Result of FASTA (omim) for
pFN21AB7520
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7520, 248 aa
1>>>pF1KB7520 248 - 248 aa - 248 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3322+/-0.000394; mu= 14.5448+/- 0.024
mean_var=66.7062+/-13.638, 0's: 0 Z-trim(111.7): 123 B-trim: 237 in 1/53
Lambda= 0.157033
statistics sampled from 20241 (20367) to 20241 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.239), width: 16
Scan time: 6.260
The best scores are: opt bits E(85289)
NP_689536 (OMIM: 612568) transcription factor Spi- ( 248) 1695 392.9 2.9e-109
XP_006719302 (OMIM: 612568) PREDICTED: transcripti ( 248) 1695 392.9 2.9e-109
XP_005268703 (OMIM: 612568) PREDICTED: transcripti ( 248) 1695 392.9 2.9e-109
XP_011518609 (OMIM: 165170) PREDICTED: transcripti ( 183) 399 99.2 5.4e-21
XP_016873662 (OMIM: 165170) PREDICTED: transcripti ( 183) 399 99.2 5.4e-21
NP_003111 (OMIM: 165170) transcription factor PU.1 ( 270) 399 99.3 7.5e-21
NP_001074016 (OMIM: 165170) transcription factor P ( 271) 399 99.3 7.5e-21
NP_001230927 (OMIM: 606802) transcription factor S ( 171) 378 94.4 1.4e-19
NP_003112 (OMIM: 606802) transcription factor Spi- ( 262) 380 95.0 1.4e-19
NP_001230929 (OMIM: 606802) transcription factor S ( 231) 377 94.2 2.1e-19
NP_001230009 (OMIM: 605169) ETS-related transcript ( 160) 234 61.8 8.7e-10
NP_001230010 (OMIM: 605169) ETS-related transcript ( 187) 225 59.8 4.1e-09
XP_016872798 (OMIM: 605169) PREDICTED: ETS-related ( 232) 223 59.4 6.6e-09
XP_016872797 (OMIM: 605169) PREDICTED: ETS-related ( 238) 223 59.4 6.8e-09
NP_001413 (OMIM: 605169) ETS-related transcription ( 255) 223 59.4 7.2e-09
NP_938195 (OMIM: 605169) ETS-related transcription ( 265) 223 59.4 7.4e-09
XP_016873023 (OMIM: 605439) PREDICTED: ETS homolog ( 298) 217 58.1 2.1e-08
XP_005252919 (OMIM: 605439) PREDICTED: ETS homolog ( 277) 211 56.7 5.1e-08
NP_001193544 (OMIM: 605439) ETS homologous factor ( 277) 211 56.7 5.1e-08
XP_005252918 (OMIM: 605439) PREDICTED: ETS homolog ( 299) 211 56.7 5.4e-08
XP_011518287 (OMIM: 605439) PREDICTED: ETS homolog ( 300) 205 55.3 1.4e-07
XP_005252917 (OMIM: 605439) PREDICTED: ETS homolog ( 300) 205 55.3 1.4e-07
XP_011518286 (OMIM: 605439) PREDICTED: ETS homolog ( 300) 205 55.3 1.4e-07
NP_036285 (OMIM: 605439) ETS homologous factor iso ( 300) 205 55.3 1.4e-07
XP_011518285 (OMIM: 605439) PREDICTED: ETS homolog ( 303) 205 55.3 1.4e-07
XP_005252914 (OMIM: 605439) PREDICTED: ETS homolog ( 321) 205 55.4 1.5e-07
NP_001193545 (OMIM: 605439) ETS homologous factor ( 322) 205 55.4 1.5e-07
NP_001239223 (OMIM: 608144) SAM pointed domain-con ( 319) 203 54.9 2e-07
NP_036523 (OMIM: 608144) SAM pointed domain-contai ( 335) 203 54.9 2.1e-07
XP_005249045 (OMIM: 608144) PREDICTED: SAM pointed ( 407) 203 55.0 2.5e-07
XP_011533253 (OMIM: 189973) PREDICTED: ETS-related ( 560) 203 55.0 3.2e-07
XP_011529610 (OMIM: 300775) PREDICTED: ETS-related ( 586) 203 55.0 3.3e-07
NP_001138825 (OMIM: 189973) ETS-related transcript ( 595) 203 55.0 3.4e-07
XP_011529609 (OMIM: 300775) PREDICTED: ETS-related ( 595) 203 55.0 3.4e-07
XP_005266334 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_011533252 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_016875899 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_005266333 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_016875901 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_016875898 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_016875902 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
XP_016875900 (OMIM: 189973) PREDICTED: ETS-related ( 619) 203 55.1 3.5e-07
NP_758961 (OMIM: 189973) ETS-related transcription ( 619) 203 55.1 3.5e-07
XP_005262446 (OMIM: 300775) PREDICTED: ETS-related ( 663) 203 55.1 3.7e-07
NP_001120669 (OMIM: 300775) ETS-related transcript ( 663) 203 55.1 3.7e-07
NP_001412 (OMIM: 300775) ETS-related transcription ( 663) 203 55.1 3.7e-07
NP_001107781 (OMIM: 602191) ETS-related transcript ( 371) 190 52.0 1.8e-06
NP_004424 (OMIM: 602191) ETS-related transcription ( 371) 190 52.0 1.8e-06
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 188 51.5 1.8e-06
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 188 51.5 2.5e-06
>>NP_689536 (OMIM: 612568) transcription factor Spi-C [H (248 aa)
initn: 1695 init1: 1695 opt: 1695 Z-score: 2082.7 bits: 392.9 E(85289): 2.9e-109
Smith-Waterman score: 1695; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB7 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
190 200 210 220 230 240
pF1KB7 HELNHHDC
::::::::
NP_689 HELNHHDC
>>XP_006719302 (OMIM: 612568) PREDICTED: transcription f (248 aa)
initn: 1695 init1: 1695 opt: 1695 Z-score: 2082.7 bits: 392.9 E(85289): 2.9e-109
Smith-Waterman score: 1695; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB7 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
190 200 210 220 230 240
pF1KB7 HELNHHDC
::::::::
XP_006 HELNHHDC
>>XP_005268703 (OMIM: 612568) PREDICTED: transcription f (248 aa)
initn: 1695 init1: 1695 opt: 1695 Z-score: 2082.7 bits: 392.9 E(85289): 2.9e-109
Smith-Waterman score: 1695; 100.0% identity (100.0% similar) in 248 aa overlap (1-248:1-248)
10 20 30 40 50 60
pF1KB7 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPVYNWRTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYNPEMASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EITKIRRKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANY
190 200 210 220 230 240
pF1KB7 HELNHHDC
::::::::
XP_005 HELNHHDC
>>XP_011518609 (OMIM: 165170) PREDICTED: transcription f (183 aa)
initn: 411 init1: 386 opt: 399 Z-score: 497.9 bits: 99.2 E(85289): 5.4e-21
Smith-Waterman score: 399; 57.7% identity (77.9% similar) in 104 aa overlap (97-200:70-172)
70 80 90 100 110 120
pF1KB7 RTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEM
: :: . :. .::.::...: . : . .:
XP_011 AQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGS-KKKIRLYQFLLDLLRSGDM
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR
. : :::: :: ::: ::.:: ::. :: .::::: ::::::::::::::..::. :..
XP_011 KDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 RKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHH
.::::::: .: :
XP_011 KKLTYQFSGEVLGRGGLAERRHPPH
160 170 180
>>XP_016873662 (OMIM: 165170) PREDICTED: transcription f (183 aa)
initn: 411 init1: 386 opt: 399 Z-score: 497.9 bits: 99.2 E(85289): 5.4e-21
Smith-Waterman score: 399; 57.7% identity (77.9% similar) in 104 aa overlap (97-200:70-172)
70 80 90 100 110 120
pF1KB7 RTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEM
: :: . :. .::.::...: . : . .:
XP_016 AQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGS-KKKIRLYQFLLDLLRSGDM
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR
. : :::: :: ::: ::.:: ::. :: .::::: ::::::::::::::..::. :..
XP_016 KDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 RKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHH
.::::::: .: :
XP_016 KKLTYQFSGEVLGRGGLAERRHPPH
160 170 180
>>NP_003111 (OMIM: 165170) transcription factor PU.1 iso (270 aa)
initn: 428 init1: 386 opt: 399 Z-score: 495.3 bits: 99.3 E(85289): 7.5e-21
Smith-Waterman score: 399; 57.7% identity (77.9% similar) in 104 aa overlap (97-200:157-259)
70 80 90 100 110 120
pF1KB7 RTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEM
: :: . :. .::.::...: . : . .:
NP_003 AQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGS-KKKIRLYQFLLDLLRSGDM
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB7 ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR
. : :::: :: ::: ::.:: ::. :: .::::: ::::::::::::::..::. :..
NP_003 KDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB7 RKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHH
.::::::: .: :
NP_003 KKLTYQFSGEVLGRGGLAERRHPPH
250 260 270
>>NP_001074016 (OMIM: 165170) transcription factor PU.1 (271 aa)
initn: 428 init1: 386 opt: 399 Z-score: 495.3 bits: 99.3 E(85289): 7.5e-21
Smith-Waterman score: 399; 57.7% identity (77.9% similar) in 104 aa overlap (97-200:158-260)
70 80 90 100 110 120
pF1KB7 RTVINSAADFYFEGNIHQSLQNITENQLVQPTLLQQKGGKGRKKLRLFEYLHESLYNPEM
: :: . :. .::.::...: . : . .:
NP_001 AQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGS-KKKIRLYQFLLDLLRSGDM
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB7 ASCIQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIR
. : :::: :: ::: ::.:: ::. :: .::::: ::::::::::::::..::. :..
NP_001 KDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGEVKKVK
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB7 RKLTYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHH
.::::::: .: :
NP_001 KKLTYQFSGEVLGRGGLAERRHPPH
250 260 270
>>NP_001230927 (OMIM: 606802) transcription factor Spi-B (171 aa)
initn: 397 init1: 375 opt: 378 Z-score: 472.6 bits: 94.4 E(85289): 1.4e-19
Smith-Waterman score: 378; 43.5% identity (68.0% similar) in 147 aa overlap (55-198:20-165)
30 40 50 60 70 80
pF1KB7 TGDLQYSPDYRNYLALINHRPHVKGNSSCYGVLPTEEPVYNWRT--VINSAADFYFEGNI
:.: :.: :.. :. ...
NP_001 MASSMTWTAASIPATLIQRGLLTLVPPAYAPYPSPVLSEEEDLPLDSPA
10 20 30 40
90 100 110 120 130 140
pF1KB7 HQSLQNITENQLVQ-PTLLQQKGGKGRKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQ
. .. ... :: : ...: ::::::...: : .: :. ::. :.::
NP_001 LEVSDSESDEALVAGPEGKGSEAGT-RKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQ
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB7 FVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRL
: ::.:: ::. ::..::::: :::::.:::::::...::: :..:::::::. :.:
NP_001 FSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAV
110 120 130 140 150 160
210 220 230 240
pF1KB7 SPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
NP_001 RRA
170
>>NP_003112 (OMIM: 606802) transcription factor Spi-B is (262 aa)
initn: 397 init1: 375 opt: 380 Z-score: 472.3 bits: 95.0 E(85289): 1.4e-19
Smith-Waterman score: 386; 36.0% identity (63.5% similar) in 200 aa overlap (11-198:59-256)
10 20 30 40
pF1KB7 MTCVEQDKLGQAFEDAFEVLRQHSTGDLQYSPDYRNYLAL
.::. : .. . ....: : : . .
NP_003 CKHSSYPDSEGAPDSLWDWTVAPPVPATPYEAFDPAAAAFSHPQAAQLCYEPPTYSPAGN
30 40 50 60 70 80
50 60 70 80 90
pF1KB7 INHRPHVKGNSSCYGVLPTEE--------PVYNWRT--VINSAADFYFEGNIHQSLQNIT
.. : ... . . :::. :.: :.. :. ... . .. .
NP_003 LELAPSLEAPGPGLPAYPTENFASQTLVPPAYAPYPSPVLSEEEDLPLDSPALEVSDSES
90 100 110 120 130 140
100 110 120 130 140
pF1KB7 ENQLVQPTLLQQKGGKG--RKKLRLFEYLHESLYNPEMASCIQWVDKTKGIFQFVSKNKE
.. :: . ::... ::::::...: : .: :. ::. :.::: ::.::
NP_003 DEALVAGP--EGKGSEAGTRKKLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKE
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB7 KLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKLTYQFSEAILQRLSPSYFLG
::. ::..::::: :::::.:::::::...::: :..:::::::. :.:
NP_003 LLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKLTYQFDSALLPAVRRA
210 220 230 240 250 260
210 220 230 240
pF1KB7 KEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
>>NP_001230929 (OMIM: 606802) transcription factor Spi-B (231 aa)
initn: 397 init1: 375 opt: 377 Z-score: 469.4 bits: 94.2 E(85289): 2.1e-19
Smith-Waterman score: 377; 57.6% identity (76.8% similar) in 99 aa overlap (105-198:127-225)
80 90 100 110 120
pF1KB7 DFYFEGNIHQSLQNITENQLVQPTLLQQKGGKG-----RKKLRLFEYLHESLYNPEMASC
::: ::::::...: : .: :
NP_001 LSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLTRGDMREC
100 110 120 130 140 150
130 140 150 160 170 180
pF1KB7 IQWVDKTKGIFQFVSKNKEKLAELWGKRKGNRKTMTYQKMARALRNYGRSGEITKIRRKL
. ::. :.::: ::.:: ::. ::..::::: :::::.:::::::...::: :..:::
NP_001 VWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEIRKVKRKL
160 170 180 190 200 210
190 200 210 220 230 240
pF1KB7 TYQFSEAILQRLSPSYFLGKEIFYSQCVQPDQEYLSLNNWNANYNYTYANYHELNHHDC
::::. :.:
NP_001 TYQFDSALLPAVRRA
220 230
248 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:45:20 2016 done: Sun Nov 6 14:45:21 2016
Total Scan time: 6.260 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]