FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7678, 406 aa
  1>>>pF1KB7678 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 16.1488+/-0.000566; mu= -29.6122+/- 0.036
 mean_var=931.7234+/-190.255, 0's: 0 Z-trim(124.3): 192  B-trim: 880 in 1/59
 Lambda= 0.042018
 statistics sampled from 45480 (45787) to 45480 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.537), width:  16
 Scan time: 10.900

The best scores are:                                      opt bits E(85289)
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 2970 195.0 2.8e-49
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346)  424 40.6  0.0072


>>NP_703149 (OMIM: 300154) homeobox protein ESX1 [Homo s  (406 aa)
 initn: 2970 init1: 2970 opt: 2970  Z-score: 1005.8  bits: 195.0 E(85289): 2.8e-49
Smith-Waterman score: 2970; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)

               10        20        30        40        50        60
pF1KB7 MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_703 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG
              310       320       330       340       350       360

              370       380       390       400      
pF1KB7 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_703 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF
              370       380       390       400      

>>NP_038463 (OMIM: 601881,611038) retinal homeobox prote  (346 aa)
 initn: 431 init1: 296 opt: 424  Z-score: 172.5  bits: 40.6 E(85289): 0.0072
Smith-Waterman score: 440; 31.5% identity (48.9% similar) in 321 aa overlap (65-371:56-320)

           40        50        60        70            80          
pF1KB7 SLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGG----GHEPEQQQEE--
                                     :.  . ..::. :.     . ::. .:   
NP_038 GGSTSRLHSIEAILGFTKDDGILGTFPAERGARGAKERDRRLGARPACPKAPEEGSEPSP
          30        40        50        60        70        80     

       90       100        110       120       130       140       
pF1KB7 PPLTKPEQQQEEP-PLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFT
       ::   :  . : : :    .  . .:      ::  .:. . .:  :: ...:: ::.::
NP_038 PPAPAPAPEYEAPRPYCPKEPGEARPSPGLPVGPATGEA-KLSEEEQPKKKHRRNRTTFT
          90       100       110       120        130       140    

       150       160       170       180       190       200       
pF1KB7 QFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTA
        .::.:::  :..:.:::: .::.::...:: : :::::::::::::.:... : . .  
NP_038 TYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK-LEVSSMK
          150       160       170       180       190        200   

       210       220       230       240       250       260       
pF1KB7 TADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPI
         :                                              :.. .   :: 
NP_038 LQD---------------------------------------------SPLLSFSRSPPS
                                                        210        

       270       280       290         300       310        320    
pF1KB7 APMPPMAPVPPGSRMAPVPPGPRMAPVPPW--PPMAPVPPWPPMAPVPT-GPPMAPVPPG
       : . :.. . :::  .:.  :  . :.  :  ::. :      .  .:  :::   .: .
NP_038 ATLSPLG-AGPGSGGGPA--GGAL-PLESWLGPPL-PGGGATALQSLPGFGPPAQSLPAS
      220        230          240        250       260       270   

            330       340        350       360        370       380
pF1KB7 --PPMARVPPGPPMARVPP-GPPMAPLPPGPPMAPLPPG-PPMAPLPPGPPMAPLPPRSH
         ::    :: ::.   :: :: . :: : ::  :  ::     ::  . :         
NP_038 YTPP----PPPPPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALR
               280       290       300       310       320         

              390       400      
pF1KB7 VPHTGLAPVHITWAPVINSYYACPFF
                                 
NP_038 LKAKEHIQAIGKPWQAL         
     330       340               




406 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 07:19:41 2016 done: Thu Nov  3 07:19:42 2016
 Total Scan time: 10.900 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]