: 1781; 97.8% identity (98.2% similar) in 275 aa overlap (140-414:7-281)
110 120 130 140 150 160
pF1KB7 NLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNG
:. : ::::::::::::::::::::::
NP_001 MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNG
10 20 30
170 180 190 200 210 220
pF1KB7 DPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARN
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB7 IPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFM
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB7 DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYV
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB7 RSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP
220 230 240 250 260 270
410
pF1KB7 YMAIQ
:::::
NP_001 YMAIQ
280
>>NP_001138629 (OMIM: 107773,615779) COUP transcription (261 aa)
initn: 1740 init1: 1740 opt: 1740 Z-score: 1020.2 bits: 197.1 E(85289): 4.4e-50
Smith-Waterman score: 1740; 100.0% identity (100.0% similar) in 261 aa overlap (154-414:1-261)
130 140 150 160 170 180
pF1KB7 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYIS
::::::::::::::::::::::::::::::
NP_001 MPPTQPTHGQFALTNGDPLNCHSYLSGYIS
10 20 30
190 200 210 220 230 240
pF1KB7 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB7 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB7 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
160 170 180 190 200 210
370 380 390 400 410
pF1KB7 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
220 230 240 250 260
>>NP_001138628 (OMIM: 107773,615779) COUP transcription (261 aa)
initn: 1740 init1: 1740 opt: 1740 Z-score: 1020.2 bits: 197.1 E(85289): 4.4e-50
Smith-Waterman score: 1740; 100.0% identity (100.0% similar) in 261 aa overlap (154-414:1-261)
130 140 150 160 170 180
pF1KB7 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYIS
::::::::::::::::::::::::::::::
NP_001 MPPTQPTHGQFALTNGDPLNCHSYLSGYIS
10 20 30
190 200 210 220 230 240
pF1KB7 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB7 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB7 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
160 170 180 190 200 210
370 380 390 400 410
pF1KB7 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
220 230 240 250 260
>>XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP tra (273 aa)
initn: 1707 init1: 1707 opt: 1707 Z-score: 1001.1 bits: 193.6 E(85289): 5.1e-49
Smith-Waterman score: 1707; 95.1% identity (98.9% similar) in 267 aa overlap (148-414:5-271)
120 130 140 150 160 170
pF1KB7 NRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSY
.:::::::::::. ::.::::::::: : :
XP_016 MFGYSVQRGRMPPTQPNPGQYALTNGDPLNGHCY
10 20 30
180 190 200 210 220 230
pF1KB7 LSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQ
::::::::::::::::::.::::::::::::::::::::::.::::::::::::::::::
XP_016 LSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQ
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB7 ITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB7 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQP
:::::::::::::::::::::::::::::::::.::.:::::::::::::::::::::::
XP_016 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQP
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB7 TRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_016 SRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
220 230 240 250 260 270
>>NP_005225 (OMIM: 132880) nuclear receptor subfamily 2 (404 aa)
initn: 1725 init1: 1111 opt: 1200 Z-score: 708.5 bits: 140.0 E(85289): 1e-32
Smith-Waterman score: 1701; 64.2% identity (81.5% similar) in 400 aa overlap (31-414:9-404)
10 20 30 40 50
pF1KB7 MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAG-G
: : : . . : : : .. ..:. :
NP_005 MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG
10 20 30
60 70 80 90 100 110
pF1KB7 QGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANR
.. . :: :... ...:::::::::::::: :::::::::::::.:::::::::.::
NP_005 AASDAEPG-DEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNR
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 NCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDP--------
.: :::::::::::::::::..::::.:::::::.: . : : : ..:.:
NP_005 DCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLP--GAVAASSGSPPGSALAAV
100 110 120 130 140 150
180 190 200 210 220
pF1KB7 -----LNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFSAV
: . .: :. ::::::::.. :::. . ..::.:.::::::.:::.:
NP_005 ASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTV
160 170 180 190 200 210
230 240 250 260 270 280
pF1KB7 EWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR
::::. ::::.: ..::::::::.::::::::::: ..:::.:::::::::::.::.:.:
NP_005 EWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAER
220 230 240 250 260 270
290 300 310 320 330 340
pF1KB7 VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCA
.:::::..: :::::.:: :.::::::.:::::.::: ::::::: :::::::::.: :
NP_005 AVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVA
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB7 LEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGS
: ::::.:::.:: :::.::::::.::.: .:.: ::::.::::::::::::::::::::
NP_005 LTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGS
340 350 360 370 380 390
410
pF1KB7 SFNWPYMAIQ
.::::: . :
NP_005 TFNWPYGSGQ
400
>>NP_001278849 (OMIM: 180245) retinoic acid receptor RXR (435 aa)
initn: 566 init1: 532 opt: 1001 Z-score: 594.1 bits: 119.0 E(85289): 2.4e-26
Smith-Waterman score: 1001; 39.9% identity (70.6% similar) in 398 aa overlap (11-400:37-428)
10 20 30
pF1KB7 MAMVVSTWRDPQDEVPGSQGSQASQAPPVP--GPPPGAPH
: . . . .: .. ..: .: : :.:.
NP_001 HPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 --TPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTC
.:..: ... : : :. :... . .:: :..:::.::::::: ..:
NP_001 LSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHI-CAICGDRSSGKHYGVYSC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB7 EGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPP
::::.::::.::..:.:::: :..: ::...::.::::: .::: .::.:::::. :.
NP_001 EGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB7 TQPTHGQFALTNG--DPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICE
. .... :.. . . . : . ... ..: : . .: . .::. . :::.
NP_001 KDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPND--PVTNICQ
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB7 LAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAG
: ..::. ::::. :: : .: . ::: ::: :.::.. . .. :. .. . :::. :
NP_001 AADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLAT-G
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 LHASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVA
::. :: : :..: :.. : : :.. ...:..: .::.:::::. :. :::. :
NP_001 LHVHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB7 HVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPI
.::.:.:: .:: : . .::.:: ::.:::::::.::... . .:.::: .:.: :::
NP_001 EVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPI
370 380 390 400 410 420
400 410
pF1KB7 ETLIRDMLLSGSSFNWPYMAIQ
.:.. .::
NP_001 DTFLMEMLEAPHQMT
430
>>NP_002948 (OMIM: 180245) retinoic acid receptor RXR-al (462 aa)
initn: 566 init1: 532 opt: 1001 Z-score: 593.8 bits: 119.0 E(85289): 2.5e-26
Smith-Waterman score: 1001; 39.9% identity (70.6% similar) in 398 aa overlap (11-400:64-455)
10 20 30
pF1KB7 MAMVVSTWRDPQDEVPGSQGSQASQAPPVP--GPPPGAPH
: . . . .: .. ..: .: : :.:.
NP_002 HPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB7 --TPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTC
.:..: ... : : :. :... . .:: :..:::.::::::: ..:
NP_002 LSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHI-CAICGDRSSGKHYGVYSC
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB7 EGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPP
::::.::::.::..:.:::: :..: ::...::.::::: .::: .::.:::::. :.
NP_002 EGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB7 TQPTHGQFALTNG--DPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICE
. .... :.. . . . : . ... ..: : . .: . .::. . :::.
NP_002 KDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPND--PVTNICQ
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB7 LAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAG
: ..::. ::::. :: : .: . ::: ::: :.::.. . .. :. .. . :::. :
NP_002 AADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLAT-G
280 290 300 310 320
280 290 300 310 320 330
pF1KB7 LHASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVA
::. :: : :..: :.. : : :.. ...:..: .::.:::::. :. :::. :
NP_002 LHVHRNSAHSAGVGAIFD--RVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPA
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB7 HVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPI
.::.:.:: .:: : . .::.:: ::.:::::::.::... . .:.::: .:.: :::
NP_002 EVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPI
390 400 410 420 430 440
400 410
pF1KB7 ETLIRDMLLSGSSFNWPYMAIQ
.:.. .::
NP_002 DTFLMEMLEAPHQMT
450 460
>>NP_068811 (OMIM: 180246) retinoic acid receptor RXR-be (533 aa)
initn: 733 init1: 630 opt: 978 Z-score: 579.8 bits: 116.6 E(85289): 1.5e-25
Smith-Waterman score: 999; 38.8% identity (64.2% similar) in 433 aa overlap (11-400:106-526)
10 20 30
pF1KB7 MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHT-
: . .:. :: : ::.: :: :.:
NP_068 SGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPV
80 90 100 110 120 130
40 50 60
pF1KB7 ------------PQTPGQGGPASTP-----AQTAAGGQGGP-------------------
: :: .::.:.: .. .::.: :
NP_068 ISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPP
140 150 160 170 180 190
70 80 90 100 110 120
pF1KB7 GGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPI
::::. :. :..:::.::::::: ..:::::.::::..:..:.:.:: :..: .
NP_068 GGPGAGKRL------CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTV
200 210 220 230 240
130 140 150 160 170 180
pF1KB7 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRM-PPTQPTHGQFALTNGDPLNCHSYLSGYI
:...::.::::: .::: .::.:::::. :. . :. : . . : . .
NP_068 DKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAEL
250 260 270 280 290 300
190 200 210 220 230
pF1KB7 SLLLRAEPY---PTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQIT
.. ... : . :: .::. . :::. : ..::. ::::. :: : .: .
NP_068 AVEQKSDQGVEGPGGTGGSGS-SPND--PVTNICQAADKQLFTLVEWAKRIPHFSSLPLD
310 320 330 340 350 360
240 250 260 270 280 290
pF1KB7 DQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR--VVAFMDHIRIFQE
::: ::: :.::.. . .. :. .. . :::. :::. :: : :..: :.. :
NP_068 DQVILLRAGWNELLIASFSHRSIDVRDGILLAT-GLHVHRNSAHSAGVGAIFD--RVLTE
370 380 390 400 410 420
300 310 320 330 340 350
pF1KB7 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQP
: :.. ...:..: .::.::.::. :: :::. ..:: :.:: .:: : ...::.:
NP_068 LVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQ
430 440 450 460 470 480
360 370 380 390 400 410
pF1KB7 TRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
::.:::::::.::... . .:.::: .:.: :::.:.. .::
NP_068 GRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
490 500 510 520 530
414 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:24:15 2016 done: Sun Nov 6 21:24:17 2016
Total Scan time: 6.840 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]