Result of FASTA (omim) for
pFN21AB7153
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7153, 353 aa
1>>>pF1KB7153 353 - 353 aa - 353 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5207+/-0.00045; mu= 15.7476+/- 0.028
mean_var=133.8742+/-40.709, 0's: 0 Z-trim(112.0): 290 B-trim: 2506 in 2/47
Lambda= 0.110847
statistics sampled from 20283 (20828) to 20283 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.244), width: 16
Scan time: 8.160
The best scores are: opt bits E(85289)
NP_004221 (OMIM: 605111,610419,610419) sphingosine ( 353) 2306 380.9 2.4e-105
NP_005217 (OMIM: 601965) sphingosine 1-phosphate r ( 378) 1006 173.0 9.4e-43
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382) 814 142.3 1.7e-33
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382) 814 142.3 1.7e-33
NP_003766 (OMIM: 603751) sphingosine 1-phosphate r ( 384) 691 122.6 1.4e-27
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398) 674 119.9 9.3e-27
NP_001159687 (OMIM: 605146) sphingosine 1-phosphat ( 398) 674 119.9 9.3e-27
XP_016869886 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364) 546 99.4 1.3e-20
XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869880 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364) 546 99.4 1.3e-20
XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364) 546 99.4 1.3e-20
NP_036284 (OMIM: 605106) lysophosphatidic acid rec ( 353) 535 97.7 4.3e-20
XP_016882958 (OMIM: 605110) PREDICTED: lysophospha ( 351) 532 97.2 5.9e-20
XP_011526723 (OMIM: 605110) PREDICTED: lysophospha ( 351) 532 97.2 5.9e-20
XP_016882957 (OMIM: 605110) PREDICTED: lysophospha ( 351) 532 97.2 5.9e-20
NP_004711 (OMIM: 605110) lysophosphatidic acid rec ( 351) 532 97.2 5.9e-20
NP_005275 (OMIM: 600553) G-protein coupled recepto ( 362) 413 78.2 3.2e-14
NP_001273028 (OMIM: 600553) G-protein coupled rece ( 377) 413 78.2 3.3e-14
NP_005272 (OMIM: 600241) G-protein coupled recepto ( 330) 394 75.1 2.5e-13
NP_005279 (OMIM: 600752) G-protein coupled recepto ( 334) 386 73.8 6.1e-13
NP_063941 (OMIM: 155540,602025,607948) melanocorti ( 323) 384 73.5 7.5e-13
NP_005903 (OMIM: 155541,601665) melanocortin recep ( 332) 364 70.3 7e-12
NP_002377 (OMIM: 155555,203200,266300,613098,61309 ( 317) 326 64.2 4.6e-10
NP_001278840 (OMIM: 202200,607397) adrenocorticotr ( 297) 310 61.6 2.6e-09
NP_000520 (OMIM: 202200,607397) adrenocorticotropi ( 297) 310 61.6 2.6e-09
>>NP_004221 (OMIM: 605111,610419,610419) sphingosine 1-p (353 aa)
initn: 2306 init1: 2306 opt: 2306 Z-score: 2012.4 bits: 380.9 E(85289): 2.4e-105
Smith-Waterman score: 2306; 100.0% identity (100.0% similar) in 353 aa overlap (1-353:1-353)
10 20 30 40 50 60
pF1KB7 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
310 320 330 340 350
>>NP_005217 (OMIM: 601965) sphingosine 1-phosphate recep (378 aa)
initn: 967 init1: 693 opt: 1006 Z-score: 888.5 bits: 173.0 E(85289): 9.4e-43
Smith-Waterman score: 1006; 47.9% identity (77.7% similar) in 336 aa overlap (14-341:18-349)
10 20 30 40 50
pF1KB7 MGSLYSEYLNPNKVQEHYNYT-KETLETQETT-SRQVASAFIVILCCAIVVENLLV
..:::.:. : . . .:.. . .........: ::.:::.:
NP_005 MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 LIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFI
:::. .:.:::. ::.:.:::: :::::.:. .: :.::. :. :.:. :: :::: :.
NP_005 LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 TLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLG
.:.::. ::::::::::... :.. : ..: :..:::: :::...::.:::::::::
NP_005 ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 HLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMA----APQTLA
.: :::.::::.:.:. ..::. ::..:: ::.::: .:.:: .: . ...:
NP_005 NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 LLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTW
::.::.::..:::.:: : : ..:.: :: :..::::.::..:.....::: .::::::
NP_005 LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
250 260 270 280 290 300
300 310 320 330 340
pF1KB7 RSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLL-PLRS-SSSLERGMHMPTSPTFLE
:...:: .: : : . :.:: ..: . : : :: ::: . . : :
NP_005 ASKEMRRAFFR-LVC---NCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLP
310 320 330 340 350
350
pF1KB7 GNTVV
NP_005 HTAPSSCIMDKNAALQNGIFCN
360 370
>>NP_001307659 (OMIM: 601974) sphingosine 1-phosphate re (382 aa)
initn: 1101 init1: 747 opt: 814 Z-score: 722.5 bits: 142.3 E(85289): 1.7e-33
Smith-Waterman score: 1091; 48.4% identity (78.6% similar) in 345 aa overlap (3-333:14-358)
10 20 30 40
pF1KB7 MGSLYSEYLNPNKVQEHYNYT-KETLETQETTSRQVASAFIVILCCAIV
: :.:.: . . .::::: : .. ... .: ...:. ....:: :.
NP_001 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 VENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAR
.::..::... ...::: :: :.:::: ::::::::..:: ::::..: .:::.::: :
NP_001 LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 EGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPIL
::: :..:::::::::::::::.... :.::...... :..:::.: :.:::.::::::.
NP_001 EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
130 140 150 160 170 180
170 180 190 200 210
pF1KB7 GWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRS----------
::::.. : .:::::::: :::.: .:.:...::.:: :: ::: .::.
NP_001 GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB7 -SHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVS
:.:. .. ..::::::: :::.:::.:: : : .:::: .: :..: ::..:.::....
NP_001 ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 TLNSLLNPVIYTWRSRDLRREVLRPLQCWR-PGVGVQGR-RRGGTPGHHLLPLRSSSSLE
.::: ::.::: ....:: .: ..: . :. :. .: : .. .:..:
NP_001 VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
310 320 330 340 350 360
340 350
pF1KB7 RGMHMPTSPTFLEGNTVV
NP_001 PQKDEGDNPETIMSSGNVNSSS
370 380
>>NP_001391 (OMIM: 601974) sphingosine 1-phosphate recep (382 aa)
initn: 1101 init1: 747 opt: 814 Z-score: 722.5 bits: 142.3 E(85289): 1.7e-33
Smith-Waterman score: 1091; 48.4% identity (78.6% similar) in 345 aa overlap (3-333:14-358)
10 20 30 40
pF1KB7 MGSLYSEYLNPNKVQEHYNYT-KETLETQETTSRQVASAFIVILCCAIV
: :.:.: . . .::::: : .. ... .: ...:. ....:: :.
NP_001 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 VENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAR
.::..::... ...::: :: :.:::: ::::::::..:: ::::..: .:::.::: :
NP_001 LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 EGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPIL
::: :..:::::::::::::::.... :.::...... :..:::.: :.:::.::::::.
NP_001 EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
130 140 150 160 170 180
170 180 190 200 210
pF1KB7 GWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRS----------
::::.. : .:::::::: :::.: .:.:...::.:: :: ::: .::.
NP_001 GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB7 -SHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVS
:.:. .. ..::::::: :::.:::.:: : : .:::: .: :..: ::..:.::....
NP_001 ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 TLNSLLNPVIYTWRSRDLRREVLRPLQCWR-PGVGVQGR-RRGGTPGHHLLPLRSSSSLE
.::: ::.::: ....:: .: ..: . :. :. .: : .. .:..:
NP_001 VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
310 320 330 340 350 360
340 350
pF1KB7 RGMHMPTSPTFLEGNTVV
NP_001 PQKDEGDNPETIMSSGNVNSSS
370 380
>>NP_003766 (OMIM: 603751) sphingosine 1-phosphate recep (384 aa)
initn: 653 init1: 277 opt: 691 Z-score: 616.2 bits: 122.6 E(85289): 1.4e-27
Smith-Waterman score: 691; 41.8% identity (70.4% similar) in 280 aa overlap (41-314:54-333)
20 30 40 50 60 70
pF1KB7 PNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYL
: : .:.:::::: :.. . . . .:
NP_003 LIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYY
30 40 50 60 70 80
80 90 100 110 120 130
pF1KB7 FLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIER
: :.. ::::.:.:..::.::::. :.::.:.::: ::: : .:.::.:::: : ::
NP_003 CLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGER
90 100 110 120 130 140
140 150 160 170 180
pF1KB7 HVAIAK-VKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKH
..... : :. :. :. .:: ::.. .:: ::.:::::: .. ::..::::.:.
NP_003 FATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKR
150 160 170 180 190 200
190 200 210 220 230 240
pF1KB7 YVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAP----QTLALLKTVTIVLGVFIVC
:.: ..::. .: .:..:: :. .:..: : .. ::::: ..: .:.::
NP_003 YILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVC
210 220 230 240 250 260
250 260 270 280 290 300
pF1KB7 WLPAFSILLLD-YACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQ
: : :..:: : .. . . : ...:...::: .::.::..:::.. : :: :
NP_003 WGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLC
270 280 290 300 310 320
310 320 330 340 350
pF1KB7 CWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
: .:..:
NP_003 CGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRS
330 340 350 360 370 380
>>NP_110387 (OMIM: 605146) sphingosine 1-phosphate recep (398 aa)
initn: 950 init1: 643 opt: 674 Z-score: 601.3 bits: 119.9 E(85289): 9.3e-27
Smith-Waterman score: 943; 48.0% identity (70.8% similar) in 329 aa overlap (4-311:1-329)
10 20 30 40 50
pF1KB7 MGSLYSEYLNPNKVQE----HYNYT-KETLETQETTSRQVASAFIVILCCA-IVVENLLV
. : : : :.: ::::: : . . :.: . . :: ::.::: :
NP_110 MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAV
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 LIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFI
:....:. .::. :.:.::.:. ::::::.:..:: :::: .::.:.:. ::::::..:.
NP_110 LLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 TLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLG
.:.:::.::::::.:: ...:. .. : : . .:.: .::.:: :: :::::::
NP_110 ALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLG
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 HLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAA---------
.:.::::::::::: ::: : : :: :: :::.:::: ::.. . :
NP_110 RLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTS
180 190 200 210 220 230
230 240 250 260 270
pF1KB7 ------PQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTL
:..::::.:...:: .:..:: : : .:::: :::...::.: .: :....
NP_110 TRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB7 NSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMH
::::::.::: .::::. .:: . : : . :
NP_110 NSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLD
300 310 320 330 340 350
340 350
pF1KB7 MPTSPTFLEGNTVV
NP_110 GSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
360 370 380 390
>>NP_001159687 (OMIM: 605146) sphingosine 1-phosphate re (398 aa)
initn: 950 init1: 643 opt: 674 Z-score: 601.3 bits: 119.9 E(85289): 9.3e-27
Smith-Waterman score: 943; 48.0% identity (70.8% similar) in 329 aa overlap (4-311:1-329)
10 20 30 40 50
pF1KB7 MGSLYSEYLNPNKVQE----HYNYT-KETLETQETTSRQVASAFIVILCCA-IVVENLLV
. : : : :.: ::::: : . . :.: . . :: ::.::: :
NP_001 MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAV
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 LIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFI
:....:. .::. :.:.::.:. ::::::.:..:: :::: .::.:.:. ::::::..:.
NP_001 LLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 TLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLG
.:.:::.::::::.:: ...:. .. : : . .:.: .::.:: :: :::::::
NP_001 ALTASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLG
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 HLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAA---------
.:.::::::::::: ::: : : :: :: :::.:::: ::.. . :
NP_001 RLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTS
180 190 200 210 220 230
230 240 250 260 270
pF1KB7 ------PQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTL
:..::::.:...:: .:..:: : : .:::: :::...::.: .: :....
NP_001 TRARRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB7 NSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMH
::::::.::: .::::. .:: . : : . :
NP_001 NSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLD
300 310 320 330 340 350
340 350
pF1KB7 MPTSPTFLEGNTVV
NP_001 GSFSGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
360 370 380 390
>>XP_016869886 (OMIM: 602282) PREDICTED: lysophosphatidi (364 aa)
initn: 615 init1: 425 opt: 546 Z-score: 491.1 bits: 99.4 E(85289): 1.3e-20
Smith-Waterman score: 687; 34.5% identity (67.4% similar) in 322 aa overlap (18-326:34-352)
10 20 30 40
pF1KB7 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAI
:: . . : :. .: ... .. . .: :
XP_016 ISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 VVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFA
.. ::::..:. : .:: .: ...::::.:..::.:. . .: : ::: :.
XP_016 MLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 REGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPI
:.: .:.::: .:::::::::... ...:. .. :....: . : ...:.:..:
XP_016 RQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 LGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAI-VALYVRIYCVVRSSHADMA--
.::::. .: ::.. :::. : : .::... ... :.::..:. ::. :.
XP_016 VGWNCICDIENCSNMAPLYSDSY-LVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRH
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 --APQT-----LALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVS
.:. ..:::::.::::.::.:: :.. .:::: :: .: .: ..:. ..
XP_016 SSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCP--QCDVLAYEKFFLLLA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 TLNSLLNPVIYTWRSRDLRREVLRPLQCWR---PGVGVQGRRRGGTPGHHLLPLRSSSSL
.:: .::.::..:.... . : : : : ..: :... .: .
XP_016 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
310 320 330 340 350 360
340 350
pF1KB7 ERGMHMPTSPTFLEGNTVV
XP_016 HSVV
>>XP_016869896 (OMIM: 602282) PREDICTED: lysophosphatidi (364 aa)
initn: 615 init1: 425 opt: 546 Z-score: 491.1 bits: 99.4 E(85289): 1.3e-20
Smith-Waterman score: 687; 34.5% identity (67.4% similar) in 322 aa overlap (18-326:34-352)
10 20 30 40
pF1KB7 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAI
:: . . : :. .: ... .. . .: :
XP_016 ISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 VVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFA
.. ::::..:. : .:: .: ...::::.:..::.:. . .: : ::: :.
XP_016 MLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 REGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPI
:.: .:.::: .:::::::::... ...:. .. :....: . : ...:.:..:
XP_016 RQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 LGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAI-VALYVRIYCVVRSSHADMA--
.::::. .: ::.. :::. : : .::... ... :.::..:. ::. :.
XP_016 VGWNCICDIENCSNMAPLYSDSY-LVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRH
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 --APQT-----LALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVS
.:. ..:::::.::::.::.:: :.. .:::: :: .: .: ..:. ..
XP_016 SSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCP--QCDVLAYEKFFLLLA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 TLNSLLNPVIYTWRSRDLRREVLRPLQCWR---PGVGVQGRRRGGTPGHHLLPLRSSSSL
.:: .::.::..:.... . : : : : ..: :... .: .
XP_016 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
310 320 330 340 350 360
340 350
pF1KB7 ERGMHMPTSPTFLEGNTVV
XP_016 HSVV
>>NP_001392 (OMIM: 602282) lysophosphatidic acid recepto (364 aa)
initn: 615 init1: 425 opt: 546 Z-score: 491.1 bits: 99.4 E(85289): 1.3e-20
Smith-Waterman score: 687; 34.5% identity (67.4% similar) in 322 aa overlap (18-326:34-352)
10 20 30 40
pF1KB7 MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAI
:: . . : :. .: ... .. . .: :
NP_001 ISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 VVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFA
.. ::::..:. : .:: .: ...::::.:..::.:. . .: : ::: :.
NP_001 MLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 REGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPI
:.: .:.::: .:::::::::... ...:. .. :....: . : ...:.:..:
NP_001 RQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB7 LGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAI-VALYVRIYCVVRSSHADMA--
.::::. .: ::.. :::. : : .::... ... :.::..:. ::. :.
NP_001 VGWNCICDIENCSNMAPLYSDSY-LVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRH
190 200 210 220 230 240
230 240 250 260 270
pF1KB7 --APQT-----LALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVS
.:. ..:::::.::::.::.:: :.. .:::: :: .: .: ..:. ..
NP_001 SSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCP--QCDVLAYEKFFLLLA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 TLNSLLNPVIYTWRSRDLRREVLRPLQCWR---PGVGVQGRRRGGTPGHHLLPLRSSSSL
.:: .::.::..:.... . : : : : ..: :... .: .
NP_001 EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
310 320 330 340 350 360
340 350
pF1KB7 ERGMHMPTSPTFLEGNTVV
NP_001 HSVV
353 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:26:14 2016 done: Sun Nov 6 13:26:16 2016
Total Scan time: 8.160 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]