Result of FASTA (omim) for
pFN21AB6937
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6937, 210 aa
1>>>pF1KB6937 210 - 210 aa - 210 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3495+/-0.000311; mu= 10.5979+/- 0.019
mean_var=98.6826+/-19.880, 0's: 0 Z-trim(119.7): 25 B-trim: 1357 in 1/54
Lambda= 0.129108
statistics sampled from 34086 (34112) to 34086 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.4), width: 16
Scan time: 6.800
The best scores are: opt bits E(85289)
NP_057513 (OMIM: 615526) coatomer subunit zeta-2 [ ( 210) 1384 267.1 1.5e-71
XP_011523176 (OMIM: 615526) PREDICTED: coatomer su ( 184) 923 181.2 9.5e-46
NP_001258665 (OMIM: 615472) coatomer subunit zeta- ( 185) 871 171.5 7.9e-43
NP_057141 (OMIM: 615472) coatomer subunit zeta-1 i ( 177) 859 169.2 3.6e-42
NP_001258663 (OMIM: 615472) coatomer subunit zeta- ( 154) 738 146.7 1.9e-35
XP_016874486 (OMIM: 615472) PREDICTED: coatomer su ( 180) 727 144.7 9.2e-35
NP_001258664 (OMIM: 615472) coatomer subunit zeta- ( 160) 720 143.3 2.1e-34
XP_016864513 (OMIM: 601507) PREDICTED: AP-3 comple ( 262) 204 47.3 2.6e-05
XP_011541438 (OMIM: 601507) PREDICTED: AP-3 comple ( 262) 204 47.3 2.6e-05
NP_001305022 (OMIM: 601507) AP-3 complex subunit s ( 162) 193 45.2 7.3e-05
NP_005820 (OMIM: 602416) AP-3 complex subunit sigm ( 193) 188 44.3 0.00016
NP_001275 (OMIM: 601507) AP-3 complex subunit sigm ( 193) 186 43.9 0.00021
>>NP_057513 (OMIM: 615526) coatomer subunit zeta-2 [Homo (210 aa)
initn: 1384 init1: 1384 opt: 1384 Z-score: 1405.5 bits: 267.1 E(85289): 1.5e-71
Smith-Waterman score: 1384; 100.0% identity (100.0% similar) in 210 aa overlap (1-210:1-210)
10 20 30 40 50 60
pF1KB6 MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVN
130 140 150 160 170 180
190 200 210
pF1KB6 FRADDGGLTEQSVAQVLQSAKEQIKWSLLK
::::::::::::::::::::::::::::::
NP_057 FRADDGGLTEQSVAQVLQSAKEQIKWSLLK
190 200 210
>>XP_011523176 (OMIM: 615526) PREDICTED: coatomer subuni (184 aa)
initn: 1189 init1: 920 opt: 923 Z-score: 942.3 bits: 181.2 E(85289): 9.5e-46
Smith-Waterman score: 1141; 87.1% identity (87.6% similar) in 210 aa overlap (1-210:1-184)
10 20 30 40 50 60
pF1KB6 MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQRPEAWPRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKYYDDTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVN
:::::::::::::::::: .:::::::::::::::
XP_011 LMLMSVLTCLFESLNHML--------------------------SVILESDPQQVIQKVN
130 140 150
190 200 210
pF1KB6 FRADDGGLTEQSVAQVLQSAKEQIKWSLLK
::::::::::::::::::::::::::::::
XP_011 FRADDGGLTEQSVAQVLQSAKEQIKWSLLK
160 170 180
>>NP_001258665 (OMIM: 615472) coatomer subunit zeta-1 is (185 aa)
initn: 871 init1: 871 opt: 871 Z-score: 889.9 bits: 171.5 E(85289): 7.9e-43
Smith-Waterman score: 871; 75.1% identity (94.8% similar) in 173 aa overlap (38-210:13-185)
10 20 30 40 50 60
pF1KB6 PRPHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDT
::::::::.::..:::::: ::.:::::::
NP_001 MGGFRTEGMFVSLQEPSLYTVKAILILDNDGDRLFAKYYDDT
10 20 30 40
70 80 90 100 110 120
pF1KB6 FPSMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVL
.::.::: .::::.:::: ::.::::.. :.:.:::.::::..::.:::::::::::.::
NP_001 YPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 TCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGG
.:::.::..::::::::: :::::.: ::..:::::::::::::::::...: .:..:
NP_001 NCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVP
110 120 130 140 150 160
190 200 210
pF1KB6 LTEQSVAQVLQSAKEQIKWSLLK
::::.:.:::::::::::::::.
NP_001 LTEQTVSQVLQSAKEQIKWSLLR
170 180
>>NP_057141 (OMIM: 615472) coatomer subunit zeta-1 isofo (177 aa)
initn: 873 init1: 859 opt: 859 Z-score: 878.1 bits: 169.2 E(85289): 3.6e-42
Smith-Waterman score: 859; 74.9% identity (94.7% similar) in 171 aa overlap (40-210:7-177)
10 20 30 40 50 60
pF1KB6 PHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFP
::::::.::..:::::: ::.:::::::.:
NP_057 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYP
10 20 30
70 80 90 100 110 120
pF1KB6 SMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTC
:.::: .::::.:::: ::.::::.. :.:.:::.::::..::.:::::::::::.::.:
NP_057 SVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNC
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 LFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLT
::.::..::::::::: :::::.: ::..:::::::::::::::::...: .:..: ::
NP_057 LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLT
100 110 120 130 140 150
190 200 210
pF1KB6 EQSVAQVLQSAKEQIKWSLLK
::.:.:::::::::::::::.
NP_057 EQTVSQVLQSAKEQIKWSLLR
160 170
>>NP_001258663 (OMIM: 615472) coatomer subunit zeta-1 is (154 aa)
initn: 751 init1: 737 opt: 738 Z-score: 757.2 bits: 146.7 E(85289): 1.9e-35
Smith-Waterman score: 738; 73.5% identity (93.4% similar) in 151 aa overlap (60-210:4-154)
30 40 50 60 70 80
pF1KB6 AGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEKNVFNKTSRTE
: :::::.::.::: .::::.:::: ::.
NP_001 MEALILYYDDTYPSVKEQKAFEKNIFNKTHRTD
10 20 30
90 100 110 120 130 140
pF1KB6 SEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLE
::::.. :.:.:::.::::..::.:::::::::::.::.:::.::..::::::::: :::
NP_001 SEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 NMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLTEQSVAQVLQSAKEQIKWSLL
::.: ::..:::::::::::::::::...: .:..: ::::.:.:::::::::::::::
NP_001 NMEGLFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPLTEQTVSQVLQSAKEQIKWSLL
100 110 120 130 140 150
210
pF1KB6 K
.
NP_001 R
>>XP_016874486 (OMIM: 615472) PREDICTED: coatomer subuni (180 aa)
initn: 727 init1: 727 opt: 727 Z-score: 745.1 bits: 144.7 E(85289): 9.2e-35
Smith-Waterman score: 727; 74.8% identity (95.1% similar) in 143 aa overlap (40-182:7-149)
10 20 30 40 50 60
pF1KB6 PHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFP
::::::.::..:::::: ::.:::::::.:
XP_016 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYP
10 20 30
70 80 90 100 110 120
pF1KB6 SMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTC
:.::: .::::.:::: ::.::::.. :.:.:::.::::..::.:::::::::::.::.:
XP_016 SVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNC
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 LFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLT
::.::..::::::::: :::::.: ::..:::::::::::::::::...: .:
XP_016 LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRVALRVSKNVFL
100 110 120 130 140 150
190 200 210
pF1KB6 EQSVAQVLQSAKEQIKWSLLK
XP_016 CIPASIHKHPPEPDLLDVSSSWGS
160 170 180
>>NP_001258664 (OMIM: 615472) coatomer subunit zeta-1 is (160 aa)
initn: 796 init1: 720 opt: 720 Z-score: 738.8 bits: 143.3 E(85289): 2.1e-34
Smith-Waterman score: 761; 69.6% identity (86.5% similar) in 171 aa overlap (40-210:7-160)
10 20 30 40 50 60
pF1KB6 PHPGEGAAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFP
::::::.::..:::::: ::.:::::::.:
NP_001 MEALILEPSLYTVKAILILDNDGDRLFAKYYDDTYP
10 20 30
70 80 90 100 110 120
pF1KB6 SMKEQMVFEKNVFNKTSRTESEIAFFGGMTIVYKNSIDLFLYVVGSSYENELMLMSVLTC
:.::: .::::.:::: ::.::::.. :.:.:::.::::..::.:::::::::::.::.:
NP_001 SVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNC
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 LFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLT
::.::..::::::::: :::::.: ::..:::::::::::::::::...:
NP_001 LFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVILESDPQQVVHRV----------
100 110 120 130 140
190 200 210
pF1KB6 EQSVAQVLQSAKEQIKWSLLK
:::::::::::::.
NP_001 -------LQSAKEQIKWSLLR
150 160
>>XP_016864513 (OMIM: 601507) PREDICTED: AP-3 complex su (262 aa)
initn: 123 init1: 75 opt: 204 Z-score: 216.2 bits: 47.3 E(85289): 2.6e-05
Smith-Waterman score: 218; 26.5% identity (58.3% similar) in 223 aa overlap (2-202:47-260)
10 20 30
pF1KB6 MQRPEAWPRPHPGEGAAAAQAGGPAPPARAG
: : ::: : : ..::: . ::
XP_016 VSVLGRMRTLQLGRWLGPRNVSAFLSACPAQAPPLGPRPTARE-RARSRAGGGGWGRIAG
20 30 40 50 60 70
40 50 60 70
pF1KB6 EPS--GLRLQ----------EPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEK
: . : : . .:. :::..:..: :. :.:.:. . ..:.. .
XP_016 EITRRGSRARPRPGPQCPPGRPGTAMIKAILIFNNHGKPRLSKFYQPYSEDTQQQII--R
80 90 100 110 120 130
80 90 100 110 120
pF1KB6 NVFNKTSRTESEIAFF--GGMTI-------VYKNSIDL-FLYVVGSSYENELMLMSVLTC
..:. .:. . .. : ::. : .:.. : :.. : :: :.:: .....
XP_016 ETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSS-ESELGILDLIQV
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB6 LFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLT
. :.:.. . .:: . :. ..: . .: :.: ::..::.. .... .. : .
XP_016 FVETLDKCF-ENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQI----DAQNKL
200 210 220 230 240
190 200 210
pF1KB6 EQSVAQVLQSAKEQIKWSLLK
:.: . ..:: ..
XP_016 EKSETFIFQSPRQDR
250 260
>>XP_011541438 (OMIM: 601507) PREDICTED: AP-3 complex su (262 aa)
initn: 123 init1: 75 opt: 204 Z-score: 216.2 bits: 47.3 E(85289): 2.6e-05
Smith-Waterman score: 218; 26.5% identity (58.3% similar) in 223 aa overlap (2-202:47-260)
10 20 30
pF1KB6 MQRPEAWPRPHPGEGAAAAQAGGPAPPARAG
: : ::: : : ..::: . ::
XP_011 VSVLGRMRTLQLGRWLGPRNVSAFLSACPAQAPPLGPRPTARE-RARSRAGGGGWGRIAG
20 30 40 50 60 70
40 50 60 70
pF1KB6 EPS--GLRLQ----------EPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQMVFEK
: . : : . .:. :::..:..: :. :.:.:. . ..:.. .
XP_011 EITRRGSRARPRPGPQCPPGRPGTAMIKAILIFNNHGKPRLSKFYQPYSEDTQQQII--R
80 90 100 110 120 130
80 90 100 110 120
pF1KB6 NVFNKTSRTESEIAFF--GGMTI-------VYKNSIDL-FLYVVGSSYENELMLMSVLTC
..:. .:. . .. : ::. : .:.. : :.. : :: :.:: .....
XP_011 ETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSS-ESELGILDLIQV
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB6 LFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADDGGLT
. :.:.. . .:: . :. ..: . .: :.: ::..::.. .... .. : .
XP_011 FVETLDKCF-ENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQI----DAQNKL
200 210 220 230 240
190 200 210
pF1KB6 EQSVAQVLQSAKEQIKWSLLK
:.: . ..:: ..
XP_011 EKSETFIFQSPRQDR
250 260
>>NP_001305022 (OMIM: 601507) AP-3 complex subunit sigma (162 aa)
initn: 75 init1: 75 opt: 193 Z-score: 208.2 bits: 45.2 E(85289): 7.3e-05
Smith-Waterman score: 193; 25.7% identity (64.1% similar) in 167 aa overlap (46-202:2-160)
20 30 40 50 60 70
pF1KB6 AAAAQAGGPAPPARAGEPSGLRLQEPSLYTIKAVFILDNDGRRLLAKYYDDTFPSMKEQM
:::..:..: :. :.:.:. . ..:.
NP_001 MIKAILIFNNHGKPRLSKFYQPYSEDTQQQI
10 20 30
80 90 100 110 120
pF1KB6 VFEKNVFNKTSRTESEIAFF--GGMTI-------VYKNSIDL-FLYVVGSSYENELMLMS
. ...:. .:. . .. : ::. : .:.. : :.. : :: :.:: ...
NP_001 I--RETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSS-ESELGILD
40 50 60 70 80
130 140 150 160 170 180
pF1KB6 VLTCLFESLNHMLRKNVEKRWLLENMDGAFLVLDEIVDGGVILESDPQQVIQKVNFRADD
.. . :.:.. . .:: . :. ..: . .: :.: ::..::.. .... .. :
NP_001 LIQVFVETLDKCF-ENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQI----DA
90 100 110 120 130 140
190 200 210
pF1KB6 GGLTEQSVAQVLQSAKEQIKWSLLK
. :.: . ..:: ..
NP_001 QNKLEKSETFIFQSPRQDR
150 160
210 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:14:26 2016 done: Mon Nov 7 01:14:28 2016
Total Scan time: 6.800 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]