Result of FASTA (omim) for
pFN21AB7616
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7616, 361 aa
1>>>pF1KB7616 361 - 361 aa - 361 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6033+/-0.000313; mu= 12.9692+/- 0.020
mean_var=158.0278+/-31.882, 0's: 0 Z-trim(121.1): 287 B-trim: 112 in 2/58
Lambda= 0.102025
statistics sampled from 36796 (37166) to 36796 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.436), width: 16
Scan time: 8.380
The best scores are: opt bits E(85289)
NP_878314 (OMIM: 142993,610092,610093) visual syst ( 361) 2387 362.7 7.1e-100
NP_055403 (OMIM: 122000,148300,605020,614195) visu ( 365) 764 123.8 5.9e-28
XP_016883326 (OMIM: 122000,148300,605020,614195) P ( 280) 697 113.9 4.6e-25
NP_001243201 (OMIM: 122000,148300,605020,614195) v ( 301) 697 113.9 4.8e-25
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 396 69.7 1.3e-11
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 357 63.9 6.1e-10
NP_955457 (OMIM: 122000,148300,605020,614195) visu ( 239) 343 61.7 2e-09
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 341 61.4 2.4e-09
NP_008913 (OMIM: 601527,613456) ALX homeobox prote ( 326) 341 61.5 3e-09
XP_016883327 (OMIM: 122000,148300,605020,614195) P ( 218) 338 60.9 3.1e-09
NP_001243200 (OMIM: 122000,148300,605020,614195) v ( 236) 338 60.9 3.3e-09
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 343 62.1 3.5e-09
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 329 59.8 1.1e-08
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 324 58.9 1.3e-08
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325) 326 59.3 1.4e-08
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 322 58.5 1.4e-08
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 323 59.0 2.1e-08
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 323 59.0 2.1e-08
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 323 59.0 2.1e-08
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 323 59.0 2.1e-08
NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 318 58.1 2.9e-08
NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 318 58.1 2.9e-08
NP_001297088 (OMIM: 106210,120430,136520,148190,16 ( 401) 318 58.2 3.6e-08
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 318 58.3 3.7e-08
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 318 58.3 3.7e-08
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 318 58.3 3.7e-08
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 318 58.3 3.7e-08
NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436) 318 58.3 3.8e-08
NP_001297087 (OMIM: 106210,120430,136520,148190,16 ( 436) 318 58.3 3.8e-08
NP_001245392 (OMIM: 106210,120430,136520,148190,16 ( 436) 318 58.3 3.8e-08
NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436) 318 58.3 3.8e-08
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 311 57.1 5.8e-08
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 311 57.1 6.3e-08
NP_008833 (OMIM: 167420,202650) paired mesoderm ho ( 217) 298 55.0 1.8e-07
NP_073207 (OMIM: 167420,202650) paired mesoderm ho ( 245) 298 55.1 2e-07
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 301 55.9 2.4e-07
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 301 55.9 2.4e-07
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 301 55.9 2.4e-07
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 296 54.8 2.6e-07
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 297 55.2 3.1e-07
NP_776248 (OMIM: 138890,602471) homeobox protein g ( 257) 294 54.5 3.1e-07
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 297 55.2 3.1e-07
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 297 55.2 3.5e-07
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 297 55.2 3.5e-07
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 297 55.2 3.5e-07
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 297 55.3 3.6e-07
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 290 53.8 3.8e-07
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317) 291 54.2 4.8e-07
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317) 291 54.2 4.8e-07
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317) 291 54.2 4.8e-07
>>NP_878314 (OMIM: 142993,610092,610093) visual system h (361 aa)
initn: 2387 init1: 2387 opt: 2387 Z-score: 1914.1 bits: 362.7 E(85289): 7.1e-100
Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KB7 MTGKAGEALSKPKSETVAKSTSGGAPARCTGFGIQEILGLNKEPPSSHPRAALDGLAPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 MTGKAGEALSKPKSETVAKSTSGGAPARCTGFGIQEILGLNKEPPSSHPRAALDGLAPGH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LLAARSVLSPAGVGGMGLLGPGGLPGFYTQPTFLEVLSDPQSVHLQPLGRASGPLDTSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 LLAARSVLSPAGVGGMGLLGPGGLPGFYTQPTFLEVLSDPQSVHLQPLGRASGPLDTSQT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 ASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 LAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPKLDKMEQDERGPDAQAAISQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 KDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPKLDKMEQDERGPDAQAAISQEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKPEEEEAMDEDRPAERLSPPQLEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_878 LRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKPEEEEAMDEDRPAERLSPPQLEDM
310 320 330 340 350 360
pF1KB7 A
:
NP_878 A
>>NP_055403 (OMIM: 122000,148300,605020,614195) visual s (365 aa)
initn: 776 init1: 701 opt: 764 Z-score: 622.9 bits: 123.8 E(85289): 5.9e-28
Smith-Waterman score: 816; 46.1% identity (65.3% similar) in 369 aa overlap (1-337:1-359)
10 20 30 40 50
pF1KB7 MTGKAGEALSKPKSETVAKSTSGGAP--ARCTGFGIQEILGLNKE-PPSSHPR--AALDG
:::. ..:: .. . : . ::.: .: ::.: ..:::. : : . : .. .:
NP_055 MTGR--DSLSDGRTSSRAL-VPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG
10 20 30 40 50
60 70 80 90 100
pF1KB7 LA----PGHLLAARSVLSPAGVGGMGLL-GPGGLPGFYTQPTFLEVLSD-----PQSVH-
: :: : . :. : :.::: : : : .. : .:.: :.. .
NP_055 PAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL-LLADVPFLPPRGPEP
60 70 80 90 100 110
110 120 130 140 150
pF1KB7 LQPLGRASGP-----LDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQ
::. . : :...:...:: .: ::. : : :::::::::.::..:
NP_055 AAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLK-ASPTLGKRKKRRHRTVFTAHQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 LEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEY
::::::::.::::::::::::::.::::::::::::::::::::::::: :: :::::::
NP_055 LEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEY
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 GLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPK
::::::::: ::::.:.:.::. :.. :::::::::::::. ::: : .. :
NP_055 GLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMI----RKP-GSEDKLAG
240 250 260 270 280 290
280 290 300 310 320
pF1KB7 L---DKME----QDERGPD-AQAAISQEELRENSIAVLRAKAQEHSTKV---LGTVSGPD
: :... :.: : . .. .: :. :. : ..:.... :: :. .: .
NP_055 LWGSDHFKEGSSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSN
300 310 320 330 340 350
330 340 350 360
pF1KB7 SLARSTEKPEEEEAMDEDRPAERLSPPQLEDMA
: : .:
NP_055 STALEGPQPGKVGAT
360
>>XP_016883326 (OMIM: 122000,148300,605020,614195) PREDI (280 aa)
initn: 731 init1: 656 opt: 697 Z-score: 571.0 bits: 113.9 E(85289): 4.6e-25
Smith-Waterman score: 749; 51.5% identity (69.7% similar) in 274 aa overlap (1-253:1-269)
10 20 30 40 50
pF1KB7 MTGKAGEALSKPKSETVAKSTSGGAP--ARCTGFGIQEILGLNKE-PPSSHPR--AALDG
:::. ..:: .. . : . ::.: .: ::.: ..:::. : : . : .. .:
XP_016 MTGR--DSLSDGRTSSRAL-VPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG
10 20 30 40 50
60 70 80 90 100
pF1KB7 LA----PGHLLAARSVLSPAGVGGMGLL-GPGGLPGFYTQPTFLEVLSD-----PQSVH-
: :: : . :. : :.::: : : : .. : .:.: :.. .
XP_016 PAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL-LLADVPFLPPRGPEP
60 70 80 90 100 110
110 120 130 140 150
pF1KB7 LQPLGRASGP-----LDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQ
::. . : :...:...:: .: ::. :.. :::::::::.::..:
XP_016 AAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKAS-PTLGKRKKRRHRTVFTAHQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 LEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEY
::::::::.::::::::::::::.::::::::::::::::::::::::: :: :::::::
XP_016 LEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEY
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 GLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPK
::::::::: ::::.:.:.::. :.. :::::::
XP_016 GLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLLEGETLGCREMK
240 250 260 270 280
280 290 300 310 320 330
pF1KB7 LDKMEQDERGPDAQAAISQEELRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKPEE
>>NP_001243201 (OMIM: 122000,148300,605020,614195) visua (301 aa)
initn: 731 init1: 656 opt: 697 Z-score: 570.6 bits: 113.9 E(85289): 4.8e-25
Smith-Waterman score: 749; 51.5% identity (69.7% similar) in 274 aa overlap (1-253:1-269)
10 20 30 40 50
pF1KB7 MTGKAGEALSKPKSETVAKSTSGGAP--ARCTGFGIQEILGLNKE-PPSSHPR--AALDG
:::. ..:: .. . : . ::.: .: ::.: ..:::. : : . : .. .:
NP_001 MTGR--DSLSDGRTSSRAL-VPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG
10 20 30 40 50
60 70 80 90 100
pF1KB7 LA----PGHLLAARSVLSPAGVGGMGLL-GPGGLPGFYTQPTFLEVLSD-----PQSVH-
: :: : . :. : :.::: : : : .. : .:.: :.. .
NP_001 PAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL-LLADVPFLPPRGPEP
60 70 80 90 100 110
110 120 130 140 150
pF1KB7 LQPLGRASGP-----LDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQ
::. . : :...:...:: .: ::. :.. :::::::::.::..:
NP_001 AAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKAS-PTLGKRKKRRHRTVFTAHQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 LEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEY
::::::::.::::::::::::::.::::::::::::::::::::::::: :: :::::::
NP_001 LEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEY
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 GLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPK
::::::::: ::::.:.:.::. :.. :::::::
NP_001 GLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLLVQTSAPGGSRSLDFAGDTQAPQTPWW
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB7 LDKMEQDERGPDAQAAISQEELRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKPEE
NP_001 CLMTFS
300
>>NP_068745 (OMIM: 605420,609597,613451,615529) homeobox (411 aa)
initn: 452 init1: 355 opt: 396 Z-score: 329.6 bits: 69.7 E(85289): 1.3e-11
Smith-Waterman score: 402; 38.2% identity (61.4% similar) in 220 aa overlap (6-208:58-274)
10 20 30
pF1KB7 MTGKAGEALSKPK----SETVAKSTSGGAPARCT-
:.: :. . .. .: .:: :: .
NP_068 REGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSF
30 40 50 60 70 80
40 50 60 70 80
pF1KB7 -GFGIQEILGLNKEPPSSHPRAALDGLAPG---HLLAARSVLSPAGVGGMGLL-GPGGLP
: : . ::. .:. : :: :.. . :.. : : .:
NP_068 NKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHS
90 100 110 120 130 140
90 100 110 120 130
pF1KB7 GFYTQPTFLE--VLSDPQSVHLQP----LGRASGPLDTSQTASSDSEDVSSSDRKMS-KS
. : . . :..:. : : .: :. :...... . .: .::: ..
NP_068 AALQVPCYAKESSLGEPE---LPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEK
150 160 170 180 190 200
140 150 160 170 180 190
pF1KB7 ALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQN
: ....: ::::.:: :::::::::::.:...:::::::::.:::.:.: : :.::::::
NP_068 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN
210 220 230 240 250 260
200 210 220 230 240 250
pF1KB7 RRAKWRKREKCWGRSSVMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKK
:::::::::.
NP_068 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP
270 280 290 300 310 320
>>NP_006483 (OMIM: 136760,606014) homeobox protein arist (343 aa)
initn: 331 init1: 331 opt: 357 Z-score: 299.5 bits: 63.9 E(85289): 6.1e-10
Smith-Waterman score: 369; 43.6% identity (62.0% similar) in 179 aa overlap (79-243:75-253)
50 60 70 80 90 100
pF1KB7 PRAALDGLAPGHLLAARSVLSPAGVGGMGLLGPG-GLPG--FYTQPTFLEV-LSDPQSVH
:::: .: : :: :. : : :
NP_006 GPRLTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFP
50 60 70 80 90 100
110 120 130 140 150
pF1KB7 LQPLGRASGPLD-TSQTASSDSEDVSSSDRKMSKS---ALNQTK-KRKKRRHRTIFTSYQ
:: .:: : :. .: . ..: .: . ... .: : ::::.:: :...:
NP_006 QLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQ
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB7 LEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCW----GRSSV
::::::.:...:::::::::.::..:.: : :.:::::::::::::::. ::.
NP_006 LEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPF
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB7 MAEYGLYGAMVRHSIP-LPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGER
: : . : : : .:. : .:
NP_006 TAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGF
230 240 250 260 270 280
>>NP_955457 (OMIM: 122000,148300,605020,614195) visual s (239 aa)
initn: 377 init1: 302 opt: 343 Z-score: 290.2 bits: 61.7 E(85289): 2e-09
Smith-Waterman score: 395; 43.3% identity (63.7% similar) in 215 aa overlap (1-194:1-210)
10 20 30 40 50
pF1KB7 MTGKAGEALSKPKSETVAKSTSGGAP--ARCTGFGIQEILGLNKE-PPSSHPR--AALDG
:::. ..:: .. . : . ::.: .: ::.: ..:::. : : . : .. .:
NP_955 MTGR--DSLSDGRTSSRAL-VPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG
10 20 30 40 50
60 70 80 90 100
pF1KB7 LA----PGHLLAARSVLSPAGVGGMGLL-GPGGLPGFYTQPTFLEVLSD-----PQSVH-
: :: : . :. : :.::: : : : .. : .:.: :.. .
NP_955 PAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL-LLADVPFLPPRGPEP
60 70 80 90 100 110
110 120 130 140 150
pF1KB7 LQPLGRASGP-----LDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQ
::. . : :...:...:: .: ::. :.. :::::::::.::..:
NP_955 AAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKAS-PTLGKRKKRRHRTVFTAHQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 LEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEY
::::::::.::::::::::::::.:::::::::::
NP_955 LEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVSGVPFLRSKDTTENVSFPHSVSQSA
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 GLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPK
NP_955 VPSL
>>XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX home (231 aa)
initn: 440 init1: 340 opt: 341 Z-score: 288.8 bits: 61.4 E(85289): 2.4e-09
Smith-Waterman score: 367; 39.4% identity (61.1% similar) in 193 aa overlap (147-320:36-227)
120 130 140 150 160 170
pF1KB7 TSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVY
::::::: ::: :::::::.:...::::::
XP_011 SLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVY
10 20 30 40 50 60
180 190 200 210 220 230
pF1KB7 AREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWG-----RSSVMAEYGLYGAMVRHSIP
.::.::..::: : :.:::::::::::::::. .: .: : : . : :
XP_011 VREQLALRTELTEARVQVWFQNRRAKWRKRER-YGQIQQAKSHFAATYDISVLPRTDSYP
70 80 90 100 110 120
240 250 260 270
pF1KB7 LPESIL--KSAKDG-IMDSCA-PWLLGM------HKKSLEAAAESGRKPEGERQALPK--
.. : .:. : .. :: : . :. ... . . ... . .:
XP_011 QIQNNLWAGNASGGSVVTSCMLPRDTSSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNN
130 140 150 160 170 180
280 290 300 310 320 330
pF1KB7 --LDKMEQDERGPDAQAAISQEELRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKP
:.. . : . . : : .:::::: ::.::....
XP_011 FFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM
190 200 210 220 230
340 350 360
pF1KB7 EEEEAMDEDRPAERLSPPQLEDMA
>>NP_008913 (OMIM: 601527,613456) ALX homeobox protein 1 (326 aa)
initn: 392 init1: 340 opt: 341 Z-score: 287.0 bits: 61.5 E(85289): 3e-09
Smith-Waterman score: 367; 39.4% identity (61.1% similar) in 193 aa overlap (147-320:131-322)
120 130 140 150 160 170
pF1KB7 TSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVY
::::::: ::: :::::::.:...::::::
NP_008 SLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 AREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWG-----RSSVMAEYGLYGAMVRHSIP
.::.::..::: : :.:::::::::::::::. .: .: : : . : :
NP_008 VREQLALRTELTEARVQVWFQNRRAKWRKRER-YGQIQQAKSHFAATYDISVLPRTDSYP
170 180 190 200 210
240 250 260 270
pF1KB7 LPESIL--KSAKDG-IMDSCA-PWLLGM------HKKSLEAAAESGRKPEGERQALPK--
.. : .:. : .. :: : . :. ... . . ... . .:
NP_008 QIQNNLWAGNASGGSVVTSCMLPRDTSSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNN
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB7 --LDKMEQDERGPDAQAAISQEELRENSIAVLRAKAQEHSTKVLGTVSGPDSLARSTEKP
:.. . : . . : : .:::::: ::.::....
NP_008 FFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM
280 290 300 310 320
340 350 360
pF1KB7 EEEEAMDEDRPAERLSPPQLEDMA
>>XP_016883327 (OMIM: 122000,148300,605020,614195) PREDI (218 aa)
initn: 372 init1: 297 opt: 338 Z-score: 286.8 bits: 60.9 E(85289): 3.1e-09
Smith-Waterman score: 390; 43.5% identity (63.1% similar) in 214 aa overlap (1-193:1-209)
10 20 30 40 50
pF1KB7 MTGKAGEALSKPKSETVAKSTSGGAP--ARCTGFGIQEILGLNKE-PPSSHPR--AALDG
:::. ..:: .. . : . ::.: .: ::.: ..:::. : : . : .. .:
XP_016 MTGR--DSLSDGRTSSRAL-VPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEG
10 20 30 40 50
60 70 80 90 100
pF1KB7 LA----PGHLLAARSVLSPAGVGGMGLL-GPGGLPGFYTQPTFLEVLSD-----PQSVH-
: :: : . :. : :.::: : : : .. : .:.: :.. .
XP_016 PAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL-LLADVPFLPPRGPEP
60 70 80 90 100 110
110 120 130 140 150
pF1KB7 LQPLGRASGP-----LDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFTSYQ
::. . : :...:...:: .: ::. : : :::::::::.::..:
XP_016 AAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLK-ASPTLGKRKKRRHRTVFTAHQ
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 LEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVMAEY
::::::::.::::::::::::::.::::::::::
XP_016 LEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQRVRHWAAEK
180 190 200 210
220 230 240 250 260 270
pF1KB7 GLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQALPK
361 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:41:30 2016 done: Sun Nov 6 04:41:31 2016
Total Scan time: 8.380 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]