FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7578, 284 aa
  1>>>pF1KB7578 284 - 284 aa - 284 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3897+/-0.000815; mu= 5.0406+/- 0.050
 mean_var=289.6243+/-59.381, 0's: 0 Z-trim(117.7): 146  B-trim: 172 in 1/54
 Lambda= 0.075363
 statistics sampled from 18336 (18493) to 18336 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.841), E-opt: 0.2 (0.568), width:  16
 Scan time:  3.210

The best scores are:                                      opt bits E(32554)
CCDS1947.1 TLX2 gene_id:3196|Hs108|chr2            ( 284) 1981 227.6 7.9e-60
CCDS34288.1 TLX3 gene_id:30012|Hs108|chr5          ( 291) 1016 122.7 3.1e-28
CCDS7510.1 TLX1 gene_id:3195|Hs108|chr10           ( 330)  866 106.5 2.7e-23
CCDS55725.1 TLX1 gene_id:3195|Hs108|chr10          ( 257)  547 71.7 6.3e-13


>>CCDS1947.1 TLX2 gene_id:3196|Hs108|chr2                 (284 aa)
 initn: 1981 init1: 1981 opt: 1981  Z-score: 1187.6  bits: 227.6 E(32554): 7.9e-60
Smith-Waterman score: 1981; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284)

               10        20        30        40        50        60
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MEPGMLGPHNLPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 GPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 MDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 YLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 YLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALP
              190       200       210       220       230       240

              250       260       270       280    
pF1KB7 RPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
       ::::::::::::::::::::::::::::::::::::::::::::
CCDS19 RPLRPPLPPDPLCLHNSSLFALQNLQPWAEDNKVASVSGLASVV
              250       260       270       280    

>>CCDS34288.1 TLX3 gene_id:30012|Hs108|chr5               (291 aa)
 initn: 1063 init1: 770 opt: 1016  Z-score: 620.5  bits: 122.7 E(32554): 3.1e-28
Smith-Waterman score: 1102; 64.1% identity (80.1% similar) in 287 aa overlap (12-280:10-290)

               10         20        30        40        50         
pF1KB7 MEPGMLGPHNLPH-HEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASG
                  :: ::::::::::::..:.  ..     :: .: .  :.  ::  ::. 
CCDS34   MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPA--PRGPDGASYLGGPPGGRPGATY
                 10        20        30          40        50      

      60            70              80        90          100      
pF1KB7 YG-PA---GSLAPLP--GSSGVG----PGGVIRVPAHRPLP--VPPPAGGA-PAVPG-PS
        . ::   :  ::.   :: .:.    :.::::::::::::  ::::  .: ::.:. :.
CCDS34 PSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPT
         60        70        80        90       100       110      

         110       120       130         140       150       160   
pF1KB7 GLGGAGGLAGLTFPWMDSGRRFAKDRLTAA--LSPFSGTRRIGHPYQNRTPPKRKKPRTS
           ...:.::.::::.:.:::.:::.:::  :.::. ::::::::::::::::::::::
CCDS34 ----VSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTS
            120       130       140       150       160       170  

           170       180       190       200       210       220   
pF1KB7 FSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAE
       ::: :. :::.:: :::::::::::::::.:.::::::::::::::::::::::::::::
CCDS34 FSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAE
            180       190       200       210       220       230  

           230       240       250       260       270        280  
pF1KB7 RHRAGRLLLHLQQDALPRPLRPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLAS
       :..:.::.:.::.::. . :   . :::::::::::::::::::: ::. :: .:..:  
CCDS34 RQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV 
            240       250       260       270       280       290  

         
pF1KB7 VV

>>CCDS7510.1 TLX1 gene_id:3195|Hs108|chr10                (330 aa)
 initn: 1021 init1: 715 opt: 866  Z-score: 531.7  bits: 106.5 E(32554): 2.7e-23
Smith-Waterman score: 1018; 55.2% identity (68.6% similar) in 328 aa overlap (13-282:13-327)

               10        20        30                          40  
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPG----------GGLGLG--------RGGQ
                   : :::::::::::..:.  :          :  :::         :: 
CCDS75 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
               10        20        30        40        50        60

                   50        60             70                     
pF1KB7 GH------GENGAFSGGYHGASGYGPAG-----SLAPLPGS--------SGVGPGG----
       :       :  ::.. :  :. : ::::     :..:: ::        .: ::::    
CCDS75 GSAAATGAGGAGAYGTGGPGGPG-GPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGS
               70        80         90       100       110         

                 80        90            100       110       120   
pF1KB7 -----------VIRVPAHRPLPV----PPP-AGGAPAVPGPSGLGGAGGLAGLTFPWMDS
                  ::::::::::      : : : : :.::.  .. :...:.:::::::.:
CCDS75 SGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMES
     120       130       140       150       160       170         

           130       140       150       160       170       180   
pF1KB7 GRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLA
       .::..:::.:            :::::::::::.:::::::.: :. :::.:: ::::::
CCDS75 NRRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLA
     180                   190       200       210       220       

           190       200       210       220       230       240   
pF1KB7 SAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPL
       :::::::::::.:::::::::::::::::::::::::::::..:.:.::.:::.:. . :
CCDS75 SAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSL
       230       240       250       260       270       280       

           250       260       270        280     
pF1KB7 RPPLPPDPLCLHNSSLFALQNLQPWAEDN-KVASVSGLASVV 
         ::: ::::.::::::::::::::..:. :..::...::   
CCDS75 AQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
       290       300       310       320       330

>>CCDS55725.1 TLX1 gene_id:3195|Hs108|chr10               (257 aa)
 initn: 580 init1: 423 opt: 547  Z-score: 345.5  bits: 71.7 E(32554): 6.3e-13
Smith-Waterman score: 699; 51.9% identity (62.4% similar) in 258 aa overlap (13-213:13-257)

               10        20        30                          40  
pF1KB7 MEPGMLGPHNLPHHEPISFGIDQILSGPETPG----------GGLGLG--------RGGQ
                   : :::::::::::..:.  :          :  :::         :: 
CCDS55 MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
               10        20        30        40        50        60

                   50        60             70                     
pF1KB7 GH------GENGAFSGGYHGASGYGPAG-----SLAPLPGS--------SGVGPGG----
       :       :  ::.. :  :. : ::::     :..:: ::        .: ::::    
CCDS55 GSAAATGAGGAGAYGTGGPGGPG-GPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGS
               70        80         90       100       110         

                 80        90            100       110       120   
pF1KB7 -----------VIRVPAHRPLPV----PPP-AGGAPAVPGPSGLGGAGGLAGLTFPWMDS
                  ::::::::::      : : : : :.::.  .. :...:.:::::::.:
CCDS55 SGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMES
     120       130       140       150       160       170         

           130       140       150       160       170       180   
pF1KB7 GRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLA
       .::..:::.:            :::::::::::.:::::::.: :. :::.:: ::::::
CCDS55 NRRYTKDRFT------------GHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLA
     180                   190       200       210       220       

           190       200       210       220       230       240   
pF1KB7 SAERAALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRAGRLLLHLQQDALPRPL
       :::::::::::.::::::::::::::::::                              
CCDS55 SAERAALAKALKMTDAQVKTWFQNRRTKWR                              
       230       240       250                                     




284 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 18:25:15 2016 done: Sun Nov  6 18:25:16 2016
 Total Scan time:  3.210 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]