Result of FASTA (omim) for
pFN21AB6914
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6914, 225 aa
1>>>pF1KB6914 225 - 225 aa - 225 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7700+/-0.000358; mu= 11.1137+/- 0.022
mean_var=66.6287+/-13.124, 0's: 0 Z-trim(113.7): 15 B-trim: 33 in 1/53
Lambda= 0.157124
statistics sampled from 23131 (23146) to 23131 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.271), width: 16
Scan time: 5.990
The best scores are: opt bits E(85289)
NP_056202 (OMIM: 609361) MOB-like protein phocein ( 225) 1546 359.2 3.2e-99
NP_955776 (OMIM: 609361) MOB-like protein phocein ( 193) 1322 308.4 5.4e-84
NP_001191023 (OMIM: 609361) MOB-like protein phoce ( 193) 1322 308.4 5.4e-84
NP_001094289 (OMIM: 609361) MOB-like protein phoce ( 204) 1275 297.7 9.2e-81
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221) 199 53.8 2.6e-07
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase ( 221) 199 53.8 2.6e-07
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase ( 240) 199 53.9 2.8e-07
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216) 193 52.5 6.6e-07
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase ( 247) 193 52.5 7.4e-07
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215) 190 51.8 1.1e-06
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216) 190 51.8 1.1e-06
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258) 190 51.8 1.2e-06
>>NP_056202 (OMIM: 609361) MOB-like protein phocein isof (225 aa)
initn: 1546 init1: 1546 opt: 1546 Z-score: 1902.3 bits: 359.2 E(85289): 3.2e-99
Smith-Waterman score: 1546; 100.0% identity (100.0% similar) in 225 aa overlap (1-225:1-225)
10 20 30 40 50 60
pF1KB6 MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 AIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDE
130 140 150 160 170 180
190 200 210 220
pF1KB6 YENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
:::::::::::::::::::::::::::::::::::::::::::::
NP_056 YENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
190 200 210 220
>>NP_955776 (OMIM: 609361) MOB-like protein phocein isof (193 aa)
initn: 1322 init1: 1322 opt: 1322 Z-score: 1628.9 bits: 308.4 E(85289): 5.4e-84
Smith-Waterman score: 1322; 100.0% identity (100.0% similar) in 193 aa overlap (33-225:1-193)
10 20 30 40 50 60
pF1KB6 MAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPE
::::::::::::::::::::::::::::::
NP_955 MDSTLAVQQYIQQNIRADCSNIDKILEPPE
10 20 30
70 80 90 100 110 120
pF1KB6 GQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 GQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 DYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 DYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYE
100 110 120 130 140 150
190 200 210 220
pF1KB6 NETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
:::::::::::::::::::::::::::::::::::::::::::
NP_955 NETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
160 170 180 190
>>NP_001191023 (OMIM: 609361) MOB-like protein phocein i (193 aa)
initn: 1322 init1: 1322 opt: 1322 Z-score: 1628.9 bits: 308.4 E(85289): 5.4e-84
Smith-Waterman score: 1322; 100.0% identity (100.0% similar) in 193 aa overlap (33-225:1-193)
10 20 30 40 50 60
pF1KB6 MAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPE
::::::::::::::::::::::::::::::
NP_001 MDSTLAVQQYIQQNIRADCSNIDKILEPPE
10 20 30
70 80 90 100 110 120
pF1KB6 GQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECPAI
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 DYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYE
100 110 120 130 140 150
190 200 210 220
pF1KB6 NETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
:::::::::::::::::::::::::::::::::::::::::::
NP_001 NETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
160 170 180 190
>>NP_001094289 (OMIM: 609361) MOB-like protein phocein i (204 aa)
initn: 1275 init1: 1275 opt: 1275 Z-score: 1571.0 bits: 297.7 E(85289): 9.2e-81
Smith-Waterman score: 1343; 90.7% identity (90.7% similar) in 225 aa overlap (1-225:1-204)
10 20 30 40 50 60
pF1KB6 MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEP
:::::::::::::::::::: :::::::::::::::::::
NP_001 MVMAEGTAVLRRNRPGTKAQ---------------------YIQQNIRADCSNIDKILEP
10 20 30
70 80 90 100 110 120
pF1KB6 PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAHKTPKECP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 AIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIDYTRHTLDGAACLLNSNKYFPSRVSIKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDE
100 110 120 130 140 150
190 200 210 220
pF1KB6 YENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 YENETFLCHRFTKFVMKYNLMSKDNLIVPILEEEVQNSVSGESEA
160 170 180 190 200
>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is (221 aa)
initn: 78 init1: 38 opt: 199 Z-score: 252.2 bits: 53.8 E(85289): 2.6e-07
Smith-Waterman score: 199; 21.9% identity (55.2% similar) in 210 aa overlap (13-212:8-211)
10 20 30 40 50 60
pF1KB6 MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEP
:. :.... .. : ... : . . .. . .. . .:. .
NP_001 MEGATDVNESGSRSSKTFK-PKKNIPEGSHQYELLKHAEATLGS--GNLRMAVML
10 20 30 40 50
70 80 90 100 110
pF1KB6 PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAH---KTPK
:::.: . : . .: ..: : . . : ..: :.: .. . : : :
NP_001 PEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKES----SVAKLGSVCRRIYRIFSHAYFH
.: : : . . . :... :::.... :::: .. .:..:...: : .
NP_001 KCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAK--TILKRLFRVYAHIYHQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 HRQIFDEYENETFLCHRFTKF---VMKYNLMSKDNLIVPILEEEVQNSVSGESEA
: . . ..:. : : .: :...::... .: .:. :
NP_001 HFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRREL-APLQELIEKLTSKDR
180 190 200 210 220
>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti (221 aa)
initn: 78 init1: 38 opt: 199 Z-score: 252.2 bits: 53.8 E(85289): 2.6e-07
Smith-Waterman score: 199; 21.9% identity (55.2% similar) in 210 aa overlap (13-212:8-211)
10 20 30 40 50 60
pF1KB6 MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEP
:. :.... .. : ... : . . .. . .. . .:. .
XP_005 MEGATDVNESGSRSSKTFK-PKKNIPEGSHQYELLKHAEATLGS--GNLRMAVML
10 20 30 40 50
70 80 90 100 110
pF1KB6 PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCAAH---KTPK
:::.: . : . .: ..: : . . : ..: :.: .. . : : :
XP_005 PEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 ECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKES----SVAKLGSVCRRIYRIFSHAYFH
.: : : . . . :... :::.... :::: .. .:..:...: : .
XP_005 KCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAK--TILKRLFRVYAHIYHQ
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 HRQIFDEYENETFLCHRFTKF---VMKYNLMSKDNLIVPILEEEVQNSVSGESEA
: . . ..:. : : .: :...::... .: .:. :
XP_005 HFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRREL-APLQELIEKLTSKDR
180 190 200 210 220
>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti (240 aa)
initn: 78 init1: 38 opt: 199 Z-score: 251.6 bits: 53.9 E(85289): 2.8e-07
Smith-Waterman score: 199; 22.0% identity (55.0% similar) in 209 aa overlap (14-212:28-230)
10 20 30 40
pF1KB6 MVMAEGTAVLRRNRPGTKAQDFYNWPDESFDEMDSTLAVQQYIQQN
: :.... .. : ... : . . .. . .
XP_011 MTPNRVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFK-PKKNIPEGSHQYELLKHAEAT
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 IRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQW
. . .:. . :::.: . : . .: ..: : . . : ..: :.: ..
XP_011 LGS--GNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKY
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 IFLCAAH---KTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVSIKES----SVAKLGSV
. : : : .: : : . . . :... :::.... :::: ..
XP_011 EYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAK--TI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 CRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKF---VMKYNLMSKDNLIVPILEEEVQ
.:..:...: : .: . . ..:. : : .: :...::... .: .:. :
XP_011 LKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRREL-APLQELIEK
180 190 200 210 220 230
220
pF1KB6 NSVSGESEA
XP_011 LTSKDR
240
>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo (216 aa)
initn: 78 init1: 38 opt: 193 Z-score: 245.0 bits: 52.5 E(85289): 6.6e-07
Smith-Waterman score: 193; 25.3% identity (55.6% similar) in 162 aa overlap (61-212:48-206)
40 50 60 70 80 90
pF1KB6 DEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQS
:::.: . : . .: ..: : . .
NP_775 NIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITD
20 30 40 50 60 70
100 110 120 130 140
pF1KB6 ECHPDTCTQMTATEQWIFLCAAH---KTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVS
: ..: :.: .. . : : : .: : : . . . :... :::...
NP_775 FCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIG
80 90 100 110 120 130
150 160 170 180 190 200
pF1KB6 IKES----SVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKF---VMKYNL
. :::: .. .:..:...: : .: . . ..:. : : .: :...::
NP_775 VPFPKNFMSVAK--TILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNL
140 150 160 170 180 190
210 220
pF1KB6 MSKDNLIVPILEEEVQNSVSGESEA
... .: .:. :
NP_775 IDRREL-APLQELIEKLTSKDR
200 210
>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti (247 aa)
initn: 78 init1: 38 opt: 193 Z-score: 244.1 bits: 52.5 E(85289): 7.4e-07
Smith-Waterman score: 193; 25.3% identity (55.6% similar) in 162 aa overlap (61-212:79-237)
40 50 60 70 80 90
pF1KB6 DEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKLQS
:::.: . : . .: ..: : . .
XP_016 NIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITD
50 60 70 80 90 100
100 110 120 130 140
pF1KB6 ECHPDTCTQMTATEQWIFLCAAH---KTPKECPAIDYTRHTLDGAACLLNSNKYFPSRVS
: ..: :.: .. . : : : .: : : . . . :... :::...
XP_016 FCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIG
110 120 130 140 150 160
150 160 170 180 190 200
pF1KB6 IKES----SVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKF---VMKYNL
. :::: .. .:..:...: : .: . . ..:. : : .: :...::
XP_016 VPFPKNFMSVAK--TILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNL
170 180 190 200 210 220
210 220
pF1KB6 MSKDNLIVPILEEEVQNSVSGESEA
... .: .:. :
XP_016 IDRREL-APLQELIEKLTSKDR
230 240
>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is (215 aa)
initn: 78 init1: 38 opt: 190 Z-score: 241.4 bits: 51.8 E(85289): 1.1e-06
Smith-Waterman score: 190; 24.7% identity (54.1% similar) in 170 aa overlap (53-212:39-205)
30 40 50 60 70 80
pF1KB6 YNWPDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELN
:. . . :::.: . : . .: ..:
NP_001 SKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQIN
10 20 30 40 50 60
90 100 110 120 130
pF1KB6 GLAVKLQSECHPDTCTQMTATEQWIFLCAAH---KTPKECPAIDYTRHTLDGAACLLNSN
: . : .: :.: .. . : : : .: : : . . . :...
NP_001 MLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB6 KYFPSRVSIKES----SVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFLCHRFTKF-
:::.... :::: .. .:..:...: : .: . . ..:. : : .:
NP_001 TLFPSKIGVPFPKNFMSVAK--TILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFI
130 140 150 160 170 180
200 210 220
pF1KB6 --VMKYNLMSKDNLIVPILEEEVQNSVSGESEA
:...::... .: .:. :
NP_001 FFVQEFNLIDRREL-APLQELIEKLGSKDR
190 200 210
225 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:07:49 2016 done: Sun Nov 6 21:07:50 2016
Total Scan time: 5.990 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]