Result of FASTA (omim) for
pFN21AB7578
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7578, 284 aa
1>>>pF1KB7578 284 - 284 aa - 284 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5092+/-0.000337; mu= 4.1932+/- 0.021
mean_var=307.9603+/-62.857, 0's: 0 Z-trim(125.3): 174 B-trim: 828 in 1/57
Lambda= 0.073085
statistics sampled from 48488 (48723) to 48488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.846), E-opt: 0.2 (0.571), width: 16
Scan time: 9.350
The best scores are: opt bits E(85289)
NP_057254 (OMIM: 604240) T-cell leukemia homeobox ( 284) 1981 221.3 1.7e-57
XP_011538046 (OMIM: 186770) PREDICTED: T-cell leuk ( 342) 1080 126.4 7.4e-29
NP_066305 (OMIM: 604640) T-cell leukemia homeobox ( 291) 1016 119.6 7.1e-27
NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 866 103.8 4.5e-22
XP_011538047 (OMIM: 186770) PREDICTED: T-cell leuk ( 269) 761 92.6 8.4e-19
NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 547 70.1 5.1e-12
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 373 51.7 1.8e-06
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 373 51.7 1.8e-06
NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 ( 367) 326 46.9 6.6e-05
NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 322 46.4 7.3e-05
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 305 44.6 0.00027
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 303 44.5 0.00034
NP_064448 (OMIM: 605211) barH-like 1 homeobox prot ( 327) 302 44.3 0.00035
NP_004088 (OMIM: 600034) homeobox protein EMX1 [Ho ( 290) 298 43.9 0.00044
NP_004089 (OMIM: 269160,600035) homeobox protein E ( 252) 287 42.6 0.0009
NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 285 42.4 0.001
NP_001269359 (OMIM: 607164) transcription factor L ( 198) 280 41.8 0.0013
NP_003308 (OMIM: 118700,188550,600635,610978) home ( 371) 282 42.3 0.0016
NP_001073136 (OMIM: 118700,188550,600635,610978) h ( 401) 282 42.4 0.0017
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 280 42.1 0.0019
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 277 41.9 0.0026
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 277 41.9 0.0026
NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 269 40.9 0.004
NP_006553 (OMIM: 604255) transcription factor LBX1 ( 281) 267 40.6 0.0042
XP_016868632 (OMIM: 610772) PREDICTED: homeobox pr ( 265) 266 40.4 0.0043
NP_001009812 (OMIM: 607164) transcription factor L ( 194) 263 40.0 0.0044
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 263 40.1 0.005
NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 267 40.8 0.0051
NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 259 39.4 0.0052
NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 261 39.9 0.0058
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 261 40.0 0.007
NP_573574 (OMIM: 616253) GS homeobox 2 [Homo sapie ( 304) 258 39.7 0.0084
>>NP_057254 (OMIM: 604240) T-cell leukemia homeobox prot (284 aa)
initn: 1981 init1: 1981 opt: 1981 Z-score: 1153.4 bits: 221.3 E(85289): 1.7e-57
Smith-Waterman score: 1981; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284)
10 20 30 40 50 60
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 MDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALP
190 200 210 220 230 240
250 260 270 280
pF1KB7 RPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
::::::::::::::::::::::::::::::::::::::::::::
NP_057 RPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
250 260 270 280
>>XP_011538046 (OMIM: 186770) PREDICTED: T-cell leukemia (342 aa)
initn: 1090 init1: 933 opt: 1080 Z-score: 639.1 bits: 126.4 E(85289): 7.4e-29
Smith-Waterman score: 1087; 58.1% identity (74.4% similar) in 313 aa overlap (4-282:32-339)
10 20 30
pF1KB7 MEPGMLGPHN-LPHHEPISFGIDQILSGPETPG
: .:: . : : .:. ...: : :
XP_011 EHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGE---YGLGCLVGGAYTYG
10 20 30 40 50
40 50 60 70
pF1KB7 GG---LGLGRGGQG-HGENGAFSGGYHGASGYGPAGSLAPLPGS--------SGVGPGG-
:: . : :: : .: .: :: : .: : : :..:: :: .: ::::
XP_011 GGGSAAATGAGGAGAYGTGGP--GGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGG
60 70 80 90 100 110
80 90 100 110 120
pF1KB7 --------------VIRVPAHRPLPV----PPP-AGGAPAVPGPSGLGGAGGLAGLTFPW
:::::::::: : : : : :.::. .. :...:.::::::
XP_011 GGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPW
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 MDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQK
:.:.::..:::.:.:::::. :::::::::::::::.:::::::.: :. :::.:: :::
XP_011 MESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQK
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 YLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALP
::::::::::::::.:::::::::::::::::::::::::::::..:.:.::.:::.:.
XP_011 YLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQ
240 250 260 270 280 290
250 260 270 280
pF1KB7 RPLRPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLASVV
. : ::: ::::.::::::::::::::..:. :..::...::
XP_011 KSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
300 310 320 330 340
>>NP_066305 (OMIM: 604640) T-cell leukemia homeobox prot (291 aa)
initn: 1063 init1: 770 opt: 1016 Z-score: 603.4 bits: 119.6 E(85289): 7.1e-27
Smith-Waterman score: 1102; 64.1% identity (80.1% similar) in 287 aa overlap (12-280:10-290)
10 20 30 40 50
pF1KB7 MEPGMLGPHNLPH-HEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASG
:: ::::::::::::..:. .. :: .: . :. :: ::.
NP_066 MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPA--PRGPDGASYLGGPPGGRPGATY
10 20 30 40 50
60 70 80 90 100
pF1KB7 YG-PA---GSLAPLP--GSSGVG----PGGVIRVPAHRPLP--VPPPAGGA-PAVPG-PS
. :: : ::. :: .:. :.:::::::::::: :::: .: ::.:. :.
NP_066 PSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPT
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 GLGGAGGLAGLTFPWMDSGRRFAKDRLTAA--LSPFSGTRRIGHPYQNRTPPKRKKPRTS
...:.::.::::.:.:::.:::.::: :.::. ::::::::::::::::::::::
NP_066 ----VSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 FSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAE
::: :. :::.:: :::::::::::::::.:.::::::::::::::::::::::::::::
NP_066 FSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 RHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLAS
:..:.::.:.::.::. . : . :::::::::::::::::::: ::. :: .:..:
NP_066 RQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV
240 250 260 270 280 290
pF1KB7 VV
>>NP_005512 (OMIM: 186770) T-cell leukemia homeobox prot (330 aa)
initn: 1021 init1: 715 opt: 866 Z-score: 517.3 bits: 103.8 E(85289): 4.5e-22
Smith-Waterman score: 1018; 55.2% identity (68.6% similar) in 328 aa overlap (13-282:13-327)
10 20 30 40
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPG----------GGLGLG--------RGGQ
: :::::::::::..:. : : ::: ::
NP_005 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
10 20 30 40 50 60
50 60 70
pF1KB7 GH------GENGAFSGGYHGASGYGPAG-----SLAPLPGS--------SGVGPGG----
: : ::.. : :. : :::: :..:: :: .: ::::
NP_005 GSAAATGAGGAGAYGTGGPGGPG-GPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGS
70 80 90 100 110
80 90 100 110 120
pF1KB7 -----------VIRVPAHRPLPV----PPP-AGGAPAVPGPSGLGGAGGLAGLTFPWMDS
:::::::::: : : : : :.::. .. :...:.:::::::.:
NP_005 SGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMES
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 GRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLA
.::..:::.: :::::::::::.:::::::.: :. :::.:: ::::::
NP_005 NRRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLA
180 190 200 210 220
190 200 210 220 230 240
pF1KB7 SAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPL
:::::::::::.:::::::::::::::::::::::::::::..:.:.::.:::.:. . :
NP_005 SAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSL
230 240 250 260 270 280
250 260 270 280
pF1KB7 RPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLASVV
::: ::::.::::::::::::::..:. :..::...::
NP_005 AQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
290 300 310 320 330
>>XP_011538047 (OMIM: 186770) PREDICTED: T-cell leukemia (269 aa)
initn: 635 init1: 635 opt: 761 Z-score: 458.5 bits: 92.6 E(85289): 8.4e-19
Smith-Waterman score: 768; 55.0% identity (69.8% similar) in 242 aa overlap (4-213:32-269)
10 20 30
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGG
: .:: . . . .:. ...: : ::
XP_011 EHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPAS--RLQDGEYGLGCLVGGAYTYGG
10 20 30 40 50
40 50 60 70
pF1KB7 G---LGLGRGGQG-HGENGAFSGGYHGASGYGPAGSLAPLPGS--------SGVGPGG--
: . : :: : .: .: :: : .: : : :..:: :: .: ::::
XP_011 GGSAAATGAGGAGAYGTGGP--GGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGG
60 70 80 90 100 110
80 90 100 110 120
pF1KB7 -------------VIRVPAHRPLPV----PPP-AGGAPAVPGPSGLGGAGGLAGLTFPWM
:::::::::: : : : : :.::. .. :...:.:::::::
XP_011 GSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 DSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKY
.:.::..:::.:.:::::. :::::::::::::::.:::::::.: :. :::.:: ::::
XP_011 ESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKY
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 LASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPR
:::::::::::::.::::::::::::::::::
XP_011 LASAERAALAKALKMTDAQVKTWFQNRRTKWR
240 250 260
250 260 270 280
pF1KB7 PLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
>>NP_001182446 (OMIM: 186770) T-cell leukemia homeobox p (257 aa)
initn: 580 init1: 423 opt: 547 Z-score: 336.8 bits: 70.1 E(85289): 5.1e-12
Smith-Waterman score: 699; 51.9% identity (62.4% similar) in 258 aa overlap (13-213:13-257)
10 20 30 40
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPG----------GGLGLG--------RGGQ
: :::::::::::..:. : : ::: ::
NP_001 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
10 20 30 40 50 60
50 60 70
pF1KB7 GH------GENGAFSGGYHGASGYGPAG-----SLAPLPGS--------SGVGPGG----
: : ::.. : :. : :::: :..:: :: .: ::::
NP_001 GSAAATGAGGAGAYGTGGPGGPG-GPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGS
70 80 90 100 110
80 90 100 110 120
pF1KB7 -----------VIRVPAHRPLPV----PPP-AGGAPAVPGPSGLGGAGGLAGLTFPWMDS
:::::::::: : : : : :.::. .. :...:.:::::::.:
NP_001 SGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMES
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 GRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLA
.::..:::.: :::::::::::.:::::::.: :. :::.:: ::::::
NP_001 NRRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLA
180 190 200 210 220
190 200 210 220 230 240
pF1KB7 SAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPL
:::::::::::.::::::::::::::::::
NP_001 SAERAALAKALKMTDAQVKTWFQNRRTKWR
230 240 250
>>XP_005269800 (OMIM: 600647) PREDICTED: homeobox protei (273 aa)
initn: 320 init1: 267 opt: 373 Z-score: 237.3 bits: 51.7 E(85289): 1.8e-06
Smith-Waterman score: 374; 36.5% identity (55.5% similar) in 263 aa overlap (18-262:19-262)
10 20 30 40 50
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSG-----PETPGGGLGLGRGGQGHGENGAFSGGY
:: :..::.: :. : : . :. . .:. . :.
XP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 HGASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLA
.. . . : . : : : :.: :.: : :.: : :: .: :::
XP_005 KAPACF--------CPDQHGPKEQG----PKHHP-PIPFPCLGTPK--G-SGGSGPGGLE
70 80 90 100
120 130 140 150 160 170
pF1KB7 GLTF--PWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTP-PKRKKPRTSFSRSQVLE
: : : . :.:: : :: :..: .: .:: :: :::::: .
XP_005 RTPFLSP-SHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQ
110 120 130 140 150 160
180 190 200 210 220
pF1KB7 LERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAER--HRAGR
:: : ..::.:.::: ::..:..:..::::::::::.::.:: . : :: : ...
XP_005 LESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB7 LLLHLQ---QDALPRPLRPPLP-----PDPLCLHNSSLFALQNLQPWAEDNKVASVSGLA
:. . .:. :: :.: : :: .:.: ::
XP_005 TLVSMPLVFRDS--SLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
230 240 250 260 270
pF1KB7 SVV
>>NP_005510 (OMIM: 600647) homeobox protein HMX2 [Homo s (273 aa)
initn: 320 init1: 267 opt: 373 Z-score: 237.3 bits: 51.7 E(85289): 1.8e-06
Smith-Waterman score: 374; 36.5% identity (55.5% similar) in 263 aa overlap (18-262:19-262)
10 20 30 40 50
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSG-----PETPGGGLGLGRGGQGHGENGAFSGGY
:: :..::.: :. : : . :. . .:. . :.
NP_005 MGSKEDAGKGCPAAGGVSSFTIQSILGGGPSEAPREPVGWPARKRSLSVSSEEEEPDDGW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 HGASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLA
.. . . : . : : : :.: :.: : :.: : :: .: :::
NP_005 KAPACF--------CPDQHGPKEQG----PKHHP-PIPFPCLGTPK--G-SGGSGPGGLE
70 80 90 100
120 130 140 150 160 170
pF1KB7 GLTF--PWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTP-PKRKKPRTSFSRSQVLE
: : : . :.:: : :: :..: .: .:: :: :::::: .
NP_005 RTPFLSP-SHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAKKKTRTVFSRSQVYQ
110 120 130 140 150 160
180 190 200 210 220
pF1KB7 LERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAER--HRAGR
:: : ..::.:.::: ::..:..:..::::::::::.::.:: . : :: : ...
NP_005 LESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQLSAELEAANMAHASAQ
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB7 LLLHLQ---QDALPRPLRPPLP-----PDPLCLHNSSLFALQNLQPWAEDNKVASVSGLA
:. . .:. :: :.: : :: .:.: ::
NP_005 TLVSMPLVFRDS--SLLRVPVPRSLAFPAPLYYPGSNLSALPLYNLYNKLDY
230 240 250 260 270
pF1KB7 SVV
>>NP_006159 (OMIM: 602563) homeobox protein Nkx-6.1 [Hom (367 aa)
initn: 317 init1: 247 opt: 326 Z-score: 209.1 bits: 46.9 E(85289): 6.6e-05
Smith-Waterman score: 326; 32.8% identity (58.6% similar) in 256 aa overlap (8-245:87-332)
10 20 30
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETP-GGGLG
:..: : ::..::: : : ..: .
NP_006 SSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATP--HGINDILSRPSMPVASGAA
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB7 LGRGG-QGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGP-GGVIRVPAHRPLPVPP-
: .. .: . ... :.. .::. . :.. : .:: .: .:. : . : : ::
NP_006 LPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPG
120 130 140 150 160 170
100 110 120 130 140
pF1KB7 ----PAGGAPAVPG--PSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGH
:...: :. : :. :. : . . .: . .. . :: : .: .:. . .
NP_006 LYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARL--ACTPHQGSILLDK
180 190 200 210 220 230
150 160 170 180 190 200
pF1KB7 PYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQN
:::. : .:: .:.. ::. : . ::::. ::: :: .: ::..:::.::::
NP_006 D------GKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQN
240 250 260 270 280
210 220 230 240 250
pF1KB7 RRTKWRRQTAEE-------REAERHR-AGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSL
::::::.. : : ...: .: : . ..: .:: :
NP_006 RRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKH
290 300 310 320 330 340
260 270 280
pF1KB7 FALQNLQPWAEDNKVASVSGLASVV
NP_006 KSSSGGGGGLLLHASEPESSS
350 360
>>NP_002720 (OMIM: 604420) hematopoietically-expressed h (270 aa)
initn: 301 init1: 238 opt: 322 Z-score: 208.3 bits: 46.4 E(85289): 7.3e-05
Smith-Waterman score: 322; 36.3% identity (62.6% similar) in 171 aa overlap (56-224:41-204)
30 40 50 60 70 80
pF1KB7 SGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGPGGVIRVPA
: .. :: .: : :.:: .. . :.:.
NP_002 GAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTL-PSPNSSFTSLVSPYRTPV
20 30 40 50 60
90 100 110 120 130 140
pF1KB7 HRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAAL--SPFSGTR
..: :. : . :. .. : ::..: .:. : ..: : : .:. :
NP_002 YEPTPIHPAFSHHSAAALAAAYG-PGGFGGPLYPFP----RTVNDYTHALLRHDPL-GKP
70 80 90 100 110 120
150 160 170 180 190 200
pF1KB7 RIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKT
. :. .: ::: .. :: .:..:::..: ::::. :: ::: :.... ::::
NP_002 LLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKT
130 140 150 160 170 180
210 220 230 240 250 260
pF1KB7 WFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQ
::::::.:::: :. ....
NP_002 WFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQ
190 200 210 220 230 240
284 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:25:16 2016 done: Sun Nov 6 18:25:18 2016
Total Scan time: 9.350 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]